Signal Transduction Recent Publications

Miller CJ, Muftuoglu Y, Turk BE: A high throughput assay to identify substrate-selective inhibitors of the ERK protein kinases. Biochem Pharmacol. 2017 Oct 15; 2017 Jun 21. PMID: 28647489

Buas MF, He Q, Johnson LG, Onstad L, Levine DM, Thrift AP, Gharahkhani P, Palles C, Lagergren J, Fitzgerald RC, Ye W, Caldas C, Bird NC, Shaheen NJ, Bernstein L, Gammon MD, Wu AH, Hardie LJ, Pharoah PD, Liu G, Iyer P, Corley DA, Risch HA, Chow WH, Prenen H, Chegwidden L, Love S, Attwood S, Moayyedi P, MacDonald D, Harrison R, Watson P, Barr H, deCaestecker J, Tomlinson I, Jankowski J, Whiteman DC, MacGregor S, Vaughan TL, Madeleine MM: Germline variation in inflammation-related pathways and risk of Barrett's oesophagus and oesophageal adenocarcinoma. Gut. 2017 Oct; 2016 Aug 2. PMID: 27486097

Chae WJ, Park JH, Henegariu O, Yilmaz S, Hao L, Bothwell ALM: Membrane-bound Dickkopf-1 in Foxp3+ regulatory T cells suppresses T-cell-mediated autoimmune colitis. Immunology. 2017 Oct; 2017 Jun 27. PMID: 28556921

Theodosakis N, Micevic G, Langdon CG, Ventura A, Means R, Stern DF, Bosenberg MW: p90RSK Blockade Inhibits Dual BRAF and MEK Inhibitor-Resistant Melanoma by Targeting Protein Synthesis. J Invest Dermatol. 2017 Oct; 2017 Jun 7. PMID: 28599981

Kaczmarek LK, Zhang Y: Kv3 Channels: Enablers of Rapid Firing, Neurotransmitter Release, and Neuronal Endurance. Physiol Rev. 2017 Oct 1. PMID: 28904001

DeBerge M, Yeap XY, Dehn S, Zhang S, Grigoryeva L, Misener S, Procissi D, Zhou X, Lee DC, Muller WA, Luo X, Rothlin C, Tabas I, Thorp EB: MerTK Cleavage on Resident Cardiac Macrophages Compromises Repair After Myocardial Ischemia Reperfusion Injury. Circ Res. 2017 Sep 29; 2017 Aug 29. PMID: 28851810

Park J, Yang J, Wenzel AT, Ramachandran A, Lee WJ, Daniels JC, Kim J, Martinez-Escala E, Amankulor N, Pro B, Guitart J, Mendillo ML, Savas JN, Boggon TJ, Choi J: Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E). Blood. 2017 Sep 21; 2017 Jul 10. PMID: 28694326

Salazar SV, Gallardo C, Kaufman AC, Herber CS, Haas LT, Robinson S, Manson JC, Lee MK, Strittmatter SM: Conditional Deletion of Prnp Rescues Behavioral and Synaptic Deficits after Disease Onset in Transgenic Alzheimer's Disease. J Neurosci. 2017 Sep 20; 2017 Aug 21. PMID: 28842420

Stiegler AL, Boggon TJ: p190RhoGAP proteins contain pseudoGTPase domains. Nat Commun. 2017 Sep 11; 2017 Sep 11. PMID: 28894085

Suresh J, Harmston N, Lim KK, Kaur P, Jin HJ, Lusk JB, Petretto E, Tolwinski NS: An embryonic system to assess direct and indirect Wnt transcriptional targets. Sci Rep. 2017 Sep 11; 2017 Sep 11. PMID: 28894169

Ochi A, Chen D, Schulte W, Leng L, Moeckel N, Piecychna M, Averdunk L, Stoppe C, Bucala R, Moeckel G: MIF-2/D-DT enhances proximal tubular cell regeneration through SLPI- and ATF4-dependent mechanisms. Am J Physiol Renal Physiol. 2017 Sep 1; 2017 May 24. PMID: 28539339

Yoo Y, Jung J, Lee YN, Lee Y, Cho H, Na E, Hong J, Kim E, Lee JS, Lee JS, Hong C, Park SY, Wie J, Miller K, Shur N, Clow C, Ebel RS, DeBrosse SD, Henderson LB, Willaert R, Castaldi C, Tikhonova I, Bilgüvar K, Mane S, Kim KJ, Hwang YS, Lee SG, So I, Lim BC, Choi HJ, Seong JY, Shin YB, Jung H, Chae JH, Choi M: GABBR2 mutations determine phenotype in rett syndrome and epileptic encephalopathy. Ann Neurol. 2017 Sep. PMID: 28856709

Jiao Y, Li G, Li Q, Ali R, Qin L, Li W, Qyang Y, Greif DM, Geirsson A, Humphrey JD, Tellides G: mTOR (Mechanistic Target of Rapamycin) Inhibition Decreases Mechanosignaling, Collagen Accumulation, and Stiffening of the Thoracic Aorta in Elastin-Deficient Mice. Arterioscler Thromb Vasc Biol. 2017 Sep; 2017 Jul 27. PMID: 28751568

Zhang L, Fu Z, Li X, Tang H, Luo J, Zhang D, Zhuang Y, Han Z, Yin M: Transforming growth factor β-activated kinase 1 inhibitor suppresses the proliferation in triple-negative breast cancer through TGF-β/TGFR pathway. Chem Biol Drug Des. 2017 Sep; 2017 Apr 11. PMID: 28224764

Zhu X, Ding S, Qiu C, Shi Y, Song L, Wang Y, Wang Y, Li J, Wang Y, Sun Y, Qin L, Chen J, Simons M, Min W, Yu L: SUMOylation Negatively Regulates Angiogenesis by Targeting Endothelial NOTCH Signaling. Circ Res. 2017 Sep 1; 2017 Jul 31. PMID: 28760777

Tarafder S, Chen E, Jun Y, Kao K, Sim KH, Back J, Lee FY, Lee CH: Tendon stem/progenitor cells regulate inflammation in tendon healing via JNK and STAT3 signaling. FASEB J. 2017 Sep; 2017 May 22. PMID: 28533328

Cela P, Hampl M, Shylo NA, Christopher KJ, Kavkova M, Landova M, Zikmund T, Weatherbee SD, Kaiser J, Buchtova M: Ciliopathy Protein Tmem107 Plays Multiple Roles in Craniofacial Development. J Dent Res. 2017 Sep 1; 2017 Sep 1. PMID: 28954202

Whirledge S, Kisanga EP, Taylor RN, Cidlowski JA: Pioneer Factors FOXA1 and FOXA2 Assist Selective Glucocorticoid Receptor Signaling In Human Endometrial Cells. Endocrinology. 2017 Aug 29; 2017 Aug 29. PMID: 28938408

Nagarajan A, Dogra SK, Sun L, Gandotra N, Ho T, Cai G, Cline G, Kumar P, Cowles RA, Wajapeyee N: Paraoxonase 2 Facilitates Pancreatic Cancer Growth and Metastasis by Stimulating GLUT1-Mediated Glucose Transport. Mol Cell. 2017 Aug 17; 2017 Aug 10. PMID: 28803777

Peng L, Jia X, Zhao J, Cui R, Yan M: Substance P promotes hepatic stellate cell proliferation and activation via the TGF-β1/Smad-3 signaling pathway. Toxicol Appl Pharmacol. 2017 Aug 15; 2017 Jun 21. PMID: 28647476

Pradhan S, Khatlani T, Nairn AC, Vijayan KV: The heterotrimeric G protein Gβ1 interacts with the catalytic subunit of protein phosphatase 1 and modulates G protein-coupled receptor signaling in platelets. J Biol Chem. 2017 Aug 11; 2017 Jun 14. PMID: 28615442

Villarino GH, Hu Q, Scanlon MJ, Mueller L, Bombarely A, Mattson NS: Dissecting Tissue-Specific Transcriptomic Responses from Leaf and Roots under Salt Stress in Petunia hybrida Mitchell. Genes (Basel). 2017 Aug 3; 2017 Aug 3. PMID: 28771200

Ahn Y, Sims C, Murray MJ, Kuhlmann PK, Fuentes-Antrás J, Weatherbee SD, Krumlauf R: Multiple modes of Lrp4 function in modulation of Wnt/β-catenin signaling during tooth development. Development. 2017 Aug 1; 2017 Jul 10. PMID: 28694256

Kim JD, Toda C, Ramírez CM, Fernández-Hernando C, Diano S: Hypothalamic Ventromedial Lin28a Enhances Glucose Metabolism in Diet-Induced Obesity. Diabetes. 2017 Aug; 2017 May 26. PMID: 28550108

Zhang J, Karimy JK, Delpire E, Kahle KT: Pharmacological targeting of SPAK kinase in disorders of impaired epithelial transport. Expert Opin Ther Targets. 2017 Aug; 2017 Jul 12. PMID: 28679296

Vivante A, Mann N, Yonath H, Weiss AC, Getwan M, Kaminski MM, Bohnenpoll T, Teyssier C, Chen J, Shril S, van der Ven AT, Ityel H, Schmidt JM, Widmeier E, Bauer SB, Sanna-Cherchi S, Gharavi AG, Lu W, Magen D, Shukrun R, Lifton RP, Tasic V, Stanescu HC, Cavaillès V, Kleta R, Anikster Y, Dekel B, Kispert A, Lienkamp SS, Hildebrandt F: A Dominant Mutation in Nuclear Receptor Interacting Protein 1 Causes Urinary Tract Malformations via Dysregulation of Retinoic Acid Signaling. J Am Soc Nephrol. 2017 Aug; 2017 Apr 5. PMID: 28381549

Bhuiyan MIH, Song S, Yuan H, Begum G, Kofler J, Kahle KT, Yang SS, Lin SH, Alper SL, Subramanya AR, Sun D: WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic brain damage in hypertensive rats. J Cereb Blood Flow Metab. 2017 Aug; 2016 Jan 1. PMID: 27798271

Sweet RA, Nickerson KM, Cullen JL, Wang Y, Shlomchik MJ: B Cell-Extrinsic Myd88 and Fcer1g Negatively Regulate Autoreactive and Normal B Cell Immune Responses. J Immunol. 2017 Aug 1; 2017 Jun 28. PMID: 28659358

Gibb DR, Liu J, Natarajan P, Santhanakrishnan M, Madrid DJ, Eisenbarth SC, Zimring JC, Iwasaki A, Hendrickson JE: Type I IFN Is Necessary and Sufficient for Inflammation-Induced Red Blood Cell Alloimmunization in Mice. J Immunol. 2017 Aug 1; 2017 Jun 19. PMID: 28630094

Whirledge SD, Jewell CM, Barber LM, Xu X, Katen KS, Garantziotis S, Cidlowski JA: Generating diversity in human glucocorticoid signaling through a racially diverse polymorphism in the beta isoform of the glucocorticoid receptor. Lab Invest. 2017 Jul 31; 2017 Jul 31. PMID: 28759007

Hannemann S, Galán JE: Salmonella enterica serovar-specific transcriptional reprogramming of infected cells. PLoS Pathog. 2017 Jul; 2017 Jul 24. PMID: 28742135

Alvarado D, Ligon GF, Lillquist JS, Seibel SB, Wallweber G, Neumeister VM, Rimm DL, McMahon G, LaVallee TM: ErbB activation signatures as potential biomarkers for anti-ErbB3 treatment in HNSCC. PLoS One. 2017; 2017 Jul 19. PMID: 28723928

Cui Y, Zhu C, Ming Z, Cao J, Yan Y, Zhao P, Pang G, Deng Z, Yao Y, Chen Q: Molecular mechanisms by which casein glycomacropeptide maintains internal homeostasis in mice with experimental ulcerative colitis. PLoS One. 2017; 2017 Jul 10. PMID: 28700735

Haas LT, Salazar SV, Smith LM, Zhao HR, Cox TO, Herber CS, Degnan AP, Balakrishnan A, Macor JE, Albright CF, Strittmatter SM: Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes. Cell Rep. 2017 Jul 5. PMID: 28683325

Efimova N, Korobova F, Stankewich MC, Moberly AH, Stolz DB, Wang J, Kashina A, Ma M, Svitkina T: βIII Spectrin Is Necessary for Formation of the Constricted Neck of Dendritic Spines and Regulation of Synaptic Activity in Neurons. J Neurosci. 2017 Jul 5; 2017 Jun 2. PMID: 28576936

Chowdhury GMI, Wang P, Ciardi A, Mamillapalli R, Johnson J, Zhu W, Eid T, Behar K, Chan O: Impaired Glutamatergic Neurotransmission in the Ventromedial Hypothalamus May Contribute to Defective Counterregulation in Recurrently Hypoglycemic Rats. Diabetes. 2017 Jul; 2017 Apr 17. PMID: 28416628

Maguire CA, Song YB, Wu M, León S, Carroll RS, Alreja M, Kaiser UB, Navarro VM: Tac1 Signaling Is Required for Sexual Maturation and Responsiveness of GnRH Neurons to Kisspeptin in the Male Mouse. Endocrinology. 2017 Jul 1. PMID: 28444173

Erkenbrack EM, Petsios E: A Conserved Role for VEGF Signaling in Specification of Homologous Mesenchymal Cell Types Positioned at Spatially Distinct Developmental Addresses in Early Development of Sea Urchins. J Exp Zool B Mol Dev Evol. 2017 Jul; 2017 May 23. PMID: 28544452

Murrough JW, Abdallah CG, Mathew SJ: Targeting glutamate signalling in depression: progress and prospects. Nat Rev Drug Discov. 2017 Jul; 2017 Mar 17. PMID: 28303025

Yang X, Qian K: Protein O-GlcNAcylation: emerging mechanisms and functions. Nat Rev Mol Cell Biol. 2017 Jul; 2017 May 10. PMID: 28488703

Almadanim MC, Alexandre BM, Rosa MTG, Sapeta H, Leitão AE, Ramalho JC, Lam TT, Negrão S, Abreu IA, Oliveira MM: Rice calcium-dependent protein kinase OsCPK17 targets plasma membrane intrinsic protein and sucrose-phosphate synthase and is required for a proper cold stress response. Plant Cell Environ. 2017 Jul; 2017 Mar 2. PMID: 28102545

Huang J, Vanoye CG, Cutts A, Goldberg YP, Dib-Hajj SD, Cohen CJ, Waxman SG, George AL Jr: Sodium channel NaV1.9 mutations associated with insensitivity to pain dampen neuronal excitability. J Clin Invest. 2017 Jun 30; 2017 May 22. PMID: 28530638

Gorur-Shandilya S, Demir M, Long J, Clark DA, Emonet T: Olfactory receptor neurons use gain control and complementary kinetics to encode intermittent odorant stimuli. Elife. 2017 Jun 28; 2017 Jun 28. PMID: 28653907

Saheki Y, De Camilli P: Endoplasmic Reticulum-Plasma Membrane Contact Sites. Annu Rev Biochem. 2017 Jun 20; 2017 Feb 23. PMID: 28301744

Horsley V, Naik S: Tregs Expand the Skin Stem Cell Niche. Dev Cell. 2017 Jun 5. PMID: 28586641

Li G, Qin L, Wang L, Li X, Caulk AW, Zhang J, Chen PY, Xin S: Inhibition of the mTOR pathway in abdominal aortic aneurysm: implications of smooth muscle cell contractile phenotype, inflammation, and aneurysm expansion. Am J Physiol Heart Circ Physiol. 2017 Jun 1; 2017 Feb 17. PMID: 28213405

Kuwahara G, Hashimoto T, Tsuneki M, Yamamoto K, Assi R, Foster TR, Hanisch JJ, Bai H, Hu H, Protack CD, Hall MR, Schardt JS, Jay SM, Madri JA, Kodama S, Dardik A: CD44 Promotes Inflammation and Extracellular Matrix Production During Arteriovenous Fistula Maturation. Arterioscler Thromb Vasc Biol. 2017 Jun; 2017 Apr 27. PMID: 28450292

Gifford GB, Demitrack ES, Keeley TM, Tam A, La Cunza N, Dedhia PH, Spence JR, Simeone DM, Saotome I, Louvi A, Siebel CW, Samuelson LC: Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis. Gut. 2017 Jun; 2016 Mar 1. PMID: 26933171

Wang T, Weinbaum S, Weinstein AM: Regulation of glomerulotubular balance: flow-activated proximal tubule function. Pflugers Arch. 2017 Jun; 2017 Mar 7. PMID: 28271233

Whirledge S, Cidlowski JA: Glucocorticoids and Reproduction: Traffic Control on the Road to Reproduction. Trends Endocrinol Metab. 2017 Jun; 2017 Mar 6. PMID: 28274682

Vonhoff F, Keshishian H: In Vivo Calcium Signaling during Synaptic Refinement at the Drosophila Neuromuscular Junction. J Neurosci. 2017 May 31; 2017 May 5. PMID: 28476946

Yu P, Wilhelm K, Dubrac A, Tung JK, Alves TC, Fang JS, Xie Y, Zhu J, Chen Z, De Smet F, Zhang J, Jin SW, Sun L, Sun H, Kibbey RG, Hirschi KK, Hay N, Carmeliet P, Chittenden TW, Eichmann A, Potente M, Simons M: FGF-dependent metabolic control of vascular development. Nature. 2017 May 11; 2017 May 3. PMID: 28467822

Ardiel EL, Kumar A, Marbach J, Christensen R, Gupta R, Duncan W, Daniels JS, Stuurman N, Colón-Ramos D, Shroff H: Visualizing Calcium Flux in Freely Moving Nematode Embryos. Biophys J. 2017 May 9. PMID: 28494967

Kruglov E, Ananthanarayanan M, Sousa P, Weerachayaphorn J, Guerra MT, Nathanson MH: Type 2 inositol trisphosphate receptor gene expression in hepatocytes is regulated by cyclic AMP. Biochem Biophys Res Commun. 2017 May 6; 2017 Mar 19. PMID: 28327356

Menderes G, Bonazzoli E, Bellone S, Black JD, Lopez S, Pettinella F, Masserdotti A, Zammataro L, Litkouhi B, Ratner E, Silasi DA, Azodi M, Schwartz PE, Santin AD: Efficacy of neratinib in the treatment of HER2/neu-amplified epithelial ovarian carcinoma in vitro and in vivo. Med Oncol. 2017 May; 2017 Apr 10. PMID: 28397106

Chorzalska A, Kim JF, Roder K, Tepper A, Ahsan N, Rao RSP, Olszewski AJ, Yu X, Terentyev D, Morgan J, Treaba DO, Zhao TC, Liang O, Gruppuso PA, Dubielecka PM: Long-Term Exposure to Imatinib Mesylate Downregulates Hippo Pathway and Activates YAP in a Model of Chronic Myelogenous Leukemia. Stem Cells Dev. 2017 May 1; 2017 Feb 27. PMID: 28103766

Siller R, Dufour E, Lycke M, Wilmut I, Jung YW, Park IH, Sullivan GJ: Development of an inducible platform for intercellular protein delivery. Int J Pharm. 2017 Apr 30; 2017 Feb 28. PMID: 28254654

Heinolainen K, Karaman S, D'Amico G, Tammela T, Sormunen R, Eklund L, Alitalo K, Zarkada G: VEGFR3 Modulates Vascular Permeability by Controlling VEGF/VEGFR2 Signaling. Circ Res. 2017 Apr 28; 2017 Mar 15. PMID: 28298294

Zhong T, Men Y, Lu L, Geng T, Zhou J, Mitsuhashi A, Shozu M, Maihle NJ, Carmichael GG, Taylor HS, Huang Y: Metformin alters DNA methylation genome-wide via the H19/SAHH axis. Oncogene. 2017 Apr 27; 2016 Oct 24. PMID: 27775072

Ottis P, Crews CM: Proteolysis-Targeting Chimeras: Induced Protein Degradation as a Therapeutic Strategy. ACS Chem Biol. 2017 Apr 21; 2017 Mar 20. PMID: 28263557

Jeong J, VanHouten JN, Kim W, Dann P, Sullivan C, Choi J, Sneddon WB, Friedman PA, Wysolmerski JJ: The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2. J Biol Chem. 2017 Apr 21; 2017 Feb 24. PMID: 28235801

Mak TW, Grusdat M, Duncan GS, Dostert C, Nonnenmacher Y, Cox M, Binsfeld C, Hao Z, Brüstle A, Itsumi M, Jäger C, Chen Y, Pinkenburg O, Camara B, Ollert M, Bindslev-Jensen C, Vasiliou V, Gorrini C, Lang PA, Lohoff M, Harris IS, Hiller K, Brenner D: Glutathione Primes T Cell Metabolism for Inflammation. Immunity. 2017 Apr 18. PMID: 28423341

Xin D, Christopher KJ, Zeng L, Kong Y, Weatherbee SD: IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture. Development. 2017 Apr 15; 2017 Mar 6. PMID: 28264835

Spadaro O, Camell CD, Bosurgi L, Nguyen KY, Youm YH, Rothlin CV, Dixit VD: IGF1 Shapes Macrophage Activation in Response to Immunometabolic Challenge. Cell Rep. 2017 Apr 11. PMID: 28402847

Habibi I, Cheong R, Lipniacki T, Levchenko A, Emamian ES, Abdi A: Computation and measurement of cell decision making errors using single cell data. PLoS Comput Biol. 2017 Apr; 2017 Apr 5. PMID: 28379950

Zhang C, Wang L, Su XT, Zhang J, Lin DH, Wang WH: ENaC and ROMK activity are inhibited in the DCT2/CNT of TgWnk4PHAII mice. Am J Physiol Renal Physiol. 2017 Apr 1; 2016 Nov 9. PMID: 28365586

Kim S, Kwok S, Mayes LC, Potenza MN, Rutherford HJV, Strathearn L: Early adverse experience and substance addiction: dopamine, oxytocin, and glucocorticoid pathways. Ann N Y Acad Sci. 2017 Apr; 2016 Aug 10. PMID: 27508337

Lee HW, Chong DC, Ola R, Dunworth WP, Meadows S, Ka J, Kaartinen VM, Qyang Y, Cleaver O, Bautch VL, Eichmann A, Jin SW: Alk2/ACVR1 and Alk3/BMPR1A Provide Essential Function for Bone Morphogenetic Protein-Induced Retinal Angiogenesis. Arterioscler Thromb Vasc Biol. 2017 Apr; 2017 Feb 23. PMID: 28232325

Somarelli JA, Ware KE, Kostadinov R, Robinson JM, Amri H, Abu-Asab M, Fourie N, Diogo R, Swofford D, Townsend JP: PhyloOncology: Understanding cancer through phylogenetic analysis. Biochim Biophys Acta. 2017 Apr; 2016 Oct 31. PMID: 27810337

Griffith OW, Brandley MC, Whittington CM, Belov K, Thompson MB: Comparative genomics of hormonal signaling in the chorioallantoic membrane of oviparous and viviparous amniotes. Gen Comp Endocrinol. 2017 Apr 1; 2016 Apr 19. PMID: 27102939

Damsky W, King BA: JAK inhibitors in dermatology: The promise of a new drug class. J Am Acad Dermatol. 2017 Apr; 2017 Jan 28. PMID: 28139263

Lou H, Lu J, Choi EB, Oh MH, Jeong M, Barmettler S, Zhu Z, Zheng T: Expression of IL-22 in the Skin Causes Th2-Biased Immunity, Epidermal Barrier Dysfunction, and Pruritus via Stimulating Epithelial Th2 Cytokines and the GRP Pathway. J Immunol. 2017 Apr 1; 2017 Feb 22. PMID: 28228560

Olson KM, Lei W, Keresztes A, LaVigne J, Streicher JM: Novel Molecular Strategies and Targets for Opioid Drug Discovery for the Treatment of Chronic Pain. Yale J Biol Med. 2017 Mar; 2017 Mar 29. PMID: 28356897

Bear A, Prudic KL, Monteiro A: Steroid hormone signaling during development has a latent effect on adult male sexual behavior in the butterfly Bicyclus anynana. PLoS One. 2017; 2017 Mar 22. PMID: 28328961

Chang C, Liu T, Huang Y, Qin W, Yang H, Chen J: MicroRNA-134-3p is a novel potential inhibitor of human ovarian cancer stem cells by targeting RAB27A. Gene. 2017 Mar 20; 2016 Dec 31. PMID: 28043921

Kroczynska B, Blyth GT, Rafidi RL, Majchrzak-Kita B, Xu L, Saleiro D, Kosciuczuk EM, Jemielity J, Su B, Altman JK, Eklund EA, Fish EN, Platanias LC: Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses. J Biol Chem. 2017 Mar 17; 2017 Feb 7. PMID: 28174303

Song HS, Kwon OS, Kim JH, Conde J, Artzi N: 3D hydrogel scaffold doped with 2D graphene materials for biosensors and bioelectronics. Biosens Bioelectron. 2017 Mar 15; 2016 Mar 19. PMID: 27020065

Kim AR, Ulirsch JC, Wilmes S, Unal E, Moraga I, Karakukcu M, Yuan D, Kazerounian S, Abdulhay NJ, King DS, Gupta N, Gabriel SB, Lander ES, Patiroglu T, Ozcan A, Ozdemir MA, Garcia KC, Piehler J, Gazda HT, Klein DE, Sankaran VG: Functional Selectivity in Cytokine Signaling Revealed Through a Pathogenic EPO Mutation. Cell. 2017 Mar 9. PMID: 28283061

Andrade EC, Musante V, Horiuchi A, Matsuzaki H, Brody AH, Wu T, Greengard P, Taylor JR, Nairn AC: ARPP-16 Is a Striatal-Enriched Inhibitor of Protein Phosphatase 2A Regulated by Microtubule-Associated Serine/Threonine Kinase 3 (Mast 3 Kinase). J Neurosci. 2017 Mar 8; 2017 Feb 6. PMID: 28167675

Milovanovic D, De Camilli P: Synaptic Vesicle Clusters at Synapses: A Distinct Liquid Phase? Neuron. 2017 Mar 8. PMID: 28279363

Yamasaki T, Hoyos-Ramirez E, Martenson JS, Morimoto-Tomita M, Tomita S: GARLH Family Proteins Stabilize GABAA Receptors at Synapses. Neuron. 2017 Mar 8. PMID: 28279354

Fan Y, Hanai JI, Le PT, Bi R, Maridas D, DeMambro V, Figueroa CA, Kir S, Zhou X, Mannstadt M, Baron R, Bronson RT, Horowitz MC, Wu JY, Bilezikian JP, Dempster DW, Rosen CJ, Lanske B: Parathyroid Hormone Directs Bone Marrow Mesenchymal Cell Fate. Cell Metab. 2017 Mar 7; 2017 Feb 2. PMID: 28162969

Lee H, Min K, Yi JS, Shi H, Chang W, Jackson L, Bennett AM: A Phosphoproteomic Screen Identifies a Guanine Nucleotide Exchange Factor for Rab3A Protein as a Mitogen-activated Protein (MAP) Kinase Phosphatase-5-regulated MAP Kinase Target in Interleukin 6 (IL-6) Secretion and Myogenesis. J Biol Chem. 2017 Mar 3; 2017 Jan 17. PMID: 28096466

Han CK, Tien YC, Jine-Yuan Hsieh D, Ho TJ, Lai CH, Yeh YL, Hsuan Day C, Shen CY, Hsu HH, Lin JY, Huang CY: Attenuation of the LPS-induced, ERK-mediated upregulation of fibrosis-related factors FGF-2, uPA, MMP-2, and MMP-9 by Carthamus tinctorius L in cardiomyoblasts. Environ Toxicol. 2017 Mar; 2016 Apr 20. PMID: 27098997

Akalu YT, Rothlin CV, Ghosh S: TAM receptor tyrosine kinases as emerging targets of innate immune checkpoint blockade for cancer therapy. Immunol Rev. 2017 Mar. PMID: 28258690

Oren DA, Duda M, Kozioł K, Romerowicz-Misielak M, Koziorowska A, Sołek P, Nowak S, Kulpa M, Koziorowski M: Retinal venous blood carbon monoxide response to bright light in male pigs: A preliminary study. J Photochem Photobiol B. 2017 Mar; 2017 Jan 21. PMID: 28135573

Ogawa LM, Baserga SJ: Crosstalk between the nucleolus and the DNA damage response. Mol Biosyst. 2017 Feb 28. PMID: 28112326

Lauridsen HM, Gonzalez AL: Biomimetic, ultrathin and elastic hydrogels regulate human neutrophil extravasation across endothelial-pericyte bilayers. PLoS One. 2017; 2017 Feb 24. PMID: 28234918

Burk K, Mire E, Bellon A, Hocine M, Guillot J, Moraes F, Yoshida Y, Simons M, Chauvet S, Mann F: Post-endocytic sorting of Plexin-D1 controls signal transduction and development of axonal and vascular circuits. Nat Commun. 2017 Feb 22; 2017 Feb 22. PMID: 28224988

Salazar SV, Strittmatter SM: Cellular prion protein as a receptor for amyloid-β oligomers in Alzheimer's disease. Biochem Biophys Res Commun. 2017 Feb 19; 2016 Sep 14. PMID: 27639648

Bogusz AM, Kovach AE, Le LP, Feng D, Baxter RH, Sohani AR: Diffuse large B-cell lymphoma with concurrent high MYC and BCL2 expression shows evidence of active B-cell receptor signaling by quantitative immunofluorescence. PLoS One. 2017; 2017 Feb 17. PMID: 28212447

Lees JA, Messa M, Sun EW, Wheeler H, Torta F, Wenk MR, De Camilli P, Reinisch KM: Lipid transport by TMEM24 at ER-plasma membrane contacts regulates pulsatile insulin secretion. Science. 2017 Feb 17. PMID: 28209843

Mueller M, Oppliger B, Joerger-Messerli M, Reinhart U, Barnea E, Paidas M, Kramer BW, Surbek DV, Schoeberlein A: Wharton's Jelly Mesenchymal Stem Cells Protect the Immature Brain in Rats and Modulate Cell Fate. Stem Cells Dev. 2017 Feb 15; 2016 Dec 16. PMID: 27842457

Corbit KC, Camporez JP, Tran JL, Wilson CG, Lowe DA, Nordstrom SM, Ganeshan K, Perry RJ, Shulman GI, Jurczak MJ, Weiss EJ: Adipocyte JAK2 mediates growth hormone-induced hepatic insulin resistance. JCI Insight. 2017 Feb 9; 2017 Feb 9. PMID: 28194444

Thoreen CC: The molecular basis of mTORC1-regulated translation. Biochem Soc Trans. 2017 Feb 8. PMID: 28202675

Ryglewski S, Vonhoff F, Scheckel K, Duch C: Intra-neuronal Competition for Synaptic Partners Conserves the Amount of Dendritic Building Material. Neuron. 2017 Feb 8; 2017 Jan 26. PMID: 28132832

Shekarabi M, Zhang J, Khanna AR, Ellison DH, Delpire E, Kahle KT: WNK Kinase Signaling in Ion Homeostasis and Human Disease. Cell Metab. 2017 Feb 7. PMID: 28178566

Hankir MK, Seyfried F, Hintschich CA, Diep TA, Kleberg K, Kranz M, Deuther-Conrad W, Tellez LA, Rullmann M, Patt M, Teichert J, Hesse S, Sabri O, Brust P, Hansen HS, de Araujo IE, Krügel U, Fenske WK: Gastric Bypass Surgery Recruits a Gut PPAR-α-Striatal D1R Pathway to Reduce Fat Appetite in Obese Rats. Cell Metab. 2017 Feb 7; 2017 Jan 5. PMID: 28065827

Hu Y, O'Boyle K, Auer J, Raju S, You F, Wang P, Fikrig E, Sutton RE: Multiple UBXN family members inhibit retrovirus and lentivirus production and canonical NFκΒ signaling by stabilizing IκBα. PLoS Pathog. 2017 Feb; 2017 Feb 2. PMID: 28152074

Ceneri N, Zhao L, Young BD, Healy A, Coskun S, Vasavada H, Yarovinsky TO, Ike K, Pardi R, Qin L, Qin L, Tellides G, Hirschi K, Meadows J, Soufer R, Chun HJ, Sadeghi MM, Bender JR, Morrison AR: Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production. Arterioscler Thromb Vasc Biol. 2017 Feb; 2016 Nov 10. PMID: 27834690

Heit C, Marshall S, Singh S, Yu X, Charkoftaki G, Zhao H, Orlicky DJ, Fritz KS, Thompson DC, Vasiliou V: Catalase deletion promotes prediabetic phenotype in mice. Free Radic Biol Med. 2017 Feb; 2016 Dec 8. PMID: 27939935

Abraham C, Dulai PS, Vermeire S, Sandborn WJ: Lessons Learned From Trials Targeting Cytokine Pathways in Patients With Inflammatory Bowel Diseases. Gastroenterology. 2017 Feb; 2016 Oct 22. PMID: 27780712

Brockmann L, Gagliani N, Steglich B, Giannou AD, Kempski J, Pelczar P, Geffken M, Mfarrej B, Huber F, Herkel J, Wan YY, Esplugues E, Battaglia M, Krebs CF, Flavell RA, Huber S: IL-10 Receptor Signaling Is Essential for TR1 Cell Function In Vivo. J Immunol. 2017 Feb 1; 2016 Dec 21. PMID: 28003377

Romanov RA, Zeisel A, Bakker J, Girach F, Hellysaz A, Tomer R, Alpár A, Mulder J, Clotman F, Keimpema E, Hsueh B, Crow AK, Martens H, Schwindling C, Calvigioni D, Bains JS, Máté Z, Szabó G, Yanagawa Y, Zhang MD, Rendeiro A, Farlik M, Uhlén M, Wulff P, Bock C, Broberger C, Deisseroth K, Hökfelt T, Linnarsson S, Horvath TL, Harkany T: Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes. Nat Neurosci. 2017 Feb; 2016 Dec 19. PMID: 27991900

He X, Zhang W, Yan C, Nie F, Li C, Liu X, Fei C, Li S, Song X, Jia Y, Zeng R, Wu D, Pan W, Hao X, Li L: Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/β-catenin transcriptional activity. Cell Discov. 2017; 2017 Jan 31. PMID: 28417011

Nishi A, Matamales M, Musante V, Valjent E, Kuroiwa M, Kitahara Y, Rebholz H, Greengard P, Girault JA, Nairn AC: Glutamate Counteracts Dopamine/PKA Signaling via Dephosphorylation of DARPP-32 Ser-97 and Alteration of Its Cytonuclear Distribution. J Biol Chem. 2017 Jan 27; 2016 Dec 20. PMID: 27998980

Metheetrairut C, Adams BD, Nallur S, Weidhaas JB, Slack FJ: cel-mir-237 and its homologue, hsa-miR-125b, modulate the cellular response to ionizing radiation. Oncogene. 2017 Jan 26; 2016 Jun 20. PMID: 27321180

Goldberg AB, Cho E, Miller CJ, Lou HJ, Turk BE: Identification of a Substrate-selective Exosite within the Metalloproteinase Anthrax Lethal Factor. J Biol Chem. 2017 Jan 20; 2016 Dec 1. PMID: 27909054

Harkany T, Horvath TL: (S)Pot on Mitochondria: Cannabinoids Disrupt Cellular Respiration to Limit Neuronal Activity. Cell Metab. 2017 Jan 10. PMID: 28076767

Xiong Y, Liu T, Wang S, Chi H, Chen C, Zheng J: Cyclophosphamide promotes the proliferation inhibition of mouse ovarian granulosa cells and premature ovarian failure by activating the lncRNA-Meg3-p53-p66Shc pathway. Gene. 2017 Jan 5; 2016 Oct 10. PMID: 27729272

Hong F, Mohammad Rachidi S, Lundgren D, Han D, Huang X, Zhao H, Kimura Y, Hirano H, Ohara O, Udono H, Meng S, Liu B, Li Z: Mapping the Interactome of a Major Mammalian Endoplasmic Reticulum Heat Shock Protein 90. PLoS One. 2017; 2017 Jan 5. PMID: 28056051

Ghosal S, Packard AEB, Mahbod P, McKlveen JM, Seeley RJ, Myers B, Ulrich-Lai Y, Smith EP, D'Alessio DA, Herman JP: Disruption of Glucagon-Like Peptide 1 Signaling in Sim1 Neurons Reduces Physiological and Behavioral Reactivity to Acute and Chronic Stress. J Neurosci. 2017 Jan 4. PMID: 28053040

Chen C, Chen H, Zhou HJ, Ji W, Min W: Mechanistic Role of Thioredoxin 2 in Heart Failure. Adv Exp Med Biol. 2017. PMID: 28551792

Li M, Soroka CJ, Harry K, Boyer JL: CFTR-associated ligand is a negative regulator of Mrp2 expression. Am J Physiol Cell Physiol. 2017 Jan 1; 2016 Nov 9. PMID: 27834195

Gauthier AC, Liu J: Epigenetics and Signaling Pathways in Glaucoma. Biomed Res Int. 2017; 2017 Jan 22. PMID: 28210622

Vonhoff F, Keshishian H: Cyclic nucleotide signaling is required during synaptic refinement at the Drosophila neuromuscular junction. Dev Neurobiol. 2017 Jan; 2016 Jun 20. PMID: 27281494

Ke S, Chen S, Dong Z, Hong CS, Zhang Q, Tang L, Yang P, Zhai J, Yan H, Shen F, Zhuang Z, Wen W, Wang H: Erythrocytosis in hepatocellular carcinoma portends poor prognosis by respiratory dysfunction secondary to mitochondrial DNA mutations. Hepatology. 2017 Jan; 2016 Nov 25. PMID: 27774607

Singh AK, Pantouris G, Borosch S, Rojanasthien S, Cho TY: Structural basis for decreased induction of class IB PI3-kinases expression by MIF inhibitors. J Cell Mol Med. 2017 Jan; 2016 Sep 13. PMID: 27619729

Wang M, Collins MJ, Foster TR, Bai H, Hashimoto T, Santana JM, Shu C, Dardik A: Eph-B4 mediates vein graft adaptation by regulation of endothelial nitric oxide synthase. J Vasc Surg. 2017 Jan; 2016 Jan 24. PMID: 26817610

Barber KW, Rinehart J: Expression of Recombinant Phosphoproteins for Signal Transduction Studies. Methods Mol Biol. 2017. PMID: 28730473

Liu J, Hua R, Gong Z, Shang B, Huang Y, Guo L, Liu T, Xue J: Human amniotic epithelial cells inhibit CD4+ T cell activation in acute kidney injury patients by influencing the miR-101-c-Rel-IL-2 pathway. Mol Immunol. 2017 Jan; 2016 Nov 26. PMID: 27898347

Marte A, Messa M, Benfenati F, Onofri F: Synapsins Are Downstream Players of the BDNF-Mediated Axonal Growth. Mol Neurobiol. 2017 Jan; 2016 Jan 7. PMID: 26742525

Corti F, Simons M: Modulation of VEGF receptor 2 signaling by protein phosphatases. Pharmacol Res. 2017 Jan; 2016 Nov 23. PMID: 27888154

Kaczmarek LK, Aldrich RW, Chandy KG, Grissmer S, Wei AD, Wulff H: International Union of Basic and Clinical Pharmacology. C. Nomenclature and Properties of Calcium-Activated and Sodium-Activated Potassium Channels. Pharmacol Rev. 2017 Jan; 2016 Nov 15. PMID: 28267675

Keysar SB, Le PN, Miller B, Jackson BC, Eagles JR, Nieto C, Kim J, Tang B, Glogowska MJ, Morton JJ, Padilla-Just N, Gomez K, Warnock E, Reisinger J, Arcaroli JJ, Messersmith WA, Wakefield LM, Gao D, Tan AC, Serracino H, Vasiliou V, Roop DR, Wang XJ, Jimeno A: Regulation of Head and Neck Squamous Cancer Stem Cells by PI3K and SOX2. J Natl Cancer Inst. 2017 Jan; 2016 Sep 15. PMID: 27634934

Cockerill PN: Receptor Signaling Directs Global Recruitment of Pre-existing Transcription Factors to Inducible Elements. Yale J Biol Med. 2016 Dec; 2016 Dec 23. PMID: 28018147

Savage AF, Kolev NG, Franklin JB, Vigneron A, Aksoy S, Tschudi C: Transcriptome Profiling of Trypanosoma brucei Development in the Tsetse Fly Vector Glossina morsitans. PLoS One. 2016; 2016 Dec 21. PMID: 28002435

Davoli T, Mengwasser KE, Duan J, Chen T, Christensen C, Wooten EC, Anselmo AN, Li MZ, Wong KK, Kahle KT, Elledge SJ: Functional genomics reveals that tumors with activating phosphoinositide 3-kinase mutations are dependent on accelerated protein turnover. Genes Dev. 2016 Dec 15. PMID: 28087713

Sasaki CT, Toman J, Vageli D: The In Vitro Effect of Acidic-Pepsin on Nuclear Factor KappaB Activation and Its Related Oncogenic Effect on Normal Human Hypopharyngeal Cells. PLoS One. 2016; 2016 Dec 14. PMID: 27973541

Dhodapkar MV: MGUS to myeloma: a mysterious gammopathy of underexplored significance. Blood. 2016 Dec 8; 2016 Oct 13. PMID: 27737890

He F, Chen H, Yang P, Wu Q, Zhang T, Wang C, Wei J, Chen Z, Hu H, Li W, Cao J: Gankyrin sustains PI3K/GSK-3β/β-catenin signal activation and promotes colorectal cancer aggressiveness and progression. Oncotarget. 2016 Dec 6. PMID: 27835604

Yoo SA, Leng L, Kim BJ, Du X, Tilstam PV, Kim KH, Kong JS, Yoon HJ, Liu A, Wang T, Song Y, Sauler M, Bernhagen J, Ritchlin CT, Lee P, Cho CS, Kim WU, Bucala R: MIF allele-dependent regulation of the MIF coreceptor CD44 and role in rheumatoid arthritis. Proc Natl Acad Sci U S A. 2016 Dec 6; 2016 Nov 21. PMID: 27872288

Shi H, Shen X, Liu R, Xue C, Wei N, Deng XW, Zhong S: The Red Light Receptor Phytochrome B Directly Enhances Substrate-E3 Ligase Interactions to Attenuate Ethylene Responses. Dev Cell. 2016 Dec 5; 2016 Nov 23. PMID: 27889482

Rivera-Gonzalez GC, Shook BA, Andrae J, Holtrup B, Bollag K, Betsholtz C, Rodeheffer MS, Horsley V: Skin Adipocyte Stem Cell Self-Renewal Is Regulated by a PDGFA/AKT-Signaling Axis. Cell Stem Cell. 2016 Dec 1; 2016 Oct 13. PMID: 27746098

de Lartigue G, Diepenbroek C: Novel developments in vagal afferent nutrient sensing and its role in energy homeostasis. Curr Opin Pharmacol. 2016 Dec; 2016 Sep 2. PMID: 27591963

Munro ML, Jayasinghe ID, Wang Q, Quick A, Wang W, Baddeley D, Wehrens XH, Soeller C: Junctophilin-2 in the nanoscale organisation and functional signalling of ryanodine receptor clusters in cardiomyocytes. J Cell Sci. 2016 Dec 1; 2016 Oct 21. PMID: 27802169

Nascimento MS, Ferreira MD, Quirino GF, Maruyama SR, Krishnaswamy JK, Liu D, Berlink J, Fonseca DM, Zamboni DS, Carregaro V, Almeida RP, Cunha TM, Eisenbarth SS, Silva JS: NOD2-RIP2-Mediated Signaling Helps Shape Adaptive Immunity in Visceral Leishmaniasis. J Infect Dis. 2016 Dec 1; 2016 Sep 20. PMID: 27651416

Glerup S, Bolcho U, Mølgaard S, Bøggild S, Vaegter CB, Smith AH, Nieto-Gonzalez JL, Ovesen PL, Pedersen LF, Fjorback AN, Kjolby M, Login H, Holm MM, Andersen OM, Nyengaard JR, Willnow TE, Jensen K, Nykjaer A: SorCS2 is required for BDNF-dependent plasticity in the hippocampus. Mol Psychiatry. 2016 Dec; 2016 Jul 26. PMID: 27457814

Lepack AE, Bang E, Lee B, Dwyer JM, Duman RS: Fast-acting antidepressants rapidly stimulate ERK signaling and BDNF release in primary neuronal cultures. Neuropharmacology. 2016 Dec; 2016 Sep 12. PMID: 27634096

Ghoochani A, Schwarz MA, Yakubov E, Engelhorn T, Doerfler A, Buchfelder M, Bucala R, Savaskan NE, Eyüpoglu IY: MIF-CD74 signaling impedes microglial M1 polarization and facilitates brain tumorigenesis. Oncogene. 2016 Dec 1; 2016 May 9. PMID: 27157615

Filippova EV, Wawrzak Z, Ruan J, Pshenychnyi S, Schultz RM, Wolfe AJ, Anderson WF: Crystal structure of nonphosphorylated receiver domain of the stress response regulator RcsB from Escherichia coli. Protein Sci. 2016 Dec; 2016 Oct 24. PMID: 27670836

Chen X, Tzekov R, Su M, Hong H, Min W, Han A, Li W: Auranofin Inhibits Retinal Pigment Epithelium Cell Survival through Reactive Oxygen Species-Dependent Epidermal Growth Factor Receptor/ Mitogen-Activated Protein Kinase Signaling Pathway. PLoS One. 2016; 2016 Nov 15. PMID: 27846303

Pena-Philippides JC, Caballero-Garrido E, Lordkipanidze T, Roitbak T: In vivo inhibition of miR-155 significantly alters post-stroke inflammatory response. J Neuroinflammation. 2016 Nov 9; 2016 Nov 9. PMID: 27829437

Ishizawa K, Xu N, Loffing J, Lifton RP, Fujita T, Uchida S, Shibata S: Potassium depletion stimulates Na-Cl cotransporter via phosphorylation and inactivation of the ubiquitin ligase Kelch-like 3. Biochem Biophys Res Commun. 2016 Nov; 2016 Oct 29. PMID: 27942049

Hedl M, Abraham C: A TPL2 (MAP3K8) disease-risk polymorphism increases TPL2 expression thereby leading to increased pattern recognition receptor-initiated caspase-1 and caspase-8 activation, signalling and cytokine secretion. Gut. 2016 Nov; 2015 Jul 27. PMID: 26215868

Hedl M, Proctor DD, Abraham C: JAK2 Disease-Risk Variants Are Gain of Function and JAK Signaling Threshold Determines Innate Receptor-Induced Proinflammatory Cytokine Secretion in Macrophages. J Immunol. 2016 Nov 1; 2016 Sep 23. PMID: 27664279

Kidd M, Modlin I, Öberg K: Towards a new classification of gastroenteropancreatic neuroendocrine neoplasms. Nat Rev Clin Oncol. 2016 Nov; 2016 Jun 7. PMID: 27273044

Lucas CL, Chandra A, Nejentsev S, Condliffe AM, Okkenhaug K: PI3Kδ and primary immunodeficiencies. Nat Rev Immunol. 2016 Nov; 2016 Sep 12. PMID: 27616589

Fröhlich F, Olson DK, Christiano R, Farese RV Jr, Walther TC: Proteomic and phosphoproteomic analyses of yeast reveal the global cellular response to sphingolipid depletion. Proteomics. 2016 Nov. PMID: 27717283

Durning SP, Preston-Hurlburt P, Clark PR, Xu D, Herold KC, Type 1 Diabetes TrialNet Study Group.: The Receptor for Advanced Glycation Endproducts Drives T Cell Survival and Inflammation in Type 1 Diabetes Mellitus. J Immunol. 2016 Oct 15; 2016 Sep 21. PMID: 27655844

Gong J, Belinsky G, Sagheer U, Zhang X, Grippo PJ, Chung C: Pigment Epithelium-derived Factor (PEDF) Blocks Wnt3a Protein-induced Autophagy in Pancreatic Intraepithelial Neoplasms. J Biol Chem. 2016 Oct 14; 2016 Aug 24. PMID: 27557659

Philip NH, DeLaney A, Peterson LW, Santos-Marrero M, Grier JT, Sun Y, Wynosky-Dolfi MA, Zwack EE, Hu B, Olsen TM, Rongvaux A, Pope SD, López CB, Oberst A, Beiting DP, Henao-Mejia J, Brodsky IE: Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death. PLoS Pathog. 2016 Oct; 2016 Oct 13. PMID: 27737018

Sanduja S, Feng Y, Mathis RA, Sokol ES, Reinhardt F, Halaban R, Gupta PB: AMPK promotes tolerance to Ras pathway inhibition by activating autophagy. Oncogene. 2016 Oct 6; 2016 Apr 4. PMID: 27041569

Liddicoat BJ, Hartner JC, Piskol R, Ramaswami G, Chalk AM, Kingsley PD, Sankaran VG, Wall M, Purton LE, Seeburg PH, Palis J, Orkin SH, Lu J, Li JB, Walkley CR: Adenosine-to-inosine RNA editing by ADAR1 is essential for normal murine erythropoiesis. Exp Hematol. 2016 Oct; 2016 Jul 1. PMID: 27373493

Chuang LS, Villaverde N, Hui KY, Mortha A, Rahman A, Levine AP, Haritunians T, Evelyn Ng SM, Zhang W, Hsu NY, Facey JA, Luong T, Fernandez-Hernandez H, Li D, Rivas M, Schiff ER, Gusev A, Schumm LP, Bowen BM, Sharma Y, Ning K, Remark R, Gnjatic S, Legnani P, George J, Sands BE, Stempak JM, Datta LW, Lipka S, Katz S, Cheifetz AS, Barzilai N, Pontikos N, Abraham C, Dubinsky MJ, Targan S, Taylor K, Rotter JI, Scherl EJ, Desnick RJ, Abreu MT, Zhao H, Atzmon G, Pe'er I, Kugathasan S, Hakonarson H, McCauley JL, Lencz T, Darvasi A, Plagnol V, Silverberg MS, Muise AM, Brant SR, Daly MJ, Segal AW, Duerr RH, Merad M, McGovern DP, Peter I, Cho JH: A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF. Gastroenterology. 2016 Oct; 2016 Jul 1. PMID: 27377463

Yun S, Budatha M, Dahlman JE, Coon BG, Cameron RT, Langer R, Anderson DG, Baillie G, Schwartz MA: Interaction between integrin α5 and PDE4D regulates endothelial inflammatory signalling. Nat Cell Biol. 2016 Oct; 2016 Sep 5. PMID: 27595237

Simons M, Gordon E, Claesson-Welsh L: Mechanisms and regulation of endothelial VEGF receptor signalling. Nat Rev Mol Cell Biol. 2016 Oct; 2016 Jul 27. PMID: 27461391

Rapanelli M, Frick LR, Horn KD, Schwarcz RC, Pogorelov V, Nairn AC, Pittenger C: The Histamine H3 Receptor Differentially Modulates Mitogen-activated Protein Kinase (MAPK) and Akt Signaling in Striatonigral and Striatopallidal Neurons. J Biol Chem. 2016 Sep 30; 2016 Aug 10. PMID: 27510032

Baeyens N, Larrivée B, Ola R, Hayward-Piatkowskyi B, Dubrac A, Huang B, Ross TD, Coon BG, Min E, Tsarfati M, Tong H, Eichmann A, Schwartz MA: Defective fluid shear stress mechanotransduction mediates hereditary hemorrhagic telangiectasia. J Cell Biol. 2016 Sep 26; 2016 Sep 19. PMID: 27646277

Greene M, Lai Y, Pajcini K, Bailis W, Pear WS, Lancaster E: Delta/Notch-Like EGF-Related Receptor (DNER) Is Not a Notch Ligand. PLoS One. 2016; 2016 Sep 13. PMID: 27622512

Groisman EA: Feedback Control of Two-Component Regulatory Systems. Annu Rev Microbiol. 2016 Sep 8. PMID: 27607549

Manes TD, Pober JS: Significant Differences in Antigen-Induced Transendothelial Migration of Human CD8 and CD4 T Effector Memory Cells. Arterioscler Thromb Vasc Biol. 2016 Sep; 2016 Jul 21. PMID: 27444200

Lu H, Wang T, Li J, Fedele C, Liu Q, Zhang J, Jiang Z, Jain D, Iozzo RV, Violette SM, Weinreb PH, Davis RJ, Gioeli D, FitzGerald TJ, Altieri DC, Languino LR: αvβ6 Integrin Promotes Castrate-Resistant Prostate Cancer through JNK1-Mediated Activation of Androgen Receptor. Cancer Res. 2016 Sep 1; 2016 Jul 22. PMID: 27450452

Cho S, Mutlu L, Zhou Y, Taylor HS: Aromatase inhibitor regulates let-7 expression and let-7f-induced cell migration in endometrial cells from women with endometriosis. Fertil Steril. 2016 Sep 1; 2016 Jun 16. PMID: 27320036

Mehal W, To U: New approaches for fibrosis regression in alcoholic cirrhosis. Hepatol Int. 2016 Sep; 2016 Jul 26. PMID: 27460408

Halaban R, Krauthammer M: RASopathy Gene Mutations in Melanoma. J Invest Dermatol. 2016 Sep; 2016 May 25. PMID: 27236105

Choi J, Groisman EA: Acidic pH sensing in the bacterial cytoplasm is required for Salmonella virulence. Mol Microbiol. 2016 Sep; 2016 Jul 8. PMID: 27282333

Gerhold KA, Schwartz MA: Ion Channels in Endothelial Responses to Fluid Shear Stress. Physiology (Bethesda). 2016 Sep. PMID: 27511462

Chowen JA, Argente-Arizón P, Freire-Regatillo A, Frago LM, Horvath TL, Argente J: The role of astrocytes in the hypothalamic response and adaptation to metabolic signals. Prog Neurobiol. 2016 Sep; 2016 Mar 18. PMID: 27000556

Zou S, Teixeira AM, Yin M, Xiang Y, Xavier-Ferrucio J, Zhang PX, Hwa J, Min W, Krause DS: Leukaemia-associated Rho guanine nucleotide exchange factor (LARG) plays an agonist specific role in platelet function through RhoA activation. Thromb Haemost. 2016 Aug 30; 2016 Jun 23. PMID: 27345948

Kin K, Maziarz J, Chavan AR, Kamat M, Vasudevan S, Birt A, Emera D, Lynch VJ, Ott TL, Pavlicev M, Wagner GP: The Transcriptomic Evolution of Mammalian Pregnancy: Gene Expression Innovations in Endometrial Stromal Fibroblasts. Genome Biol Evol. 2016 Aug 25; 2016 Aug 25. PMID: 27401177

Wang K, Langevin S, O'Hern CS, Shattuck MD, Ogle S, Forero A, Morrison J, Slayden R, Katze MG, Kirby M: Anomaly Detection in Host Signaling Pathways for the Early Prognosis of Acute Infection. PLoS One. 2016; 2016 Aug 17. PMID: 27532264

Wetzel DM, Rhodes EL, Li S, McMahon-Pratt D, Koleske AJ: The Src kinases Hck, Fgr and Lyn activate Arg to facilitate IgG-mediated phagocytosis and Leishmania infection. J Cell Sci. 2016 Aug 15; 2016 Jun 29. PMID: 27358479

García-Cáceres C, Quarta C, Varela L, Gao Y, Gruber T, Legutko B, Jastroch M, Johansson P, Ninkovic J, Yi CX, Le Thuc O, Szigeti-Buck K, Cai W, Meyer CW, Pfluger PT, Fernandez AM, Luquet S, Woods SC, Torres-Alemán I, Kahn CR, Götz M, Horvath TL, Tschöp MH: Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability. Cell. 2016 Aug 11. PMID: 27518562

Lim YH, Bacchiocchi A, Qiu J, Straub R, Bruckner A, Bercovitch L, Narayan D, Yale Center for Mendelian Genomics., McNiff J, Ko C, Robinson-Bostom L, Antaya R, Halaban R, Choate KA: GNA14 Somatic Mutation Causes Congenital and Sporadic Vascular Tumors by MAPK Activation. Am J Hum Genet. 2016 Aug 4; 2016 Jul 28. PMID: 27476652

Aggarwal S, Mannam P, Zhang J: Differential regulation of autophagy and mitophagy in pulmonary diseases. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1; 2016 Jul 8. PMID: 27402690

Kitz A, de Marcken M, Gautron AS, Mitrovic M, Hafler DA, Dominguez-Villar M: AKT isoforms modulate Th1-like Treg generation and function in human autoimmune disease. EMBO Rep. 2016 Aug; 2016 Jun 16. PMID: 27312110

Belinsky GS, Sreekumar B, Andrejecsk JW, Saltzman WM, Gong J, Herzog RI, Lin S, Horsley V, Carpenter TO, Chung C: Pigment epithelium-derived factor restoration increases bone mass and improves bone plasticity in a model of osteogenesis imperfecta type VI via Wnt3a blockade. FASEB J. 2016 Aug; 2016 Apr 28. PMID: 27127101

Malu K, Garhwal R, Pelletier MG, Gotur D, Halene S, Zwerger M, Yang ZF, Rosmarin AG, Gaines P: Cooperative Activity of GABP with PU.1 or C/EBPε Regulates Lamin B Receptor Gene Expression, Implicating Their Roles in Granulocyte Nuclear Maturation. J Immunol. 2016 Aug 1; 2016 Jun 24. PMID: 27342846

Jeon BT, Heo RW, Jeong EA, Yi CO, Lee JY, Kim KE, Kim H, Roh GS: Effects of caloric restriction on O-GlcNAcylation, Ca(2+) signaling, and learning impairment in the hippocampus of ob/ob mice. Neurobiol Aging. 2016 Aug; 2016 May 10. PMID: 27318140

Juvekar A, Hu H, Yadegarynia S, Lyssiotis CA, Ullas S, Lien EC, Bellinger G, Son J, Hok RC, Seth P, Daly MB, Kim B, Scully R, Asara JM, Cantley LC, Wulf GM: Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion. Proc Natl Acad Sci U S A. 2016 Jul 26; 2016 Jul 8. PMID: 27402769

Rich MT, Abbott TB, Chung L, Gulcicek EE, Stone KL, Colangelo CM, Lam TT, Nairn AC, Taylor JR, Torregrossa MM: Phosphoproteomic Analysis Reveals a Novel Mechanism of CaMKIIα Regulation Inversely Induced by Cocaine Memory Extinction versus Reconsolidation. J Neurosci. 2016 Jul 20. PMID: 27445140

Dunn NR, Tolwinski NS: Ptk7 and Mcc, Unfancied Components in Non-Canonical Wnt Signaling and Cancer. Cancers (Basel). 2016 Jul 16; 2016 Jul 16. PMID: 27438854

Pfaff MJ, Xue K, Li L, Horowitz MC, Steinbacher DM, Eswarakumar JVP: FGFR2c-mediated ERK-MAPK activity regulates coronal suture development. Dev Biol. 2016 Jul 15; 2016 Mar 28. PMID: 27034231

Gao Y, Yin Y, Xing X, Zhao Z, Lu Y, Sun Y, Zhuang Z, Wang M, Ji W, He Y: Arsenic-induced anti-angiogenesis via miR-425-5p-regulated CCM3. Toxicol Lett. 2016 Jul 8; 2016 Apr 27. PMID: 27132035

Covino R, Ballweg S, Stordeur C, Michaelis JB, Puth K, Wernig F, Bahrami A, Ernst AM, Hummer G, Ernst R: A Eukaryotic Sensor for Membrane Lipid Saturation. Mol Cell. 2016 Jul 7; 2016 Jun 16. PMID: 27320200

Kravtsov DV, Ahsan MK, Kumari V, van Ijzendoorn SC, Reyes-Mugica M, Kumar A, Gujral T, Dudeja PK, Ameen NA: Identification of intestinal ion transport defects in microvillus inclusion disease. Am J Physiol Gastrointest Liver Physiol. 2016 Jul 1; 2016 May 26. PMID: 27229121

Hollander L, Guo X, Velazquez H, Chang J, Safirstein R, Kluger H, Cha C, Desir GV: Renalase Expression by Melanoma and Tumor-Associated Macrophages Promotes Tumor Growth through a STAT3-Mediated Mechanism. Cancer Res. 2016 Jul 1; 2016 May 9. PMID: 27197188

Damsky WE, Choi J: Genetics of Cutaneous T Cell Lymphoma: From Bench to Bedside. Curr Treat Options Oncol. 2016 Jul. PMID: 27262707

Giordano FJ, Wang Y, Desir GV: A Remote Role for Renalase. EBioMedicine. 2016 Jul; 2016 Jun 25. PMID: 27374133

Lee SH, Du J, Stitham J, Atteya G, Lee S, Xiang Y, Wang D, Jin Y, Leslie KL, Spollett G, Srivastava A, Mannam P, Ostriker A, Martin KA, Tang WH, Hwa J: Inducing mitophagy in diabetic platelets protects against severe oxidative stress. EMBO Mol Med. 2016 Jul; 2016 Jul 1. PMID: 27221050

Chen PY, Qin L, Li G, Tellides G, Simons M: Smooth muscle FGF/TGFβ cross talk regulates atherosclerosis progression. EMBO Mol Med. 2016 Jul; 2016 Jul 1. PMID: 27189169

Tai N, Wong FS, Wen L: The role of the innate immune system in destruction of pancreatic beta cells in NOD mice and humans with type I diabetes. J Autoimmun. 2016 Jul; 2016 Mar 24. PMID: 27021275

Al-Lamki RS, Lu W, Manalo P, Wang J, Warren AY, Tolkovsky AM, Pober JS, Bradley JR: Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis. Cell Death Dis. 2016 Jun 30; 2016 Jun 30. PMID: 27362805

Raina K, Lu J, Qian Y, Altieri M, Gordon D, Rossi AM, Wang J, Chen X, Dong H, Siu K, Winkler JD, Crew AP, Crews CM, Coleman KG: PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016 Jun 28; 2016 Jun 6. PMID: 27274052

Lv C, Stewart WJ, Akanyeti O, Frederick C, Zhu J, Santos-Sacchi J, Sheets L, Liao JC, Zenisek D: Synaptic Ribbons Require Ribeye for Electron Density, Proper Synaptic Localization, and Recruitment of Calcium Channels. Cell Rep. 2016 Jun 21; 2016 Jun 9. PMID: 27292637

Boccitto M, Doshi S, Newton IP, Nathke I, Neve R, Dong F, Mao Y, Zhai J, Zhang L, Kalb R: Opposing actions of the synapse-associated protein of 97-kDa molecular weight (SAP97) and Disrupted in Schizophrenia 1 (DISC1) on Wnt/β-catenin signaling. Neuroscience. 2016 Jun 21; 2016 Mar 26. PMID: 27026592

Zhang Y, Shan P, Srivastava A, Jiang G, Zhang X, Lee PJ: An Endothelial Hsp70-TLR4 Axis Limits Nox3 Expression and Protects Against Oxidant Injury in Lungs. Antioxid Redox Signal. 2016 Jun 10; 2016 Apr 22. PMID: 26905942

Dutheil S, Watabe I, Sadlaoud K, Tonetto A, Tighilet B: BDNF Signaling Promotes Vestibular Compensation by Increasing Neurogenesis and Remodeling the Expression of Potassium-Chloride Cotransporter KCC2 and GABAA Receptor in the Vestibular Nuclei. J Neurosci. 2016 Jun 8. PMID: 27277799

Santos-Sacchi J, Song L: Chloride Anions Regulate Kinetics but Not Voltage-Sensor Qmax of the Solute Carrier SLC26a5. Biophys J. 2016 Jun 7. PMID: 27276272

Mortensen LS, Park SJH, Ke JB, Cooper BH, Zhang L, Imig C, Löwel S, Reim K, Brose N, Demb JB, Rhee JS, Singer JH: Complexin 3 Increases the Fidelity of Signaling in a Retinal Circuit by Regulating Exocytosis at Ribbon Synapses. Cell Rep. 2016 Jun 7; 2016 May 26. PMID: 27239031

Madeo M, Stewart M, Sun Y, Sahir N, Wiethoff S, Chandrasekar I, Yarrow A, Rosenfeld JA, Yang Y, Cordeiro D, McCormick EM, Muraresku CC, Jepperson TN, McBeth LJ, Seidahmed MZ, El Khashab HY, Hamad M, Azzedine H, Clark K, Corrochano S, Wells S, Elting MW, Weiss MM, Burn S, Myers A, Landsverk M, Crotwell PL, Waisfisz Q, Wolf NI, Nolan PM, Padilla-Lopez S, Houlden H, Lifton R, Mane S, Singh BB, Falk MJ, Mercimek-Mahmutoglu S, Bilguvar K, Salih MA, Acevedo-Arozena A, Kruer MC: Loss-of-Function Mutations in FRRS1L Lead to an Epileptic-Dyskinetic Encephalopathy. Am J Hum Genet. 2016 Jun 2; 2016 May 26. PMID: 27236917

Hwang SS, Kim LK, Lee GR, Flavell RA: Role of OCT-1 and partner proteins in T cell differentiation. Biochim Biophys Acta. 2016 Jun; 2016 Apr 26. PMID: 27126747

Vazirani RP, Verma A, Sadacca LA, Buckman MS, Picatoste B, Beg M, Torsitano C, Bruno JH, Patel RT, Simonyte K, Camporez JP, Moreira G, Falcone DJ, Accili D, Elemento O, Shulman GI, Kahn BB, McGraw TE: Disruption of Adipose Rab10-Dependent Insulin Signaling Causes Hepatic Insulin Resistance. Diabetes. 2016 Jun; 2016 Mar 25. PMID: 27207531

Lee N, Shin MS, Kang Y, Park K, Maeda T, Nishioka H, Fujii H, Kang I: Oligonol, a lychee fruit-derived low-molecular form of polyphenol mixture, suppresses inflammatory cytokine production from human monocytes. Hum Immunol. 2016 Jun; 2016 Apr 11. PMID: 27079270

Stahl M, Gedrich R, Peck R, LaVallee T, Eder JP: Targeting KIT on innate immune cells to enhance the antitumor activity of checkpoint inhibitors. Immunotherapy. 2016 Jun. PMID: 27349976

Mathur PS, Gierut JJ, Guzman G, Xie H, Xicola RM, Llor X, Chastkofsky MI, Perekatt AO, Tyner AL: Kinase-Dependent and -Independent Roles for PTK6 in Colon Cancer. Mol Cancer Res. 2016 Jun; 2016 Mar 16. PMID: 26983689

Alvero AB, Heaton A, Lima E, Pitruzzello M, Sumi N, Yang-Hartwich Y, Cardenas C, Steinmacher S, Silasi DA, Brown D, Mor G: TRX-E-002-1 Induces c-Jun-Dependent Apoptosis in Ovarian Cancer Stem Cells and Prevents Recurrence In Vivo. Mol Cancer Ther. 2016 Jun; 2016 Apr 8. PMID: 27196760

Alexander-Bloch AF, McDougle CJ, Ullman Z, Sweetser DA: IQSEC2 and X-linked syndromal intellectual disability. Psychiatr Genet. 2016 Jun. PMID: 27010919

Tinoco R, Carrette F, Barraza ML, Otero DC, Magaña J, Bosenberg MW, Swain SL, Bradley LM: PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion. Immunity. 2016 May 17. PMID: 27192578

Zhang YW, Turk BE, Rudnick G: Control of serotonin transporter phosphorylation by conformational state. Proc Natl Acad Sci U S A. 2016 May 17; 2016 May 2. PMID: 27140629

Xu Y, Nan D, Fan J, Bogan JS, Toomre D: Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action. J Cell Sci. 2016 May 15; 2016 Apr 13. PMID: 27076519

Wang Z, Liu N, Shi S, Liu S, Lin H: The Role of PIWIL4, an Argonaute Family Protein, in Breast Cancer. J Biol Chem. 2016 May 13; 2016 Mar 8. PMID: 26957540

Uzun A, Schuster J, McGonnigal B, Schorl C, Dewan A, Padbury J: Targeted Sequencing and Meta-Analysis of Preterm Birth. PLoS One. 2016; 2016 May 10. PMID: 27163930

Kumar A, Ouyang M, Van den Dries K, McGhee EJ, Tanaka K, Anderson MD, Groisman A, Goult BT, Anderson KI, Schwartz MA: Talin tension sensor reveals novel features of focal adhesion force transmission and mechanosensitivity. J Cell Biol. 2016 May 9. PMID: 27161398

Yang E, Tacchelly-Benites O, Wang Z, Randall MP, Tian A, Benchabane H, Freemantle S, Pikielny C, Tolwinski NS, Lee E, Ahmed Y: Wnt pathway activation by ADP-ribosylation. Nat Commun. 2016 May 3; 2016 May 3. PMID: 27138857

Brownstein CA, Kleiman RJ, Engle EC, Towne MC, D'Angelo EJ, Yu TW, Beggs AH, Picker J, Fogler JM, Carroll D, Schmitt RC, Wolff RR, Shen Y, Lip V, Bilguvar K, Kim A, Tembulkar S, O'Donnell K, Gonzalez-Heydrich J: Overlapping 16p13.11 deletion and gain of copies variations associated with childhood onset psychosis include genes with mechanistic implications for autism associated pathways: Two case reports. Am J Med Genet A. 2016 May; 2016 Feb 16. PMID: 26887912

Li M, Piao L, Chen CP, Wu X, Yeh CC, Masch R, Chang CC, Huang SJ: Modulation of Decidual Macrophage Polarization by Macrophage Colony-Stimulating Factor Derived from First-Trimester Decidual Cells: Implication in Preeclampsia. Am J Pathol. 2016 May; 2016 Mar 10. PMID: 26970370

Li X, Jung JJ, Nie L, Razavian M, Zhang J, Samuel V, Sadeghi MM: The neuropilin-like protein ESDN regulates insulin signaling and sensitivity. Am J Physiol Heart Circ Physiol. 2016 May 1; 2016 Feb 26. PMID: 26921437

Kofler N, Simons M: The expanding role of neuropilin: regulation of transforming growth factor-β and platelet-derived growth factor signaling in the vasculature. Curr Opin Hematol. 2016 May. PMID: 26849476

Pauta M, Rotllan N, Fernández-Hernando A, Langhi C, Ribera J, Lu M, Boix L, Bruix J, Jimenez W, Suárez Y, Ford DA, Baldán A, Birnbaum MJ, Morales-Ruiz M, Fernández-Hernando C: Akt-mediated foxo1 inhibition is required for liver regeneration. Hepatology. 2016 May; 2015 Dec 18. PMID: 26473496

Kim BH, Chee JD, Bradfield CJ, Park ES, Kumar P, MacMicking JD: Interferon-induced guanylate-binding proteins in inflammasome activation and host defense. Nat Immunol. 2016 May. PMID: 27092805

Braza F, Brouard S, Chadban S, Goldstein DR: Role of TLRs and DAMPs in allograft inflammation and transplant outcomes. Nat Rev Nephrol. 2016 May; 2016 Mar 30. PMID: 27026348

Mineur YS, Fote GM, Blakeman S, Cahuzac EL, Newbold SA, Picciotto MR: Multiple Nicotinic Acetylcholine Receptor Subtypes in the Mouse Amygdala Regulate Affective Behaviors and Response to Social Stress. Neuropsychopharmacology. 2016 May; 2015 Oct 16. PMID: 26471256

Schneider ER, Gracheva EO, Bagriantsev SN: Evolutionary Specialization of Tactile Perception in Vertebrates. Physiology (Bethesda). 2016 May. PMID: 27053733

Miller MR, Mannowetz N, Iavarone AT, Safavi R, Gracheva EO, Smith JF, Hill RZ, Bautista DM, Kirichok Y, Lishko PV: Unconventional endocannabinoid signaling governs sperm activation via the sex hormone progesterone. Science. 2016 Apr 29; 2016 Mar 17. PMID: 26989199

Zhong ZF, Tan W, Qiang WW, Scofield VL, Tian K, Wang CM, Qiang WA, Wang YT: Furanodiene alters mitochondrial function in doxorubicin-resistant MCF-7 human breast cancer cells in an AMPK-dependent manner. Mol Biosyst. 2016 Apr 26. PMID: 26987443

Nilsson MB, Giri U, Gudikote J, Tang X, Lu W, Tran H, Fan Y, Koo A, Diao L, Tong P, Wang J, Herbst R, Johnson BE, Ryan A, Webster A, Rowe P, Wistuba II, Heymach JV: KDR Amplification Is Associated with VEGF-Induced Activation of the mTOR and Invasion Pathways but does not Predict Clinical Benefit to the VEGFR TKI Vandetanib. Clin Cancer Res. 2016 Apr 15; 2015 Nov 17. PMID: 26578684

Kuo IY, Duong SL, Nguyen L, Ehrlich BE: Decreased Polycystin 2 Levels Result in Non-Renal Cardiac Dysfunction with Aging. PLoS One. 2016; 2016 Apr 15. PMID: 27081851

Fourgeaud L, Través PG, Tufail Y, Leal-Bailey H, Lew ED, Burrola PG, Callaway P, Zagórska A, Rothlin CV, Nimmerjahn A, Lemke G: TAM receptors regulate multiple features of microglial physiology. Nature. 2016 Apr 14; 2016 Apr 6. PMID: 27049947

Kaur A, Webster MR, Marchbank K, Behera R, Ndoye A, Kugel CH 3rd, Dang VM, Appleton J, O'Connell MP, Cheng P, Valiga AA, Morissette R, McDonnell NB, Ferrucci L, Kossenkov AV, Meeth K, Tang HY, Yin X, Wood WH 3rd, Lehrmann E, Becker KG, Flaherty KT, Frederick DT, Wargo JA, Cooper ZA, Tetzlaff MT, Hudgens C, Aird KM, Zhang R, Xu X, Liu Q, Bartlett E, Karakousis G, Eroglu Z, Lo RS, Chan M, Menzies AM, Long GV, Johnson DB, Sosman J, Schilling B, Schadendorf D, Speicher DW, Bosenberg M, Ribas A, Weeraratna AT: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance. Nature. 2016 Apr 14; 2016 Apr 4. PMID: 27042933

Balko JM, Schwarz LJ, Luo N, Estrada MV, Giltnane JM, Dávila-González D, Wang K, Sánchez V, Dean PT, Combs SE, Hicks D, Pinto JA, Landis MD, Doimi FD, Yelensky R, Miller VA, Stephens PJ, Rimm DL, Gómez H, Chang JC, Sanders ME, Cook RS, Arteaga CL: Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence. Sci Transl Med. 2016 Apr 13. PMID: 27075627

Shen Y, Ng LF, Low NP, Hagen T, Gruber J, Inoue T: C. elegans miro-1 Mutation Reduces the Amount of Mitochondria and Extends Life Span. PLoS One. 2016; 2016 Apr 11. PMID: 27064409

Liu Z, Sneve M, Haroldson TA, Smith JP, Drewes LR: Regulation of Monocarboxylic Acid Transporter 1 Trafficking by the Canonical Wnt/β-Catenin Pathway in Rat Brain Endothelial Cells Requires Cross-talk with Notch Signaling. J Biol Chem. 2016 Apr 8; 2016 Feb 12. PMID: 26872974

Kamanova J, Sun H, Lara-Tejero M, Galán JE: The Salmonella Effector Protein SopA Modulates Innate Immune Responses by Targeting TRIM E3 Ligase Family Members. PLoS Pathog. 2016 Apr; 2016 Apr 8. PMID: 27058235

Zhang Y, Zhang XF, Fleming MR, Amiri A, El-Hassar L, Surguchev AA, Hyland C, Jenkins DP, Desai R, Brown MR, Gazula VR, Waters MF, Large CH, Horvath TL, Navaratnam D, Vaccarino FM, Forscher P, Kaczmarek LK: Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating. Cell. 2016 Apr 7; 2016 Mar 17. PMID: 26997484

Tan JL, Fogley RD, Flynn RA, Ablain J, Yang S, Saint-André V, Fan ZP, Do BT, Laga AC, Fujinaga K, Santoriello C, Greer CB, Kim YJ, Clohessy JG, Bothmer A, Pandell N, Avagyan S, Brogie JE, van Rooijen E, Hagedorn EJ, Shyh-Chang N, White RM, Price DH, Pandolfi PP, Peterlin BM, Zhou Y, Kim TH, Asara JM, Chang HY, Young RA, Zon LI: Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. Mol Cell. 2016 Apr 7. PMID: 27058786

Lee S, Zhang Y, Chen M, Zhou ZJ: Segregated Glycine-Glutamate Co-transmission from vGluT3 Amacrine Cells to Contrast-Suppressed and Contrast-Enhanced Retinal Circuits. Neuron. 2016 Apr 6; 2016 Mar 17. PMID: 26996083

Park SA, Lee JW, Herbst RS, Koo JS: GSK-3α Is a Novel Target of CREB and CREB-GSK-3α Signaling Participates in Cell Viability in Lung Cancer. PLoS One. 2016; 2016 Apr 6. PMID: 27049759

Huang C, Yuan P, Wu J, Huang J: Estrogen regulates excitatory amino acid carrier 1 (EAAC1) expression through sphingosine kinase 1 (SphK1) transacting FGFR-mediated ERK signaling in rat C6 astroglial cells. Neuroscience. 2016 Apr 5; 2016 Jan 22. PMID: 26804240

Malki K, Tosto MG, Pain O, Sluyter F, Mineur YS, Crusio WE, de Boer S, Sandnabba KN, Kesserwani J, Robinson E, Schalkwyk LC, Asherson P: Comparative mRNA analysis of behavioral and genetic mouse models of aggression. Am J Med Genet B Neuropsychiatr Genet. 2016 Apr; 2016 Feb 17. PMID: 26888158

Zhang D, Lee H, Cao Y, Dela Cruz CS, Jin Y: miR-185 mediates lung epithelial cell death after oxidative stress. Am J Physiol Lung Cell Mol Physiol. 2016 Apr 1; 2016 Jan 8. PMID: 26747785

Schwartz GK, Dickson MA, LoRusso PM, Sausville EA, Maekawa Y, Watanabe Y, Kashima N, Nakashima D, Akinaga S: Preclinical and first-in-human phase I studies of KW-2450, an oral tyrosine kinase inhibitor with insulin-like growth factor receptor-1/insulin receptor selectivity. Cancer Sci. 2016 Apr; 2016 Mar 28. PMID: 26850678

Gritz E, Hirschi KK: Specification and function of hemogenic endothelium during embryogenesis. Cell Mol Life Sci. 2016 Apr; 2016 Feb 5. PMID: 26849156

Hu R, Hochstrasser M: Recent progress in ubiquitin and ubiquitin-like protein (Ubl) signaling. Cell Res. 2016 Apr. PMID: 27033807

Zhu S, Wang G, Lei X, Flavell RA: Mex3B: a coreceptor to present dsRNA to TLR3. Cell Res. 2016 Apr; 2016 Mar 4. PMID: 26940660

Jhaveri K, Teplinsky E, Silvera D, Valeta-Magara A, Arju R, Giashuddin S, Sarfraz Y, Alexander M, Darvishian F, Levine PH, Hashmi S, Zolfaghari L, Hoffman HJ, Singh B, Goldberg JD, Hochman T, Formenti S, Esteva FJ, Moran MS, Schneider RJ: Hyperactivated mTOR and JAK2/STAT3 Pathways: Molecular Drivers and Potential Therapeutic Targets of Inflammatory and Invasive Ductal Breast Cancers After Neoadjuvant Chemotherapy. Clin Breast Cancer. 2016 Apr; 2015 Dec 1. PMID: 26774497

Gillies J, Hickey CM, Su D, Wu Z, Peng J, Hochstrasser M: SUMO Pathway Modulation of Regulatory Protein Binding at the Ribosomal DNA Locus in Saccharomyces cerevisiae. Genetics. 2016 Apr; 2016 Feb 2. PMID: 26837752

Franco I, Margaria JP, De Santis MC, Ranghino A, Monteyne D, Chiaravalli M, Pema M, Campa CC, Ratto E, Gulluni F, Perez-Morga D, Somlo S, Merlo GR, Boletta A, Hirsch E: Phosphoinositide 3-Kinase-C2α Regulates Polycystin-2 Ciliary Entry and Protects against Kidney Cyst Formation. J Am Soc Nephrol. 2016 Apr; 2015 Aug 13. PMID: 26271513

Meijome TE, Baughman JT, Hooker RA, Cheng YH, Ciovacco WA, Balamohan SM, Srinivasan TL, Chitteti BR, Eleniste PP, Horowitz MC, Srour EF, Bruzzaniti A, Fuchs RK, Kacena MA: C-Mpl Is Expressed on Osteoblasts and Osteoclasts and Is Important in Regulating Skeletal Homeostasis. J Cell Biochem. 2016 Apr; 2015 Oct 6. PMID: 26375403

Meza-Romero R, Benedek G, Leng L, Bucala R, Vandenbark AA: Predicted structure of MIF/CD74 and RTL1000/CD74 complexes. Metab Brain Dis. 2016 Apr; 2016 Feb 6. PMID: 26851955

Xin A, Masson F, Liao Y, Preston S, Guan T, Gloury R, Olshansky M, Lin JX, Li P, Speed TP, Smyth GK, Ernst M, Leonard WJ, Pellegrini M, Kaech SM, Nutt SL, Shi W, Belz GT, Kallies A: A molecular threshold for effector CD8(+) T cell differentiation controlled by transcription factors Blimp-1 and T-bet. Nat Immunol. 2016 Apr; 2016 Mar 7. PMID: 26950239

Darisipudi MN, Knauf F: An update on the role of the inflammasomes in the pathogenesis of kidney diseases. Pediatr Nephrol. 2016 Apr; 2015 Jul 16. PMID: 26178650

Tsou PS, Rabquer BJ, Ohara RA, Stinson WA, Campbell PL, Amin MA, Balogh B, Zakhem G, Renauer PA, Lozier A, Arasu E, Haines GK 3rd, Kahaleh B, Schiopu E, Khanna D, Koch AE: Scleroderma dermal microvascular endothelial cells exhibit defective response to pro-angiogenic chemokines. Rheumatology (Oxford). 2016 Apr; 2015 Dec 24. PMID: 26705326

Kahle KT, Schmouth JF, Lavastre V, Latremoliere A, Zhang J, Andrews N, Omura T, Laganière J, Rochefort D, Hince P, Castonguay G, Gaudet R, Mapplebeck JC, Sotocinal SG, Duan J, Ward C, Khanna AR, Mogil JS, Dion PA, Woolf CJ, Inquimbert P, Rouleau GA: Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition. Sci Signal. 2016 Mar 29; 2016 Mar 29. PMID: 27025876

Cappi C, Brentani H, Lima L, Sanders SJ, Zai G, Diniz BJ, Reis VN, Hounie AG, Conceição do Rosário M, Mariani D, Requena GL, Puga R, Souza-Duran FL, Shavitt RG, Pauls DL, Miguel EC, Fernandez TV: Whole-exome sequencing in obsessive-compulsive disorder identifies rare mutations in immunological and neurodevelopmental pathways. Transl Psychiatry. 2016 Mar 29; 2016 Mar 29. PMID: 27023170

Chen F, Zhang Y, Şenbabaoğlu Y, Ciriello G, Yang L, Reznik E, Shuch B, Micevic G, De Velasco G, Shinbrot E, Noble MS, Lu Y, Covington KR, Xi L, Drummond JA, Muzny D, Kang H, Lee J, Tamboli P, Reuter V, Shelley CS, Kaipparettu BA, Bottaro DP, Godwin AK, Gibbs RA, Getz G, Kucherlapati R, Park PJ, Sander C, Henske EP, Zhou JH, Kwiatkowski DJ, Ho TH, Choueiri TK, Hsieh JJ, Akbani R, Mills GB, Hakimi AA, Wheeler DA, Creighton CJ: Multilevel Genomics-Based Taxonomy of Renal Cell Carcinoma. Cell Rep. 2016 Mar 15; 2016 Mar 3. PMID: 26947078

Loi S, Dushyanthen S, Beavis PA, Salgado R, Denkert C, Savas P, Combs S, Rimm DL, Giltnane JM, Estrada MV, Sánchez V, Sanders ME, Cook RS, Pilkinton MA, Mallal SA, Wang K, Miller VA, Stephens PJ, Yelensky R, Doimi FD, Gómez H, Ryzhov SV, Darcy PK, Arteaga CL, Balko JM: RAS/MAPK Activation Is Associated with Reduced Tumor-Infiltrating Lymphocytes in Triple-Negative Breast Cancer: Therapeutic Cooperation Between MEK and PD-1/PD-L1 Immune Checkpoint Inhibitors. Clin Cancer Res. 2016 Mar 15; 2015 Oct 29. PMID: 26515496

Guo X, Snider WD, Chen B: GSK3β regulates AKT-induced central nervous system axon regeneration via an eIF2Bε-dependent, mTORC1-independent pathway. Elife. 2016 Mar 14; 2016 Mar 14. PMID: 26974342

Guo X, Hollander L, MacPherson D, Wang L, Velazquez H, Chang J, Safirstein R, Cha C, Gorelick F, Desir GV: Inhibition of renalase expression and signaling has antitumor activity in pancreatic cancer. Sci Rep. 2016 Mar 14; 2016 Mar 14. PMID: 26972355

Lemmon MA, Freed DM, Schlessinger J, Kiyatkin A: The Dark Side of Cell Signaling: Positive Roles for Negative Regulators. Cell. 2016 Mar 10. PMID: 26967284

Bayliss JA, Lemus MB, Stark R, Santos VV, Thompson A, Rees DJ, Galic S, Elsworth JD, Kemp BE, Davies JS, Andrews ZB: Ghrelin-AMPK Signaling Mediates the Neuroprotective Effects of Calorie Restriction in Parkinson's Disease. J Neurosci. 2016 Mar 9. PMID: 26961958

Brenner MD, Zhou R, Conway DE, Lanzano L, Gratton E, Schwartz MA, Ha T: Spider Silk Peptide Is a Compact, Linear Nanospring Ideal for Intracellular Tension Sensing. Nano Lett. 2016 Mar 9; 2016 Feb 3. PMID: 26824190

Misra A, Sheikh AQ, Kumar A, Luo J, Zhang J, Hinton RB, Smoot L, Kaplan P, Urban Z, Qyang Y, Tellides G, Greif DM: Integrin β3 inhibition is a therapeutic strategy for supravalvular aortic stenosis. J Exp Med. 2016 Mar 7; 2016 Feb 8. PMID: 26858344

Dong K, Yan Q, Lu M, Wan L, Hu H, Guo J, Boulpaep E, Wang W, Giebisch G, Hebert SC, Wang T: Romk1 Knockout Mice Do Not Produce Bartter Phenotype but Exhibit Impaired K Excretion. J Biol Chem. 2016 Mar 4; 2016 Jan 4. PMID: 26728465

Sun H, Kamanova J, Lara-Tejero M, Galán JE: A Family of Salmonella Type III Secretion Effector Proteins Selectively Targets the NF-κB Signaling Pathway to Preserve Host Homeostasis. PLoS Pathog. 2016 Mar; 2016 Mar 2. PMID: 26933955

Zou W, Wolchok JD, Chen L: PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations. Sci Transl Med. 2016 Mar 2. PMID: 26936508

Liu D, Lei L, Desir M, Huang Y, Cleman J, Jiang W, Fernandez-Hernando C, Di Lorenzo A, Sessa WC, Giordano FJ: Smooth Muscle Hypoxia-Inducible Factor 1α Links Intravascular Pressure and Atherosclerosis--Brief Report. Arterioscler Thromb Vasc Biol. 2016 Mar; 2016 Jan 21. PMID: 26800562

Hashimoto T, Tsuneki M, Foster TR, Santana JM, Bai H, Wang M, Hu H, Hanisch JJ, Dardik A: Membrane-mediated regulation of vascular identity. Birth Defects Res C Embryo Today. 2016 Mar; 2016 Mar 17. PMID: 26992081

Wang J, Ye Z, Zheng S, Chen L, Wan Y, Deng Y, Yang R: Lingo-1 shRNA and Notch signaling inhibitor DAPT promote differentiation of neural stem/progenitor cells into neurons. Brain Res. 2016 Mar 1; 2015 Nov 24. PMID: 26607252

Takyar S, Zhang Y, Haslip M, Jin L, Shan P, Zhang X, Lee PJ: An endothelial TLR4-VEGFR2 pathway mediates lung protection against oxidant-induced injury. FASEB J. 2016 Mar; 2015 Dec 11. PMID: 26655705

Tsuneki M, Madri JA: CD44 Influences Fibroblast Behaviors Via Modulation of Cell-Cell and Cell-Matrix Interactions, Affecting Survivin and Hippo Pathways. J Cell Physiol. 2016 Mar. PMID: 26248063

Wong DJ, Lu DY, Protack CD, Kuwahara G, Bai H, Sadaghianloo N, Tellides G, Dardik A: Ephrin type-B receptor 4 activation reduces neointimal hyperplasia in human saphenous vein in vitro. J Vasc Surg. 2016 Mar; 2014 Oct 24. PMID: 25446283

Coleman BD, Marivin A, Parag-Sharma K, DiGiacomo V, Kim S, Pepper JS, Casler J, Nguyen LT, Koelle MR, Garcia-Marcos M: Evolutionary Conservation of a GPCR-Independent Mechanism of Trimeric G Protein Activation. Mol Biol Evol. 2016 Mar; 2015 Dec 10. PMID: 26659249

Duman RS, Aghajanian GK, Sanacora G, Krystal JH: Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants. Nat Med. 2016 Mar. PMID: 26937618

Babayev E, Lalioti MD, Favero F, Seli E: Cross-Talk Between FSH and Endoplasmic Reticulum Stress: A Mutually Suppressive Relationship. Reprod Sci. 2016 Mar; 2015 Sep 3. PMID: 26342052

Elder JH, Victor J, Zucker SW: Understanding the statistics of the natural environment and their implications for vision. Vision Res. 2016 Mar; 2016 Feb 8. PMID: 26851343

Rash BG, Ackman JB, Rakic P: Bidirectional radial Ca(2+) activity regulates neurogenesis and migration during early cortical column formation. Sci Adv. 2016 Feb; 2016 Feb 26. PMID: 26933693

Vernia S, Morel C, Madara JC, Cavanagh-Kyros J, Barrett T, Chase K, Kennedy NJ, Jung DY, Kim JK, Aronin N, Flavell RA, Lowell BB, Davis RJ: Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress. Elife. 2016 Feb 24; 2016 Feb 24. PMID: 26910012

Spadaro O, Goldberg EL, Camell CD, Youm YH, Kopchick JJ, Nguyen KY, Bartke A, Sun LY, Dixit VD: Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence. Cell Rep. 2016 Feb 23; 2016 Feb 11. PMID: 26876170

Noren DP, Chou WH, Lee SH, Qutub AA, Warmflash A, Wagner DS, Popel AS, Levchenko A: Endothelial cells decode VEGF-mediated Ca2+ signaling patterns to produce distinct functional responses. Sci Signal. 2016 Feb 23; 2016 Feb 23. PMID: 26905425

Chae WJ, Ehrlich AK, Chan PY, Teixeira AM, Henegariu O, Hao L, Shin JH, Park JH, Tang WH, Kim ST, Maher SE, Goldsmith-Pestana K, Shan P, Hwa J, Lee PJ, Krause DS, Rothlin CV, McMahon-Pratt D, Bothwell AL: The Wnt Antagonist Dickkopf-1 Promotes Pathological Type 2 Cell-Mediated Inflammation. Immunity. 2016 Feb 16; 2016 Feb 9. PMID: 26872695

Sempou E, Biasini E, Pinzón-Olejua A, Harris DA, Málaga-Trillo E: Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo. Mol Neurodegener. 2016 Feb 9; 2016 Feb 9. PMID: 26860872

Ellison D, Mugler A, Brennan MD, Lee SH, Huebner RJ, Shamir ER, Woo LA, Kim J, Amar P, Nemenman I, Ewald AJ, Levchenko A: Cell-cell communication enhances the capacity of cell ensembles to sense shallow gradients during morphogenesis. Proc Natl Acad Sci U S A. 2016 Feb 9; 2016 Jan 20. PMID: 26792522

Kim AK, DeRose R, Ueno T, Lin B, Komatsu T, Nakamura H, Inoue T: Toward total synthesis of cell function: Reconstituting cell dynamics with synthetic biology. Sci Signal. 2016 Feb 9; 2016 Feb 9. PMID: 26861045

Zhang Y, Liu C, Barbier O, Smalling R, Tsuchiya H, Lee S, Delker D, Zou A, Hagedorn CH, Wang L: Bcl2 is a critical regulator of bile acid homeostasis by dictating Shp and lncRNA H19 function. Sci Rep. 2016 Feb 3; 2016 Feb 3. PMID: 26838806

Erlenhardt N, Yu H, Abiraman K, Yamasaki T, Wadiche JI, Tomita S, Bredt DS: Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission. Cell Rep. 2016 Feb 2; 2016 Jan 14. PMID: 26776514

Dong J, Yu X, Porter DW, Battelli LA, Kashon ML, Ma Q: Common and distinct mechanisms of induced pulmonary fibrosis by particulate and soluble chemical fibrogenic agents. Arch Toxicol. 2016 Feb; 2015 Sep 7. PMID: 26345256

Marin EP, Jozsef L, Di Lorenzo A, Held KF, Luciano AK, Melendez J, Milstone LM, Velazquez H, Sessa WC: The Protein Acyl Transferase ZDHHC21 Modulates α1 Adrenergic Receptor Function and Regulates Hemodynamics. Arterioscler Thromb Vasc Biol. 2016 Feb; 2015 Dec 29. PMID: 26715683

Haas LT, Salazar SV, Kostylev MA, Um JW, Kaufman AC, Strittmatter SM: Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's disease. Brain. 2016 Feb; 2015 Dec 14. PMID: 26667279

Leung AW, Murdoch B, Salem AF, Prasad MS, Gomez GA, García-Castro MI: WNT/β-catenin signaling mediates human neural crest induction via a pre-neural border intermediate. Development. 2016 Feb 1. PMID: 26839343

Varadan V, Kamalakaran S, Gilmore H, Banerjee N, Janevski A, Miskimen KL, Williams N, Basavanhalli A, Madabhushi A, Lezon-Geyda K, Bossuyt V, Lannin DR, Abu-Khalaf M, Sikov W, Dimitrova N, Harris LN: Brief-exposure to preoperative bevacizumab reveals a TGF-β signature predictive of response in HER2-negative breast cancers. Int J Cancer. 2016 Feb 1; 2015 Aug 31. PMID: 26284485

Zaha VG, Qi D, Su KN, Palmeri M, Lee HY, Hu X, Wu X, Shulman GI, Rabinovitch PS, Russell RR 3rd, Young LH: AMPK is critical for mitochondrial function during reperfusion after myocardial ischemia. J Mol Cell Cardiol. 2016 Feb; 2015 Dec 30. PMID: 26746142

Azkona G, Saavedra A, Aira Z, Aluja D, Xifró X, Baguley T, Alberch J, Ellman JA, Lombroso PJ, Azkue JJ, Pérez-Navarro E: Striatal-enriched protein tyrosine phosphatase modulates nociception: evidence from genetic deletion and pharmacological inhibition. Pain. 2016 Feb. PMID: 26270590

Herbert KM, Sarkar SK, Mills M, Delgado De la Herran HC, Neuman KC, Steitz JA: A heterotrimer model of the complete Microprocessor complex revealed by single-molecule subunit counting. RNA. 2016 Feb; 2015 Dec 18. PMID: 26683315

Wree A, Mehal WZ, Feldstein AE: Targeting Cell Death and Sterile Inflammation Loop for the Treatment of Nonalcoholic Steatohepatitis. Semin Liver Dis. 2016 Feb; 2016 Feb 12. PMID: 26870930

Sestan-Pesa M, Horvath TL: Metabolism and Mental Illness. Trends Mol Med. 2016 Feb; 2016 Jan 14. PMID: 26776095

Block H, Stadtmann A, Riad D, Rossaint J, Sohlbach C, Germena G, Wu D, Simon SI, Ley K, Zarbock A: Gnb isoforms control a signaling pathway comprising Rac1, Plcβ2, and Plcβ3 leading to LFA-1 activation and neutrophil arrest in vivo. Blood. 2016 Jan 21; 2015 Oct 14. PMID: 26468229

Jeong J, VanHouten JN, Dann P, Kim W, Sullivan C, Yu H, Liotta L, Espina V, Stern DF, Friedman PA, Wysolmerski JJ: PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer. Proc Natl Acad Sci U S A. 2016 Jan 19; 2016 Jan 4. PMID: 26729871

Kraehling JR, Hao Z, Lee MY, Vinyard DJ, Velazquez H, Liu X, Stan RV, Brudvig GW, Sessa WC: Uncoupling Caveolae From Intracellular Signaling In Vivo. Circ Res. 2016 Jan 8; 2015 Nov 24. PMID: 26602865

Chamorro-Jorganes A, Lee MY, Araldi E, Landskroner-Eiger S, Fernández-Fuertes M, Sahraei M, Quiles Del Rey M, van Solingen C, Yu J, Fernández-Hernando C, Sessa WC, Suárez Y: VEGF-Induced Expression of miR-17-92 Cluster in Endothelial Cells Is Mediated by ERK/ELK1 Activation and Regulates Angiogenesis. Circ Res. 2016 Jan 8; 2015 Oct 15. PMID: 26472816

Gou X, Tang X, Kong DK, He X, Gao X, Guo N, Hu Z, Zhao Z, Chen Y: CD147 is increased in HCC cells under starvation and reduces cell death through upregulating p-mTOR in vitro. Apoptosis. 2016 Jan. PMID: 26496775

Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, Agnello M, Agostinis P, Aguilar PV, Aguirre-Ghiso J, Airoldi EM, Ait-Si-Ali S, Akematsu T, Akporiaye ET, Al-Rubeai M, Albaiceta GM, Albanese C, Albani D, Albert ML, Aldudo J, Algül H, Alirezaei M, Alloza I, Almasan A, Almonte-Beceril M, Alnemri ES, Alonso C, Altan-Bonnet N, Altieri DC, Alvarez S, Alvarez-Erviti L, Alves S, Amadoro G, Amano A, Amantini C, Ambrosio S, Amelio I, Amer AO, Amessou M, Amon A, An Z, Anania FA, Andersen SU, Andley UP, Andreadi CK, Andrieu-Abadie N, Anel A, Ann DK, Anoopkumar-Dukie S, Antonioli M, Aoki H, Apostolova N, Aquila S, Aquilano K, Araki K, Arama E, Aranda A, Araya J, Arcaro A, Arias E, Arimoto H, Ariosa AR, Armstrong JL, Arnould T, Arsov I, Asanuma K, Askanas V, Asselin E, Atarashi R, Atherton SS, Atkin JD, Attardi LD, Auberger P, Auburger G, Aurelian L, Autelli R, Avagliano L, Avantaggiati ML, Avrahami L, Awale S, Azad N, Bachetti T, Backer JM, Bae DH, Bae JS, Bae ON, Bae SH, Baehrecke EH, Baek SH, Baghdiguian S, Bagniewska-Zadworna A, Bai H, Bai J, Bai XY, Bailly Y, Balaji KN, Balduini W, Ballabio A, Balzan R, Banerjee R, Bánhegyi G, Bao H, Barbeau B, Barrachina MD, Barreiro E, Bartel B, Bartolomé A, Bassham DC, Bassi MT, Bast RC Jr, Basu A, Batista MT, Batoko H, Battino M, Bauckman K, Baumgarner BL, Bayer KU, Beale R, Beaulieu JF, Beck GR Jr, Becker C, Beckham JD, Bédard PA, Bednarski PJ, Begley TJ, Behl C, Behrends C, Behrens GM, Behrns KE, Bejarano E, Belaid A, Belleudi F, Bénard G, Berchem G, Bergamaschi D, Bergami M, Berkhout B, Berliocchi L, Bernard A, Bernard M, Bernassola F, Bertolotti A, Bess AS, Besteiro S, Bettuzzi S, Bhalla S, Bhattacharyya S, Bhutia SK, Biagosch C, Bianchi MW, Biard-Piechaczyk M, Billes V, Bincoletto C, Bingol B, Bird SW, Bitoun M, Bjedov I, Blackstone C, Blanc L, Blanco GA, Blomhoff HK, Boada-Romero E, Böckler S, Boes M, Boesze-Battaglia K, Boise LH, Bolino A, Boman A, Bonaldo P, Bordi M, Bosch J, Botana LM, Botti J, Bou G, Bouché M, Bouchecareilh M, Boucher MJ, Boulton ME, Bouret SG, Boya P, Boyer-Guittaut M, Bozhkov PV, Brady N, Braga VM, Brancolini C, Braus GH, Bravo-San Pedro JM, Brennan LA, Bresnick EH, Brest P, Bridges D, Bringer MA, Brini M, Brito GC, Brodin B, Brookes PS, Brown EJ, Brown K, Broxmeyer HE, Bruhat A, Brum PC, Brumell JH, Brunetti-Pierri N, Bryson-Richardson RJ, Buch S, Buchan AM, Budak H, Bulavin DV, Bultman SJ, Bultynck G, Bumbasirevic V, Burelle Y, Burke RE, Burmeister M, Bütikofer P, Caberlotto L, Cadwell K, Cahova M, Cai D, Cai J, Cai Q, Calatayud S, Camougrand N, Campanella M, Campbell GR, Campbell M, Campello S, Candau R, Caniggia I, Cantoni L, Cao L, Caplan AB, Caraglia M, Cardinali C, Cardoso SM, Carew JS, Carleton LA, Carlin CR, Carloni S, Carlsson SR, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carra S, Carrier A, Carroll B, Casas C, Casas J, Cassinelli G, Castets P, Castro-Obregon S, Cavallini G, Ceccherini I, Cecconi F, Cederbaum AI, Ceña V, Cenci S, Cerella C, Cervia D, Cetrullo S, Chaachouay H, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chamilos G, Chan EY, Chan MT, Chandra D, Chandra P, Chang CP, Chang RC, Chang TY, Chatham JC, Chatterjee S, Chauhan S, Che Y, Cheetham ME, Cheluvappa R, Chen CJ, Chen G, Chen GC, Chen G, Chen H, Chen JW, Chen JK, Chen M, Chen M, Chen P, Chen Q, Chen Q, Chen SD, Chen S, Chen SS, Chen W, Chen WJ, Chen WQ, Chen W, Chen X, Chen YH, Chen YG, Chen Y, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen Y, Chen Z, Chen Z, Cheng A, Cheng CH, Cheng H, Cheong H, Cherry S, Chesney J, Cheung CH, Chevet E, Chi HC, Chi SG, Chiacchiera F, Chiang HL, Chiarelli R, Chiariello M, Chieppa M, Chin LS, Chiong M, Chiu GN, Cho DH, Cho SG, Cho WC, Cho YY, Cho YS, Choi AM, Choi EJ, Choi EK, Choi J, Choi ME, Choi SI, Chou TF, Chouaib S, Choubey D, Choubey V, Chow KC, Chowdhury K, Chu CT, Chuang TH, Chun T, Chung H, Chung T, Chung YL, Chwae YJ, Cianfanelli V, Ciarcia R, Ciechomska IA, Ciriolo MR, Cirone M, Claerhout S, Clague MJ, Clària J, Clarke PG, Clarke R, Clementi E, Cleyrat C, Cnop M, Coccia EM, Cocco T, Codogno P, Coers J, Cohen EE, Colecchia D, Coletto L, Coll NS, Colucci-Guyon E, Comincini S, Condello M, Cook KL, Coombs GH, Cooper CD, Cooper JM, Coppens I, Corasaniti MT, Corazzari M, Corbalan R, Corcelle-Termeau E, Cordero MD, Corral-Ramos C, Corti O, Cossarizza A, Costelli P, Costes S, Cotman SL, Coto-Montes A, Cottet S, Couve E, Covey LR, Cowart LA, Cox JS, Coxon FP, Coyne CB, Cragg MS, Craven RJ, Crepaldi T, Crespo JL, Criollo A, Crippa V, Cruz MT, Cuervo AM, Cuezva JM, Cui T, Cutillas PR, Czaja MJ, Czyzyk-Krzeska MF, Dagda RK, Dahmen U, Dai C, Dai W, Dai Y, Dalby KN, Dalla Valle L, Dalmasso G, D'Amelio M, Damme M, Darfeuille-Michaud A, Dargemont C, Darley-Usmar VM, Dasarathy S, Dasgupta B, Dash S, Dass CR, Davey HM, Davids LM, Dávila D, Davis RJ, Dawson TM, Dawson VL, Daza P, de Belleroche J, de Figueiredo P, de Figueiredo RC, de la Fuente J, De Martino L, De Matteis A, De Meyer GR, De Milito A, De Santi M, de Souza W, De Tata V, De Zio D, Debnath J, Dechant R, Decuypere JP, Deegan S, Dehay B, Del Bello B, Del Re DP, Delage-Mourroux R, Delbridge LM, Deldicque L, Delorme-Axford E, Deng Y, Dengjel J, Denizot M, Dent P, Der CJ, Deretic V, Derrien B, Deutsch E, Devarenne TP, Devenish RJ, Di Bartolomeo S, Di Daniele N, Di Domenico F, Di Nardo A, Di Paola S, Di Pietro A, Di Renzo L, DiAntonio A, Díaz-Araya G, Díaz-Laviada I, Diaz-Meco MT, Diaz-Nido J, Dickey CA, Dickson RC, Diederich M, Digard P, Dikic I, Dinesh-Kumar SP, Ding C, Ding WX, Ding Z, Dini L, Distler JH, Diwan A, Djavaheri-Mergny M, Dmytruk K, Dobson RC, Doetsch V, Dokladny K, Dokudovskaya S, Donadelli M, Dong XC, Dong X, Dong Z, Donohue TM Jr, Doran KS, D'Orazi G, Dorn GW 2nd, Dosenko V, Dridi S, Drucker L, Du J, Du LL, Du L, du Toit A, Dua P, Duan L, Duann P, Dubey VK, Duchen MR, Duchosal MA, Duez H, Dugail I, Dumit VI, Duncan MC, Dunlop EA, Dunn WA Jr, Dupont N, Dupuis L, Durán RV, Durcan TM, Duvezin-Caubet S, Duvvuri U, Eapen V, Ebrahimi-Fakhari D, Echard A, Eckhart L, Edelstein CL, Edinger AL, Eichinger L, Eisenberg T, Eisenberg-Lerner A, Eissa NT, El-Deiry WS, El-Khoury V, Elazar Z, Eldar-Finkelman H, Elliott CJ, Emanuele E, Emmenegger U, Engedal N, Engelbrecht AM, Engelender S, Enserink JM, Erdmann R, Erenpreisa J, Eri R, Eriksen JL, Erman A, Escalante R, Eskelinen EL, Espert L, Esteban-Martínez L, Evans TJ, Fabri M, Fabrias G, Fabrizi C, Facchiano A, Færgeman NJ, Faggioni A, Fairlie WD, Fan C, Fan D, Fan J, Fang S, Fanto M, Fanzani A, Farkas T, Faure M, Favier FB, Fearnhead H, Federici M, Fei E, Felizardo TC, Feng H, Feng Y, Feng Y, Ferguson TA, Fernández ÁF, Fernandez-Barrena MG, Fernandez-Checa JC, Fernández-López A, Fernandez-Zapico ME, Feron O, Ferraro E, Ferreira-Halder CV, Fesus L, Feuer R, Fiesel FC, Filippi-Chiela EC, Filomeni G, Fimia GM, Fingert JH, Finkbeiner S, Finkel T, Fiorito F, Fisher PB, Flajolet M, Flamigni F, Florey O, Florio S, Floto RA, Folini M, Follo C, Fon EA, Fornai F, Fortunato F, Fraldi A, Franco R, Francois A, François A, Frankel LB, Fraser ID, Frey N, Freyssenet DG, Frezza C, Friedman SL, Frigo DE, Fu D, Fuentes JM, Fueyo J, Fujitani Y, Fujiwara Y, Fujiya M, Fukuda M, Fulda S, Fusco C, Gabryel B, Gaestel M, Gailly P, Gajewska M, Galadari S, Galili G, Galindo I, Galindo MF, Galliciotti G, Galluzzi L, Galluzzi L, Galy V, Gammoh N, Gandy S, Ganesan AK, Ganesan S, Ganley IG, Gannagé M, Gao FB, Gao F, Gao JX, García Nannig L, García Véscovi E, Garcia-Macía M, Garcia-Ruiz C, Garg AD, Garg PK, Gargini R, Gassen NC, Gatica D, Gatti E, Gavard J, Gavathiotis E, Ge L, Ge P, Ge S, Gean PW, Gelmetti V, Genazzani AA, Geng J, Genschik P, Gerner L, Gestwicki JE, Gewirtz DA, Ghavami S, Ghigo E, Ghosh D, Giammarioli AM, Giampieri F, Giampietri C, Giatromanolaki A, Gibbings DJ, Gibellini L, Gibson SB, Ginet V, Giordano A, Giorgini F, Giovannetti E, Girardin SE, Gispert S, Giuliano S, Gladson CL, Glavic A, Gleave M, Godefroy N, Gogal RM Jr, Gokulan K, Goldman GH, Goletti D, Goligorsky MS, Gomes AV, Gomes LC, Gomez H, Gomez-Manzano C, Gómez-Sánchez R, Gonçalves DA, Goncu E, Gong Q, Gongora C, Gonzalez CB, Gonzalez-Alegre P, Gonzalez-Cabo P, González-Polo RA, Goping IS, Gorbea C, Gorbunov NV, Goring DR, Gorman AM, Gorski SM, Goruppi S, Goto-Yamada S, Gotor C, Gottlieb RA, Gozes I, Gozuacik D, Graba Y, Graef M, Granato GE, Grant GD, Grant S, Gravina GL, Green DR, Greenhough A, Greenwood MT, Grimaldi B, Gros F, Grose C, Groulx JF, Gruber F, Grumati P, Grune T, Guan JL, Guan KL, Guerra B, Guillen C, Gulshan K, Gunst J, Guo C, Guo L, Guo M, Guo W, Guo XG, Gust AA, Gustafsson ÅB, Gutierrez E, Gutierrez MG, Gwak HS, Haas A, Haber JE, Hadano S, Hagedorn M, Hahn DR, Halayko AJ, Hamacher-Brady A, Hamada K, Hamai A, Hamann A, Hamasaki M, Hamer I, Hamid Q, Hammond EM, Han F, Han W, Handa JT, Hanover JA, Hansen M, Harada M, Harhaji-Trajkovic L, Harper JW, Harrath AH, Harris AL, Harris J, Hasler U, Hasselblatt P, Hasui K, Hawley RG, Hawley TS, He C, He CY, He F, He G, He RR, He XH, He YW, He YY, Heath JK, Hébert MJ, Heinzen RA, Helgason GV, Hensel M, Henske EP, Her C, Herman PK, Hernández A, Hernandez C, Hernández-Tiedra S, Hetz C, Hiesinger PR, Higaki K, Hilfiker S, Hill BG, Hill JA, Hill WD, Hino K, Hofius D, Hofman P, Höglinger GU, Höhfeld J, Holz MK, Hong Y, Hood DA, Hoozemans JJ, Hoppe T, Hsu C, Hsu CY, Hsu LC, Hu D, Hu G, Hu HM, Hu H, Hu MC, Hu YC, Hu ZW, Hua F, Hua Y, Huang C, Huang HL, Huang KH, Huang KY, Huang S, Huang S, Huang WP, Huang YR, Huang Y, Huang Y, Huber TB, Huebbe P, Huh WK, Hulmi JJ, Hur GM, Hurley JH, Husak Z, Hussain SN, Hussain S, Hwang JJ, Hwang S, Hwang TI, Ichihara A, Imai Y, Imbriano C, Inomata M, Into T, Iovane V, Iovanna JL, Iozzo RV, Ip NY, Irazoqui JE, Iribarren P, Isaka Y, Isakovic AJ, Ischiropoulos H, Isenberg JS, Ishaq M, Ishida H, Ishii I, Ishmael JE, Isidoro C, Isobe K, Isono E, Issazadeh-Navikas S, Itahana K, Itakura E, Ivanov AI, Iyer AK, Izquierdo JM, Izumi Y, Izzo V, Jäättelä M, Jaber N, Jackson DJ, Jackson WT, Jacob TG, Jacques TS, Jagannath C, Jain A, Jana NR, Jang BK, Jani A, Janji B, Jannig PR, Jansson PJ, Jean S, Jendrach M, Jeon JH, Jessen N, Jeung EB, Jia K, Jia L, Jiang H, Jiang H, Jiang L, Jiang T, Jiang X, Jiang X, Jiang X, Jiang Y, Jiang Y, Jiménez A, Jin C, Jin H, Jin L, Jin M, Jin S, Jinwal UK, Jo EK, Johansen T, Johnson DE, Johnson GV, Johnson JD, Jonasch E, Jones C, Joosten LA, Jordan J, Joseph AM, Joseph B, Joubert AM, Ju D, Ju J, Juan HF, Juenemann K, Juhász G, Jung HS, Jung JU, Jung YK, Jungbluth H, Justice MJ, Jutten B, Kaakoush NO, Kaarniranta K, Kaasik A, Kabuta T, Kaeffer B, Kågedal K, Kahana A, Kajimura S, Kakhlon O, Kalia M, Kalvakolanu DV, Kamada Y, Kambas K, Kaminskyy VO, Kampinga HH, Kandouz M, Kang C, Kang R, Kang TC, Kanki T, Kanneganti TD, Kanno H, Kanthasamy AG, Kantorow M, Kaparakis-Liaskos M, Kapuy O, Karantza V, Karim MR, Karmakar P, Kaser A, Kaushik S, Kawula T, Kaynar AM, Ke PY, Ke ZJ, Kehrl JH, Keller KE, Kemper JK, Kenworthy AK, Kepp O, Kern A, Kesari S, Kessel D, Ketteler R, Kettelhut Ido C, Khambu B, Khan MM, Khandelwal VK, Khare S, Kiang JG, Kiger AA, Kihara A, Kim AL, Kim CH, Kim DR, Kim DH, Kim EK, Kim HY, Kim HR, Kim JS, Kim JH, Kim JC, Kim JH, Kim KW, Kim MD, Kim MM, Kim PK, Kim SW, Kim SY, Kim YS, Kim Y, Kimchi A, Kimmelman AC, Kimura T, King JS, Kirkegaard K, Kirkin V, Kirshenbaum LA, Kishi S, Kitajima Y, Kitamoto K, Kitaoka Y, Kitazato K, Kley RA, Klimecki WT, Klinkenberg M, Klucken J, Knævelsrud H, Knecht E, Knuppertz L, Ko JL, Kobayashi S, Koch JC, Koechlin-Ramonatxo C, Koenig U, Koh YH, Köhler K, Kohlwein SD, Koike M, Komatsu M, Kominami E, Kong D, Kong HJ, Konstantakou EG, Kopp BT, Korcsmaros T, Korhonen L, Korolchuk VI, Koshkina NV, Kou Y, Koukourakis MI, Koumenis C, Kovács AL, Kovács T, Kovacs WJ, Koya D, Kraft C, Krainc D, Kramer H, Kravic-Stevovic T, Krek W, Kretz-Remy C, Krick R, Krishnamurthy M, Kriston-Vizi J, Kroemer G, Kruer MC, Kruger R, Ktistakis NT, Kuchitsu K, Kuhn C, Kumar AP, Kumar A, Kumar A, Kumar D, Kumar D, Kumar R, Kumar S, Kundu M, Kung HJ, Kuno A, Kuo SH, Kuret J, Kurz T, Kwok T, Kwon TK, Kwon YT, Kyrmizi I, La Spada AR, Lafont F, Lahm T, Lakkaraju A, Lam T, Lamark T, Lancel S, Landowski TH, Lane DJ, Lane JD, Lanzi C, Lapaquette P, Lapierre LR, Laporte J, Laukkarinen J, Laurie GW, Lavandero S, Lavie L, LaVoie MJ, Law BY, Law HK, Law KB, Layfield R, Lazo PA, Le Cam L, Le Roch KG, Le Stunff H, Leardkamolkarn V, Lecuit M, Lee BH, Lee CH, Lee EF, Lee GM, Lee HJ, Lee H, Lee JK, Lee J, Lee JH, Lee JH, Lee M, Lee MS, Lee PJ, Lee SW, Lee SJ, Lee SJ, Lee SY, Lee SH, Lee SS, Lee SJ, Lee S, Lee YR, Lee YJ, Lee YH, Leeuwenburgh C, Lefort S, Legouis R, Lei J, Lei QY, Leib DA, Leibowitz G, Lekli I, Lemaire SD, Lemasters JJ, Lemberg MK, Lemoine A, Leng S, Lenz G, Lenzi P, Lerman LO, Lettieri Barbato D, Leu JI, Leung HY, Levine B, Lewis PA, Lezoualc'h F, Li C, Li F, Li FJ, Li J, Li K, Li L, Li M, Li M, Li Q, Li R, Li S, Li W, Li W, Li X, Li Y, Lian J, Liang C, Liang Q, Liao Y, Liberal J, Liberski PP, Lie P, Lieberman AP, Lim HJ, Lim KL, Lim K, Lima RT, Lin CS, Lin CF, Lin F, Lin F, Lin FC, Lin K, Lin KH, Lin PH, Lin T, Lin WW, Lin YS, Lin Y, Linden R, Lindholm D, Lindqvist LM, Lingor P, Linkermann A, Liotta LA, Lipinski MM, Lira VA, Lisanti MP, Liton PB, Liu B, Liu C, Liu CF, Liu F, Liu HJ, Liu J, Liu JJ, Liu JL, Liu K, Liu L, Liu L, Liu Q, Liu RY, Liu S, Liu S, Liu W, Liu XD, Liu X, Liu XH, Liu X, Liu X, Liu X, Liu Y, Liu Y, Liu Z, Liu Z, Liuzzi JP, Lizard G, Ljujic M, Lodhi IJ, Logue SE, Lokeshwar BL, Long YC, Lonial S, Loos B, López-Otín C, López-Vicario C, Lorente M, Lorenzi PL, Lõrincz P, Los M, Lotze MT, Lovat PE, Lu B, Lu B, Lu J, Lu Q, Lu SM, Lu S, Lu Y, Luciano F, Luckhart S, Lucocq JM, Ludovico P, Lugea A, Lukacs NW, Lum JJ, Lund AH, Luo H, Luo J, Luo S, Luparello C, Lyons T, Ma J, Ma Y, Ma Y, Ma Z, Machado J, Machado-Santelli GM, Macian F, MacIntosh GC, MacKeigan JP, Macleod KF, MacMicking JD, MacMillan-Crow LA, Madeo F, Madesh M, Madrigal-Matute J, Maeda A, Maeda T, Maegawa G, Maellaro E, Maes H, Magariños M, Maiese K, Maiti TK, Maiuri L, Maiuri MC, Maki CG, Malli R, Malorni W, Maloyan A, Mami-Chouaib F, Man N, Mancias JD, Mandelkow EM, Mandell MA, Manfredi AA, Manié SN, Manzoni C, Mao K, Mao Z, Mao ZW, Marambaud P, Marconi AM, Marelja Z, Marfe G, Margeta M, Margittai E, Mari M, Mariani FV, Marin C, Marinelli S, Mariño G, Markovic I, Marquez R, Martelli AM, Martens S, Martin KR, Martin SJ, Martin S, Martin-Acebes MA, Martín-Sanz P, Martinand-Mari C, Martinet W, Martinez J, Martinez-Lopez N, Martinez-Outschoorn U, Martínez-Velázquez M, Martinez-Vicente M, Martins WK, Mashima H, Mastrianni JA, Matarese G, Matarrese P, Mateo R, Matoba S, Matsumoto N, Matsushita T, Matsuura A, Matsuzawa T, Mattson MP, Matus S, Maugeri N, Mauvezin C, Mayer A, Maysinger D, Mazzolini GD, McBrayer MK, McCall K, McCormick C, McInerney GM, McIver SC, McKenna S, McMahon JJ, McNeish IA, Mechta-Grigoriou F, Medema JP, Medina DL, Megyeri K, Mehrpour M, Mehta JL, Mei Y, Meier UC, Meijer AJ, Meléndez A, Melino G, Melino S, de Melo EJ, Mena MA, Meneghini MD, Menendez JA, Menezes R, Meng L, Meng LH, Meng S, Menghini R, Menko AS, Menna-Barreto RF, Menon MB, Meraz-Ríos MA, Merla G, Merlini L, Merlot AM, Meryk A, Meschini S, Meyer JN, Mi MT, Miao CY, Micale L, Michaeli S, Michiels C, Migliaccio AR, Mihailidou AS, Mijaljica D, Mikoshiba K, Milan E, Miller-Fleming L, Mills GB, Mills IG, Minakaki G, Minassian BA, Ming XF, Minibayeva F, Minina EA, Mintern JD, Minucci S, Miranda-Vizuete A, Mitchell CH, Miyamoto S, Miyazawa K, Mizushima N, Mnich K, Mograbi B, Mohseni S, Moita LF, Molinari M, Molinari M, Møller AB, Mollereau B, Mollinedo F, Mongillo M, Monick MM, Montagnaro S, Montell C, Moore DJ, Moore MN, Mora-Rodriguez R, Moreira PI, Morel E, Morelli MB, Moreno S, Morgan MJ, Moris A, Moriyasu Y, Morrison JL, Morrison LA, Morselli E, Moscat J, Moseley PL, Mostowy S, Motori E, Mottet D, Mottram JC, Moussa CE, Mpakou VE, Mukhtar H, Mulcahy Levy JM, Muller S, Muñoz-Moreno R, Muñoz-Pinedo C, Münz C, Murphy ME, Murray JT, Murthy A, Mysorekar IU, Nabi IR, Nabissi M, Nader GA, Nagahara Y, Nagai Y, Nagata K, Nagelkerke A, Nagy P, Naidu SR, Nair S, Nakano H, Nakatogawa H, Nanjundan M, Napolitano G, Naqvi NI, Nardacci R, Narendra DP, Narita M, Nascimbeni AC, Natarajan R, Navegantes LC, Nawrocki ST, Nazarko TY, Nazarko VY, Neill T, Neri LM, Netea MG, Netea-Maier RT, Neves BM, Ney PA, Nezis IP, Nguyen HT, Nguyen HP, Nicot AS, Nilsen H, Nilsson P, Nishimura M, Nishino I, Niso-Santano M, Niu H, Nixon RA, Njar VC, Noda T, Noegel AA, Nolte EM, Norberg E, Norga KK, Noureini SK, Notomi S, Notterpek L, Nowikovsky K, Nukina N, Nürnberger T, O'Donnell VB, O'Donovan T, O'Dwyer PJ, Oehme I, Oeste CL, Ogawa M, Ogretmen B, Ogura Y, Oh YJ, Ohmuraya M, Ohshima T, Ojha R, Okamoto K, Okazaki T, Oliver FJ, Ollinger K, Olsson S, Orban DP, Ordonez P, Orhon I, Orosz L, O'Rourke EJ, Orozco H, Ortega AL, Ortona E, Osellame LD, Oshima J, Oshima S, Osiewacz HD, Otomo T, Otsu K, Ou JH, Outeiro TF, Ouyang DY, Ouyang H, Overholtzer M, Ozbun MA, Ozdinler PH, Ozpolat B, Pacelli C, Paganetti P, Page G, Pages G, Pagnini U, Pajak B, Pak SC, Pakos-Zebrucka K, Pakpour N, Palková Z, Palladino F, Pallauf K, Pallet N, Palmieri M, Paludan SR, Palumbo C, Palumbo S, Pampliega O, Pan H, Pan W, Panaretakis T, Pandey A, Pantazopoulou A, Papackova Z, Papademetrio DL, Papassideri I, Papini A, Parajuli N, Pardo J, Parekh VV, Parenti G, Park JI, Park J, Park OK, Parker R, Parlato R, Parys JB, Parzych KR, Pasquet JM, Pasquier B, Pasumarthi KB, Patschan D, Patterson C, Pattingre S, Pattison S, Pause A, Pavenstädt H, Pavone F, Pedrozo Z, Peña FJ, Peñalva MA, Pende M, Peng J, Penna F, Penninger JM, Pensalfini A, Pepe S, Pereira GJ, Pereira PC, Pérez-de la Cruz V, Pérez-Pérez ME, Pérez-Rodríguez D, Pérez-Sala D, Perier C, Perl A, Perlmutter DH, Perrotta I, Pervaiz S, Pesonen M, Pessin JE, Peters GJ, Petersen M, Petrache I, Petrof BJ, Petrovski G, Phang JM, Piacentini M, Pierdominici M, Pierre P, Pierrefite-Carle V, Pietrocola F, Pimentel-Muiños FX, Pinar M, Pineda B, Pinkas-Kramarski R, Pinti M, Pinton P, Piperdi B, Piret JM, Platanias LC, Platta HW, Plowey ED, Pöggeler S, Poirot M, Polčic P, Poletti A, Poon AH, Popelka H, Popova B, Poprawa I, Poulose SM, Poulton J, Powers SK, Powers T, Pozuelo-Rubio M, Prak K, Prange R, Prescott M, Priault M, Prince S, Proia RL, Proikas-Cezanne T, Prokisch H, Promponas VJ, Przyklenk K, Puertollano R, Pugazhenthi S, Puglielli L, Pujol A, Puyal J, Pyeon D, Qi X, Qian WB, Qin ZH, Qiu Y, Qu Z, Quadrilatero J, Quinn F, Raben N, Rabinowich H, Radogna F, Ragusa MJ, Rahmani M, Raina K, Ramanadham S, Ramesh R, Rami A, Randall-Demllo S, Randow F, Rao H, Rao VA, Rasmussen BB, Rasse TM, Ratovitski EA, Rautou PE, Ray SK, Razani B, Reed BH, Reggiori F, Rehm M, Reichert AS, Rein T, Reiner DJ, Reits E, Ren J, Ren X, Renna M, Reusch JE, Revuelta JL, Reyes L, Rezaie AR, Richards RI, Richardson DR, Richetta C, Riehle MA, Rihn BH, Rikihisa Y, Riley BE, Rimbach G, Rippo MR, Ritis K, Rizzi F, Rizzo E, Roach PJ, Robbins J, Roberge M, Roca G, Roccheri MC, Rocha S, Rodrigues CM, Rodríguez CI, de Cordoba SR, Rodriguez-Muela N, Roelofs J, Rogov VV, Rohn TT, Rohrer B, Romanelli D, Romani L, Romano PS, Roncero MI, Rosa JL, Rosello A, Rosen KV, Rosenstiel P, Rost-Roszkowska M, Roth KA, Roué G, Rouis M, Rouschop KM, Ruan DT, Ruano D, Rubinsztein DC, Rucker EB 3rd, Rudich A, Rudolf E, Rudolf R, Ruegg MA, Ruiz-Roldan C, Ruparelia AA, Rusmini P, Russ DW, Russo GL, Russo G, Russo R, Rusten TE, Ryabovol V, Ryan KM, Ryter SW, Sabatini DM, Sacher M, Sachse C, Sack MN, Sadoshima J, Saftig P, Sagi-Eisenberg R, Sahni S, Saikumar P, Saito T, Saitoh T, Sakakura K, Sakoh-Nakatogawa M, Sakuraba Y, Salazar-Roa M, Salomoni P, Saluja AK, Salvaterra PM, Salvioli R, Samali A, Sanchez AM, Sánchez-Alcázar JA, Sanchez-Prieto R, Sandri M, Sanjuan MA, Santaguida S, Santambrogio L, Santoni G, Dos Santos CN, Saran S, Sardiello M, Sargent G, Sarkar P, Sarkar S, Sarrias MR, Sarwal MM, Sasakawa C, Sasaki M, Sass M, Sato K, Sato M, Satriano J, Savaraj N, Saveljeva S, Schaefer L, Schaible UE, Scharl M, Schatzl HM, Schekman R, Scheper W, Schiavi A, Schipper HM, Schmeisser H, Schmidt J, Schmitz I, Schneider BE, Schneider EM, Schneider JL, Schon EA, Schönenberger MJ, Schönthal AH, Schorderet DF, Schröder B, Schuck S, Schulze RJ, Schwarten M, Schwarz TL, Sciarretta S, Scotto K, Scovassi AI, Screaton RA, Screen M, Seca H, Sedej S, Segatori L, Segev N, Seglen PO, Seguí-Simarro JM, Segura-Aguilar J, Seki E, Sell C, Seiliez I, Semenkovich CF, Semenza GL, Sen U, Serra AL, Serrano-Puebla A, Sesaki H, Setoguchi T, Settembre C, Shacka JJ, Shajahan-Haq AN, Shapiro IM, Sharma S, She H, Shen CK, Shen CC, Shen HM, Shen S, Shen W, Sheng R, Sheng X, Sheng ZH, Shepherd TG, Shi J, Shi Q, Shi Q, Shi Y, Shibutani S, Shibuya K, Shidoji Y, Shieh JJ, Shih CM, Shimada Y, Shimizu S, Shin DW, Shinohara ML, Shintani M, Shintani T, Shioi T, Shirabe K, Shiri-Sverdlov R, Shirihai O, Shore GC, Shu CW, Shukla D, Sibirny AA, Sica V, Sigurdson CJ, Sigurdsson EM, Sijwali PS, Sikorska B, Silveira WA, Silvente-Poirot S, Silverman GA, Simak J, Simmet T, Simon AK, Simon HU, Simone C, Simons M, Simonsen A, Singh R, Singh SV, Singh SK, Sinha D, Sinha S, Sinicrope FA, Sirko A, Sirohi K, Sishi BJ, Sittler A, Siu PM, Sivridis E, Skwarska A, Slack R, Slaninová I, Slavov N, Smaili SS, Smalley KS, Smith DR, Soenen SJ, Soleimanpour SA, Solhaug A, Somasundaram K, Son JH, Sonawane A, Song C, Song F, Song HK, Song JX, Song W, Soo KY, Sood AK, Soong TW, Soontornniyomkij V, Sorice M, Sotgia F, Soto-Pantoja DR, Sotthibundhu A, Sousa MJ, Spaink HP, Span PN, Spang A, Sparks JD, Speck PG, Spector SA, Spies CD, Springer W, Clair DS, Stacchiotti A, Staels B, Stang MT, Starczynowski DT, Starokadomskyy P, Steegborn C, Steele JW, Stefanis L, Steffan J, Stellrecht CM, Stenmark H, Stepkowski TM, Stern ST, Stevens C, Stockwell BR, Stoka V, Storchova Z, Stork B, Stratoulias V, Stravopodis DJ, Strnad P, Strohecker AM, Ström AL, Stromhaug P, Stulik J, Su YX, Su Z, Subauste CS, Subramaniam S, Sue CM, Suh SW, Sui X, Sukseree S, Sulzer D, Sun FL, Sun J, Sun J, Sun SY, Sun Y, Sun Y, Sun Y, Sundaramoorthy V, Sung J, Suzuki H, Suzuki K, Suzuki N, Suzuki T, Suzuki YJ, Swanson MS, Swanton C, Swärd K, Swarup G, Sweeney ST, Sylvester PW, Szatmari Z, Szegezdi E, Szlosarek PW, Taegtmeyer H, Tafani M, Taillebourg E, Tait SW, Takacs-Vellai K, Takahashi Y, Takáts S, Takemura G, Takigawa N, Talbot NJ, Tamagno E, Tamburini J, Tan CP, Tan L, Tan ML, Tan M, Tan YJ, Tanaka K, Tanaka M, Tang D, Tang D, Tang G, Tanida I, Tanji K, Tannous BA, Tapia JA, Tasset-Cuevas I, Tatar M, Tavassoly I, Tavernarakis N, Taylor A, Taylor GS, Taylor GA, Taylor JP, Taylor MJ, Tchetina EV, Tee AR, Teixeira-Clerc F, Telang S, Tencomnao T, Teng BB, Teng RJ, Terro F, Tettamanti G, Theiss AL, Theron AE, Thomas KJ, Thomé MP, Thomes PG, Thorburn A, Thorner J, Thum T, Thumm M, Thurston TL, Tian L, Till A, Ting JP, Titorenko VI, Toker L, Toldo S, Tooze SA, Topisirovic I, Torgersen ML, Torosantucci L, Torriglia A, Torrisi MR, Tournier C, Towns R, Trajkovic V, Travassos LH, Triola G, Tripathi DN, Trisciuoglio D, Troncoso R, Trougakos IP, Truttmann AC, Tsai KJ, Tschan MP, Tseng YH, Tsukuba T, Tsung A, Tsvetkov AS, Tu S, Tuan HY, Tucci M, Tumbarello DA, Turk B, Turk V, Turner RF, Tveita AA, Tyagi SC, Ubukata M, Uchiyama Y, Udelnow A, Ueno T, Umekawa M, Umemiya-Shirafuji R, Underwood BR, Ungermann C, Ureshino RP, Ushioda R, Uversky VN, Uzcátegui NL, Vaccari T, Vaccaro MI, Váchová L, Vakifahmetoglu-Norberg H, Valdor R, Valente EM, Vallette F, Valverde AM, Van den Berghe G, Van Den Bosch L, van den Brink GR, van der Goot FG, van der Klei IJ, van der Laan LJ, van Doorn WG, van Egmond M, van Golen KL, Van Kaer L, van Lookeren Campagne M, Vandenabeele P, Vandenberghe W, Vanhorebeek I, Varela-Nieto I, Vasconcelos MH, Vasko R, Vavvas DG, Vega-Naredo I, Velasco G, Velentzas AD, Velentzas PD, Vellai T, Vellenga E, Vendelbo MH, Venkatachalam K, Ventura N, Ventura S, Veras PS, Verdier M, Vertessy BG, Viale A, Vidal M, Vieira HL, Vierstra RD, Vigneswaran N, Vij N, Vila M, Villar M, Villar VH, Villarroya J, Vindis C, Viola G, Viscomi MT, Vitale G, Vogl DT, Voitsekhovskaja OV, von Haefen C, von Schwarzenberg K, Voth DE, Vouret-Craviari V, Vuori K, Vyas JM, Waeber C, Walker CL, Walker MJ, Walter J, Wan L, Wan X, Wang B, Wang C, Wang CY, Wang C, Wang C, Wang C, Wang D, Wang F, Wang F, Wang G, Wang HJ, Wang H, Wang HG, Wang H, Wang HD, Wang J, Wang J, Wang M, Wang MQ, Wang PY, Wang P, Wang RC, Wang S, Wang TF, Wang X, Wang XJ, Wang XW, Wang X, Wang X, Wang Y, Wang Y, Wang Y, Wang YJ, Wang Y, Wang Y, Wang YT, Wang Y, Wang ZN, Wappner P, Ward C, Ward DM, Warnes G, Watada H, Watanabe Y, Watase K, Weaver TE, Weekes CD, Wei J, Weide T, Weihl CC, Weindl G, Weis SN, Wen L, Wen X, Wen Y, Westermann B, Weyand CM, White AR, White E, Whitton JL, Whitworth AJ, Wiels J, Wild F, Wildenberg ME, Wileman T, Wilkinson DS, Wilkinson S, Willbold D, Williams C, Williams K, Williamson PR, Winklhofer KF, Witkin SS, Wohlgemuth SE, Wollert T, Wolvetang EJ, Wong E, Wong GW, Wong RW, Wong VK, Woodcock EA, Wright KL, Wu C, Wu D, Wu GS, Wu J, Wu J, Wu M, Wu M, Wu S, Wu WK, Wu Y, Wu Z, Xavier CP, Xavier RJ, Xia GX, Xia T, Xia W, Xia Y, Xiao H, Xiao J, Xiao S, Xiao W, Xie CM, Xie Z, Xie Z, Xilouri M, Xiong Y, Xu C, Xu C, Xu F, Xu H, Xu H, Xu J, Xu J, Xu J, Xu L, Xu X, Xu Y, Xu Y, Xu ZX, Xu Z, Xue Y, Yamada T, Yamamoto A, Yamanaka K, Yamashina S, Yamashiro S, Yan B, Yan B, Yan X, Yan Z, Yanagi Y, Yang DS, Yang JM, Yang L, Yang M, Yang PM, Yang P, Yang Q, Yang W, Yang WY, Yang X, Yang Y, Yang Y, Yang Z, Yang Z, Yao MC, Yao PJ, Yao X, Yao Z, Yao Z, Yasui LS, Ye M, Yedvobnick B, Yeganeh B, Yeh ES, Yeyati PL, Yi F, Yi L, Yin XM, Yip CK, Yoo YM, Yoo YH, Yoon SY, Yoshida K, Yoshimori T, Young KH, Yu H, Yu JJ, Yu JT, Yu J, Yu L, Yu WH, Yu XF, Yu Z, Yuan J, Yuan ZM, Yue BY, Yue J, Yue Z, Zacks DN, Zacksenhaus E, Zaffaroni N, Zaglia T, Zakeri Z, Zecchini V, Zeng J, Zeng M, Zeng Q, Zervos AS, Zhang DD, Zhang F, Zhang G, Zhang GC, Zhang H, Zhang H, Zhang H, Zhang H, Zhang J, Zhang J, Zhang J, Zhang J, Zhang JP, Zhang L, Zhang L, Zhang L, Zhang L, Zhang MY, Zhang X, Zhang XD, Zhang Y, Zhang Y, Zhang Y, Zhang Y, Zhang Y, Zhao M, Zhao WL, Zhao X, Zhao YG, Zhao Y, Zhao Y, Zhao YX, Zhao Z, Zhao ZJ, Zheng D, Zheng XL, Zheng X, Zhivotovsky B, Zhong Q, Zhou GZ, Zhou G, Zhou H, Zhou SF, Zhou XJ, Zhu H, Zhu H, Zhu WG, Zhu W, Zhu XF, Zhu Y, Zhuang SM, Zhuang X, Ziparo E, Zois CE, Zoladek T, Zong WX, Zorzano A, Zughaier SM: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 2016. PMID: 26799652

Yi S, Chen S, Zhang L, Sahni N: Signal Transduction and Regulation: Insights into Evolution. Biomed Res Int. 2016; 2016 Jul 20. PMID: 27525280

Chen PY, Simons M: Future Targets in Endothelial Biology: Endothelial Cell to Mesenchymal Transition. Curr Drug Targets. 2016. PMID: 27138761

Stutz B, Horvath TL: Synaptic lipids in cortical function and psychiatric disorders. EMBO Mol Med. 2016 Jan 1. PMID: 26671988

Cuttano R, Rudini N, Bravi L, Corada M, Giampietro C, Papa E, Morini MF, Maddaluno L, Baeyens N, Adams RH, Jain MK, Owens GK, Schwartz M, Lampugnani MG, Dejana E: KLF4 is a key determinant in the development and progression of cerebral cavernous malformations. EMBO Mol Med. 2016 Jan 1. PMID: 26612856

Yang CR, Lowther KM, Lalioti MD, Seli E: Embryonic Poly(A)-Binding Protein (EPAB) Is Required for Granulosa Cell EGF Signaling and Cumulus Expansion in Female Mice. Endocrinology. 2016 Jan; 2015 Oct 22. PMID: 26492470

Abou Zahr A, Bernabe Ramirez C, Wozney J, Prebet T, Zeidan AM: New Insights into the Pathogenesis of MDS and the rational therapeutic opportunities. Expert Rev Hematol. 2016; 2016 Feb 15. PMID: 26734762

Vannuccini S, Clifton VL, Fraser IS, Taylor HS, Critchley H, Giudice LC, Petraglia F: Infertility and reproductive disorders: impact of hormonal and inflammatory mechanisms on pregnancy outcome. Hum Reprod Update. 2016 Jan-Feb; 2015 Sep 22. PMID: 26395640

Pearson JA, Wong FS, Wen L: The importance of the Non Obese Diabetic (NOD) mouse model in autoimmune diabetes. J Autoimmun. 2016 Jan; 2015 Sep 26. PMID: 26403950

Yoon CM, Nam M, Oh YM, Dela Cruz CS, Kang MJ: Mitochondrial Regulation of Inflammasome Activation in Chronic Obstructive Pulmonary Disease. J Innate Immun. 2016; 2015 Nov 5. PMID: 26536345

Kahle KT, Delpire E: Kinase-KCC2 coupling: Cl- rheostasis, disease susceptibility, therapeutic target. J Neurophysiol. 2016 Jan 1; 2015 Oct 28. PMID: 26510764

Seleznik G, Seeger H, Bauer J, Fu K, Czerkowicz J, Papandile A, Poreci U, Rabah D, Ranger A, Cohen CD, Lindenmeyer M, Chen J, Edenhofer I, Anders HJ, Lech M, Wüthrich RP, Ruddle NH, Moeller MJ, Kozakowski N, Regele H, Browning JL, Heikenwalder M, Segerer S: The lymphotoxin β receptor is a potential therapeutic target in renal inflammation. Kidney Int. 2016 Jan; 2016 Jan 4. PMID: 26398497

Miller CJ, Turk BE: Rapid Identification of Protein Kinase Phosphorylation Site Motifs Using Combinatorial Peptide Libraries. Methods Mol Biol. 2016. PMID: 26501912

Deng Y, Turk BE: Analysis of Protein Tyrosine Kinase Specificity Using Positional Scanning Peptide Microarrays. Methods Mol Biol. 2016. PMID: 26490465

Baeyens N, Schwartz MA: Biomechanics of vascular mechanosensation and remodeling. Mol Biol Cell. 2016 Jan 1. PMID: 26715421

Streiter S, Fisch B, Sabbah B, Ao A, Abir R: The importance of neuronal growth factors in the ovary. Mol Hum Reprod. 2016 Jan; 2015 Oct 20. PMID: 26487421

Kamceva M, Benedict J, Nairn AC, Lombroso PJ: Role of Striatal-Enriched Tyrosine Phosphatase in Neuronal Function. Neural Plast. 2016; 2016 Apr 12. PMID: 27190655

Zheutlin AB, Viehman RW, Fortgang R, Borg J, Smith DJ, Suvisaari J, Therman S, Hultman CM, Cannon TD: Cognitive endophenotypes inform genome-wide expression profiling in schizophrenia. Neuropsychology. 2016 Jan. PMID: 26710095

Singh S, Arcaroli JJ, Orlicky DJ, Chen Y, Messersmith WA, Bagby S, Purkey A, Quackenbush KS, Thompson DC, Vasiliou V: Aldehyde Dehydrogenase 1B1 as a Modulator of Pancreatic Adenocarcinoma. Pancreas. 2016 Jan. PMID: 26566217

Pellowe AS, Gonzalez AL: Extracellular matrix biomimicry for the creation of investigational and therapeutic devices. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Jan-Feb; 2015 Jun 6. PMID: 26053111

Miller JC, Chezem WR, Clay NK: Ternary WD40 Repeat-Containing Protein Complexes: Evolution, Composition and Roles in Plant Immunity. Front Plant Sci. 2015; 2016 Jan 7. PMID: 26779203

Lee HJ, Bao J, Miller A, Zhang C, Wu J, Baday YC, Guibao C, Li L, Wu D, Zheng JJ: Structure-based Discovery of Novel Small Molecule Wnt Signaling Inhibitors by Targeting the Cysteine-rich Domain of Frizzled. J Biol Chem. 2015 Dec 18; 2015 Oct 26. PMID: 26504084

Xu RH, Wong EB, Rubio D, Roscoe F, Ma X, Nair S, Remakus S, Schwendener R, John S, Shlomchik M, Sigal LJ: Sequential Activation of Two Pathogen-Sensing Pathways Required for Type I Interferon Expression and Resistance to an Acute DNA Virus Infection. Immunity. 2015 Dec 15. PMID: 26682986

Garcia-Martinez I, Shaker ME, Mehal WZ: Therapeutic Opportunities in Damage-Associated Molecular Pattern-Driven Metabolic Diseases. Antioxid Redox Signal. 2015 Dec 10; 2015 Jul 27. PMID: 26055926

Teng R, Hu Y, Zhou J, Seifer B, Chen Y, Shen J, Wang L: Overexpression of Lin28 Decreases the Chemosensitivity of Gastric Cancer Cells to Oxaliplatin, Paclitaxel, Doxorubicin, and Fluorouracil in Part via microRNA-107. PLoS One. 2015; 2015 Dec 4. PMID: 26636340

Nowarski R, Jackson R, Gagliani N, de Zoete MR, Palm NW, Bailis W, Low JS, Harman CC, Graham M, Elinav E, Flavell RA: Epithelial IL-18 Equilibrium Controls Barrier Function in Colitis. Cell. 2015 Dec 3. PMID: 26638073

Levy M, Thaiss CA, Zeevi D, Dohnalová L, Zilberman-Schapira G, Mahdi JA, David E, Savidor A, Korem T, Herzig Y, Pevsner-Fischer M, Shapiro H, Christ A, Harmelin A, Halpern Z, Latz E, Flavell RA, Amit I, Segal E, Elinav E: Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling. Cell. 2015 Dec 3. PMID: 26638072

McKay SE, Yan W, Nouws J, Thormann MJ, Raimundo N, Khan A, Santos-Sacchi J, Song L, Shadel GS: Auditory Pathology in a Transgenic mtTFB1 Mouse Model of Mitochondrial Deafness. Am J Pathol. 2015 Dec; 2015 Nov 6. PMID: 26552864

Mueller M, Schoeberlein A, Zhou J, Joerger-Messerli M, Oppliger B, Reinhart U, Bordey A, Surbek D, Barnea ER, Huang Y, Paidas M: PreImplantation Factor bolsters neuroprotection via modulating Protein Kinase A and Protein Kinase C signaling. Cell Death Differ. 2015 Dec; 2015 May 15. PMID: 25976303

Gassié L, Lombard A, Moraldi T, Bibonne A, Leclerc C, Moreau M, Marlier A, Gilbert T: Hspa9 is required for pronephros specification and formation in Xenopus laevis. Dev Dyn. 2015 Dec; 2015 Sep 23. PMID: 26335666

Endicott SJ, Basu B, Khokha M, Brueckner M: The NIMA-like kinase Nek2 is a key switch balancing cilia biogenesis and resorption in the development of left-right asymmetry. Development. 2015 Dec 1; 2015 Oct 22. PMID: 26493400

Finethy R, Jorgensen I, Haldar AK, de Zoete MR, Strowig T, Flavell RA, Yamamoto M, Nagarajan UM, Miao EA, Coers J: Guanylate binding proteins enable rapid activation of canonical and noncanonical inflammasomes in Chlamydia-infected macrophages. Infect Immun. 2015 Dec; 2015 Sep 28. PMID: 26416908

Brodeur TY, Robidoux TE, Weinstein JS, Craft J, Swain SL, Marshak-Rothstein A: IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells. J Immunol. 2015 Dec 1; 2015 Oct 30. PMID: 26519529

Montgomery RR, Shaw AC: Paradoxical changes in innate immunity in aging: recent progress and new directions. J Leukoc Biol. 2015 Dec; 2015 Jul 17. PMID: 26188078

Lu J, Lee-Gabel L, Nadeau MC, Ferencz TM, Soefje SA: Clinical evaluation of compounds targeting PD-1/PD-L1 pathway for cancer immunotherapy. J Oncol Pharm Pract. 2015 Dec; 2014 Jun 9. PMID: 24917416

Huang Y, Ma SF, Vij R, Oldham JM, Herazo-Maya J, Broderick SM, Strek ME, White SR, Hogarth DK, Sandbo NK, Lussier YA, Gibson KF, Kaminski N, Garcia JG, Noth I: A functional genomic model for predicting prognosis in idiopathic pulmonary fibrosis. BMC Pulm Med. 2015 Nov 21; 2015 Nov 21. PMID: 26589497

Cheung WK, Nguyen DX: Lineage factors and differentiation states in lung cancer progression. Oncogene. 2015 Nov 19; 2015 Mar 30. PMID: 25823023

Cho RW, Buhl LK, Volfson D, Tran A, Li F, Akbergenova Y, Littleton JT: Phosphorylation of Complexin by PKA Regulates Activity-Dependent Spontaneous Neurotransmitter Release and Structural Synaptic Plasticity. Neuron. 2015 Nov 18. PMID: 26590346

Tan Y, Zanoni I, Cullen TW, Goodman AL, Kagan JC: Mechanisms of Toll-like Receptor 4 Endocytosis Reveal a Common Immune-Evasion Strategy Used by Pathogenic and Commensal Bacteria. Immunity. 2015 Nov 17; 2015 Nov 3. PMID: 26546281

Shi H, Gatzke F, Molle JM, Lee HB, Helm ET, Oldham JJ, Zhang L, Gerrard DE, Bennett AM: Mice lacking MKP-1 and MKP-5 Reveal Hierarchical Regulation of Regenerative Myogenesis. J Stem Cell Regen Biol. 2015 Nov 12. PMID: 27064463

Lau E, Sedy J, Sander C, Shaw MA, Feng Y, Scortegagna M, Claps G, Robinson S, Cheng P, Srivas R, Soonthornvacharin S, Ideker T, Bosenberg M, Gonzalez R, Robinson W, Chanda SK, Ware C, Dummer R, Hoon D, Kirkwood JM, Ronai ZA: Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy. Oncogene. 2015 Nov 12; 2015 Mar 2. PMID: 25728676

Langdon CG, Wiedemann N, Held MA, Mamillapalli R, Iyidogan P, Theodosakis N, Platt JT, Levy F, Vuagniaux G, Wang S, Bosenberg MW, Stern DF: SMAC mimetic Debio 1143 synergizes with taxanes, topoisomerase inhibitors and bromodomain inhibitors to impede growth of lung adenocarcinoma cells. Oncotarget. 2015 Nov 10. PMID: 26485762

Guetta-Terrier C, Monzo P, Zhu J, Long H, Venkatraman L, Zhou Y, Wang P, Chew SY, Mogilner A, Ladoux B, Gauthier NC: Protrusive waves guide 3D cell migration along nanofibers. J Cell Biol. 2015 Nov 9. PMID: 26553933

Zhou J, Qin L, Yi T, Ali R, Li Q, Jiao Y, Li G, Tobiasova Z, Huang Y, Zhang J, Yun JJ, Sadeghi MM, Giordano FJ, Pober JS, Tellides G: Interferon-γ-mediated allograft rejection exacerbates cardiovascular disease of hyperlipidemic murine transplant recipients. Circ Res. 2015 Nov 6; 2015 Sep 23. PMID: 26399469

Su H, Li J, Zhang H, Ma W, Wei N, Liu J, Wang X: COP9 signalosome controls the degradation of cytosolic misfolded proteins and protects against cardiac proteotoxicity. Circ Res. 2015 Nov 6; 2015 Sep 17. PMID: 26383969

Culhane KJ, Liu Y, Cai Y, Yan EC: Transmembrane signal transduction by peptide hormones via family B G protein-coupled receptors. Front Pharmacol. 2015; 2015 Nov 5. PMID: 26594176

Carter DR, Murray J, Cheung BB, Gamble L, Koach J, Tsang J, Sutton S, Kalla H, Syed S, Gifford AJ, Issaeva N, Biktasova A, Atmadibrata B, Sun Y, Sokolowski N, Ling D, Kim PY, Webber H, Clark A, Ruhle M, Liu B, Oberthuer A, Fischer M, Byrne J, Saletta F, Thwe le M, Purmal A, Haderski G, Burkhart C, Speleman F, De Preter K, Beckers A, Ziegler DS, Liu T, Gurova KV, Gudkov AV, Norris MD, Haber M, Marshall GM: Therapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma. Sci Transl Med. 2015 Nov 4. PMID: 26537256

Young RM, Wu T, Schmitz R, Dawood M, Xiao W, Phelan JD, Xu W, Menard L, Meffre E, Chan WC, Jaffe ES, Gascoyne RD, Campo E, Rosenwald A, Ott G, Delabie J, Rimsza LM, Staudt LM: Survival of human lymphoma cells requires B-cell receptor engagement by self-antigens. Proc Natl Acad Sci U S A. 2015 Nov 3; 2015 Oct 19. PMID: 26483459

Yamagata Y, Nairn AC: Contrasting features of ERK1/2 activity and synapsin I phosphorylation at the ERK1/2-dependent site in the rat brain in status epilepticus induced by kainic acid in vivo. Brain Res. 2015 Nov 2; 2015 Aug 28. PMID: 26320550

Bauer Y, Nayler O, Kaminski N: Reply: the bleomycin model: in pursuit of relevant biomakers. Am J Respir Cell Mol Biol. 2015 Nov. PMID: 26517754

Alves DS, Thulin G, Loffing J, Kashgarian M, Caplan MJ: Akt Substrate of 160 kD Regulates Na+,K+-ATPase Trafficking in Response to Energy Depletion and Renal Ischemia. J Am Soc Nephrol. 2015 Nov; 2015 Mar 18. PMID: 25788531

Marzuka A, Huang L, Theodosakis N, Bosenberg M: Melanoma Treatments: Advances and Mechanisms. J Cell Physiol. 2015 Nov. PMID: 25899612

Griesi-Oliveira K, Acab A, Gupta AR, Sunaga DY, Chailangkarn T, Nicol X, Nunez Y, Walker MF, Murdoch JD, Sanders SJ, Fernandez TV, Ji W, Lifton RP, Vadasz E, Dietrich A, Pradhan D, Song H, Ming GL, Gu X, Haddad G, Marchetto MC, Spitzer N, Passos-Bueno MR, State MW, Muotri AR: Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. Mol Psychiatry. 2015 Nov; 2014 Nov 11. PMID: 25385366

Lin R, Elf S, Shan C, Kang HB, Ji Q, Zhou L, Hitosugi T, Zhang L, Zhang S, Seo JH, Xie J, Tucker M, Gu TL, Sudderth J, Jiang L, Mitsche M, DeBerardinis RJ, Wu S, Li Y, Mao H, Chen PR, Wang D, Chen GZ, Hurwitz SJ, Lonial S, Arellano ML, Khoury HJ, Khuri FR, Lee BH, Lei Q, Brat DJ, Ye K, Boggon TJ, He C, Kang S, Fan J, Chen J: 6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling. Nat Cell Biol. 2015 Nov; 2015 Oct 19. PMID: 26479318

Goedeke L, Rotllan N, Canfrán-Duque A, Aranda JF, Ramírez CM, Araldi E, Lin CS, Anderson NN, Wagschal A, de Cabo R, Horton JD, Lasunción MA, Näär AM, Suárez Y, Fernández-Hernando C: MicroRNA-148a regulates LDL receptor and ABCA1 expression to control circulating lipoprotein levels. Nat Med. 2015 Nov; 2015 Oct 5. PMID: 26437365

Kannurpatti SS, Sanganahalli BG, Herman P, Hyder F: Role of mitochondrial calcium uptake homeostasis in resting state fMRI brain networks. NMR Biomed. 2015 Nov; 2015 Oct 6. PMID: 26439799

Gisslen T, Ennis K, Bhandari V, Rao R: Recurrent hypoinsulinemic hyperglycemia in neonatal rats increases PARP-1 and NF-κB expression and leads to microglial activation in the cerebral cortex. Pediatr Res. 2015 Nov; 2015 Jul 22. PMID: 26200703

Gagliani N, Battaglia M: All in (IL-) 1? Transplantation. 2015 Nov. PMID: 26492049

Licznerski P, Duric V, Banasr M, Alavian KN, Ota KT, Kang HJ, Jonas EA, Ursano R, Krystal JH, Duman RS, Traumatic Stress Brain Study Group.: Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress. PLoS Biol. 2015 Oct; 2015 Oct 27. PMID: 26506154

Shadel GS, Horvath TL: Mitochondrial ROS signaling in organismal homeostasis. Cell. 2015 Oct 22; 2015 Oct 22. PMID: 26496603

Ray JP, Staron MM, Shyer JA, Ho PC, Marshall HD, Gray SM, Laidlaw BJ, Araki K, Ahmed R, Kaech SM, Craft J: The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Immunity. 2015 Oct 20; 2015 Sep 22. PMID: 26410627

Chen Y, Gou X, Kong DK, Wang X, Wang J, Chen Z, Huang C, Zhou J: EMMPRIN regulates tumor growth and metastasis by recruiting bone marrow-derived cells through paracrine signaling of SDF-1 and VEGF. Oncotarget. 2015 Oct 20. PMID: 26416452

Li X, Fisher OS, Boggon TJ: The cerebral cavernous malformations proteins. Oncotarget. 2015 Oct 20. PMID: 26356566

Jha A, Singh AK, Weissgerber P, Freichel M, Flockerzi V, Flavell RA, Jha MK: Essential roles for Cavβ2 and Cav1 channels in thymocyte development and T cell homeostasis. Sci Signal. 2015 Oct 20; 2015 Oct 20. PMID: 26486172

Nevius E, Pinho F, Dhodapkar M, Jin H, Nadrah K, Horowitz MC, Kikuta J, Ishii M, Pereira JP: Oxysterols and EBI2 promote osteoclast precursor migration to bone surfaces and regulate bone mass homeostasis. J Exp Med. 2015 Oct 19; 2015 Oct 5. PMID: 26438360

Strout MP: Sugar-coated signaling in follicular lymphoma. Blood. 2015 Oct 15. PMID: 26472734

Gong X, Zhang L, Huang T, Lin TV, Miyares L, Wen J, Hsieh L, Bordey A: Activating the translational repressor 4E-BP or reducing S6K-GSK3β activity prevents accelerated axon growth induced by hyperactive mTOR in vivo. Hum Mol Genet. 2015 Oct 15; 2015 Jul 28. PMID: 26220974

Lascano J, Uchil PD, Mothes W, Luban J: TRIM5 Retroviral Restriction Activity Correlates with the Ability To Induce Innate Immune Signaling. J Virol. 2015 Oct 14; 2015 Oct 14. PMID: 26468522

Landskroner-Eiger S, Qiu C, Perrotta P, Siragusa M, Lee MY, Ulrich V, Luciano AK, Zhuang ZW, Corti F, Simons M, Montgomery RL, Wu D, Yu J, Sessa WC: Endothelial miR-17∼92 cluster negatively regulates arteriogenesis via miRNA-19 repression of WNT signaling. Proc Natl Acad Sci U S A. 2015 Oct 13; 2015 Sep 28. PMID: 26417068

Phinney DG, Di Giuseppe M, Njah J, Sala E, Shiva S, St Croix CM, Stolz DB, Watkins SC, Di YP, Leikauf GD, Kolls J, Riches DW, Deiuliis G, Kaminski N, Boregowda SV, McKenna DH, Ortiz LA: Mesenchymal stem cells use extracellular vesicles to outsource mitophagy and shuttle microRNAs. Nat Commun. 2015 Oct 7; 2015 Oct 7. PMID: 26442449

Lee BK, Shen W, Lee J, Rhee C, Chung H, Kim KY, Park IH, Kim J: Tgif1 Counterbalances the Activity of Core Pluripotency Factors in Mouse Embryonic Stem Cells. Cell Rep. 2015 Oct 6; 2015 Sep 24. PMID: 26411691

Kim JG, Sun BH, Dietrich MO, Koch M, Yao GQ, Diano S, Insogna K, Horvath TL: AgRP Neurons Regulate Bone Mass. Cell Rep. 2015 Oct 6; 2015 Sep 24. PMID: 26411686

Bacaj T, Wu D, Burré J, Malenka RC, Liu X, Südhof TC: Synaptotagmin-1 and -7 Are Redundantly Essential for Maintaining the Capacity of the Readily-Releasable Pool of Synaptic Vesicles. PLoS Biol. 2015 Oct; 2015 Oct 5. PMID: 26437117

Kim GE, Ross JL, Xie C, Su KN, Zaha VG, Wu X, Palmeri M, Ashraf M, Akar JG, Russell KS, Akar FG, Young LH: LKB1 deletion causes early changes in atrial channel expression and electrophysiology prior to atrial fibrillation. Cardiovasc Res. 2015 Oct 1. PMID: 26378152

Kobashigawa Y, Amano S, Yokogawa M, Kumeta H, Morioka H, Inouye M, Schlessinger J, Inagaki F: Structural analysis of the mechanism of phosphorylation of a critical autoregulatory tyrosine residue in FGFR1 kinase domain. Genes Cells. 2015 Oct; 2015 Aug 24. PMID: 26300540

Li S, Pinard M, Wang Y, Yang L, Lin R, Hiscott J, Su B, Brodt P: Crosstalk between the TNF and IGF pathways enhances NF-κB activation and signaling in cancer cells. Growth Horm IGF Res. 2015 Oct; 2015 Jul 20. PMID: 26239406

Hartmann BM, Thakar J, Albrecht RA, Avey S, Zaslavsky E, Marjanovic N, Chikina M, Fribourg M, Hayot F, Schmolke M, Meng H, Wetmur J, García-Sastre A, Kleinstein SH, Sealfon SC: Human Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses. J Virol. 2015 Oct; 2015 Jul 29. PMID: 26223639

Sati L, Zeiss C, Yekkala K, Demir R, McGrath J: Expression of the CTCFL Gene during Mouse Embryogenesis Causes Growth Retardation, Postnatal Lethality, and Dysregulation of the Transforming Growth Factor β Pathway. Mol Cell Biol. 2015 Oct; 2015 Jul 13. PMID: 26169830

Mandal M, Hamel KM, Maienschein-Cline M, Tanaka A, Teng G, Tuteja JH, Bunker JJ, Bahroos N, Eppig JJ, Schatz DG, Clark MR: Histone reader BRWD1 targets and restricts recombination to the Igk locus. Nat Immunol. 2015 Oct; 2015 Aug 24. PMID: 26301565

Medzhitov R: Bringing Warburg to lymphocytes. Nat Rev Immunol. 2015 Oct. PMID: 26403193

Navarria A, Wohleb ES, Voleti B, Ota KT, Dutheil S, Lepack AE, Dwyer JM, Fuchikami M, Becker A, Drago F, Duman RS: Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors. Neurobiol Dis. 2015 Oct; 2015 Jun 21. PMID: 26102021

Korpi ER, den Hollander B, Farooq U, Vashchinkina E, Rajkumar R, Nutt DJ, Hyytiä P, Dawe GS: Mechanisms of Action and Persistent Neuroplasticity by Drugs of Abuse. Pharmacol Rev. 2015 Oct. PMID: 26403687

Monteiro A, Tong X, Bear A, Liew SF, Bhardwaj S, Wasik BR, Dinwiddie A, Bastianelli C, Cheong WF, Wenk MR, Cao H, Prudic KL: Differential Expression of Ecdysone Receptor Leads to Variation in Phenotypic Plasticity across Serial Homologs. PLoS Genet. 2015; 2015 Sep 25. PMID: 26405828

Creixell P, Schoof EM, Simpson CD, Longden J, Miller CJ, Lou HJ, Perryman L, Cox TR, Zivanovic N, Palmeri A, Wesolowska-Andersen A, Helmer-Citterich M, Ferkinghoff-Borg J, Itamochi H, Bodenmiller B, Erler JT, Turk BE, Linding R: Kinome-wide decoding of network-attacking mutations rewiring cancer signaling. Cell. 2015 Sep 24; 2015 Sep 17. PMID: 26388441

Morton SD, Cadamuro M, Brivio S, Vismara M, Stecca T, Massani M, Bassi N, Furlanetto A, Joplin RE, Floreani A, Fabris L, Strazzabosco M: Leukemia inhibitory factor protects cholangiocarcinoma cells from drug-induced apoptosis via a PI3K/AKT-dependent Mcl-1 activation. Oncotarget. 2015 Sep 22. PMID: 26296968

Wu L, Chen X, Zhao J, Martin B, Zepp JA, Ko JS, Gu C, Cai G, Ouyang W, Sen G, Stark GR, Su B, Vines CM, Tournier C, Hamilton TA, Vidimos A, Gastman B, Liu C, Li X: A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis. J Exp Med. 2015 Sep 21; 2015 Sep 7. PMID: 26347473

Ningappa M, So J, Glessner J, Ashokkumar C, Ranganathan S, Min J, Higgs BW, Sun Q, Haberman K, Schmitt L, Vilarinho S, Mistry PK, Vockley G, Dhawan A, Gittes GK, Hakonarson H, Jaffe R, Subramaniam S, Shin D, Sindhi R: The Role of ARF6 in Biliary Atresia. PLoS One. 2015; 2015 Sep 17. PMID: 26379158

Rawling DC, Fitzgerald ME, Pyle AM: Establishing the role of ATP for the function of the RIG-I innate immune sensor. Elife. 2015 Sep 15; 2015 Sep 15. PMID: 26371557

Gorenshteyn D, Zaslavsky E, Fribourg M, Park CY, Wong AK, Tadych A, Hartmann BM, Albrecht RA, García-Sastre A, Kleinstein SH, Troyanskaya OG, Sealfon SC: Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases. Immunity. 2015 Sep 15; 2015 Sep 8. PMID: 26362267

Ho PC, Bihuniak JD, Macintyre AN, Staron M, Liu X, Amezquita R, Tsui YC, Cui G, Micevic G, Perales JC, Kleinstein SH, Abel ED, Insogna KL, Feske S, Locasale JW, Bosenberg MW, Rathmell JC, Kaech SM: Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses. Cell. 2015 Sep 10; 2015 Aug 27. PMID: 26321681

Hu C, Ding H, Li Y, Pearson JA, Zhang X, Flavell RA, Wong FS, Wen L: NLRP3 deficiency protects from type 1 diabetes through the regulation of chemotaxis into the pancreatic islets. Proc Natl Acad Sci U S A. 2015 Sep 8; 2015 Aug 24. PMID: 26305961

Idevall-Hagren O, Lü A, Xie B, De Camilli P: Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering. EMBO J. 2015 Sep 2; 2015 Jul 22. PMID: 26202220

Martín Sánchez C, Pérez Martín JM, Jin JS, Dávalos A, Zhang W, de la Peña G, Martínez-Botas J, Rodríguez-Acebes S, Suárez Y, Hazen MJ, Gómez-Coronado D, Busto R, Cheng YC, Lasunción MA: Disruption of the mevalonate pathway induces dNTP depletion and DNA damage. Biochim Biophys Acta. 2015 Sep; 2015 Jun 5. PMID: 26055626

Ji W, Li Y, He Y, Yin M, Zhou HJ, Boggon TJ, Zhang H, Min W: AIP1 Expression in Tumor Niche Suppresses Tumor Progression and Metastasis. Cancer Res. 2015 Sep 1; 2015 Jul 2. PMID: 26139244

Hayashi K, Sasai M, Iwasaki A: Toll-like receptor 9 trafficking and signaling for type I interferons requires PIKfyve activity. Int Immunol. 2015 Sep; 2015 Apr 29. PMID: 25925170

Antignac C, Calvet JP, Germino GG, Grantham JJ, Guay-Woodford LM, Harris PC, Hildebrandt F, Peters DJ, Somlo S, Torres VE, Walz G, Zhou J, Yu AS: The Future of Polycystic Kidney Disease Research--As Seen By the 12 Kaplan Awardees. J Am Soc Nephrol. 2015 Sep; 2015 May 7. PMID: 25952256

Bethel M, Barnes CL, Taylor AF, Cheng YH, Chitteti BR, Horowitz MC, Bruzzaniti A, Srour EF, Kacena MA: A novel role for thrombopoietin in regulating osteoclast development in humans and mice. J Cell Physiol. 2015 Sep. PMID: 25656774

Bárcena C, Stefanovic M, Tutusaus A, Joannas L, Menéndez A, García-Ruiz C, Sancho-Bru P, Marí M, Caballeria J, Rothlin CV, Fernández-Checa JC, de Frutos PG, Morales A: Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation. J Hepatol. 2015 Sep; 2015 Apr 20. PMID: 25908269

Yaniv Y, Ganesan A, Yang D, Ziman BD, Lyashkov AE, Levchenko A, Zhang J, Lakatta EG: Real-time relationship between PKA biochemical signal network dynamics and increased action potential firing rate in heart pacemaker cells: Kinetics of PKA activation in heart pacemaker cells. J Mol Cell Cardiol. 2015 Sep; 2015 Aug 1. PMID: 26241846

Ceglia I, Reitz C, Gresack J, Ahn JH, Bustos V, Bleck M, Zhang X, Martin G, Simon SM, Nairn AC, Greengard P, Kim Y: APP intracellular domain-WAVE1 pathway reduces amyloid-β production. Nat Med. 2015 Sep; 2015 Aug 17. PMID: 26280122

Qu L, Fu K, Yang J, Shimada SG, LaMotte RH: CXCR3 chemokine receptor signaling mediates itch in experimental allergic contact dermatitis. Pain. 2015 Sep. PMID: 25932692

Wei W, Wolf F, Wang XJ: Impact of membrane bistability on dynamical response of neuronal populations. Phys Rev E Stat Nonlin Soft Matter Phys. 2015 Sep; 2015 Sep 25. PMID: 26465517

Iijima N, Iwasaki A: Tissue instruction for migration and retention of TRM cells. Trends Immunol. 2015 Sep; 2015 Aug 14. PMID: 26282885

Uzhachenko R, Shanker A, Yarbrough WG, Ivanova AV: Mitochondria, calcium, and tumor suppressor Fus1: At the crossroad of cancer, inflammation, and autoimmunity. Oncotarget. 2015 Aug 28. PMID: 26246474

Wen JH, Wen H, Gibson-Corley KN, Glenn KA: FBG1 Is the Final Arbitrator of A1AT-Z Degradation. PLoS One. 2015; 2015 Aug 21. PMID: 26295339

Lahiri A, Hedl M, Abraham C: MTMR3 risk allele enhances innate receptor-induced signaling and cytokines by decreasing autophagy and increasing caspase-1 activation. Proc Natl Acad Sci U S A. 2015 Aug 18; 2015 Aug 3. PMID: 26240347

Siragusa M, Fröhlich F, Park EJ, Schleicher M, Walther TC, Sessa WC: Stromal cell-derived factor 2 is critical for Hsp90-dependent eNOS activation. Sci Signal. 2015 Aug 18; 2015 Aug 18. PMID: 26286023

Guo X, Wang SB, Xu H, Ribic A, Mohns EJ, Zhou Y, Zhu X, Biederer T, Crair MC, Chen B: A short N-terminal domain of HDAC4 preserves photoreceptors and restores visual function in retinitis pigmentosa. Nat Commun. 2015 Aug 14; 2015 Aug 14. PMID: 26272629

Nadrah K, Beck TC, Pereira JP: Immature B Cell Egress from Bone Marrow Is SOCS3 Independent. PLoS One. 2015; 2015 Aug 14. PMID: 26274929

Xiang Y, Kim KY, Gelernter J, Park IH, Zhang H: Ethanol upregulates NMDA receptor subunit gene expression in human embryonic stem cell-derived cortical neurons. PLoS One. 2015; 2015 Aug 12. PMID: 26266540

Qian H, Xu X, Niklason LE: Bmk-1 regulates lifespan in Caenorhabditis elegans by activating hsp-16. Oncotarget. 2015 Aug 7. PMID: 26299918

Vilborg A, Passarelli MC, Yario TA, Tycowski KT, Steitz JA: Widespread Inducible Transcription Downstream of Human Genes. Mol Cell. 2015 Aug 6; 2015 Jul 16. PMID: 26190259

Kang HB, Fan J, Lin R, Elf S, Ji Q, Zhao L, Jin L, Seo JH, Shan C, Arbiser JL, Cohen C, Brat D, Miziorko HM, Kim E, Abdel-Wahab O, Merghoub T, Fröhling S, Scholl C, Tamayo P, Barbie DA, Zhou L, Pollack BP, Fisher K, Kudchadkar RR, Lawson DH, Sica G, Rossi M, Lonial S, Khoury HJ, Khuri FR, Lee BH, Boggon TJ, He C, Kang S, Chen J: Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling. Mol Cell. 2015 Aug 6; 2015 Jul 2. PMID: 26145173

Pozo-Molina G, Ponciano-Gómez A, Rivera-González GC, Hernández-Zavala A, Garrido E: Arsenic-induced S phase cell cycle lengthening is associated with ROS generation, p53 signaling and CDC25A expression. Chem Biol Interact. 2015 Aug 5; 2015 Jul 3. PMID: 26148435

Jane-wit D, Surovtseva YV, Qin L, Li G, Liu R, Clark P, Manes TD, Wang C, Kashgarian M, Kirkiles-Smith NC, Tellides G, Pober JS: Complement membrane attack complexes activate noncanonical NF-κB by forming an Akt+ NIK+ signalosome on Rab5+ endosomes. Proc Natl Acad Sci U S A. 2015 Aug 4; 2015 Jul 20. PMID: 26195760

Fisher OS, Deng H, Liu D, Zhang Y, Wei R, Deng Y, Zhang F, Louvi A, Turk BE, Boggon TJ, Su B: Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex. Nat Commun. 2015 Aug 3; 2015 Aug 3. PMID: 26235885

Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y, Vijg J, Vinciguerra M, Fontana L: Interventions to Slow Aging in Humans: Are We Ready? Aging Cell. 2015 Aug; 2015 Apr 22. PMID: 25902704

Skoulidis F, Byers LA, Diao L, Papadimitrakopoulou VA, Tong P, Izzo J, Behrens C, Kadara H, Parra ER, Canales JR, Zhang J, Giri U, Gudikote J, Cortez MA, Yang C, Fan Y, Peyton M, Girard L, Coombes KR, Toniatti C, Heffernan TP, Choi M, Frampton GM, Miller V, Weinstein JN, Herbst RS, Wong KK, Zhang J, Sharma P, Mills GB, Hong WK, Minna JD, Allison JP, Futreal A, Wang J, Wistuba II, Heymach JV: Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities. Cancer Discov. 2015 Aug; 2015 Jun 11. PMID: 26069186

Ferguson SM: Beyond indigestion: emerging roles for lysosome-based signaling in human disease. Curr Opin Cell Biol. 2015 Aug; 2015 May 15. PMID: 25950843

Daley JM, Niu H, Miller AS, Sung P: Biochemical mechanism of DSB end resection and its regulation. DNA Repair (Amst). 2015 Aug; 2015 May 1. PMID: 25956866

Scanlon SE, Glazer PM: Multifaceted control of DNA repair pathways by the hypoxic tumor microenvironment. DNA Repair (Amst). 2015 Aug; 2015 May 1. PMID: 25956861

Kinch MS, Merkel J: An analysis of FDA-approved drugs for inflammation and autoimmune diseases. Drug Discov Today. 2015 Aug; 2015 Feb 17. PMID: 25701283

Ghazal S, McKinnon B, Zhou J, Mueller M, Men Y, Yang L, Mueller M, Flannery C, Huang Y, Taylor HS: H19 lncRNA alters stromal cell growth via IGF signaling in the endometrium of women with endometriosis. EMBO Mol Med. 2015 Aug. PMID: 26089099

Wang S, Song K, Srivastava R, Dong C, Go GW, Li N, Iwakiri Y, Mani A: Nonalcoholic fatty liver disease induced by noncanonical Wnt and its rescue by Wnt3a. FASEB J. 2015 Aug; 2015 Apr 27. PMID: 25917329

Xu J, Kurup P, Foscue E, Lombroso PJ: Striatal-enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathway. J Neurochem. 2015 Aug; 2015 May 25. PMID: 25951993

Plattner F, Hayashi K, Hernández A, Benavides DR, Tassin TC, Tan C, Day J, Fina MW, Yuen EY, Yan Z, Goldberg MS, Nairn AC, Greengard P, Nestler EJ, Taussig R, Nishi A, Houslay MD, Bibb JA: The role of ventral striatal cAMP signaling in stress-induced behaviors. Nat Neurosci. 2015 Aug; 2015 Jul 20. PMID: 26192746

Murrell M, Oakes PW, Lenz M, Gardel ML: Forcing cells into shape: the mechanics of actomyosin contractility. Nat Rev Mol Cell Biol. 2015 Aug; 2015 Jul 1. PMID: 26130009

Bielecki P, Jensen V, Schulze W, Gödeke J, Strehmel J, Eckweiler D, Nicolai T, Bielecka A, Wille T, Gerlach RG, Häussler S: Cross talk between the response regulators PhoB and TctD allows for the integration of diverse environmental signals in Pseudomonas aeruginosa. Nucleic Acids Res. 2015 Jul 27; 2015 Jun 16. PMID: 26082498

Konstantakou EG, Voutsinas GE, Velentzas AD, Basogianni AS, Paronis E, Balafas E, Kostomitsopoulos N, Syrigos KN, Anastasiadou E, Stravopodis DJ: 3-BrPA eliminates human bladder cancer cells with highly oncogenic signatures via engagement of specific death programs and perturbation of multiple signaling and metabolic determinants. Mol Cancer. 2015 Jul 22; 2015 Jul 22. PMID: 26198749

Gruber J, Chen CB, Fong S, Ng LF, Teo E, Halliwell B: Caenorhabditis elegans: What We Can and Cannot Learn from Aging Worms. Antioxid Redox Signal. 2015 Jul 20; 2015 Apr 29. PMID: 25544992

Egan DF, Chun MG, Vamos M, Zou H, Rong J, Miller CJ, Lou HJ, Raveendra-Panickar D, Yang CC, Sheffler DJ, Teriete P, Asara JM, Turk BE, Cosford ND, Shaw RJ: Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates. Mol Cell. 2015 Jul 16; 2015 Jun 25. PMID: 26118643

Salkoff DB, Zagha E, Yüzgeç Ö, McCormick DA: Synaptic Mechanisms of Tight Spike Synchrony at Gamma Frequency in Cerebral Cortex. J Neurosci. 2015 Jul 15. PMID: 26180200

Cox CM, Mandell EK, Stewart L, Lu R, Johnson DL, McCarter SD, Tavares A, Runyan R, Ghosh S, Wilson JM: Endosomal regulation of contact inhibition through the AMOT:YAP pathway. Mol Biol Cell. 2015 Jul 15; 2015 May 20. PMID: 25995376

Lur G, Higley MJ: Glutamate Receptor Modulation Is Restricted to Synaptic Microdomains. Cell Rep. 2015 Jul 14; 2015 Jul 2. PMID: 26146087

Migliore M, Cavarretta F, Marasco A, Tulumello E, Hines ML, Shepherd GM: Synaptic clusters function as odor operators in the olfactory bulb. Proc Natl Acad Sci U S A. 2015 Jul 7; 2015 Jun 22. PMID: 26100895

Kinch MS, Hoyer D, Patridge E, Plummer M: Target selection for FDA-approved medicines. Drug Discov Today. 2015 Jul; 2014 Nov 11. PMID: 25462532

Weerachayaphorn J, Amaya MJ, Spirli C, Chansela P, Mitchell-Richards KA, Ananthanarayanan M, Nathanson MH: Nuclear Factor, Erythroid 2-Like 2 Regulates Expression of Type 3 Inositol 1,4,5-Trisphosphate Receptor and Calcium Signaling in Cholangiocytes. Gastroenterology. 2015 Jul; 2015 Mar 18. PMID: 25796361

Wu C, Jia Y, Lee JH, Kim Y, Sekharan S, Batista VS, Lee SJ: Activation of OR1A1 suppresses PPAR-γ expression by inducing HES-1 in cultured hepatocytes. Int J Biochem Cell Biol. 2015 Jul; 2015 Mar 25. PMID: 25817041

Zheng S, Hedl M, Abraham C: Twist1 and Twist2 Contribute to Cytokine Downregulation following Chronic NOD2 Stimulation of Human Macrophages through the Coordinated Regulation of Transcriptional Repressors and Activators. J Immunol. 2015 Jul 1; 2015 May 27. PMID: 26019273

Huertas-Fernández I, Gómez-Garre P, Madruga-Garrido M, Bernal-Bernal I, Bonilla-Toribio M, Martín-Rodríguez JF, Cáceres-Redondo MT, Vargas-González L, Carrillo F, Pascual A, Tischfield JA, King RA, Heiman GA, Mir P: GDNF gene is associated with tourette syndrome in a family study. Mov Disord. 2015 Jul; 2015 Jun 12. PMID: 26096985

Samie M, Cresswell P: The transcription factor TFEB acts as a molecular switch that regulates exogenous antigen-presentation pathways. Nat Immunol. 2015 Jul; 2015 Jun 1. PMID: 26030023

Guerra MT, Nathanson MH: Calcium signaling and secretion in cholangiocytes. Pancreatology. 2015 Jul; 2015 Jun 12. PMID: 26100660

Langdon CG, Held MA, Platt JT, Meeth K, Iyidogan P, Mamillapalli R, Koo AB, Klein M, Liu Z, Bosenberg MW, Stern DF: The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors. Pigment Cell Melanoma Res. 2015 Jul; 2015 May 6. PMID: 25854919

Zhai K, Tang Y, Zhang Y, Li F, Wang Y, Cao Z, Yu J, Kou J, Yu B: NMMHC IIA inhibition impedes tissue factor expression and venous thrombosis via Akt/GSK3β-NF-κB signalling pathways in the endothelium. Thromb Haemost. 2015 Jul; 2015 Apr 16. PMID: 25881103

Yellman CM, Roeder GS: Cdc14 Early Anaphase Release, FEAR, Is Limited to the Nucleus and Dispensable for Efficient Mitotic Exit. PLoS One. 2015; 2015 Jun 19. PMID: 26090959

Doerner A, Scheck R, Schepartz A: Growth Factor Identity Is Encoded by Discrete Coiled-Coil Rotamers in the EGFR Juxtamembrane Region. Chem Biol. 2015 Jun 18. PMID: 26091170

Lu J, Qian Y, Altieri M, Dong H, Wang J, Raina K, Hines J, Winkler JD, Crew AP, Coleman K, Crews CM: Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4. Chem Biol. 2015 Jun 18; 2015 Jun 4. PMID: 26051217

Pedrozo Z, Criollo A, Battiprolu PK, Morales CR, Contreras-Ferrat A, Fernández C, Jiang N, Luo X, Caplan MJ, Somlo S, Rothermel BA, Gillette TG, Lavandero S, Hill JA: Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability. Circulation. 2015 Jun 16; 2015 Apr 17. PMID: 25888683

Xue Q, Lu Y, Eisele MR, Sulistijo ES, Khan N, Fan R, Miller-Jensen K: Analysis of single-cell cytokine secretion reveals a role for paracrine signaling in coordinating macrophage responses to TLR4 stimulation. Sci Signal. 2015 Jun 16; 2015 Jun 16. PMID: 26082435

Zhang Y, Nguyen T, Tang P, Kennedy NJ, Jiao H, Zhang M, Reynolds JM, Jaeschke A, Martin-Orozco N, Chung Y, He WM, Wang C, Jia W, Ge B, Davis RJ, Flavell RA, Dong C: Regulation of Adipose Tissue Inflammation and Insulin Resistance by MAPK Phosphatase 5. J Biol Chem. 2015 Jun 12; 2015 Apr 28. PMID: 25922079

Mehr S, Verdes A, DeSalle R, Sparks J, Pieribone V, Gruber DF: Transcriptome sequencing and annotation of the polychaete Hermodice carunculata (Annelida, Amphinomidae). BMC Genomics. 2015 Jun 10; 2015 Jun 10. PMID: 26059236

Housley WJ, Fernandez SD, Vera K, Murikinati SR, Grutzendler J, Cuerdon N, Glick L, De Jager PL, Mitrovic M, Cotsapas C, Hafler DA: Genetic variants associated with autoimmunity drive NFκB signaling and responses to inflammatory stimuli. Sci Transl Med. 2015 Jun 10. PMID: 26062845

Mesa KR, Rompolas P, Zito G, Myung P, Sun TY, Brown S, Gonzalez DG, Blagoev KB, Haberman AM, Greco V: Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool. Nature. 2015 Jun 4; 2015 Apr 6. PMID: 25849774

Yan L, Zhou J, Gao Y, Ghazal S, Lu L, Bellone S, Yang Y, Liu N, Zhao X, Santin AD, Taylor H, Huang Y: Regulation of tumor cell migration and invasion by the H19/let-7 axis is antagonized by metformin-induced DNA methylation. Oncogene. 2015 Jun 4; 2014 Aug 4. PMID: 25088204

Chun HJ, Yu PB: Elafin in pulmonary arterial hypertension. Beyond targeting elastases. Am J Respir Crit Care Med. 2015 Jun 1. PMID: 26029832

Kaufman AC, Salazar SV, Haas LT, Yang J, Kostylev MA, Jeng AT, Robinson SA, Gunther EC, van Dyck CH, Nygaard HB, Strittmatter SM: Fyn inhibition rescues established memory and synapse loss in Alzheimer mice. Ann Neurol. 2015 Jun; 2015 Mar 21. PMID: 25707991

Wang Y, Cao Y, Yamada S, Thirunavukkarasu M, Nin V, Joshi M, Rishi MT, Bhattacharya S, Camacho-Pereira J, Sharma AK, Shameer K, Kocher JP, Sanchez JA, Wang E, Hoeppner LH, Dutta SK, Leof EB, Shah V, Claffey KP, Chini EN, Simons M, Terzic A, Maulik N, Mukhopadhyay D: Cardiomyopathy and Worsened Ischemic Heart Failure in SM22-α Cre-Mediated Neuropilin-1 Null Mice: Dysregulation of PGC1α and Mitochondrial Homeostasis. Arterioscler Thromb Vasc Biol. 2015 Jun; 2015 Apr 16. PMID: 25882068

Idevall-Hagren O, De Camilli P: Detection and manipulation of phosphoinositides. Biochim Biophys Acta. 2015 Jun; 2014 Dec 13. PMID: 25514766

Lu L, Zeng H, Gu X, Ma W: Circulating tumor cell clusters-associated gene plakoglobin and breast cancer survival. Breast Cancer Res Treat. 2015 Jun; 2015 May 10. PMID: 25957595

Xu HP, Burbridge TJ, Chen MG, Ge X, Zhang Y, Zhou ZJ, Crair MC: Spatial pattern of spontaneous retinal waves instructs retinotopic map refinement more than activity frequency. Dev Neurobiol. 2015 Jun; 2015 Mar 30. PMID: 25787992

Srivastava A, Shinn AS, Lee PJ, Mannam P: MKK3 mediates inflammatory response through modulation of mitochondrial function. Free Radic Biol Med. 2015 Jun; 2015 Feb 17. PMID: 25697779

Huen SC, Huynh L, Marlier A, Lee Y, Moeckel GW, Cantley LG: GM-CSF Promotes Macrophage Alternative Activation after Renal Ischemia/Reperfusion Injury. J Am Soc Nephrol. 2015 Jun; 2014 Nov 11. PMID: 25388222

Han C, Yang Y, de Greef BT, Hoeijmakers JG, Gerrits MM, Verhamme C, Qu J, Lauria G, Merkies IS, Faber CG, Dib-Hajj SD, Waxman SG: The Domain II S4-S5 Linker in Nav1.9: A Missense Mutation Enhances Activation, Impairs Fast Inactivation, and Produces Human Painful Neuropathy. Neuromolecular Med. 2015 Jun; 2015 Mar 20. PMID: 25791876

Ha BH, Morse EM, Turk BE, Boggon TJ: Signaling, Regulation, and Specificity of the Type II p21-activated Kinases. J Biol Chem. 2015 May 22; 2015 Apr 8. PMID: 25855792

Dwyer JM, Maldonado-Avilés JG, Lepack AE, DiLeone RJ, Duman RS: Ribosomal protein S6 kinase 1 signaling in prefrontal cortex controls depressive behavior. Proc Natl Acad Sci U S A. 2015 May 12; 2015 Apr 27. PMID: 25918363

Kawabata S, Hollander MC, Munasinghe JP, Brinster LR, Mercado-Matos JR, Li J, Regales L, Pao W, Jänne PA, Wong KK, Butman JA, Lonser RR, Hansen MR, Gurgel RK, Vortmeyer AO, Dennis PA: Epidermal growth factor receptor as a novel molecular target for aggressive papillary tumors in the middle ear and temporal bone. Oncotarget. 2015 May 10. PMID: 26027747

Simons M, Eichmann A: Molecular controls of arterial morphogenesis. Circ Res. 2015 May 8. PMID: 25953926

Cui G, Staron MM, Gray SM, Ho PC, Amezquita RA, Wu J, Kaech SM: IL-7-Induced Glycerol Transport and TAG Synthesis Promotes Memory CD8+ T Cell Longevity. Cell. 2015 May 7. PMID: 25957683

Singh S, Arcaroli J, Chen Y, Thompson DC, Messersmith W, Jimeno A, Vasiliou V: ALDH1B1 Is Crucial for Colon Tumorigenesis by Modulating Wnt/β-Catenin, Notch and PI3K/Akt Signaling Pathways. PLoS One. 2015; 2015 May 7. PMID: 25950950

Wang'ondu R, Teal S, Park R, Heston L, Delecluse H, Miller G: DNA Damage Signaling Is Induced in the Absence of Epstein-Barr Virus (EBV) Lytic DNA Replication and in Response to Expression of ZEBRA. PLoS One. 2015; 2015 May 7. PMID: 25950714

Britto CJ, Cohn L: Bactericidal/Permeability-increasing protein fold-containing family member A1 in airway host protection and respiratory disease. Am J Respir Cell Mol Biol. 2015 May. PMID: 25265466

Zanini S, Giovinazzo F, Alaimo D, Lawrence B, Pfragner R, Bassi C, Modlin I, Kidd M: GNA15 expression in small intestinal neuroendocrine neoplasia: functional and signalling pathway analyses. Cell Signal. 2015 May; 2015 Feb 17. PMID: 25701539

Smuder AJ, Sollanek KJ, Min K, Nelson WB, Powers SK: Inhibition of forkhead boxO-specific transcription prevents mechanical ventilation-induced diaphragm dysfunction. Crit Care Med. 2015 May. PMID: 25746508

McCarthy TL, Centrella M: Prostaglandin dependent control of an endogenous estrogen receptor agonist by osteoblasts. J Cell Physiol. 2015 May. PMID: 25292157

Han C, Estacion M, Huang J, Vasylyev D, Zhao P, Dib-Hajj SD, Waxman SG: Human Na(v)1.8: enhanced persistent and ramp currents contribute to distinct firing properties of human DRG neurons. J Neurophysiol. 2015 May 1; 2015 Mar 18. PMID: 25787950

Rama N, Dubrac A, Mathivet T, Ní Chárthaigh RA, Genet G, Cristofaro B, Pibouin-Fragner L, Ma L, Eichmann A, Chédotal A: Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization. Nat Med. 2015 May; 2015 Apr 20. PMID: 25894826

Liu C, Lin Q, Yun Z: Cellular and molecular mechanisms underlying oxygen-dependent radiosensitivity. Radiat Res. 2015 May; 2015 May 4. PMID: 25938770

Wood CR, Rosenbaum JL: Ciliary ectosomes: transmissions from the cell's antenna. Trends Cell Biol. 2015 May; 2015 Jan 21. PMID: 25618328

Scholl UI, Stölting G, Nelson-Williams C, Vichot AA, Choi M, Loring E, Prasad ML, Goh G, Carling T, Juhlin CC, Quack I, Rump LC, Thiel A, Lande M, Frazier BG, Rasoulpour M, Bowlin DL, Sethna CB, Trachtman H, Fahlke C, Lifton RP: Recurrent gain of function mutation in calcium channel CACNA1H causes early-onset hypertension with primary aldosteronism. Elife. 2015 Apr 24; 2015 Apr 24. PMID: 25907736

Wang L, Velazquez H, Chang J, Safirstein R, Desir GV: Identification of a receptor for extracellular renalase. PLoS One. 2015; 2015 Apr 23. PMID: 25906147

Kumar V, Dasoveanu DC, Chyou S, Tzeng TC, Rozo C, Liang Y, Stohl W, Fu YX, Ruddle NH, Lu TT: A dendritic-cell-stromal axis maintains immune responses in lymph nodes. Immunity. 2015 Apr 21. PMID: 25902483

Yang Y, Keeler C, Kuo IY, Lolis EJ, Ehrlich BE, Hodsdon ME: Oligomerization of the polycystin-2 C-terminal tail and effects on its Ca2+-binding properties. J Biol Chem. 2015 Apr 17; 2015 Feb 25. PMID: 25716316

Obenauf AC, Zou Y, Ji AL, Vanharanta S, Shu W, Shi H, Kong X, Bosenberg MC, Wiesner T, Rosen N, Lo RS, Massagué J: Therapy-induced tumour secretomes promote resistance and tumour progression. Nature. 2015 Apr 16; 2015 Mar 25. PMID: 25807485

Hoque R, Mehal WZ: Inflammasomes in pancreatic physiology and disease. Am J Physiol Gastrointest Liver Physiol. 2015 Apr 15; 2015 Feb 19. PMID: 25700081

Nishimura S, Bilgüvar K, Ishigame K, Sestan N, Günel M, Louvi A: Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development. PLoS One. 2015; 2015 Apr 15. PMID: 25875176

Akin EJ, Solé L, Dib-Hajj SD, Waxman SG, Tamkun MM: Preferential targeting of Nav1.6 voltage-gated Na+ Channels to the axon initial segment during development. PLoS One. 2015; 2015 Apr 15. PMID: 25874799

Humphrey JD, Schwartz MA, Tellides G, Milewicz DM: Role of mechanotransduction in vascular biology: focus on thoracic aortic aneurysms and dissections. Circ Res. 2015 Apr 10. PMID: 25858068

Stites EC, Aziz M, Creamer MS, Von Hoff DD, Posner RG, Hlavacek WS: Use of mechanistic models to integrate and analyze multiple proteomic datasets. Biophys J. 2015 Apr 7. PMID: 25863072

Mannava AG, Tolwinski NS: Membrane bound GSK-3 activates Wnt signaling through disheveled and arrow. PLoS One. 2015; 2015 Apr 7. PMID: 25848770

Willinger T, Staron M, Ferguson SM, De Camilli P, Flavell RA: Dynamin 2-dependent endocytosis sustains T-cell receptor signaling and drives metabolic reprogramming in T lymphocytes. Proc Natl Acad Sci U S A. 2015 Apr 7; 2015 Mar 23. PMID: 25831514

Krishnakumar SS, Li F, Coleman J, Schauder CM, Kümmel D, Pincet F, Rothman JE, Reinisch KM: Re-visiting the trans insertion model for complexin clamping. Elife. 2015 Apr 2; 2015 Apr 2. PMID: 25831964

González-Fernández R, Ávila J, Arteaga MF, Canessa CM, Martín-Vasallo P: The neuronal-specific SGK1.1 (SGK1_v2) kinase as a transcriptional modulator of BAG4, Brox, and PPP1CB genes expression. Int J Mol Sci. 2015 Apr 2; 2015 Apr 2. PMID: 25849655

Yu DK, Zhang CX, Zhao SS, Zhang SH, Zhang H, Cai SY, Shao RG, He HW: The anti-fibrotic effects of epigallocatechin-3-gallate in bile duct-ligated cholestatic rats and human hepatic stellate LX-2 cells are mediated by the PI3K/Akt/Smad pathway. Acta Pharmacol Sin. 2015 Apr; 2015 Mar 16. PMID: 25832428

Ramana CV, DeBerge MP, Kumar A, Alia CS, Durbin JE, Enelow RI: Inflammatory impact of IFN-γ in CD8+ T cell-mediated lung injury is mediated by both Stat1-dependent and -independent pathways. Am J Physiol Lung Cell Mol Physiol. 2015 Apr 1; 2015 Jan 23. PMID: 25617378

Han B, Bellemer A, Koelle MR: An evolutionarily conserved switch in response to GABA affects development and behavior of the locomotor circuit of Caenorhabditis elegans. Genetics. 2015 Apr; 2015 Feb 2. PMID: 25644702

Kallakuri S, Yu JA, Li J, Li Y, Weinstein BM, Nicoli S, Sun Z: Endothelial cilia are essential for developmental vascular integrity in zebrafish. J Am Soc Nephrol. 2015 Apr; 2014 Sep 11. PMID: 25214579

Mohanty S, Joshi SR, Ueda I, Wilson J, Blevins TP, Siconolfi B, Meng H, Devine L, Raddassi K, Tsang S, Belshe RB, Hafler DA, Kaech SM, Kleinstein SH, Trentalange M, Allore HG, Shaw AC: Prolonged proinflammatory cytokine production in monocytes modulated by interleukin 10 after influenza vaccination in older adults. J Infect Dis. 2015 Apr 1; 2014 Nov 2. PMID: 25367297

Bindesbøll C, Fan Q, Nørgaard RC, MacPherson L, Ruan HB, Wu J, Pedersen TÅ, Steffensen KR, Yang X, Matthews J, Mandrup S, Nebb HI, Grønning-Wang LM: Liver X receptor regulates hepatic nuclear O-GlcNAc signaling and carbohydrate responsive element-binding protein activity. J Lipid Res. 2015 Apr; 2015 Feb 27. PMID: 25724563

Shields BJ, Alserihi R, Nasa C, Bogue C, Alexander WS, McCormack MP: Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2-transgenic mice. Leukemia. 2015 Apr; 2014 Oct 6. PMID: 25283843

Kim Y, Apetri M, Luo B, Settleman JE, Anderson KS: Differential Effects of Tyrosine Kinase Inhibitors on Normal and Oncogenic EGFR Signaling and Downstream Effectors. Mol Cancer Res. 2015 Apr; 2015 Jan 8. PMID: 25573954

Li K, Gao Z, He H, Terzaghi W, Fan LM, Deng XW, Chen H: Arabidopsis DET1 represses photomorphogenesis in part by negatively regulating DELLA protein abundance in darkness. Mol Plant. 2015 Apr; 2014 Dec 31. PMID: 25704163

Chen JH, Perry CJ, Tsui YC, Staron MM, Parish IA, Dominguez CX, Rosenberg DW, Kaech SM: Prostaglandin E2 and programmed cell death 1 signaling coordinately impair CTL function and survival during chronic viral infection. Nat Med. 2015 Apr; 2015 Mar 23. PMID: 25799228

Neymotin SA, McDougal RA, Sherif MA, Fall CP, Hines ML, Lytton WW: Neuronal calcium wave propagation varies with changes in endoplasmic reticulum parameters: a computer model. Neural Comput. 2015 Apr; 2015 Mar 3. PMID: 25734493

Kuenzel WJ, Kang SW, Zhou ZJ: Exploring avian deep-brain photoreceptors and their role in activating the neuroendocrine regulation of gonadal development. Poult Sci. 2015 Apr. PMID: 25828571

Ajani JA, Song S, Hochster HS, Steinberg IB: Cancer stem cells: the promise and the potential. Semin Oncol. 2015 Apr; 2015 Jan 21. PMID: 25839664

Coon BG, Baeyens N, Han J, Budatha M, Ross TD, Fang JS, Yun S, Thomas JL, Schwartz MA: Intramembrane binding of VE-cadherin to VEGFR2 and VEGFR3 assembles the endothelial mechanosensory complex. J Cell Biol. 2015 Mar 30; 2015 Mar 23. PMID: 25800053

Clark PR, Kim RK, Pober JS, Kluger MS: Tumor necrosis factor disrupts claudin-5 endothelial tight junction barriers in two distinct NF-κB-dependent phases. PLoS One. 2015; 2015 Mar 27. PMID: 25816133

Teichmann LL, Cullen JL, Kashgarian M, Dong C, Craft J, Shlomchik MJ: Local triggering of the ICOS coreceptor by CD11c(+) myeloid cells drives organ inflammation in lupus. Immunity. 2015 Mar 17. PMID: 25786178

Tornavaca O, Chia M, Dufton N, Almagro LO, Conway DE, Randi AM, Schwartz MA, Matter K, Balda MS: ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation. J Cell Biol. 2015 Mar 16; 2015 Mar 9. PMID: 25753039

Guo J, Yao H, Lin X, Xu H, Dean D, Zhu Z, Liu G, Sime P: IL-13 induces YY1 through the AKT pathway in lung fibroblasts. PLoS One. 2015; 2015 Mar 16. PMID: 25775215

Song X, Fan PD, Bantikassegn A, Guha U, Threadgill DW, Varmus H, Politi K: ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas. Cancer Res. 2015 Mar 15; 2015 Jan 16. PMID: 25596284

Jeon YJ, Khelifa S, Ratnikov B, Scott DA, Feng Y, Parisi F, Ruller C, Lau E, Kim H, Brill LM, Jiang T, Rimm DL, Cardiff RD, Mills GB, Smith JW, Osterman AL, Kluger Y, Ronai ZA: Regulation of glutamine carrier proteins by RNF5 determines breast cancer response to ER stress-inducing chemotherapies. Cancer Cell. 2015 Mar 9. PMID: 25759021

Shin H, Cox JA, Jarecki R, Starbuck A, Wang Z, Rakich PT: Control of coherent information via on-chip photonic-phononic emitter-receivers. Nat Commun. 2015 Mar 5; 2015 Mar 5. PMID: 25740405

Yuan S, Zhao L, Brueckner M, Sun Z: Intraciliary calcium oscillations initiate vertebrate left-right asymmetry. Curr Biol. 2015 Mar 2; 2015 Feb 5. PMID: 25660539

Kleppe M, Kwak M, Koppikar P, Riester M, Keller M, Bastian L, Hricik T, Bhagwat N, McKenney AS, Papalexi E, Abdel-Wahab O, Rampal R, Marubayashi S, Chen JJ, Romanet V, Fridman JS, Bromberg J, Teruya-Feldstein J, Murakami M, Radimerski T, Michor F, Fan R, Levine RL: JAK-STAT pathway activation in malignant and nonmalignant cells contributes to MPN pathogenesis and therapeutic response. Cancer Discov. 2015 Mar; 2015 Jan 8. PMID: 25572172

Perincheri S, Hui P: KRAS mutation testing in clinical practice. Expert Rev Mol Diagn. 2015 Mar; 2014 Dec 9. PMID: 25487540

Lee AW, Tyrer JP, Doherty JA, Stram DA, Kupryjanczyk J, Dansonka-Mieszkowska A, Plisiecka-Halasa J, Spiewankiewicz B, Myers EJ, Australian Cancer Study (Ovarian Cancer)., Australian Ovarian Cancer Study Group., Chenevix-Trench G, Fasching PA, Beckmann MW, Ekici AB, Hein A, Vergote I, Van Nieuwenhuysen E, Lambrechts D, Wicklund KG, Eilber U, Wang-Gohrke S, Chang-Claude J, Rudolph A, Sucheston-Campbell L, Odunsi K, Moysich KB, Shvetsov YB, Thompson PJ, Goodman MT, Wilkens LR, Dörk T, Hillemanns P, Dürst M, Runnebaum IB, Bogdanova N, Pelttari LM, Nevanlinna H, Leminen A, Edwards RP, Kelley JL, Harter P, Schwaab I, Heitz F, du Bois A, Orsulic S, Lester J, Walsh C, Karlan BY, Hogdall E, Kjaer SK, Jensen A, Vierkant RA, Cunningham JM, Goode EL, Fridley BL, Southey MC, Giles GG, Bruinsma F, Wu X, Hildebrandt MA, Lu K, Liang D, Bisogna M, Levine DA, Weber RP, Schildkraut JM, Iversen ES, Berchuck A, Terry KL, Cramer DW, Tworoger SS, Poole EM, Olson SH, Orlow I, Bandera EV, Bjorge L, Tangen IL, Salvesen HB, Krakstad C, Massuger LF, Kiemeney LA, Aben KK, van Altena AM, Bean Y, Pejovic T, Kellar M, Le ND, Cook LS, Kelemen LE, Brooks-Wilson A, Lubinski J, Gronwald J, Cybulski C, Jakubowska A, Wentzensen N, Brinton LA, Lissowska J, Yang H, Nedergaard L, Lundvall L, Hogdall C, Song H, Campbell IG, Eccles D, Glasspool R, Siddiqui N, Carty K, Paul J, McNeish IA, Sieh W, McGuire V, Rothstein JH, Whittemore AS, McLaughlin JR, Risch HA, Phelan CM, Anton-Culver H, Ziogas A, Menon U, Ramus SJ, Gentry-Maharaj A, Harrington P, Pike MC, Modugno F, Rossing MA, Ness RB, Pharoah PD, Stram DO, Wu AH, Pearce CL: Evaluating the ovarian cancer gonadotropin hypothesis: a candidate gene study. Gynecol Oncol. 2015 Mar; 2014 Dec 17. PMID: 25528498

Hu Y, Lee YT, Kaech SM, Garvy B, Cauley LS: Smad4 promotes differentiation of effector and circulating memory CD8 T cells but is dispensable for tissue-resident memory CD8 T cells. J Immunol. 2015 Mar 1; 2015 Jan 30. PMID: 25637015

McKay JT, Egan RP, Yammani RD, Chen L, Shin T, Yagita H, Haas KM: PD-1 suppresses protective immunity to Streptococcus pneumoniae through a B cell-intrinsic mechanism. J Immunol. 2015 Mar 1; 2015 Jan 26. PMID: 25624454

Surguchev A, Surguchov A: Effect of α-synuclein on membrane permeability and synaptic transmission: a clue to neurodegeneration? J Neurochem. 2015 Mar; 2015 Mar 4. PMID: 25739983

Moon HG, Qin Z, Quan T, Xie L, Dela Cruz CS, Jin Y: Matrix protein CCN1 induced by bacterial DNA and CpG ODN limits lung inflammation and contributes to innate immune homeostasis. Mucosal Immunol. 2015 Mar; 2014 Jul 9. PMID: 25005359

Han J, Calvo CF, Kang TH, Baker KL, Park JH, Parras C, Levittas M, Birba U, Pibouin-Fragner L, Fragner P, Bilguvar K, Duman RS, Nurmi H, Alitalo K, Eichmann AC, Thomas JL: Vascular endothelial growth factor receptor 3 controls neural stem cell activation in mice and humans. Cell Rep. 2015 Feb 24; 2015 Feb 19. PMID: 25704818

Yan EC, Wang Z, Fu L: Proteins at interfaces probed by chiral vibrational sum frequency generation spectroscopy. J Phys Chem B. 2015 Feb 19; 2015 Jan 21. PMID: 25565412

Kovalchuk Y, Homma R, Liang Y, Maslyukov A, Hermes M, Thestrup T, Griesbeck O, Ninkovic J, Cohen LB, Garaschuk O: In vivo odourant response properties of migrating adult-born neurons in the mouse olfactory bulb. Nat Commun. 2015 Feb 19; 2015 Feb 19. PMID: 25695931

Popa A, Zhang W, Harrison MS, Goodner K, Kazakov T, Goodwin EC, Lipovsky A, Burd CG, DiMaio D: Direct binding of retromer to human papillomavirus type 16 minor capsid protein L2 mediates endosome exit during viral infection. PLoS Pathog. 2015 Feb; 2015 Feb 18. PMID: 25693203

Burn KM, Shimada Y, Ayers K, Lu F, Hudson AM, Cooley L: Somatic insulin signaling regulates a germline starvation response in Drosophila egg chambers. Dev Biol. 2015 Feb 15; 2014 Dec 3. PMID: 25481758

Ye J, Shi H, Shen Y, Peng C, Liu Y, Li C, Deng K, Geng J, Xu T, Zhuang Y, Zheng B, Tao W: PP6 controls T cell development and homeostasis by negatively regulating distal TCR signaling. J Immunol. 2015 Feb 15; 2015 Jan 21. PMID: 25609840

Olson DK, Fröhlich F, Christiano R, Hannibal-Bach HK, Ejsing CS, Walther TC: Rom2-dependent phosphorylation of Elo2 controls the abundance of very long-chain fatty acids. J Biol Chem. 2015 Feb 13; 2014 Dec 17. PMID: 25519905

Su T, Bondar T, Zhou X, Zhang C, He H, Medzhitov R: Two-signal requirement for growth-promoting function of Yap in hepatocytes. Elife. 2015 Feb 10; 2015 Feb 10. PMID: 25667983

Zhang PX, Cheng J, Zou S, D'Souza AD, Koff JL, Lu J, Lee PJ, Krause DS, Egan ME, Bruscia EM: Pharmacological modulation of the AKT/microRNA-199a-5p/CAV1 pathway ameliorates cystic fibrosis lung hyper-inflammation. Nat Commun. 2015 Feb 10; 2015 Feb 10. PMID: 25665524

Perna D, Karreth FA, Rust AG, Perez-Mancera PA, Rashid M, Iorio F, Alifrangis C, Arends MJ, Bosenberg MW, Bollag G, Tuveson DA, Adams DJ: BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model. Proc Natl Acad Sci U S A. 2015 Feb 10; 2015 Jan 26. PMID: 25624498

Jin L, Li D, Alesi GN, Fan J, Kang HB, Lu Z, Boggon TJ, Jin P, Yi H, Wright ER, Duong D, Seyfried NT, Egnatchik R, DeBerardinis RJ, Magliocca KR, He C, Arellano ML, Khoury HJ, Shin DM, Khuri FR, Kang S: Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth. Cancer Cell. 2015 Feb 9. PMID: 25670081

Vidal SJ, Rodriguez-Bravo V, Quinn SA, Rodriguez-Barrueco R, Lujambio A, Williams E, Sun X, de la Iglesia-Vicente J, Lee A, Readhead B, Chen X, Galsky M, Esteve B, Petrylak DP, Dudley JT, Rabadan R, Silva JM, Hoshida Y, Lowe SW, Cordon-Cardo C, Domingo-Domenech J: A targetable GATA2-IGF2 axis confers aggressiveness in lethal prostate cancer. Cancer Cell. 2015 Feb 9. PMID: 25670080

Kuo IY, Ehrlich BE: Signaling in muscle contraction. Cold Spring Harb Perspect Biol. 2015 Feb 2; 2015 Feb 2. PMID: 25646377

Deng Y, Zhang X, Simons M: Molecular controls of lymphatic VEGFR3 signaling. Arterioscler Thromb Vasc Biol. 2015 Feb; 2014 Dec 18. PMID: 25524775

Peljto AL, Selman M, Kim DS, Murphy E, Tucker L, Pardo A, Lee JS, Ji W, Schwarz MI, Yang IV, Schwartz DA, Fingerlin TE: The MUC5B promoter polymorphism is associated with idiopathic pulmonary fibrosis in a Mexican cohort but is rare among Asian ancestries. Chest. 2015 Feb. PMID: 25275363

Martenson JS, Tomita S: Synaptic localization of neurotransmitter receptors: comparing mechanisms for AMPA and GABAA receptors. Curr Opin Pharmacol. 2015 Feb; 2014 Dec 17. PMID: 25529200

Lu X, Yarbrough WG: Negative regulation of RelA phosphorylation: emerging players and their roles in cancer. Cytokine Growth Factor Rev. 2015 Feb; 2014 Oct 2. PMID: 25438737

Huang J, Lin YC, Hileman S, Martin KH, Hull R, Yu HG: PP2 prevents isoproterenol stimulation of cardiac pacemaker activity. J Cardiovasc Pharmacol. 2015 Feb. PMID: 25658311

Das R, Verma R, Sznol M, Boddupalli CS, Gettinger SN, Kluger H, Callahan M, Wolchok JD, Halaban R, Dhodapkar MV, Dhodapkar KM: Combination therapy with anti-CTLA-4 and anti-PD-1 leads to distinct immunologic changes in vivo. J Immunol. 2015 Feb 1; 2014 Dec 24. PMID: 25539810

Moriguchi T, Sumpio BE: PECAM-1 phosphorylation and tissue factor expression in HUVECs exposed to uniform and disturbed pulsatile flow and chemical stimuli. J Vasc Surg. 2015 Feb; 2013 Dec 15. PMID: 24342062

Leiserson MD, Vandin F, Wu HT, Dobson JR, Eldridge JV, Thomas JL, Papoutsaki A, Kim Y, Niu B, McLellan M, Lawrence MS, Gonzalez-Perez A, Tamborero D, Cheng Y, Ryslik GA, Lopez-Bigas N, Getz G, Ding L, Raphael BJ: Pan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexes. Nat Genet. 2015 Feb; 2014 Dec 15. PMID: 25501392

Ray JP, Craft J: PTENtiating autoimmunity through Treg cell deregulation. Nat Immunol. 2015 Feb. PMID: 25594458

Singh JP, Zhang K, Wu J, Yang X: O-GlcNAc signaling in cancer metabolism and epigenetics. Cancer Lett. 2015 Jan 28; 2014 Apr 24. PMID: 24769077

Kurup PK, Xu J, Videira RA, Ononenyi C, Baltazar G, Lombroso PJ, Nairn AC: STEP61 is a substrate of the E3 ligase parkin and is upregulated in Parkinson's disease. Proc Natl Acad Sci U S A. 2015 Jan 27; 2015 Jan 12. PMID: 25583483

Vatner DF, Majumdar SK, Kumashiro N, Petersen MC, Rahimi Y, Gattu AK, Bears M, Camporez JP, Cline GW, Jurczak MJ, Samuel VT, Shulman GI: Insulin-independent regulation of hepatic triglyceride synthesis by fatty acids. Proc Natl Acad Sci U S A. 2015 Jan 27; 2015 Jan 6. PMID: 25564660

Jhingran A, Kasahara S, Shepardson KM, Junecko BA, Heung LJ, Kumasaka DK, Knoblaugh SE, Lin X, Kazmierczak BI, Reinhart TA, Cramer RA, Hohl TM: Compartment-specific and sequential role of MyD88 and CARD9 in chemokine induction and innate defense during respiratory fungal infection. PLoS Pathog. 2015 Jan; 2015 Jan 26. PMID: 25621893

Murray PB, Lax I, Reshetnyak A, Ligon GF, Lillquist JS, Natoli EJ Jr, Shi X, Folta-Stogniew E, Gunel M, Alvarado D, Schlessinger J: Heparin is an activating ligand of the orphan receptor tyrosine kinase ALK. Sci Signal. 2015 Jan 20; 2015 Jan 20. PMID: 25605972

Sureshbabu A, Syed MA, Boddupalli CS, Dhodapkar MV, Homer RJ, Minoo P, Bhandari V: Conditional overexpression of TGFβ1 promotes pulmonary inflammation, apoptosis and mortality via TGFβR2 in the developing mouse lung. Respir Res. 2015 Jan 16; 2015 Jan 16. PMID: 25591994

Banks AS, McAllister FE, Camporez JP, Zushin PJ, Jurczak MJ, Laznik-Bogoslavski D, Shulman GI, Gygi SP, Spiegelman BM: An ERK/Cdk5 axis controls the diabetogenic actions of PPARγ. Nature. 2015 Jan 15; 2014 Nov 17. PMID: 25409143

Klein M, Afonso B, Vonner AJ, Hernandez-Nunez L, Berck M, Tabone CJ, Kane EA, Pieribone VA, Nitabach MN, Cardona A, Zlatic M, Sprecher SG, Gershow M, Garrity PA, Samuel AD: Sensory determinants of behavioral dynamics in Drosophila thermotaxis. Proc Natl Acad Sci U S A. 2015 Jan 13; 2014 Dec 30. PMID: 25550513

Damsky W, Micevic G, Meeth K, Muthusamy V, Curley DP, Santhanakrishnan M, Erdelyi I, Platt JT, Huang L, Theodosakis N, Zaidi MR, Tighe S, Davies MA, Dankort D, McMahon M, Merlino G, Bardeesy N, Bosenberg M: mTORC1 activation blocks BrafV600E-induced growth arrest but is insufficient for melanoma formation. Cancer Cell. 2015 Jan 12. PMID: 25584893

Schueler M, Braun DA, Chandrasekar G, Gee HY, Klasson TD, Halbritter J, Bieder A, Porath JD, Airik R, Zhou W, LoTurco JJ, Che A, Otto EA, Böckenhauer D, Sebire NJ, Honzik T, Harris PC, Koon SJ, Gunay-Aygun M, Saunier S, Zerres K, Bruechle NO, Drenth JP, Pelletier L, Tapia-Páez I, Lifton RP, Giles RH, Kere J, Hildebrandt F: DCDC2 mutations cause a renal-hepatic ciliopathy by disrupting Wnt signaling. Am J Hum Genet. 2015 Jan 8; 2014 Dec 31. PMID: 25557784

Marshall HD, Ray JP, Laidlaw BJ, Zhang N, Gawande D, Staron MM, Craft J, Kaech SM: The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa. Elife. 2015 Jan 8; 2015 Jan 8. PMID: 25569154

Bancroft T, Bouaouina M, Roberts S, Lee M, Calderwood DA, Schwartz M, Simons M, Sessa WC, Kyriakides TR: Up-regulation of thrombospondin-2 in Akt1-null mice contributes to compromised tissue repair due to abnormalities in fibroblast function. J Biol Chem. 2015 Jan 2; 2014 Nov 11. PMID: 25389299

Ananthanarayanan M, Banales JM, Guerra MT, Spirli C, Munoz-Garrido P, Mitchell-Richards K, Tafur D, Saez E, Nathanson MH: Post-translational regulation of the type III inositol 1,4,5-trisphosphate receptor by miRNA-506. J Biol Chem. 2015 Jan 2; 2014 Nov 5. PMID: 25378392

Roden C, Mastriano S, Wang N, Lu J: microRNA Expression Profiling: Technologies, Insights, and Prospects. Adv Exp Med Biol. 2015. PMID: 26663195

Moore LB, Kyriakides TR: Molecular Characterization of Macrophage-Biomaterial Interactions. Adv Exp Med Biol. 2015. PMID: 26306446

Qian H, Xu X, Niklason LE: PCH-2 regulates Caenorhabditis elegans lifespan. Aging (Albany NY). 2015 Jan. PMID: 25635513

Thorne JT, Segal TR, Chang S, Jorge S, Segars JH, Leppert PC: Dynamic reciprocity between cells and their microenvironment in reproduction. Biol Reprod. 2015 Jan; 2014 Nov 19. PMID: 25411389

Acquavella N, Clever D, Yu Z, Roelke-Parker M, Palmer DC, Xi L, Pflicke H, Ji Y, Gros A, Hanada K, Goldlust IS, Mehta GU, Klebanoff CA, Crompton JG, Sukumar M, Morrow JJ, Franco Z, Gattinoni L, Liu H, Wang E, Marincola F, Stroncek DF, Lee CC, Raffeld M, Bosenberg MW, Roychoudhuri R, Restifo NP: Type I cytokines synergize with oncogene inhibition to induce tumor growth arrest. Cancer Immunol Res. 2015 Jan; 2014 Oct 30. PMID: 25358764

Conway DE, Schwartz MA: Mechanotransduction of shear stress occurs through changes in VE-cadherin and PECAM-1 tension: implications for cell migration. Cell Adh Migr. 2015; 2014 Oct 3. PMID: 25482618

Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Campanella M, Candi E, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, Di Daniele N, Dixit VM, Dynlacht BD, El-Deiry WS, Fimia GM, Flavell RA, Fulda S, Garrido C, Gougeon ML, Green DR, Gronemeyer H, Hajnoczky G, Hardwick JM, Hengartner MO, Ichijo H, Joseph B, Jost PJ, Kaufmann T, Kepp O, Klionsky DJ, Knight RA, Kumar S, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lugli E, Madeo F, Malorni W, Marine JC, Martin SJ, Martinou JC, Medema JP, Meier P, Melino S, Mizushima N, Moll U, Muñoz-Pinedo C, Nuñez G, Oberst A, Panaretakis T, Penninger JM, Peter ME, Piacentini M, Pinton P, Prehn JH, Puthalakath H, Rabinovich GA, Ravichandran KS, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Shi Y, Simon HU, Stockwell BR, Szabadkai G, Tait SW, Tang HL, Tavernarakis N, Tsujimoto Y, Vanden Berghe T, Vandenabeele P, Villunger A, Wagner EF, Walczak H, White E, Wood WG, Yuan J, Zakeri Z, Zhivotovsky B, Melino G, Kroemer G: Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death Differ. 2015 Jan; 2014 Sep 19. PMID: 25236395

Taylor A, Halene S: The regulatory role of serum response factor pathway in neutrophil inflammatory response. Curr Opin Hematol. 2015 Jan. PMID: 25402621

Taylor JR, Torregrossa MM: Pharmacological disruption of maladaptive memory. Handb Exp Pharmacol. 2015. PMID: 25977090

Dilshara MG, Lee KT, Lee CM, Choi YH, Lee HJ, Choi IW, Kim GY: New compound, 5-O-isoferuloyl-2-deoxy-D-ribono-γ-lacton from Clematis mandshurica: Anti-inflammatory effects in lipopolysaccharide-stimulated BV2 microglial cells. Int Immunopharmacol. 2015 Jan; 2014 Nov 8. PMID: 25445966

Wise A, Tenezaca L, Fernandez RW, Schatoff E, Flores J, Ueda A, Zhong X, Wu CF, Simon AF, Venkatesh T: Drosophila mutants of the autism candidate gene neurobeachin (rugose) exhibit neuro-developmental disorders, aberrant synaptic properties, altered locomotion, and impaired adult social behavior and activity patterns. J Neurogenet. 2015; 2015 Jul 14. PMID: 26100104

Howe JR: Modulation of non-NMDA receptor gating by auxiliary subunits. J Physiol. 2015 Jan 1; 2014 Sep 22. PMID: 25556788

Qian F, Montgomery RR: Imaging Immunosenescence. Methods Mol Biol. 2015. PMID: 26420711

Lee H, Bennett AM: Identification of receptor protein tyrosine phosphatases (RPTPs) as regulators of receptor tyrosine kinases (RTKs) using an RPTP siRNA-RTK substrate screen. Methods Mol Biol. 2015. PMID: 25319894

Lawan A, Zhang L, Gatzke F, Min K, Jurczak MJ, Al-Mutairi M, Richter P, Camporez JP, Couvillon A, Pesta D, Roth Flach RJ, Shulman GI, Bennett AM: Hepatic mitogen-activated protein kinase phosphatase 1 selectively regulates glucose metabolism and energy homeostasis. Mol Cell Biol. 2015 Jan; 2014 Oct 13. PMID: 25312648

Carranza K, Veron D, Cercado A, Bautista N, Pozo W, Tufro A, Veron D: Cellular and molecular aspects of diabetic nephropathy; the role of VEGF-A. Nefrologia. 2015; 2015 Jun 23. PMID: 26300505

Plemenitas A, Kastelic M, o Porcelli S, Serretti A, Dolžan V, Kores Plesnicar B: Alcohol Dependence and Genetic Variability in the Serotonin Pathway among Currently and Formerly Alcohol-Dependent Males. Neuropsychobiology. 2015. PMID: 26352193

Sanacora G, Schatzberg AF: Ketamine: promising path or false prophecy in the development of novel therapeutics for mood disorders? Neuropsychopharmacology. 2015 Jan; 2014 Sep 26. PMID: 25257213

Webster BM, Lusk CP: ESCRTs breach the nuclear border. Nucleus. 2015; 2015 May 5. PMID: 25942571

Lee H, Yi JS, Lawan A, Min K, Bennett AM: Mining the function of protein tyrosine phosphatases in health and disease. Semin Cell Dev Biol. 2015 Jan; 2014 Sep 26. PMID: 25263013

Ni W, Odunuga OO: UCS proteins: chaperones for myosin and co-chaperones for Hsp90. Subcell Biochem. 2015. PMID: 25487020

Schimmack S, Taylor A, Lawrence B, Schmitz-Winnenthal H, Fischer L, Büchler MW, Modlin IM, Kidd M, Tang LH: Stathmin in pancreatic neuroendocrine neoplasms: a marker of proliferation and PI3K signaling. Tumour Biol. 2015 Jan; 2014 Sep 30. PMID: 25266798

Patterson VL, Zullo AJ, Koenig C, Stoessel S, Jo H, Liu X, Han J, Choi M, DeWan AT, Thomas JL, Kuan CY, Hoh J: Neural-specific deletion of Htra2 causes cerebellar neurodegeneration and defective processing of mitochondrial OPA1. PLoS One. 2014; 2014 Dec 22. PMID: 25531304

Rongvaux A, Jackson R, Harman CC, Li T, West AP, de Zoete MR, Wu Y, Yordy B, Lakhani SA, Kuan CY, Taniguchi T, Shadel GS, Chen ZJ, Iwasaki A, Flavell RA: Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA. Cell. 2014 Dec 18. PMID: 25525875

Cagavi E, Bartulos O, Suh CY, Sun B, Yue Z, Jiang Z, Yue L, Qyang Y: Functional cardiomyocytes derived from Isl1 cardiac progenitors via Bmp4 stimulation. PLoS One. 2014; 2014 Dec 18. PMID: 25522363

Liang X, Madrid J, Howard J: The microtubule-based cytoskeleton is a component of a mechanical signaling pathway in fly campaniform receptors. Biophys J. 2014 Dec 16. PMID: 25517144

Gao Y, Wu F, Zhou J, Yan L, Jurczak MJ, Lee HY, Yang L, Mueller M, Zhou XB, Dandolo L, Szendroedi J, Roden M, Flannery C, Taylor H, Carmichael GG, Shulman GI, Huang Y: The H19/let-7 double-negative feedback loop contributes to glucose metabolism in muscle cells. Nucleic Acids Res. 2014 Dec 16; 2014 Nov 15. PMID: 25399420

Carvalho L, Jacinto A, Matova N: The Toll/NF-κB signaling pathway is required for epidermal wound repair in Drosophila. Proc Natl Acad Sci U S A. 2014 Dec 16; 2014 Nov 26. PMID: 25427801

Beck TC, Gomes AC, Cyster JG, Pereira JP: CXCR4 and a cell-extrinsic mechanism control immature B lymphocyte egress from bone marrow. J Exp Med. 2014 Dec 15; 2014 Nov 17. PMID: 25403444

Cui H, Wang Y, Huang H, Yu W, Bai M, Zhang L, Bryan BA, Wang Y, Luo J, Li D, Ma Y, Liu M: GPR126 protein regulates developmental and pathological angiogenesis through modulation of VEGFR2 receptor signaling. J Biol Chem. 2014 Dec 12; 2014 Sep 12. PMID: 25217645

Haskins JW, Nguyen DX, Stern DF: Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration. Sci Signal. 2014 Dec 9; 2014 Dec 9. PMID: 25492965

Yaffe D, Vergara-Jaque A, Shuster Y, Listov D, Meena S, Singh SK, Forrest LR, Schuldiner S: Functionally important carboxyls in a bacterial homologue of the vesicular monoamine transporter (VMAT). J Biol Chem. 2014 Dec 5; 2014 Oct 21. PMID: 25336661

Simonds SE, Pryor JT, Ravussin E, Greenway FL, Dileone R, Allen AM, Bassi J, Elmquist JK, Keogh JM, Henning E, Myers MG Jr, Licinio J, Brown RD, Enriori PJ, O'Rahilly S, Sternson SM, Grove KL, Spanswick DC, Farooqi IS, Cowley MA: Leptin mediates the increase in blood pressure associated with obesity. Cell. 2014 Dec 4. PMID: 25480301

Taylor RA, Hammond MD, Ai Y, Sansing LH: CX3CR1 signaling on monocytes is dispensable after intracerebral hemorrhage. PLoS One. 2014; 2014 Dec 3. PMID: 25469644

Rhee A, Cheong R, Levchenko A: Noise decomposition of intracellular biochemical signaling networks using nonequivalent reporters. Proc Natl Acad Sci U S A. 2014 Dec 2; 2014 Nov 17. PMID: 25404303

Baeyens N, Mulligan-Kehoe MJ, Corti F, Simon DD, Ross TD, Rhodes JM, Wang TZ, Mejean CO, Simons M, Humphrey J, Schwartz MA: Syndecan 4 is required for endothelial alignment in flow and atheroprotective signaling. Proc Natl Acad Sci U S A. 2014 Dec 2; 2014 Nov 17. PMID: 25404299

Feriod CN, Nguyen L, Jurczak MJ, Kruglov EA, Nathanson MH, Shulman GI, Bennett AM, Ehrlich BE: Inositol 1,4,5-trisphosphate receptor type II (InsP3R-II) is reduced in obese mice, but metabolic homeostasis is preserved in mice lacking InsP3R-II. Am J Physiol Endocrinol Metab. 2014 Dec 1; 2014 Oct 14. PMID: 25315698

Chabu C, Xu T: Oncogenic Ras stimulates Eiger/TNF exocytosis to promote growth. Development. 2014 Dec; 2014 Nov 19. PMID: 25411211

Samuel VT: The emerging role of oestrogen-related receptor γ as a regulator of energy metabolism. Diabetologia. 2014 Dec; 2014 Sep 26. PMID: 25257097

Rapanelli M, Frick LR, Pogorelov V, Ota KT, Abbasi E, Ohtsu H, Pittenger C: Dysregulated intracellular signaling in the striatum in a pathophysiologically grounded model of Tourette syndrome. Eur Neuropsychopharmacol. 2014 Dec; 2014 Nov 4. PMID: 25464894

Persson AK, Estacion M, Ahn H, Liu S, Stamboulian-Platel S, Waxman SG, Black JA: Contribution of sodium channels to lamellipodial protrusion and Rac1 and ERK1/2 activation in ATP-stimulated microglia. Glia. 2014 Dec; 2014 Jul 18. PMID: 25043721

MacLean DM, Ramaswamy SS, Du M, Howe JR, Jayaraman V: Stargazin promotes closure of the AMPA receptor ligand-binding domain. J Gen Physiol. 2014 Dec. PMID: 25422502

Obinata H, Gutkind S, Stitham J, Okuno T, Yokomizo T, Hwa J, Hla T: Individual variation of human S1P₁ coding sequence leads to heterogeneity in receptor function and drug interactions. J Lipid Res. 2014 Dec; 2014 Oct 7. PMID: 25293589

Moskwa P, Zinn PO, Choi YE, Shukla SA, Fendler W, Chen CC, Lu J, Golub TR, Hjelmeland A, Chowdhury D: A functional screen identifies miRs that induce radioresistance in glioblastomas. Mol Cancer Res. 2014 Dec; 2014 Sep 25. PMID: 25256711

Tsuneki M, Madri JA: Adhesion molecule-mediated hippo pathway modulates hemangioendothelioma cell behavior. Mol Cell Biol. 2014 Dec; 2014 Sep 29. PMID: 25266662

Ju H, Kokubu H, Lim J: Beyond the glutamine expansion: influence of posttranslational modifications of ataxin-1 in the pathogenesis of spinocerebellar ataxia type 1. Mol Neurobiol. 2014 Dec; 2014 Apr 22. PMID: 24752589

Xie T, Lim SM, Westover KD, Dodge ME, Ercan D, Ficarro SB, Udayakumar D, Gurbani D, Tae HS, Riddle SM, Sim T, Marto JA, Jänne PA, Crews CM, Gray NS: Pharmacological targeting of the pseudokinase Her3. Nat Chem Biol. 2014 Dec; 2014 Oct 19. PMID: 25326665

Humphrey JD, Dufresne ER, Schwartz MA: Mechanotransduction and extracellular matrix homeostasis. Nat Rev Mol Cell Biol. 2014 Dec; 2014 Oct 22. PMID: 25355505

Zhang H, Zhao X, Li J, Cai H, Deng XW, Li L: MicroRNA408 is critical for the HY5-SPL7 gene network that mediates the coordinated response to light and copper. Plant Cell. 2014 Dec; 2014 Dec 16. PMID: 25516599

Amaya MJ, Oliveira AG, Schroeder LK, Allgeyer ES, Bewersdorf J, Nathanson MH: Apical localization of inositol 1,4,5-trisphosphate receptors is independent of extended synaptotagmins in hepatocytes. PLoS One. 2014; 2014 Dec 1. PMID: 25437447

Song K, Wang S, Mani M, Mani A: Wnt signaling, de novo lipogenesis, adipogenesis and ectopic fat. Oncotarget. 2014 Nov 30. PMID: 25526027

Karlin KL, Mondal G, Hartman JK, Tyagi S, Kurley SJ, Bland CS, Hsu TY, Renwick A, Fang JE, Migliaccio I, Callaway C, Nair A, Dominguez-Vidana R, Nguyen DX, Osborne CK, Schiff R, Yu-Lee LY, Jung SY, Edwards DP, Hilsenbeck SG, Rosen JM, Zhang XH, Shaw CA, Couch FJ, Westbrook TF: The oncogenic STP axis promotes triple-negative breast cancer via degradation of the REST tumor suppressor. Cell Rep. 2014 Nov 20; 2014 Nov 6. PMID: 25453754

Yan C, Liu D, Li L, Wempe MF, Guin S, Khanna M, Meier J, Hoffman B, Owens C, Wysoczynski CL, Nitz MD, Knabe WE, Ahmed M, Brautigan DL, Paschal BM, Schwartz MA, Jones DN, Ross D, Meroueh SO, Theodorescu D: Discovery and characterization of small molecules that target the GTPase Ral. Nature. 2014 Nov 20; 2014 Sep 14. PMID: 25219851

Steiner J, Martins-de-Souza D, Schiltz K, Sarnyai Z, Westphal S, Isermann B, Dobrowolny H, Turck CW, Bogerts B, Bernstein HG, Horvath TL, Schild L, Keilhoff G: Clozapine promotes glycolysis and myelin lipid synthesis in cultured oligodendrocytes. Front Cell Neurosci. 2014; 2014 Nov 18. PMID: 25477781

Rosenstein RK, Bezbradica JS, Yu S, Medzhitov R: Signaling pathways activated by a protease allergen in basophils. Proc Natl Acad Sci U S A. 2014 Nov 18; 2014 Nov 4. PMID: 25369937

Kuo IY, Kwaczala AT, Nguyen L, Russell KS, Campbell SG, Ehrlich BE: Decreased polycystin 2 expression alters calcium-contraction coupling and changes β-adrenergic signaling pathways. Proc Natl Acad Sci U S A. 2014 Nov 18; 2014 Nov 3. PMID: 25368166

Kravtsov D, Mashukova A, Forteza R, Rodriguez MM, Ameen NA, Salas PJ: Myosin 5b loss of function leads to defects in polarized signaling: implication for microvillus inclusion disease pathogenesis and treatment. Am J Physiol Gastrointest Liver Physiol. 2014 Nov 15; 2014 Sep 25. PMID: 25258405

Gulden FO, Šestan N: Neurobiology: building a bigger brain. Nature. 2014 Nov 13. PMID: 25391958

Lee A, Fakler B, Kaczmarek LK, Isom LL: More than a pore: ion channel signaling complexes. J Neurosci. 2014 Nov 12. PMID: 25392484

Gao F, Chambon P, Tellides G, Kong W, Zhang X, Li W: Disruption of TGF-β signaling in smooth muscle cell prevents flow-induced vascular remodeling. Biochem Biophys Res Commun. 2014 Nov 7; 2014 Oct 24. PMID: 25451249

Gao F, Chambon P, Offermanns S, Tellides G, Kong W, Zhang X, Li W: Disruption of TGF-β signaling in smooth muscle cell prevents elastase-induced abdominal aortic aneurysm. Biochem Biophys Res Commun. 2014 Nov 7; 2014 Oct 18. PMID: 25450370

Howard J: Quantitative cell biology: the essential role of theory. Mol Biol Cell. 2014 Nov 5. PMID: 25368416

Chiba K, Araseki M, Nozawa K, Furukori K, Araki Y, Matsushima T, Nakaya T, Hata S, Saito Y, Uchida S, Okada Y, Nairn AC, Davis RJ, Yamamoto T, Kinjo M, Taru H, Suzuki T: Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport. Mol Biol Cell. 2014 Nov 5; 2014 Aug 27. PMID: 25165140

Yutzey KE, Demer LL, Body SC, Huggins GS, Towler DA, Giachelli CM, Hofmann-Bowman MA, Mortlock DP, Rogers MB, Sadeghi MM, Aikawa E: Calcific aortic valve disease: a consensus summary from the Alliance of Investigators on Calcific Aortic Valve Disease. Arterioscler Thromb Vasc Biol. 2014 Nov; 2014 Sep 4. PMID: 25189570

Kris MG, Arenberg DA, Herbst RS, Riely GJ: Emerging science and therapies in non-small-cell lung cancer: targeting the MET pathway. Clin Lung Cancer. 2014 Nov. PMID: 25306384

Dragoi AM, Agaisse H: The serine/threonine kinase STK11 promotes Shigella flexneri dissemination through establishment of cell-cell contacts competent for tyrosine kinase signaling. Infect Immun. 2014 Nov; 2014 Aug 11. PMID: 25114112

Yu P, Tung JK, Simons M: Lymphatic fate specification: an ERK-controlled transcriptional program. Microvasc Res. 2014 Nov; 2014 Aug 15. PMID: 25132472

Kim SH, Lee JH, Seo KI, Ryu B, Sung Y, Chung T, Deng XW, Lee JH: Characterization of a Novel DWD protein that participates in heat stress response in Arabidopsis. Mol Cells. 2014 Nov; 2014 Oct 2. PMID: 25358503

Raina K, Noblin DJ, Serebrenik YV, Adams A, Zhao C, Crews CM: Targeted protein destabilization reveals an estrogen-mediated ER stress response. Nat Chem Biol. 2014 Nov; 2014 Sep 21. PMID: 25242550

Sistigu A, Yamazaki T, Vacchelli E, Chaba K, Enot DP, Adam J, Vitale I, Goubar A, Baracco EE, Remédios C, Fend L, Hannani D, Aymeric L, Ma Y, Niso-Santano M, Kepp O, Schultze JL, Tüting T, Belardelli F, Bracci L, La Sorsa V, Ziccheddu G, Sestili P, Urbani F, Delorenzi M, Lacroix-Triki M, Quidville V, Conforti R, Spano JP, Pusztai L, Poirier-Colame V, Delaloge S, Penault-Llorca F, Ladoire S, Arnould L, Cyrta J, Dessoliers MC, Eggermont A, Bianchi ME, Pittet M, Engblom C, Pfirschke C, Préville X, Uzè G, Schreiber RD, Chow MT, Smyth MJ, Proietti E, André F, Kroemer G, Zitvogel L: Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy. Nat Med. 2014 Nov; 2014 Oct 26. PMID: 25344738

Sreekumar BK, Belinsky GS, Einwachter H, Rhim AD, Schmid R, Chung C: Polarization of the vacuolar adenosine triphosphatase delineates a transition to high-grade pancreatic intraepithelial neoplasm lesions. Pancreas. 2014 Nov. PMID: 25072283

Samji T, Hong S, Means RE: The Membrane Associated RING-CH Proteins: A Family of E3 Ligases with Diverse Roles through the Cell. Int Sch Res Notices. 2014; 2014 Oct 29. PMID: 27419207

Schwab CL, Bellone S, English DP, Roque DM, Lopez S, Cocco E, Nicoletti R, Bortolomai I, Bonazzoli E, Ratner E, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Santin AD: Afatinib demonstrates remarkable activity against HER2-amplified uterine serous endometrial cancer in vitro and in vivo. Br J Cancer. 2014 Oct 28; 2014 Sep 30. PMID: 25268372

Shibata S, Arroyo JP, Castañeda-Bueno M, Puthumana J, Zhang J, Uchida S, Stone KL, Lam TT, Lifton RP: Angiotensin II signaling via protein kinase C phosphorylates Kelch-like 3, preventing WNK4 degradation. Proc Natl Acad Sci U S A. 2014 Oct 28; 2014 Oct 13. PMID: 25313067

Kasper DM, Wang G, Gardner KE, Johnstone TG, Reinke V: The C. elegans SNAPc component SNPC-4 coats piRNA domains and is globally required for piRNA abundance. Dev Cell. 2014 Oct 27. PMID: 25373775

So JH, Kim JD, Yoo KW, Kim HT, Jung SH, Choi JH, Lee MS, Jin SW, Kim CH: FIH-1, a novel interactor of mindbomb, functions as an essential anti-angiogenic factor during zebrafish vascular development. PLoS One. 2014; 2014 Oct 27. PMID: 25347788

Xu HP, Sun JH, Tian N: A general principle governs vision-dependent dendritic patterning of retinal ganglion cells. J Comp Neurol. 2014 Oct 15; 2014 Apr 29. PMID: 24737624

Chen M, Lee S, Park SJ, Looger LL, Zhou ZJ: Receptive field properties of bipolar cell axon terminals in direction-selective sublaminas of the mouse retina. J Neurophysiol. 2014 Oct 15; 2014 Jul 16. PMID: 25031256

Cazet A, Charest J, Bennett DC, Sambrooks CL, Contessa JN: Mannose phosphate isomerase regulates fibroblast growth factor receptor family signaling and glioma radiosensitivity. PLoS One. 2014; 2014 Oct 14. PMID: 25314669

Schneider ER, Mastrotto M, Laursen WJ, Schulz VP, Goodman JB, Funk OH, Gallagher PG, Gracheva EO, Bagriantsev SN: Neuronal mechanism for acute mechanosensitivity in tactile-foraging waterfowl. Proc Natl Acad Sci U S A. 2014 Oct 14; 2014 Sep 22. PMID: 25246547

Haas LT, Kostylev MA, Strittmatter SM: Therapeutic molecules and endogenous ligands regulate the interaction between brain cellular prion protein (PrPC) and metabotropic glutamate receptor 5 (mGluR5). J Biol Chem. 2014 Oct 10; 2014 Aug 22. PMID: 25148681

Olds WH, Xu T: Regulation of food intake by mechanosensory ion channels in enteric neurons. Elife. 2014 Oct 6; 2014 Oct 6. PMID: 25285450

Farooq A, Hoque R, Ouyang X, Farooq A, Ghani A, Ahsan K, Guerra M, Mehal WZ: Activation of N-methyl-d-aspartate receptor downregulates inflammasome activity and liver inflammation via a β-arrestin-2 pathway. Am J Physiol Gastrointest Liver Physiol. 2014 Oct 1; 2014 Aug 7. PMID: 25104498

Lin L, Chamberlain L, Pak ML, Nagarajan A, Gupta R, Zhu LJ, Wright CM, Fong KM, Wajapeyee N, Green MR: A large-scale RNAi-based mouse tumorigenesis screen identifies new lung cancer tumor suppressors that repress FGFR signaling. Cancer Discov. 2014 Oct; 2014 Jul 11. PMID: 25015643

Nandhu MS, Hu B, Cole SE, Erdreich-Epstein A, Rodriguez-Gil DJ, Viapiano MS: Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas. Cancer Res. 2014 Oct 1; 2014 Aug 19. PMID: 25139440

Huang X, Ouyang X, Deng XW: Beyond repression of photomorphogenesis: role switching of COP/DET/FUS in light signaling. Curr Opin Plant Biol. 2014 Oct; 2014 Jul 25. PMID: 25061897

Zhao JW, Dyson SC, Kriegel C, Tyers P, He X, Fahmy TM, Metcalfe SM, Barker RA: Modelling of a targeted nanotherapeutic 'stroma' to deliver the cytokine LIF, or XAV939, a potent inhibitor of Wnt-β-catenin signalling, for use in human fetal dopaminergic grafts in Parkinson's disease. Dis Model Mech. 2014 Oct; 2014 Aug 1. PMID: 25085990

Lahiri A, Abraham C: Activation of pattern recognition receptors up-regulates metallothioneins, thereby increasing intracellular accumulation of zinc, autophagy, and bacterial clearance by macrophages. Gastroenterology. 2014 Oct; 2014 Jun 21. PMID: 24960189

Schwab CL, English DP, Roque DM, Bellone S, Lopez S, Cocco E, Nicoletti R, Rutherford TJ, Schwartz PE, Santin AD: Neratinib shows efficacy in the treatment of HER2/neu amplified uterine serous carcinoma in vitro and in vivo. Gynecol Oncol. 2014 Oct; 2014 Aug 12. PMID: 25124161

Huet-Calderwood C, Brahme NN, Kumar N, Stiegler AL, Raghavan S, Boggon TJ, Calderwood DA: Differences in binding to the ILK complex determines kindlin isoform adhesion localization and integrin activation. J Cell Sci. 2014 Oct 1; 2014 Aug 1. PMID: 25086068

Iwakiri Y, Shah V, Rockey DC: Vascular pathobiology in chronic liver disease and cirrhosis - current status and future directions. J Hepatol. 2014 Oct; 2014 Jun 6. PMID: 24911462

Zhang L, Bartley CM, Gong X, Hsieh LS, Lin TV, Feliciano DM, Bordey A: MEK-ERK1/2-dependent FLNA overexpression promotes abnormal dendritic patterning in tuberous sclerosis independent of mTOR. Neuron. 2014 Oct 1. PMID: 25277454

Simpson CA, Foer D, Lee GS, Bihuniak J, Sun B, Sullivan R, Belsky J, Insogna KL: Serum levels of sclerostin, Dickkopf-1, and secreted frizzled-related protein-4 are not changed in individuals with high bone mass causing mutations in LRP5. Osteoporos Int. 2014 Oct; 2014 Jun 14. PMID: 24927689

Eckerdt F, Beauchamp E, Bell J, Iqbal A, Su B, Fukunaga R, Lulla RR, Goldman S, Platanias LC: Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells. Oncotarget. 2014 Sep 30. PMID: 25193863

Kuo IY, DesRochers TM, Kimmerling EP, Nguyen L, Ehrlich BE, Kaplan DL: Cyst formation following disruption of intracellular calcium signaling. Proc Natl Acad Sci U S A. 2014 Sep 30; 2014 Sep 16. PMID: 25228769

Lew ED, Oh J, Burrola PG, Lax I, Zagórska A, Través PG, Schlessinger J, Lemke G: Differential TAM receptor-ligand-phospholipid interactions delimit differential TAM bioactivities. Elife. 2014 Sep 29; 2014 Sep 29. PMID: 25265470

Ricard N, Simons M: Fox(y) regulators of VEGF receptors. Circ Res. 2014 Sep 26. PMID: 25258399

Chen PY, Qin L, Tellides G, Simons M: Fibroblast growth factor receptor 1 is a key inhibitor of TGFβ signaling in the endothelium. Sci Signal. 2014 Sep 23; 2014 Sep 23. PMID: 25249657

Morrison AR, Yarovinsky TO, Young BD, Moraes F, Ross TD, Ceneri N, Zhang J, Zhuang ZW, Sinusas AJ, Pardi R, Schwartz MA, Simons M, Bender JR: Chemokine-coupled β2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis. J Exp Med. 2014 Sep 22; 2014 Sep 1. PMID: 25180062

Elitas M, Brower K, Lu Y, Chen JJ, Fan R: A microchip platform for interrogating tumor-macrophage paracrine signaling at the single-cell level. Lab Chip. 2014 Sep 21; 2014 Jul 24. PMID: 25057779

Lv C, Zenisek D: Big minis from hair cells: mechanism and function. Neuron. 2014 Sep 17. PMID: 25233300

Hedl M, Abraham C: A TNFSF15 disease-risk polymorphism increases pattern-recognition receptor-induced signaling through caspase-8-induced IL-1. Proc Natl Acad Sci U S A. 2014 Sep 16; 2014 Sep 2. PMID: 25197060

El-Hassar L, Simen AA, Duque A, Patel KD, Kaczmarek LK, Arnsten AF, Yeckel MF: Disrupted in schizophrenia 1 modulates medial prefrontal cortex pyramidal neuron activity through cAMP regulation of transient receptor potential C and small-conductance K+ channels. Biol Psychiatry. 2014 Sep 15; 2014 Jan 20. PMID: 24560582

Lanahan AA, Lech D, Dubrac A, Zhang J, Zhuang ZW, Eichmann A, Simons M: PTP1b is a physiologic regulator of vascular endothelial growth factor signaling in endothelial cells. Circulation. 2014 Sep 9; 2014 Jun 30. PMID: 24982127

Li MW, Wang J, Zhao YO, Fikrig E: Innexin AGAP001476 is critical for mediating anti-Plasmodium responses in Anopheles mosquitoes. J Biol Chem. 2014 Sep 5; 2014 Jul 17. PMID: 25035430

Lee MY, Luciano AK, Ackah E, Rodriguez-Vita J, Bancroft TA, Eichmann A, Simons M, Kyriakides TR, Morales-Ruiz M, Sessa WC: Endothelial Akt1 mediates angiogenesis by phosphorylating multiple angiogenic substrates. Proc Natl Acad Sci U S A. 2014 Sep 2; 2014 Aug 18. PMID: 25136137

Kim JD, Lee HW, Jin SW: Diversity is in my veins: role of bone morphogenetic protein signaling during venous morphogenesis in zebrafish illustrates the heterogeneity within endothelial cells. Arterioscler Thromb Vasc Biol. 2014 Sep; 2014 Jul 24. PMID: 25060789

Zhang X, Simons M: Receptor tyrosine kinases endocytosis in endothelium: biology and signaling. Arterioscler Thromb Vasc Biol. 2014 Sep; 2014 Jun 12. PMID: 24925972

Guo X, Wang L, Velazquez H, Safirstein R, Desir GV: Renalase: its role as a cytokine, and an update on its association with type 1 diabetes and ischemic stroke. Curr Opin Nephrol Hypertens. 2014 Sep. PMID: 24992568

Lin AL, Coman D, Jiang L, Rothman DL, Hyder F: Caloric restriction impedes age-related decline of mitochondrial function and neuronal activity. J Cereb Blood Flow Metab. 2014 Sep; 2014 Jul 2. PMID: 24984898

Higley MJ: Localized GABAergic inhibition of dendritic Ca(2+) signalling. Nat Rev Neurosci. 2014 Sep; 2014 Aug 13. PMID: 25116141

Jorge S, Chang S, Barzilai JJ, Leppert P, Segars JH: Mechanical signaling in reproductive tissues: mechanisms and importance. Reprod Sci. 2014 Sep; 2014 Jul 6. PMID: 25001021

Shulman Z, Gitlin AD, Weinstein JS, Lainez B, Esplugues E, Flavell RA, Craft JE, Nussenzweig MC: Dynamic signaling by T follicular helper cells during germinal center B cell selection. Science. 2014 Aug 29. PMID: 25170154

Kang H, Kerloc'h A, Rotival M, Xu X, Zhang Q, D'Souza Z, Kim M, Scholz JC, Ko JH, Srivastava PK, Genzen JR, Cui W, Aitman TJ, Game L, Melvin JE, Hanidu A, Dimock J, Zheng J, Souza D, Behera AK, Nabozny G, Cook HT, Bassett JH, Williams GR, Li J, Vignery A, Petretto E, Behmoaras J: Kcnn4 is a regulator of macrophage multinucleation in bone homeostasis and inflammatory disease. Cell Rep. 2014 Aug 21; 2014 Aug 14. PMID: 25131209

Scortegagna M, Ruller C, Feng Y, Lazova R, Kluger H, Li JL, De SK, Rickert R, Pellecchia M, Bosenberg M, Ronai ZA: Genetic inactivation or pharmacological inhibition of Pdk1 delays development and inhibits metastasis of Braf(V600E)::Pten(-/-) melanoma. Oncogene. 2014 Aug 21; 2013 Sep 16. PMID: 24037523

Gate D, Danielpour M, Rodriguez J Jr, Kim GB, Levy R, Bannykh S, Breunig JJ, Kaech SM, Flavell RA, Town T: T-cell TGF-β signaling abrogation restricts medulloblastoma progression. Proc Natl Acad Sci U S A. 2014 Aug 19; 2014 Jul 31. PMID: 25082897

Yang-Hartwich Y, Gurrea-Soteras M, Sumi N, Joo WD, Holmberg JC, Craveiro V, Alvero AB, Mor G: Ovulation and extra-ovarian origin of ovarian cancer. Sci Rep. 2014 Aug 19; 2014 Aug 19. PMID: 25135607

Messa M, Fernández-Busnadiego R, Sun EW, Chen H, Czapla H, Wrasman K, Wu Y, Ko G, Ross T, Wendland B, De Camilli P: Epsin deficiency impairs endocytosis by stalling the actin-dependent invagination of endocytic clathrin-coated pits. Elife. 2014 Aug 13; 2014 Aug 13. PMID: 25122462

Chen F, Li B, Demone J, Charron JB, Shi X, Deng XW: Photoreceptor partner FHY1 has an independent role in gene modulation and plant development under far-red light. Proc Natl Acad Sci U S A. 2014 Aug 12; 2014 Jul 28. PMID: 25071219

Kusne Y, Carrera-Silva EA, Perry AS, Rushing EJ, Mandell EK, Dietrich JD, Errasti AE, Gibbs D, Berens ME, Loftus JC, Hulme C, Yang W, Lu Z, Aldape K, Sanai N, Rothlin CV, Ghosh S: Targeting aPKC disables oncogenic signaling by both the EGFR and the proinflammatory cytokine TNFα in glioblastoma. Sci Signal. 2014 Aug 12; 2014 Aug 12. PMID: 25118327

Nández R, Balkin DM, Messa M, Liang L, Paradise S, Czapla H, Hein MY, Duncan JS, Mann M, De Camilli P: A role of OCRL in clathrin-coated pit dynamics and uncoating revealed by studies of Lowe syndrome cells. Elife. 2014 Aug 8; 2014 Aug 8. PMID: 25107275

Hogan BL, Barkauskas CE, Chapman HA, Epstein JA, Jain R, Hsia CC, Niklason L, Calle E, Le A, Randell SH, Rock J, Snitow M, Krummel M, Stripp BR, Vu T, White ES, Whitsett JA, Morrisey EE: Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function. Cell Stem Cell. 2014 Aug 7. PMID: 25105578

Goodwin JM, Svensson RU, Lou HJ, Winslow MM, Turk BE, Shaw RJ: An AMPK-independent signaling pathway downstream of the LKB1 tumor suppressor controls Snail1 and metastatic potential. Mol Cell. 2014 Aug 7; 2014 Jul 17. PMID: 25042806

Roccabianca S, Bellini C, Humphrey JD: Computational modelling suggests good, bad and ugly roles of glycosaminoglycans in arterial wall mechanics and mechanobiology. J R Soc Interface. 2014 Aug 6. PMID: 24920112

Ouyang X, Huang X, Jin X, Chen Z, Yang P, Ge H, Li S, Deng XW: Coordinated photomorphogenic UV-B signaling network captured by mathematical modeling. Proc Natl Acad Sci U S A. 2014 Aug 5; 2014 Jul 21. PMID: 25049395

Alfadda TI, Saleh AM, Houillier P, Geibel JP: Calcium-sensing receptor 20 years later. Am J Physiol Cell Physiol. 2014 Aug 1; 2014 May 28. PMID: 24871857

Tangney JR, Campbell SG, McCulloch AD, Omens JH: Timing and magnitude of systolic stretch affect myofilament activation and mechanical work. Am J Physiol Heart Circ Physiol. 2014 Aug 1; 2014 May 30. PMID: 24878774

Pober JS, Jane-wit D, Qin L, Tellides G: Interacting mechanisms in the pathogenesis of cardiac allograft vasculopathy. Arterioscler Thromb Vasc Biol. 2014 Aug; 2014 Jun 5. PMID: 24903097

Jo H, Loison F, Luo HR: Microtubule dynamics regulates Akt signaling via dynactin p150. Cell Signal. 2014 Aug; 2014 Apr 12. PMID: 24726838

Vasan N, Boyer JL, Herbst RS: A RAS renaissance: emerging targeted therapies for KRAS-mutated non-small cell lung cancer. Clin Cancer Res. 2014 Aug 1; 2014 Jun 3. PMID: 24893629

Fitzgerald ME, Rawling DC, Vela A, Pyle AM: An evolving arsenal: viral RNA detection by RIG-I-like receptors. Curr Opin Microbiol. 2014 Aug; 2014 Jun 7. PMID: 24912143

Schwab ME, Strittmatter SM: Nogo limits neural plasticity and recovery from injury. Curr Opin Neurobiol. 2014 Aug; 2014 Mar 12. PMID: 24632308

Rothlin CV, Leighton JA, Ghosh S: Tyro3, Axl, and Mertk receptor signaling in inflammatory bowel disease and colitis-associated cancer. Inflamm Bowel Dis. 2014 Aug. PMID: 24846720

Wali VB, Haskins JW, Gilmore-Hebert M, Platt JT, Liu Z, Stern DF: Convergent and divergent cellular responses by ErbB4 isoforms in mammary epithelial cells. Mol Cancer Res. 2014 Aug; 2014 May 14. PMID: 24829397

Paardekooper Overman J, Yi JS, Bonetti M, Soulsby M, Preisinger C, Stokes MP, Hui L, Silva JC, Overvoorde J, Giansanti P, Heck AJ, Kontaridis MI, den Hertog J, Bennett AM: PZR coordinates Shp2 Noonan and LEOPARD syndrome signaling in zebrafish and mice. Mol Cell Biol. 2014 Aug; 2014 May 27. PMID: 24865967

Lozovaya N, Gataullina S, Tsintsadze T, Tsintsadze V, Pallesi-Pocachard E, Minlebaev M, Goriounova NA, Buhler E, Watrin F, Shityakov S, Becker AJ, Bordey A, Milh M, Scavarda D, Bulteau C, Dorfmuller G, Delalande O, Represa A, Cardoso C, Dulac O, Ben-Ari Y, Burnashev N: Selective suppression of excessive GluN2C expression rescues early epilepsy in a tuberous sclerosis murine model. Nat Commun. 2014 Aug 1; 2014 Aug 1. PMID: 25081057

Peng L, Zhang X, Cui X, Zhu D, Wu J, Sun D, Yue Q, Li Z, Liu H, Li G, Zhang J, Xu H, Liu F, Qin C, Li M, Sun J: Paliperidone protects SK-N-SH cells against glutamate toxicity via Akt1/GSK3β signaling pathway. Schizophr Res. 2014 Aug; 2014 Jun 22. PMID: 24962437

Ji W, Yang M, Praggastis A, Li Y, Zhou HJ, He Y, Ghazvinian R, Cincotta DJ, Rice KP, Min W: Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death. PLoS One. 2014; 2014 Jul 28. PMID: 25068797

Reikine S, Nguyen JB, Modis Y: Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5. Front Immunol. 2014; 2014 Jul 23. PMID: 25101084

Guo Y, Sekharan S, Liu J, Batista VS, Tully JC, Yan EC: Unusual kinetics of thermal decay of dim-light photoreceptors in vertebrate vision. Proc Natl Acad Sci U S A. 2014 Jul 22; 2014 Jul 7. PMID: 25002518

Alavian KN, Beutner G, Lazrove E, Sacchetti S, Park HA, Licznerski P, Li H, Nabili P, Hockensmith K, Graham M, Porter GA Jr, Jonas EA: An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore. Proc Natl Acad Sci U S A. 2014 Jul 22; 2014 Jun 16. PMID: 24979777

Demos-Davies KM, Ferguson BS, Cavasin MA, Mahaffey JH, Williams SM, Spiltoir JI, Schuetze KB, Horn TR, Chen B, Ferrara C, Scellini B, Piroddi N, Tesi C, Poggesi C, Jeong MY, McKinsey TA: HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling. Am J Physiol Heart Circ Physiol. 2014 Jul 15; 2014 May 23. PMID: 24858848

Kalinowski A, Ueki I, Min-Oo G, Ballon-Landa E, Knoff D, Galen B, Lanier LL, Nadel JA, Koff JL: EGFR activation suppresses respiratory virus-induced IRF1-dependent CXCL10 production. Am J Physiol Lung Cell Mol Physiol. 2014 Jul 15; 2014 May 16. PMID: 24838750

Weiss BL, Savage AF, Griffith BC, Wu Y, Aksoy S: The peritrophic matrix mediates differential infection outcomes in the tsetse fly gut following challenge with commensal, pathogenic, and parasitic microbes. J Immunol. 2014 Jul 15; 2014 Jun 9. PMID: 24913976

Sun P, Watanabe K, Fallahi M, Lee B, Afetian ME, Rheaume C, Wu D, Horsley V, Dai X: Pygo2 regulates β-catenin-induced activation of hair follicle stem/progenitor cells and skin hyperplasia. Proc Natl Acad Sci U S A. 2014 Jul 15; 2014 Jun 30. PMID: 24982158

Hirschi KK, Li S, Roy K: Induced pluripotent stem cells for regenerative medicine. Annu Rev Biomed Eng. 2014 Jul 11; 2014 May 29. PMID: 24905879

Czochor JR, Glazer PM: microRNAs in cancer cell response to ionizing radiation. Antioxid Redox Signal. 2014 Jul 10; 2014 Feb 4. PMID: 24206455

Vargas KJ, Makani S, Davis T, Westphal CH, Castillo PE, Chandra SS: Synucleins regulate the kinetics of synaptic vesicle endocytosis. J Neurosci. 2014 Jul 9. PMID: 25009269

Reed AM, Kolodecik T, Husain SZ, Gorelick FS: Low pH enhances connexin32 degradation in the pancreatic acinar cell. Am J Physiol Gastrointest Liver Physiol. 2014 Jul 1; 2014 May 8. PMID: 24812055

Prahst C, Kasaai B, Moraes F, Jahnsen ED, Larrivee B, Villegas D, Pardanaud L, Pibouin-Fragner L, Zhang F, Zaun HC, Eichmann A, Jones EA: The H2.0-like homeobox transcription factor modulates yolk sac vascular remodeling in mouse embryos. Arterioscler Thromb Vasc Biol. 2014 Jul; 2014 Apr 24. PMID: 24764455

Gelernter J, Kranzler HR, Sherva R, Koesterer R, Almasy L, Zhao H, Farrer LA: Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways. Biol Psychiatry. 2014 Jul 1; 2013 Oct 19. PMID: 24143882

Pillai MM, Gillen AE, Yamamoto TM, Kline E, Brown J, Flory K, Hesselberth JR, Kabos P: HITS-CLIP reveals key regulators of nuclear receptor signaling in breast cancer. Breast Cancer Res Treat. 2014 Jul; 2014 Jun 7. PMID: 24906430

Sznol M: Blockade of the B7-H1/PD-1 pathway as a basis for combination anticancer therapy. Cancer J. 2014 Jul-Aug. PMID: 25098290

Kulkarni SS, Buchholz DR: Corticosteroid signaling in frog metamorphosis. Gen Comp Endocrinol. 2014 Jul 1; 2014 Apr 5. PMID: 24713447

Wang S, Choi M, Richardson AS, Reid BM, Seymen F, Yildirim M, Tuna E, Gençay K, Simmer JP, Hu JC: STIM1 and SLC24A4 Are Critical for Enamel Maturation. J Dent Res. 2014 Jul; 2014 Mar 12. PMID: 24621671

Kim JD, Jin SW: A tale of two models: mouse and zebrafish as complementary models for lymphatic studies. Mol Cells. 2014 Jul; 2014 May 23. PMID: 24854860

Kim JG, Suyama S, Koch M, Jin S, Argente-Arizon P, Argente J, Liu ZW, Zimmer MR, Jeong JK, Szigeti-Buck K, Gao Y, Garcia-Caceres C, Yi CX, Salmaso N, Vaccarino FM, Chowen J, Diano S, Dietrich MO, Tschöp MH, Horvath TL: Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding. Nat Neurosci. 2014 Jul; 2014 Jun 1. PMID: 24880214

Su B, Gao L, Baranowski C, Gillard B, Wang J, Ransom R, Ko HK, Gelman IH: A genome-wide RNAi screen identifies FOXO4 as a metastasis-suppressor through counteracting PI3K/AKT signal pathway in prostate cancer. PLoS One. 2014; 2014 Jul 1. PMID: 24983969

Lee Y, Dominy JE, Choi YJ, Jurczak M, Tolliday N, Camporez JP, Chim H, Lim JH, Ruan HB, Yang X, Vazquez F, Sicinski P, Shulman GI, Puigserver P: Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression. Nature. 2014 Jun 26; 2014 May 25. PMID: 24870244

Dufour YS, Fu X, Hernandez-Nunez L, Emonet T: Limits of feedback control in bacterial chemotaxis. PLoS Comput Biol. 2014 Jun; 2014 Jun 26. PMID: 24967937

Wu Y, O'Toole ET, Girard M, Ritter B, Messa M, Liu X, McPherson PS, Ferguson SM, De Camilli P: A dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis. Elife. 2014 Jun 24; 2014 Jun 24. PMID: 24963135

Fuentes-Mattei E, Velazquez-Torres G, Phan L, Zhang F, Chou PC, Shin JH, Choi HH, Chen JS, Zhao R, Chen J, Gully C, Carlock C, Qi Y, Zhang Y, Wu Y, Esteva FJ, Luo Y, McKeehan WL, Ensor J, Hortobagyi GN, Pusztai L, Fraser Symmans W, Lee MH, Yeung SC: Effects of obesity on transcriptomic changes and cancer hallmarks in estrogen receptor-positive breast cancer. J Natl Cancer Inst. 2014 Jul; 2014 Jun 23. PMID: 24957076

Pirruccello M, Nandez R, Idevall-Hagren O, Alcazar-Roman A, Abriola L, Berwick SA, Lucast L, Morel D, De Camilli P: Identification of inhibitors of inositol 5-phosphatases through multiple screening strategies. ACS Chem Biol. 2014 Jun 20; 2014 May 1. PMID: 24742366

Ho PC, Meeth KM, Tsui YC, Srivastava B, Bosenberg MW, Kaech SM: Immune-based antitumor effects of BRAF inhibitors rely on signaling by CD40L and IFNγ. Cancer Res. 2014 Jun 15; 2014 Apr 15. PMID: 24736544

Hedl M, Zheng S, Abraham C: The IL18RAP region disease polymorphism decreases IL-18RAP/IL-18R1/IL-1R1 expression and signaling through innate receptor-initiated pathways. J Immunol. 2014 Jun 15; 2014 May 19. PMID: 24842757

Cuda CM, Misharin AV, Gierut AK, Saber R, Haines GK 3rd, Hutcheson J, Hedrick SM, Mohan C, Budinger GS, Stehlik C, Perlman H: Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation. J Immunol. 2014 Jun 15; 2014 May 7. PMID: 24808358

Cheadle L, Biederer T: Activity-dependent regulation of dendritic complexity by semaphorin 3A through Farp1. J Neurosci. 2014 Jun 4. PMID: 24899721

Gonzalez-Angulo AM, Akcakanat A, Liu S, Green MC, Murray JL, Chen H, Palla SL, Koenig KB, Brewster AM, Valero V, Ibrahim NK, Moulder-Thompson S, Litton JK, Tarco E, Moore J, Flores P, Crawford D, Dryden MJ, Symmans WF, Sahin A, Giordano SH, Pusztai L, Do KA, Mills GB, Hortobagyi GN, Meric-Bernstam F: Open-label randomized clinical trial of standard neoadjuvant chemotherapy with paclitaxel followed by FEC versus the combination of paclitaxel and everolimus followed by FEC in women with triple receptor-negative breast cancer†. Ann Oncol. 2014 Jun; 2014 Mar 24. PMID: 24669015

Amaya MJ, Nathanson MH: Calcium signaling and the secretory activity of bile duct epithelia. Cell Calcium. 2014 Jun; 2014 Feb 12. PMID: 24612866

Huang AH, Niklason LE: Engineering of arteries in vitro. Cell Mol Life Sci. 2014 Jun; 2014 Jan 8. PMID: 24399290

Sabbatini ME, Gorelick F, Glaser S: Adenylyl cyclases in the digestive system. Cell Signal. 2014 Jun; 2014 Feb 9. PMID: 24521753

Psyrri A, Lee JW, Pectasides E, Vassilakopoulou M, Kosmidis EK, Burtness BA, Rimm DL, Wanebo HJ, Forastiere AA: Prognostic biomarkers in phase II trial of cetuximab-containing induction and chemoradiation in resectable HNSCC: Eastern cooperative oncology group E2303. Clin Cancer Res. 2014 Jun 1; 2014 Apr 3. PMID: 24700741

Rampias T, Giagini A, Siolos S, Matsuzaki H, Sasaki C, Scorilas A, Psyrri A: RAS/PI3K crosstalk and cetuximab resistance in head and neck squamous cell carcinoma. Clin Cancer Res. 2014 Jun 1; 2014 Apr 2. PMID: 24696319

Santamaria X, Taylor H: MicroRNA and gynecological reproductive diseases. Fertil Steril. 2014 Jun. PMID: 24882618

Hoque R, Farooq A, Ghani A, Gorelick F, Mehal WZ: Lactate reduces liver and pancreatic injury in Toll-like receptor- and inflammasome-mediated inflammation via GPR81-mediated suppression of innate immunity. Gastroenterology. 2014 Jun; 2014 Mar 20. PMID: 24657625

Hoang D, Broer N, Roman SA, Yao X, Abitbol N, Li F, Sosa JA, Sue GR, DeWan AT, Wong ML, Licinio J, Simpson C, Li AY, Pizzoferrato N, Narayan D: Leptin signaling and hyperparathyroidism: clinical and genetic associations. J Am Coll Surg. 2014 Jun; 2013 Nov 27. PMID: 24468228

Wang L, Velazquez H, Moeckel G, Chang J, Ham A, Lee HT, Safirstein R, Desir GV: Renalase prevents AKI independent of amine oxidase activity. J Am Soc Nephrol. 2014 Jun; 2014 Feb 7. PMID: 24511138

Moissoglu K, Kiessling V, Wan C, Hoffman BD, Norambuena A, Tamm LK, Schwartz MA: Regulation of Rac1 translocation and activation by membrane domains and their boundaries. J Cell Sci. 2014 Jun 1; 2014 Apr 2. PMID: 24695858

Sarin KY, McNiff JM, Kwok S, Kim J, Khavari PA: Activating HRAS mutation in nevus spilus. J Invest Dermatol. 2014 Jun; 2014 Jan 3. PMID: 24390138

Schwartz M: Sticking to it: tracking the paths of integrin signalling. Nat Cell Biol. 2014 Jun. PMID: 24875734

Durazzo TS, Tigelaar RE, Filler R, Hayday A, Girardi M, Edelson RL: Induction of monocyte-to-dendritic cell maturation by extracorporeal photochemotherapy: initiation via direct platelet signaling. Transfus Apher Sci. 2014 Jun; 2013 Nov 28. PMID: 24360371

Kim KH, Young BD, Bender JR: Endothelial estrogen receptor isoforms and cardiovascular disease. Mol Cell Endocrinol. 2014 May 25; 2014 Feb 11. PMID: 24530925

Levey DF, Le-Niculescu H, Frank J, Ayalew M, Jain N, Kirlin B, Learman R, Winiger E, Rodd Z, Shekhar A, Schork N, Kiefer F, Wodarz N, Müller-Myhsok B, Dahmen N, GESGA Consortium., Nöthen M, Sherva R, Farrer L, Smith AH, Kranzler HR, Rietschel M, Gelernter J, Niculescu AB: Genetic risk prediction and neurobiological understanding of alcoholism. Transl Psychiatry. 2014 May 20; 2014 May 20. PMID: 24844177

Nish SA, Schenten D, Wunderlich FT, Pope SD, Gao Y, Hoshi N, Yu S, Yan X, Lee HK, Pasman L, Brodsky I, Yordy B, Zhao H, Brüning J, Medzhitov R: T cell-intrinsic role of IL-6 signaling in primary and memory responses. Elife. 2014 May 19; 2014 May 19. PMID: 24842874

Koraishy FM, Silva C, Mason S, Wu D, Cantley LG: Hepatocyte growth factor (Hgf) stimulates low density lipoprotein receptor-related protein (Lrp) 5/6 phosphorylation and promotes canonical Wnt signaling. J Biol Chem. 2014 May 16; 2014 Apr 1. PMID: 24692544

Hedl M, Lahiri A, Ning K, Cho JH, Abraham C: Pattern recognition receptor signaling in human dendritic cells is enhanced by ICOS ligand and modulated by the Crohn's disease ICOSLG risk allele. Immunity. 2014 May 15. PMID: 24837102

Taylor A, Tang W, Bruscia EM, Zhang PX, Lin A, Gaines P, Wu D, Halene S: SRF is required for neutrophil migration in response to inflammation. Blood. 2014 May 8; 2014 Feb 26. PMID: 24574460

Choi BJ, Imlach WL, Jiao W, Wolfram V, Wu Y, Grbic M, Cela C, Baines RA, Nitabach MN, McCabe BD: Miniature neurotransmission regulates Drosophila synaptic structural maturation. Neuron. 2014 May 7. PMID: 24811381

Bartley CM, O'Keefe RA, Bordey A: FMRP S499 is phosphorylated independent of mTORC1-S6K1 activity. PLoS One. 2014; 2014 May 7. PMID: 24806451

Humphrey JD, Milewicz DM, Tellides G, Schwartz MA: Cell biology. Dysfunctional mechanosensing in aneurysms. Science. 2014 May 2. PMID: 24786066

Mehra VC, Jackson E, Zhang XM, Jiang XC, Dobrucki LW, Yu J, Bernatchez P, Sinusas AJ, Shulman GI, Sessa WC, Yarovinsky TO, Bender JR: Ceramide-activated phosphatase mediates fatty acid-induced endothelial VEGF resistance and impaired angiogenesis. Am J Pathol. 2014 May; 2014 Mar 5. PMID: 24606881

de Bruin EC, Cowell C, Warne PH, Jiang M, Saunders RE, Melnick MA, Gettinger S, Walther Z, Wurtz A, Heynen GJ, Heideman DA, Gómez-Román J, García-Castaño A, Gong Y, Ladanyi M, Varmus H, Bernards R, Smit EF, Politi K, Downward J: Reduced NF1 expression confers resistance to EGFR inhibition in lung cancer. Cancer Discov. 2014 May; 2014 Feb 17. PMID: 24535670

Fisher OS, Boggon TJ: Signaling pathways and the cerebral cavernous malformations proteins: lessons from structural biology. Cell Mol Life Sci. 2014 May; 2013 Nov 29. PMID: 24287896

Lee N, Shin MS, Kang KS, Yoo SA, Mohanty S, Montgomery RR, Shaw AC, Kang I: Human monocytes have increased IFN-γ-mediated IL-15 production with age alongside altered IFN-γ receptor signaling. Clin Immunol. 2014 May-Jun; 2014 Mar 19. PMID: 24657713

Stryjer R, Budnik D, Ebert T, Green T, Polak L, Weizman S, Spivak B: Amantadine augmentation therapy for obsessive compulsive patients resistant to SSRIs-an open-label study. Clin Neuropharmacol. 2014 May-Jun. PMID: 24824662

Kuo IY, Keeler C, Corbin R, Ćelić A, Petri ET, Hodsdon ME, Ehrlich BE: The number and location of EF hand motifs dictates the calcium dependence of polycystin-2 function. FASEB J. 2014 May; 2014 Feb 20. PMID: 24558196

Goldstein J, Fletcher S, Roth E, Wu C, Chun A, Horsley V: Calcineurin/Nfatc1 signaling links skin stem cell quiescence to hormonal signaling during pregnancy and lactation. Genes Dev. 2014 May 1; 2014 Apr 14. PMID: 24732379

Tran HT, Lee IA, Low D, Kamba A, Mizoguchi A, Shi HN, Lee CG, Elias JA, Mizoguchi E: Chitinase 3-like 1 synergistically activates IL6-mediated STAT3 phosphorylation in intestinal epithelial cells in murine models of infectious colitis. Inflamm Bowel Dis. 2014 May. PMID: 24694795

Fretz JA, Nelson T, Velazquez H, Xi Y, Moeckel GW, Horowitz MC: Early B-cell factor 1 is an essential transcription factor for postnatal glomerular maturation. Kidney Int. 2014 May; 2013 Oct 30. PMID: 24172684

Lee CM, Park JW, Cho WK, Zhou Y, Han B, Yoon PO, Chae J, Elias JA, Lee CG: Modifiers of TGF-β1 effector function as novel therapeutic targets of pulmonary fibrosis. Korean J Intern Med. 2014 May; 2014 Apr 29. PMID: 24851060

Nath S, Dancourt J, Shteyn V, Puente G, Fong WM, Nag S, Bewersdorf J, Yamamoto A, Antonny B, Melia TJ: Lipidation of the LC3/GABARAP family of autophagy proteins relies on a membrane-curvature-sensing domain in Atg3. Nat Cell Biol. 2014 May; 2014 Apr 20. PMID: 24747438

Ota KT, Liu RJ, Voleti B, Maldonado-Aviles JG, Duric V, Iwata M, Dutheil S, Duman C, Boikess S, Lewis DA, Stockmeier CA, DiLeone RJ, Rex C, Aghajanian GK, Duman RS: REDD1 is essential for stress-induced synaptic loss and depressive behavior. Nat Med. 2014 May; 2014 Apr 13. PMID: 24728411

Mehta B, Ke JB, Zhang L, Baden AD, Markowitz AL, Nayak S, Briggman KL, Zenisek D, Singer JH: Global Ca2+ signaling drives ribbon-independent synaptic transmission at rod bipolar cell synapses. J Neurosci. 2014 Apr 30. PMID: 24790194

Borghuis BG, Looger LL, Tomita S, Demb JB: Kainate receptors mediate signaling in both transient and sustained OFF bipolar cell pathways in mouse retina. J Neurosci. 2014 Apr 30. PMID: 24790183

Tang WH, Stitham J, Jin Y, Liu R, Lee SH, Du J, Atteya G, Gleim S, Spollett G, Martin K, Hwa J: Aldose reductase-mediated phosphorylation of p53 leads to mitochondrial dysfunction and damage in diabetic platelets. Circulation. 2014 Apr 15; 2014 Jan 28. PMID: 24474649

Chen PY, Qin L, Zhuang ZW, Tellides G, Lax I, Schlessinger J, Simons M: The docking protein FRS2α is a critical regulator of VEGF receptors signaling. Proc Natl Acad Sci U S A. 2014 Apr 15; 2014 Apr 2. PMID: 24706887

Guo YE, Riley KJ, Iwasaki A, Steitz JA: Alternative capture of noncoding RNAs or protein-coding genes by herpesviruses to alter host T cell function. Mol Cell. 2014 Apr 10. PMID: 24725595

Willinger T, Ferguson SM, Pereira JP, De Camilli P, Flavell RA: Dynamin 2-dependent endocytosis is required for sustained S1PR1 signaling. J Exp Med. 2014 Apr 7; 2014 Mar 17. PMID: 24638168

Shi W, Balazs B, Györffy B, Jiang T, Symmans WF, Hatzis C, Pusztai L: Combined analysis of gene expression, DNA copy number, and mutation profiling data to display biological process anomalies in individual breast cancers. Breast Cancer Res Treat. 2014 Apr; 2014 Mar 12. PMID: 24619174

Rawling DC, Pyle AM: Parts, assembly and operation of the RIG-I family of motors. Curr Opin Struct Biol. 2014 Apr; 2013 Dec 20. PMID: 24878341

Ruddle NH: Lymphotoxin and TNF: how it all began-a tribute to the travelers. Cytokine Growth Factor Rev. 2014 Apr; 2014 Feb 12. PMID: 24636534

Duman RS: Neurobiology of stress, depression, and rapid acting antidepressants: remodeling synaptic connections. Depress Anxiety. 2014 Apr; 2014 Mar 10. PMID: 24616149

Lee MY, Skoura A, Park EJ, Landskroner-Eiger S, Jozsef L, Luciano AK, Murata T, Pasula S, Dong Y, Bouaouina M, Calderwood DA, Ferguson SM, De Camilli P, Sessa WC: Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis. Development. 2014 Apr; 2014 Mar 5. PMID: 24598168

Gattu AK, Birkenfeld AL, Iwakiri Y, Jay S, Saltzman M, Doll J, Protiva P, Samuel VT, Crawford SE, Chung C: Pigment epithelium-derived factor (PEDF) suppresses IL-1β-mediated c-Jun N-terminal kinase (JNK) activation to improve hepatocyte insulin signaling. Endocrinology. 2014 Apr; 2014 Jan 23. PMID: 24456163

Mattace Raso G, Santoro A, Russo R, Simeoli R, Paciello O, Di Carlo C, Diano S, Calignano A, Meli R: Palmitoylethanolamide prevents metabolic alterations and restores leptin sensitivity in ovariectomized rats. Endocrinology. 2014 Apr; 2014 Jan 15. PMID: 24428531

Zhang W, Devi SP, Tomita S, Howe JR: Auxiliary proteins promote modal gating of AMPA- and kainate-type glutamate receptors. Eur J Neurosci. 2014 Apr. PMID: 24712993

Menard L, Cantaert T, Chamberlain N, Tangye SG, Riminton S, Church JA, Klion A, Cunningham-Rundles C, Nichols KE, Meffre E: Signaling lymphocytic activation molecule (SLAM)/SLAM-associated protein pathway regulates human B-cell tolerance. J Allergy Clin Immunol. 2014 Apr; 2013 Dec 25. PMID: 24373350

Morell CM, Strazzabosco M: Notch signaling and new therapeutic options in liver disease. J Hepatol. 2014 Apr; 2013 Dec 3. PMID: 24308992

Levinsohn JL, Teng J, Craiglow BG, Loring EC, Burrow TA, Mane SS, Overton JD, Lifton RP, McNiff JM, Lucky AW, Choate KA: Somatic HRAS p.G12S mutation causes woolly hair and epidermal nevi. J Invest Dermatol. 2014 Apr; 2013 Oct 15. PMID: 24129065

van den Pol AN, Ding S, Robek MD: Long-distance interferon signaling within the brain blocks virus spread. J Virol. 2014 Apr; 2014 Jan 15. PMID: 24429359

Bezbradica JS, Rosenstein RK, DeMarco RA, Brodsky I, Medzhitov R: A role for the ITAM signaling module in specifying cytokine-receptor functions. Nat Immunol. 2014 Apr; 2014 Mar 9. PMID: 24608040

Tufro A: Semaphorin3a signaling, podocyte shape, and glomerular disease. Pediatr Nephrol. 2014 Apr; 2014 Jan 26. PMID: 24464477

Zito G, Saotome I, Liu Z, Ferro EG, Sun TY, Nguyen DX, Bilguvar K, Ko CJ, Greco V: Spontaneous tumour regression in keratoacanthomas is driven by Wnt/retinoic acid signalling cross-talk. Nat Commun. 2014 Mar 26; 2014 Mar 26. PMID: 24667544

Ma X, Wang S, Do T, Song X, Inaba M, Nishimoto Y, Liu LP, Gao Y, Mao Y, Li H, McDowell W, Park J, Malanowski K, Peak A, Perera A, Li H, Gaudenz K, Haug J, Yamashita Y, Lin H, Ni JQ, Xie T: Piwi is required in multiple cell types to control germline stem cell lineage development in the Drosophila ovary. PLoS One. 2014; 2014 Mar 21. PMID: 24658126

Deschene ER, Myung P, Rompolas P, Zito G, Sun TY, Taketo MM, Saotome I, Greco V: β-Catenin activation regulates tissue growth non-cell autonomously in the hair stem cell niche. Science. 2014 Mar 21. PMID: 24653033

Ray JP, Marshall HD, Laidlaw BJ, Staron MM, Kaech SM, Craft J: Transcription factor STAT3 and type I interferons are corepressive insulators for differentiation of follicular helper and T helper 1 cells. Immunity. 2014 Mar 20; 2014 Mar 13. PMID: 24631156

Zucker SN, Fink EE, Bagati A, Mannava S, Bianchi-Smiraglia A, Bogner PN, Wawrzyniak JA, Foley C, Leonova KI, Grimm MJ, Moparthy K, Ionov Y, Wang J, Liu S, Sexton S, Kandel ES, Bakin AV, Zhang Y, Kaminski N, Segal BH, Nikiforov MA: Nrf2 amplifies oxidative stress via induction of Klf9. Mol Cell. 2014 Mar 20; 2014 Mar 6. PMID: 24613345

Huang X, Yang P, Ouyang X, Chen L, Deng XW: Photoactivated UVR8-COP1 module determines photomorphogenic UV-B signaling output in Arabidopsis. PLoS Genet. 2014 Mar; 2014 Mar 20. PMID: 24651064

Esquibies AE, Karihaloo A, Quaggin SE, Bazzy-Asaad A, Cantley LG: Heparin binding VEGF isoforms attenuate hyperoxic embryonic lung growth retardation via a FLK1-neuropilin-1-PKC dependent pathway. Respir Res. 2014 Mar 19; 2014 Mar 19. PMID: 24641672

Cao Z, Ding BS, Guo P, Lee SB, Butler JM, Casey SC, Simons M, Tam W, Felsher DW, Shido K, Rafii A, Scandura JM, Rafii S: Angiocrine factors deployed by tumor vascular niche induce B cell lymphoma invasiveness and chemoresistance. Cancer Cell. 2014 Mar 17. PMID: 24651014

Fan HC, Fernández-Hernando C, Lai JH: Protein kinase C isoforms in atherosclerosis: pro- or anti-inflammatory? Biochem Pharmacol. 2014 Mar 15; 2014 Jan 16. PMID: 24440741

Chamorro-Jorganes A, Araldi E, Rotllan N, Cirera-Salinas D, Suárez Y: Autoregulation of glypican-1 by intronic microRNA-149 fine tunes the angiogenic response to FGF2 in human endothelial cells. J Cell Sci. 2014 Mar 15; 2014 Jan 24. PMID: 24463821

Park SJ, Kim IJ, Looger LL, Demb JB, Borghuis BG: Excitatory synaptic inputs to mouse on-off direction-selective retinal ganglion cells lack direction tuning. J Neurosci. 2014 Mar 12. PMID: 24623775

Monsey MS, Boyle LM, Zhang ML, Nguyen CP, Kronman HG, Ota KT, Duman RS, Taylor JR, Schafe GE: Chronic corticosterone exposure persistently elevates the expression of memory-related genes in the lateral amygdala and enhances the consolidation of a Pavlovian fear memory. PLoS One. 2014; 2014 Mar 11. PMID: 24618807

Du X, Dong Y, Shi H, Li J, Kong S, Shi D, Sun LV, Xu T, Deng K, Tao W: Mst1 and mst2 are essential regulators of trophoblast differentiation and placenta morphogenesis. PLoS One. 2014; 2014 Mar 4. PMID: 24595170

Buse J, Kirschbaum C, Leckman JF, Münchau A, Roessner V: The Modulating Role of Stress in the Onset and Course of Tourette's Syndrome: A Review. Behav Modif. 2014 Mar; 2014 Feb 10. PMID: 24516255

Dainiak N: Potential for new medical countermeasures for radiation injury by targeting the Hedgehog signaling pathway. Bone Marrow Transplant. 2014 Mar. PMID: 24595105

Ma X, Li W, Yu H, Yang Y, Li M, Xue L, Xu T: Bendless modulates JNK-mediated cell death and migration in Drosophila. Cell Death Differ. 2014 Mar; 2013 Oct 25. PMID: 24162658

Gonzalez AL, Berger CL, Remington J, Girardi M, Tigelaar RE, Edelson RL: Integrin-driven monocyte to dendritic cell conversion in modified extracorporeal photochemotherapy. Clin Exp Immunol. 2014 Mar. PMID: 24188174

Schlessinger J: Receptor tyrosine kinases: legacy of the first two decades. Cold Spring Harb Perspect Biol. 2014 Mar 1; 2014 Mar 1. PMID: 24591517

Louvi A, Nishimura S, Günel M: Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration. Development. 2014 Mar. PMID: 24595293

Szepietowska B, Horvath TL, Sherwin RS: Role of synaptic plasticity and EphA5-ephrinA5 interaction within the ventromedial hypothalamus in response to recurrent hypoglycemia. Diabetes. 2014 Mar; 2013 Nov 12. PMID: 24222347

Duman RS: Pathophysiology of depression and innovative treatments: remodeling glutamatergic synaptic connections. Dialogues Clin Neurosci. 2014 Mar. PMID: 24733968

Black JA, Vasylyev D, Dib-Hajj SD, Waxman SG: Nav1.9 expression in magnocellular neurosecretory cells of supraoptic nucleus. Exp Neurol. 2014 Mar; 2014 Jan 11. PMID: 24424281

Mori DN, Kreisel D, Fullerton JN, Gilroy DW, Goldstein DR: Inflammatory triggers of acute rejection of organ allografts. Immunol Rev. 2014 Mar. PMID: 24517430

Wang X, Marr AK, Breitkopf T, Leung G, Hao J, Wang E, Kwong N, Akhoundsadegh N, Chen L, Mui A, Carr N, Warnock GL, Shapiro J, McElwee KJ: Hair follicle mesenchyme-associated PD-L1 regulates T-cell activation induced apoptosis: a potential mechanism of immune privilege. J Invest Dermatol. 2014 Mar; 2013 Sep 4. PMID: 24005055

Kim JD, Kim J: Alk3/Alk3b and Smad5 mediate BMP signaling during lymphatic development in zebrafish. Mol Cells. 2014 Mar; 2014 Mar 6. PMID: 24608800

Maldonado-Avilés JG, Dileone RJ: Inhaling: endocannabinoids and food intake. Nat Neurosci. 2014 Mar. PMID: 24569827

Choi J, Landrette SF, Wang T, Evans P, Bacchiocchi A, Bjornson R, Cheng E, Stiegler AL, Gathiaka S, Acevedo O, Boggon TJ, Krauthammer M, Halaban R, Xu T: Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors. Pigment Cell Melanoma Res. 2014 Mar; 2014 Jan 6. PMID: 24283590

Xu D, Li J, Gangappa SN, Hettiarachchi C, Lin F, Andersson MX, Jiang Y, Deng XW, Holm M: Convergence of Light and ABA signaling on the ABI5 promoter. PLoS Genet. 2014 Feb; 2014 Feb 27. PMID: 24586210

Pulloor NK, Nair S, McCaffrey K, Kostic AD, Bist P, Weaver JD, Riley AM, Tyagi R, Uchil PD, York JD, Snyder SH, García-Sastre A, Potter BV, Lin R, Shears SB, Xavier RJ, Krishnan MN: Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response. PLoS Pathog. 2014 Feb; 2014 Feb 27. PMID: 24586175

Xue P, Zhao Y, Liu Y, Yuan Q, Xiong C, Ruan J: A novel compound RY10-4 induces apoptosis and inhibits invasion via inhibiting STAT3 through ERK-, p38-dependent pathways in human lung adenocarcinoma A549 cells. Chem Biol Interact. 2014 Feb 25; 2013 Dec 1. PMID: 24300195

Yan D, Neumüller RA, Buckner M, Ayers K, Li H, Hu Y, Yang-Zhou D, Pan L, Wang X, Kelley C, Vinayagam A, Binari R, Randklev S, Perkins LA, Xie T, Cooley L, Perrimon N: A regulatory network of Drosophila germline stem cell self-renewal. Dev Cell. 2014 Feb 24. PMID: 24576427

Yang Y, Jin X, Jiang C: S-glutathionylation of ion channels: insights into the regulation of channel functions, thiol modification crosstalk, and mechanosensing. Antioxid Redox Signal. 2014 Feb 20; 2013 Aug 20. PMID: 23834398

Forloni M, Dogra SK, Dong Y, Conte D Jr, Ou J, Zhu LJ, Deng A, Mahalingam M, Green MR, Wajapeyee N: miR-146a promotes the initiation and progression of melanoma by activating Notch signaling. Elife. 2014 Feb 18; 2014 Feb 18. PMID: 24550252

Eroglu B, Min JN, Zhang Y, Szurek E, Moskophidis D, Eroglu A, Mivechi NF: An essential role for heat shock transcription factor binding protein 1 (HSBP1) during early embryonic development. Dev Biol. 2014 Feb 15; 2013 Dec 28. PMID: 24380799

Thompson PD, Sakwe A, Koumangoye R, Yarbrough WG, Ochieng J, Marshall DR: Alpha-2 Heremans Schmid Glycoprotein (AHSG) modulates signaling pathways in head and neck squamous cell carcinoma cell line SQ20B. Exp Cell Res. 2014 Feb 15; 2013 Dec 12. PMID: 24332981

Draheim KM, Fisher OS, Boggon TJ, Calderwood DA: Cerebral cavernous malformation proteins at a glance. J Cell Sci. 2014 Feb 15; 2014 Jan 30. PMID: 24481819

Bonham KS, Orzalli MH, Hayashi K, Wolf AI, Glanemann C, Weninger W, Iwasaki A, Knipe DM, Kagan JC: A promiscuous lipid-binding protein diversifies the subcellular sites of toll-like receptor signal transduction. Cell. 2014 Feb 13. PMID: 24529375

Scafidi J, Hammond TR, Scafidi S, Ritter J, Jablonska B, Roncal M, Szigeti-Buck K, Coman D, Huang Y, McCarter RJ Jr, Hyder F, Horvath TL, Gallo V: Intranasal epidermal growth factor treatment rescues neonatal brain injury. Nature. 2014 Feb 13; 2013 Dec 25. PMID: 24390343

Feliciano DM, Zhang S, Nasrallah CM, Lisgo SN, Bordey A: Embryonic cerebrospinal fluid nanovesicles carry evolutionarily conserved molecules and promote neural stem cell amplification. PLoS One. 2014; 2014 Feb 12. PMID: 24533152

Morse EM, Brahme NN, Calderwood DA: Integrin cytoplasmic tail interactions. Biochemistry. 2014 Feb 11; 2014 Jan 27. PMID: 24467163

Byrne AB, Walradt T, Gardner KE, Hubbert A, Reinke V, Hammarlund M: Insulin/IGF1 signaling inhibits age-dependent axon regeneration. Neuron. 2014 Feb 5; 2014 Jan 16. PMID: 24440228

Li F, Sun J, Wang D, Bai S, Clarke AK, Holm M: The B-box family gene STO (BBX24) in Arabidopsis thaliana regulates flowering time in different pathways. PLoS One. 2014; 2014 Feb 3. PMID: 24498334

Kim JD, Kang Y, Kim J, Papangeli I, Kang H, Wu J, Park H, Nadelmann E, Rockson SG, Chun HJ, Jin SW: Essential role of Apelin signaling during lymphatic development in zebrafish. Arterioscler Thromb Vasc Biol. 2014 Feb; 2013 Dec 5. PMID: 24311379

Charbonneau B, Block MS, Bamlet WR, Vierkant RA, Kalli KR, Fogarty Z, Rider DN, Sellers TA, Tworoger SS, Poole E, Risch HA, Salvesen HB, Kiemeney LA, Baglietto L, Giles GG, Severi G, Trabert B, Wentzensen N, Chenevix-Trench G, for AOCS/ACS group., Whittemore AS, Sieh W, Chang-Claude J, Bandera EV, Orlow I, Terry K, Goodman MT, Thompson PJ, Cook LS, Rossing MA, Ness RB, Narod SA, Kupryjanczyk J, Lu K, Butzow R, Dörk T, Pejovic T, Campbell I, Le ND, Bunker CH, Bogdanova N, Runnebaum IB, Eccles D, Paul J, Wu AH, Gayther SA, Hogdall E, Heitz F, Kaye SB, Karlan BY, Anton-Culver H, Gronwald J, Hogdall CK, Lambrechts D, Fasching PA, Menon U, Schildkraut J, Pearce CL, Levine DA, Kjaer SK, Cramer D, Flanagan JM, Phelan CM, Brown R, Massuger LF, Song H, Doherty JA, Krakstad C, Liang D, Odunsi K, Berchuck A, Jensen A, Lubinski J, Nevanlinna H, Bean YT, Lurie G, Ziogas A, Walsh C, Despierre E, Brinton L, Hein A, Rudolph A, Dansonka-Mieszkowska A, Olson SH, Harter P, Tyrer J, Vitonis AF, Brooks-Wilson A, Aben KK, Pike MC, Ramus SJ, Wik E, Cybulski C, Lin J, Sucheston L, Edwards R, McGuire V, Lester J, du Bois A, Lundvall L, Wang-Gohrke S, Szafron LM, Lambrechts S, Yang H, Beckmann MW, Pelttari LM, Van Altena AM, van den Berg D, Halle MK, Gentry-Maharaj A, Schwaab I, Chandran U, Menkiszak J, Ekici AB, Wilkens LR, Leminen A, Modugno F, Friel G, Rothstein JH, Vergote I, Garcia-Closas M, Hildebrandt MA, Sobiczewski P, Kelemen LE, Pharoah PD, Moysich K, Knutson KL, Cunningham JM, Fridley BL, Goode EL: Risk of ovarian cancer and the NF-κB pathway: genetic association with IL1A and TNFSF10. Cancer Res. 2014 Feb 1; 2013 Nov 22. PMID: 24272484

Assis DN, Leng L, Du X, Zhang CK, Grieb G, Merk M, Garcia AB, McCrann C, Chapiro J, Meinhardt A, Mizue Y, Nikolic-Paterson DJ, Bernhagen J, Kaplan MM, Zhao H, Boyer JL, Bucala R: The role of macrophage migration inhibitory factor in autoimmune liver disease. Hepatology. 2014 Feb; 2013 Dec 20. PMID: 23913513

Chiodi V, Mallozzi C, Ferrante A, Chen JF, Lombroso PJ, Di Stasi AM, Popoli P, Domenici MR: Cocaine-induced changes of synaptic transmission in the striatum are modulated by adenosine A2A receptors and involve the tyrosine phosphatase STEP. Neuropsychopharmacology. 2014 Feb; 2013 Aug 30. PMID: 23989619

Seo KI, Lee JH, Nezames CD, Zhong S, Song E, Byun MO, Deng XW: ABD1 is an Arabidopsis DCAF substrate receptor for CUL4-DDB1-based E3 ligases that acts as a negative regulator of abscisic acid signaling. Plant Cell. 2014 Feb; 2014 Feb 21. PMID: 24563203

Mehrotra D, Wu J, Papangeli I, Chun HJ: Endothelium as a gatekeeper of fatty acid transport. Trends Endocrinol Metab. 2014 Feb; 2013 Dec 3. PMID: 24315207

Vogt MC, Paeger L, Hess S, Steculorum SM, Awazawa M, Hampel B, Neupert S, Nicholls HT, Mauer J, Hausen AC, Predel R, Kloppenburg P, Horvath TL, Brüning JC: Neonatal insulin action impairs hypothalamic neurocircuit formation in response to maternal high-fat feeding. Cell. 2014 Jan 30; 2014 Jan 23. PMID: 24462248

Wittkowski KM, Sonakya V, Bigio B, Tonn MK, Shic F, Ascano M, Nasca C, Gold-Von Simson G: A novel computational biostatistics approach implies impaired dephosphorylation of growth factor receptors as associated with severity of autism. Transl Psychiatry. 2014 Jan 28; 2014 Jan 28. PMID: 24473445

Chakraborty R, Bhullar RP, Dakshinamurti S, Hwa J, Chelikani P: Inverse agonism of SQ 29,548 and Ramatroban on Thromboxane A2 receptor. PLoS One. 2014; 2014 Jan 23. PMID: 24465800

Schenten D, Nish SA, Yu S, Yan X, Lee HK, Brodsky I, Pasman L, Yordy B, Wunderlich FT, Brüning JC, Zhao H, Medzhitov R: Signaling through the adaptor molecule MyD88 in CD4+ T cells is required to overcome suppression by regulatory T cells. Immunity. 2014 Jan 16. PMID: 24439266

Whiteus C, Freitas C, Grutzendler J: Perturbed neural activity disrupts cerebral angiogenesis during a postnatal critical period. Nature. 2014 Jan 16; 2013 Dec 4. PMID: 24305053

Narasimhan S, Rajeevan N, Liu L, Zhao YO, Heisig J, Pan J, Eppler-Epstein R, Deponte K, Fish D, Fikrig E: Gut microbiota of the tick vector Ixodes scapularis modulate colonization of the Lyme disease spirochete. Cell Host Microbe. 2014 Jan 15. PMID: 24439898

Wu X, Chi RJ, Baskin JM, Lucast L, Burd CG, De Camilli P, Reinisch KM: Structural insights into assembly and regulation of the plasma membrane phosphatidylinositol 4-kinase complex. Dev Cell. 2014 Jan 13; 2013 Dec 19. PMID: 24360784

Nix P, Hammarlund M, Hauth L, Lachnit M, Jorgensen EM, Bastiani M: Axon regeneration genes identified by RNAi screening in C. elegans. J Neurosci. 2014 Jan 8. PMID: 24403161

Thompson AM, Martin KA, Rzucidlo EM: Resveratrol induces vascular smooth muscle cell differentiation through stimulation of SirT1 and AMPK. PLoS One. 2014; 2014 Jan 8. PMID: 24416418

Harrison MS, Hung CS, Liu TT, Christiano R, Walther TC, Burd CG: A mechanism for retromer endosomal coat complex assembly with cargo. Proc Natl Acad Sci U S A. 2014 Jan 7; 2013 Dec 16. PMID: 24344282

Dunworth WP, Cardona-Costa J, Bozkulak EC, Kim JD, Meadows S, Fischer JC, Wang Y, Cleaver O, Qyang Y, Ober EA, Jin SW: Bone morphogenetic protein 2 signaling negatively modulates lymphatic development in vertebrate embryos. Circ Res. 2014 Jan 3; 2013 Oct 11. PMID: 24122719

Ju R, Zhuang ZW, Zhang J, Lanahan AA, Kyriakides T, Sessa WC, Simons M: Angiopoietin-2 secretion by endothelial cell exosomes: regulation by the phosphatidylinositol 3-kinase (PI3K)/Akt/endothelial nitric oxide synthase (eNOS) and syndecan-4/syntenin pathways. J Biol Chem. 2014 Jan 3; 2013 Nov 14. PMID: 24235146

Ding BS, Cao Z, Lis R, Nolan DJ, Guo P, Simons M, Penfold ME, Shido K, Rabbany SY, Rafii S: Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis. Nature. 2014 Jan 2; 2013 Nov 20. PMID: 24256728

Sternberg CN, Petrylak DP, Madan RA, Parker C: Progress in the treatment of advanced prostate cancer. Am Soc Clin Oncol Educ Book. 2014. PMID: 24857068

Henao-Mejia J, Elinav E, Thaiss CA, Flavell RA: Inflammasomes and metabolic disease. Annu Rev Physiol. 2014; 2013 Nov 21. PMID: 24274736

Chen X, Zhou HJ, Huang Q, Lu L, Min W: Novel action and mechanism of auranofin in inhibition of vascular endothelial growth factor receptor-3-dependent lymphangiogenesis. Anticancer Agents Med Chem. 2014. PMID: 24913775

Sekine Y: Adaptor protein STAP-2 modulates cellular signaling in immune systems. Biol Pharm Bull. 2014. PMID: 24492713

Hedhli N, Kalinowski A, S Russell K: Cardiovascular effects of neuregulin-1/ErbB signaling: role in vascular signaling and angiogenesis. Curr Pharm Des. 2014. PMID: 24283954

Schneider ER, Anderson EO, Gracheva EO, Bagriantsev SN: Temperature sensitivity of two-pore (K2P) potassium channels. Curr Top Membr. 2014. PMID: 25366235

Mis EK, Liem KF Jr, Kong Y, Schwartz NB, Domowicz M, Weatherbee SD: Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol. 2014 Jan 1; 2013 Oct 23. PMID: 24161523

Lopez-Ramirez MA, Nicoli S: Role of miRNAs and epigenetics in neural stem cell fate determination. Epigenetics. 2014 Jan; 2013 Dec 16. PMID: 24342893

Amaya MJ, Oliveira AG, Guimarães ES, Casteluber MC, Carvalho SM, Andrade LM, Pinto MC, Mennone A, Oliveira CA, Resende RR, Menezes GB, Nathanson MH, Leite MF: The insulin receptor translocates to the nucleus to regulate cell proliferation in liver. Hepatology. 2014 Jan; 2013 Jul 29. PMID: 23839970

Wallner PE, Anscher MS, Barker CA, Bassetti M, Bristow RG, Cha YI, Dicker AP, Formenti SC, Graves EE, Hahn SM, Hei TK, Kimmelman AC, Kirsch DG, Kozak KR, Lawrence TS, Marples B, McBride WH, Mikkelsen RB, Park CC, Weidhaas JB, Zietman AL, Steinberg M: Current status and recommendations for the future of research, teaching, and testing in the biological sciences of radiation oncology: report of the American Society for Radiation Oncology Cancer Biology/Radiation Biology Task Force, executive summary. Int J Radiat Oncol Biol Phys. 2014 Jan 1; 2013 Nov 15. PMID: 24246724

Talman AM, Chong R, Chia J, Svitkina T, Agaisse H: Actin network disassembly powers dissemination of Listeria monocytogenes. J Cell Sci. 2014 Jan 1; 2013 Oct 23. PMID: 24155331

Schroeder EA, Shadel GS: Crosstalk between mitochondrial stress signals regulates yeast chronological lifespan. Mech Ageing Dev. 2014 Jan; 2013 Dec 25. PMID: 24373996

Begum A, Lin Q, Yu C, Kim Y, Yun Z: Interaction of delta-like 1 homolog (Drosophila) with prohibitins and its impact on tumor cell clonogenicity. Mol Cancer Res. 2014 Jan; 2013 Nov 18. PMID: 24249679

LaMotte RH, Dong X, Ringkamp M: Sensory neurons and circuits mediating itch. Nat Rev Neurosci. 2014 Jan. PMID: 24356071

Kwon SH, Scheinost D, Lacadie C, Benjamin J, Myers EH, Qiu M, Schneider KC, Rothman DL, Constable RT, Ment LR: GABA, resting-state connectivity and the developing brain. Neonatology. 2014; 2014 Jun 26. PMID: 24970028

Duman RS, Aghajanian GK: Neurobiology of rapid acting antidepressants: role of BDNF and GSK-3β. Neuropsychopharmacology. 2014 Jan. PMID: 24317309

Arterbery AS, Bogue CW: Endodermal and mesenchymal cross talk: a crossroad for the maturation of foregut organs. Pediatr Res. 2014 Jan; 2013 Nov 5. PMID: 24192700

Heger K, Fierens K, Vahl JC, Aszodi A, Peschke K, Schenten D, Hammad H, Beyaert R, Saur D, van Loo G, Roers A, Lambrecht BN, Kool M, Schmidt-Supprian M: A20-deficient mast cells exacerbate inflammatory responses in vivo. PLoS Biol. 2014 Jan; 2014 Jan 14. PMID: 24453940

Ding S, Khoury-Hanold W, Iwasaki A, Robek MD: Epigenetic reprogramming of the type III interferon response potentiates antiviral activity and suppresses tumor growth. PLoS Biol. 2014 Jan; 2014 Jan 7. PMID: 24409098

Arnsten AF, Jin LE: Molecular influences on working memory circuits in dorsolateral prefrontal cortex. Prog Mol Biol Transl Sci. 2014. PMID: 24484703

Donnelly DF, Kim I, Mulligan EM, Carroll JL: Non-additive interactions between mitochondrial complex IV blockers and hypoxia in rat carotid body responses. Respir Physiol Neurobiol. 2014 Jan 1; 2013 Oct 2. PMID: 24096081

Vuga LJ, Milosevic J, Pandit K, Ben-Yehudah A, Chu Y, Richards T, Sciurba J, Myerburg M, Zhang Y, Parwani AV, Gibson KF, Kaminski N: Cartilage oligomeric matrix protein in idiopathic pulmonary fibrosis. PLoS One. 2013; 2013 Dec 20. PMID: 24376648

Boskovski MT, Yuan S, Pedersen NB, Goth CK, Makova S, Clausen H, Brueckner M, Khokha MK: The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality. Nature. 2013 Dec 19; 2013 Nov 13. PMID: 24226769

Gubanova E, Issaeva N, Gokturk C, Djureinovic T, Helleday T: SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways. Cell Cycle. 2013 Dec 15; 2013 Oct 4. PMID: 24107632

Hanawalt PC: The awakening of DNA repair at Yale. Yale J Biol Med. 2013 Dec 13; 2013 Dec 13. PMID: 24348216

Kupfer GM: Fanconi anemia: a signal transduction and DNA repair pathway. Yale J Biol Med. 2013 Dec 13; 2013 Dec 13. PMID: 24348213

Jensen RB: BRCA2: one small step for DNA repair, one giant protein purified. Yale J Biol Med. 2013 Dec 13; 2013 Dec 13. PMID: 24348212

Rogers FA, Tiwari MK: Triplex-induced DNA damage response. Yale J Biol Med. 2013 Dec 13; 2013 Dec 13. PMID: 24348211

Daley JM, Kwon Y, Niu H, Sung P: Investigations of homologous recombination pathways and their regulation. Yale J Biol Med. 2013 Dec 13; 2013 Dec 13. PMID: 24348209

Glazer PM, Hegan DC, Lu Y, Czochor J, Scanlon SE: Hypoxia and DNA repair. Yale J Biol Med. 2013 Dec 13; 2013 Dec 13. PMID: 24348208

Lombaert IM, Abrams SR, Li L, Eswarakumar VP, Sethi AJ, Witt RL, Hoffman MP: Combined KIT and FGFR2b signaling regulates epithelial progenitor expansion during organogenesis. Stem Cell Reports. 2013; 2013 Dec 12. PMID: 24371813

Lin Q, Huang Y, Booth CJ, Haase VH, Johnson RS, Celeste Simon M, Giordano FJ, Yun Z: Activation of hypoxia-inducible factor-2 in adipocytes results in pathological cardiac hypertrophy. J Am Heart Assoc. 2013 Dec 10; 2013 Dec 10. PMID: 24326162

Marcelo KL, Sills TM, Coskun S, Vasavada H, Sanglikar S, Goldie LC, Hirschi KK: Hemogenic endothelial cell specification requires c-Kit, Notch signaling, and p27-mediated cell-cycle control. Dev Cell. 2013 Dec 9. PMID: 24331925

Jane-Wit D, Manes TD, Yi T, Qin L, Clark P, Kirkiles-Smith NC, Abrahimi P, Devalliere J, Moeckel G, Kulkarni S, Tellides G, Pober JS: Alloantibody and complement promote T cell-mediated cardiac allograft vasculopathy through noncanonical nuclear factor-κB signaling in endothelial cells. Circulation. 2013 Dec 3; 2013 Sep 17. PMID: 24045046

Gamo NJ, Duque A, Paspalas CD, Kata A, Fine R, Boven L, Bryan C, Lo T, Anighoro K, Bermudez L, Peng K, Annor A, Raja A, Mansson E, Taylor SR, Patel K, Simen AA, Arnsten AF: Role of disrupted in schizophrenia 1 (DISC1) in stress-induced prefrontal cognitive dysfunction. Transl Psychiatry. 2013 Dec 3; 2013 Dec 3. PMID: 24301646

Chang WG, Andrejecsk JW, Kluger MS, Saltzman WM, Pober JS: Pericytes modulate endothelial sprouting. Cardiovasc Res. 2013 Dec 1; 2013 Sep 16. PMID: 24042014

Ruan HB, Nie Y, Yang X: Regulation of protein degradation by O-GlcNAcylation: crosstalk with ubiquitination. Mol Cell Proteomics. 2013 Dec; 2013 Jul 3. PMID: 23824911

Nelson JW, Sudarsan N, Furukawa K, Weinberg Z, Wang JX, Breaker RR: Riboswitches in eubacteria sense the second messenger c-di-AMP. Nat Chem Biol. 2013 Dec; 2013 Oct 20. PMID: 24141192

You F, Wang P, Yang L, Yang G, Zhao YO, Qian F, Walker W, Sutton R, Montgomery R, Lin R, Iwasaki A, Fikrig E: ELF4 is critical for induction of type I interferon and the host antiviral response. Nat Immunol. 2013 Dec; 2013 Nov 3. PMID: 24185615

Ivanov SS, Roy CR: Pathogen signatures activate a ubiquitination pathway that modulates the function of the metabolic checkpoint kinase mTOR. Nat Immunol. 2013 Dec; 2013 Oct 13. PMID: 24121838

Ottoboni L, Frohlich IY, Lee M, Healy BC, Keenan BT, Xia Z, Chitnis T, Guttmann CR, Khoury SJ, Weiner HL, Hafler DA, De Jager PL: Clinical relevance and functional consequences of the TNFRSF1A multiple sclerosis locus. Neurology. 2013 Nov 26; 2013 Oct 30. PMID: 24174586

Gan X, Wang C, Patel M, Kreutz B, Zhou M, Kozasa T, Wu D: Different Raf protein kinases mediate different signaling pathways to stimulate E3 ligase RFFL gene expression in cell migration regulation. J Biol Chem. 2013 Nov 22; 2013 Oct 10. PMID: 24114843

Giovinazzo F, Schimmack S, Svejda B, Alaimo D, Pfragner R, Modlin I, Kidd M: Chromogranin A and its fragments as regulators of small intestinal neuroendocrine neoplasm proliferation. PLoS One. 2013; 2013 Nov 19. PMID: 24260544

Voleti B, Navarria A, Liu RJ, Banasr M, Li N, Terwilliger R, Sanacora G, Eid T, Aghajanian G, Duman RS: Scopolamine rapidly increases mammalian target of rapamycin complex 1 signaling, synaptogenesis, and antidepressant behavioral responses. Biol Psychiatry. 2013 Nov 15; 2013 Jun 14. PMID: 23751205

Chen D, Chen Z, Park C, Centrella M, McCarthy T, Chen L, Al-Omari A, Moeckel GW: Aldosterone stimulates fibronectin synthesis in renal fibroblasts through mineralocorticoid receptor-dependent and independent mechanisms. Gene. 2013 Nov 15; 2013 Aug 30. PMID: 23994292

Jouret F, Wu J, Hull M, Rajendran V, Mayr B, Schöfl C, Geibel J, Caplan MJ: Activation of the Ca²+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membrane. J Cell Sci. 2013 Nov 15; 2013 Sep 6. PMID: 24013548

Berke B, Wittnam J, McNeill E, Van Vactor DL, Keshishian H: Retrograde BMP signaling at the synapse: a permissive signal for synapse maturation and activity-dependent plasticity. J Neurosci. 2013 Nov 6. PMID: 24198381

Deb I, Manhas N, Poddar R, Rajagopal S, Allan AM, Lombroso PJ, Rosenberg GA, Candelario-Jalil E, Paul S: Neuroprotective role of a brain-enriched tyrosine phosphatase, STEP, in focal cerebral ischemia. J Neurosci. 2013 Nov 6. PMID: 24198371

Shibata S, Rinehart J, Zhang J, Moeckel G, Castañeda-Bueno M, Stiegler AL, Boggon TJ, Gamba G, Lifton RP: Mineralocorticoid receptor phosphorylation regulates ligand binding and renal response to volume depletion and hyperkalemia. Cell Metab. 2013 Nov 5. PMID: 24206662

Gattu AK, Swenson ES, Iwakiri Y, Samuel VT, Troiano N, Berry R, Church CD, Rodeheffer MS, Carpenter TO, Chung C: Determination of mesenchymal stem cell fate by pigment epithelium-derived factor (PEDF) results in increased adiposity and reduced bone mineral content. FASEB J. 2013 Nov; 2013 Jul 25. PMID: 23887690

Spirli C, Locatelli L, Morell CM, Fiorotto R, Morton SD, Cadamuro M, Fabris L, Strazzabosco M: Protein kinase A-dependent pSer(675) -β-catenin, a novel signaling defect in a mouse model of congenital hepatic fibrosis. Hepatology. 2013 Nov; 2013 Sep 30. PMID: 23744610

Chovatiya R, Medzhitov R: Honor thy Go(na)ds. Immunol Cell Biol. 2013 Nov-Dec; 2013 Sep 24. PMID: 24060964

Kerrisk ME, Koleske AJ: Arg kinase signaling in dendrite and synapse stabilization pathways: memory, cocaine sensitivity, and stress. Int J Biochem Cell Biol. 2013 Nov; 2013 Aug 2. PMID: 23916785

Thakar J, Schmid S, Duke JL, García-Sastre A, Kleinstein SH: Overcoming NS1-mediated immune antagonism involves both interferon-dependent and independent mechanisms. J Interferon Cytokine Res. 2013 Nov; 2013 Jun 17. PMID: 23772952

Knauf F, Asplin JR, Granja I, Schmidt IM, Moeckel GW, David RJ, Flavell RA, Aronson PS: NALP3-mediated inflammation is a principal cause of progressive renal failure in oxalate nephropathy. Kidney Int. 2013 Nov; 2013 Jun 5. PMID: 23739234

Mark HH: The site of the optical image in the eye. Med Hypotheses. 2013 Nov; 2013 Aug 22. PMID: 24045093

Vuong BQ, Herrick-Reynolds K, Vaidyanathan B, Pucella JN, Ucher AJ, Donghia NM, Gu X, Nicolas L, Nowak U, Rahman N, Strout MP, Mills KD, Stavnezer J, Chaudhuri J: A DNA break- and phosphorylation-dependent positive feedback loop promotes immunoglobulin class-switch recombination. Nat Immunol. 2013 Nov; 2013 Oct 6. PMID: 24097111

Hurwitz M, Petrylak DP: Sequencing of agents for castration-resistant prostate cancer. Oncology (Williston Park). 2013 Nov. PMID: 24575543

Huang X, Deng XW: Organization of protein complexes under photomorphogenic UV-B in Arabidopsis. Plant Signal Behav. 2013 Nov; 2013 Dec 4. PMID: 24304604

Gao J, Ha BH, Lou HJ, Morse EM, Zhang R, Calderwood DA, Turk BE, Boggon TJ: Substrate and inhibitor specificity of the type II p21-activated kinase, PAK6. PLoS One. 2013; 2013 Oct 28. PMID: 24204982

Ilanges A, Jahanshahi M, Balobin DM, Pfleger CM: Alcohol interacts with genetic alteration of the Hippo tumor suppressor pathway to modulate tissue growth in Drosophila. PLoS One. 2013; 2013 Oct 21. PMID: 24205337

Licona-Limón P, Henao-Mejia J, Temann AU, Gagliani N, Licona-Limón I, Ishigame H, Hao L, Herbert DR, Flavell RA: Th9 Cells Drive Host Immunity against Gastrointestinal Worm Infection. Immunity. 2013 Oct 17. PMID: 24138883

Shin HM, Kapoor V, Guan T, Kaech SM, Welsh RM, Berg LJ: Epigenetic modifications induced by Blimp-1 Regulate CD8⁺ T cell memory progression during acute virus infection. Immunity. 2013 Oct 17; 2013 Oct 10. PMID: 24120360

Kumamoto Y, Linehan M, Weinstein JS, Laidlaw BJ, Craft JE, Iwasaki A: CD301b⁺ dermal dendritic cells drive T helper 2 cell-mediated immunity. Immunity. 2013 Oct 17; 2013 Sep 26. PMID: 24076051

Gao Y, Nish SA, Jiang R, Hou L, Licona-Limón P, Weinstein JS, Zhao H, Medzhitov R: Control of T helper 2 responses by transcription factor IRF4-dependent dendritic cells. Immunity. 2013 Oct 17; 2013 Sep 26. PMID: 24076050

Yang Y, Vasylyev DV, Dib-Hajj F, Veeramah KR, Hammer MF, Dib-Hajj SD, Waxman SG: Multistate structural modeling and voltage-clamp analysis of epilepsy/autism mutation Kv10.2-R327H demonstrate the role of this residue in stabilizing the channel closed state. J Neurosci. 2013 Oct 16. PMID: 24133262

Black JA, Waxman SG: Noncanonical roles of voltage-gated sodium channels. Neuron. 2013 Oct 16. PMID: 24139034

Wajapeyee N, Malonia SK, Palakurthy RK, Green MR: Oncogenic RAS directs silencing of tumor suppressor genes through ordered recruitment of transcriptional repressors. Genes Dev. 2013 Oct 15; 2013 Oct 8. PMID: 24105743

Inukai S, Slack F: MicroRNAs and the genetic network in aging. J Mol Biol. 2013 Oct 9; 2013 Jan 23. PMID: 23353823

Huang X, Ouyang X, Yang P, Lau OS, Chen L, Wei N, Deng XW: Conversion from CUL4-based COP1-SPA E3 apparatus to UVR8-COP1-SPA complexes underlies a distinct biochemical function of COP1 under UV-B. Proc Natl Acad Sci U S A. 2013 Oct 8; 2013 Sep 25. PMID: 24067658

Herazo-Maya JD, Noth I, Duncan SR, Kim S, Ma SF, Tseng GC, Feingold E, Juan-Guardela BM, Richards TJ, Lussier Y, Huang Y, Vij R, Lindell KO, Xue J, Gibson KF, Shapiro SD, Garcia JG, Kaminski N: Peripheral blood mononuclear cell gene expression profiles predict poor outcome in idiopathic pulmonary fibrosis. Sci Transl Med. 2013 Oct 2. PMID: 24089408

Song Y, Shen H, Du W, Goldstein DR: Inhibition of x-box binding protein 1 reduces tunicamycin-induced apoptosis in aged murine macrophages. Aging Cell. 2013 Oct; 2013 Jul 7. PMID: 23711292

Ross TD, Coon BG, Yun S, Baeyens N, Tanaka K, Ouyang M, Schwartz MA: Integrins in mechanotransduction. Curr Opin Cell Biol. 2013 Oct; 2013 Jun 21. PMID: 23797029

Eichmann A, Simons M: Need glucose to sprout: local metabolic control of angiogenesis. EMBO Mol Med. 2013 Oct; 2013 Aug 27. PMID: 23982994

Torrealday S, Lalioti MD, Guzeloglu-Kayisli O, Seli E: Characterization of the gonadotropin releasing hormone receptor (GnRHR) expression and activity in the female mouse ovary. Endocrinology. 2013 Oct; 2013 Aug 2. PMID: 23913446

Lozano E, Joller N, Cao Y, Kuchroo VK, Hafler DA: The CD226/CD155 interaction regulates the proinflammatory (Th1/Th17)/anti-inflammatory (Th2) balance in humans. J Immunol. 2013 Oct 1; 2013 Aug 26. PMID: 23980210

Yang Q, Zhang XF, Van Goor D, Dunn AP, Hyland C, Medeiros N, Forscher P: Protein kinase C activation decreases peripheral actin network density and increases central nonmuscle myosin II contractility in neuronal growth cones. Mol Biol Cell. 2013 Oct; 2013 Aug 21. PMID: 23966465

Liu RJ, Fuchikami M, Dwyer JM, Lepack AE, Duman RS, Aghajanian GK: GSK-3 inhibition potentiates the synaptogenic and antidepressant-like effects of subthreshold doses of ketamine. Neuropsychopharmacology. 2013 Oct; 2013 May 17. PMID: 23680942

Lewis AS, Picciotto MR: High-affinity nicotinic acetylcholine receptor expression and trafficking abnormalities in psychiatric illness. Psychopharmacology (Berl). 2013 Oct; 2013 Apr 28. PMID: 23624811

DiMaio D, Petti LM: The E5 proteins. Virology. 2013 Oct; 2013 May 31. PMID: 23731971

Ni TK, Landrette SF, Bjornson RD, Bosenberg MW, Xu T: Low-copy piggyBac transposon mutagenesis in mice identifies genes driving melanoma. Proc Natl Acad Sci U S A. 2013 Sep 17; 2013 Sep 3. PMID: 24003131

Querol L, Clark PL, Bailey MA, Cotsapas C, Cross AH, Hafler DA, Kleinstein SH, Lee JY, Yaari G, Willis SN, O'Connor KC: Protein array-based profiling of CSF identifies RBPJ as an autoantigen in multiple sclerosis. Neurology. 2013 Sep 10; 2013 Aug 6. PMID: 23921886

Li H, Fertuzinhos S, Mohns E, Hnasko TS, Verhage M, Edwards R, Sestan N, Crair MC: Laminar and columnar development of barrel cortex relies on thalamocortical neurotransmission. Neuron. 2013 Sep 4. PMID: 24012009

Um JW, Kaufman AC, Kostylev M, Heiss JK, Stagi M, Takahashi H, Kerrisk ME, Vortmeyer A, Wisniewski T, Koleske AJ, Gunther EC, Nygaard HB, Strittmatter SM: Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion protein. Neuron. 2013 Sep 4. PMID: 24012003

Tadeu AM, Horsley V: Notch signaling represses p63 expression in the developing surface ectoderm. Development. 2013 Sep; 2013 Aug 7. PMID: 23924630

Huang Y, Di Lorenzo A, Jiang W, Cantalupo A, Sessa WC, Giordano FJ: Hypoxia-inducible factor-1α in vascular smooth muscle regulates blood pressure homeostasis through a peroxisome proliferator-activated receptor-γ-angiotensin II receptor type 1 axis. Hypertension. 2013 Sep; 2013 Aug 5. PMID: 23918749

Elfenbein A, Simons M: Syndecan-4 signaling at a glance. J Cell Sci. 2013 Sep 1; 2013 Aug 22. PMID: 23970415

Todd TW, Lim J: Aggregation formation in the polyglutamine diseases: protection at a cost? Mol Cells. 2013 Sep; 2013 Jun 19. PMID: 23794019

He CH, Lee CG, Dela Cruz CS, Lee CM, Zhou Y, Ahangari F, Ma B, Herzog EL, Rosenberg SA, Li Y, Nour AM, Parikh CR, Schmidt I, Modis Y, Cantley L, Elias JA: Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor α2. Cell Rep. 2013 Aug 29; 2013 Aug 22. PMID: 23972995

Huang J, Yang Y, Zhao P, Gerrits MM, Hoeijmakers JG, Bekelaar K, Merkies IS, Faber CG, Dib-Hajj SD, Waxman SG: Small-fiber neuropathy Nav1.8 mutation shifts activation to hyperpolarized potentials and increases excitability of dorsal root ganglion neurons. J Neurosci. 2013 Aug 28. PMID: 23986244

Iyer SS, He Q, Janczy JR, Elliott EI, Zhong Z, Olivier AK, Sadler JJ, Knepper-Adrian V, Han R, Qiao L, Eisenbarth SC, Nauseef WM, Cassel SL, Sutterwala FS: Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation. Immunity. 2013 Aug 22; 2013 Aug 15. PMID: 23954133

Pang IK, Pillai PS, Iwasaki A: Efficient influenza A virus replication in the respiratory tract requires signals from TLR7 and RIG-I. Proc Natl Acad Sci U S A. 2013 Aug 20; 2013 Aug 5. PMID: 23918369

Huen SC, Moeckel GW, Cantley LG: Macrophage-specific deletion of transforming growth factor-β1 does not prevent renal fibrosis after severe ischemia-reperfusion or obstructive injury. Am J Physiol Renal Physiol. 2013 Aug 15; 2013 Jun 12. PMID: 23761668

Li M, Sun Y, Tomiya N, Hsu Y, Chai TC: Elevated polyamines in urothelial cells from OAB subjects mediate oxotremorine-evoked rapid intracellular calcium rise and delayed acetylcholine release. Am J Physiol Renal Physiol. 2013 Aug 15; 2013 May 22. PMID: 23698115

Sakurai T, Tsuchida M, Lampe PD, Murakami M: Cardiomyocyte FGF signaling is required for Cx43 phosphorylation and cardiac gap junction maintenance. Exp Cell Res. 2013 Aug 15; 2013 Jun 4. PMID: 23742896

Ivanov SV, Panaccione A, Brown B, Guo Y, Moskaluk CA, Wick MJ, Brown JL, Ivanova AV, Issaeva N, El-Naggar AK, Yarbrough WG: TrkC signaling is activated in adenoid cystic carcinoma and requires NT-3 to stimulate invasive behavior. Oncogene. 2013 Aug 8; 2012 Oct 1. PMID: 23027130

Bosurgi L, Bernink JH, Delgado Cuevas V, Gagliani N, Joannas L, Schmid ET, Booth CJ, Ghosh S, Rothlin CV: Paradoxical role of the proto-oncogene Axl and Mer receptor tyrosine kinases in colon cancer. Proc Natl Acad Sci U S A. 2013 Aug 6; 2013 Jul 22. PMID: 23878224

Zhang P, Huang B, Xu X, Sessa WC: Ten-eleven translocation (Tet) and thymine DNA glycosylase (TDG), components of the demethylation pathway, are direct targets of miRNA-29a. Biochem Biophys Res Commun. 2013 Aug 2; 2013 Jun 29. PMID: 23820384

Collaco AM, Jakab RL, Hoekstra NE, Mitchell KA, Brooks A, Ameen NA: Regulated traffic of anion transporters in mammalian Brunner's glands: a role for water and fluid transport. Am J Physiol Gastrointest Liver Physiol. 2013 Aug 1; 2013 Jun 6. PMID: 23744739

Rampias T, Pectasides E, Prasad M, Sasaki C, Gouveris P, Dimou A, Kountourakis P, Perisanidis C, Burtness B, Zaramboukas T, Rimm D, Fountzilas G, Psyrri A: Molecular profile of head and neck squamous cell carcinomas bearing p16 high phenotype. Ann Oncol. 2013 Aug; 2013 Feb 13. PMID: 23406730

Siragusa M, Sessa WC: Telmisartan exerts pleiotropic effects in endothelial cells and promotes endothelial cell quiescence and survival. Arterioscler Thromb Vasc Biol. 2013 Aug; 2013 May 23. PMID: 23702662

Zhang Y, Zhang X, Shan P, Hunt CR, Pandita TK, Lee PJ: A protective Hsp70-TLR4 pathway in lethal oxidant lung injury. J Immunol. 2013 Aug 1; 2013 Jul 1. PMID: 23817427

Koleske AJ: Molecular mechanisms of dendrite stability. Nat Rev Neurosci. 2013 Aug; 2013 Jul 10. PMID: 23839597

Fedeles S, Gallagher AR: Cell polarity and cystic kidney disease. Pediatr Nephrol. 2013 Aug; 2012 Nov 16. PMID: 23161205

Neugebauer NM, Einstein EB, Lopez MB, McClure-Begley TD, Mineur YS, Picciotto MR: Morphine dependence and withdrawal induced changes in cholinergic signaling. Pharmacol Biochem Behav. 2013 Aug; 2013 May 4. PMID: 23651795

Galbo T, Perry RJ, Jurczak MJ, Camporez JP, Alves TC, Kahn M, Guigni BA, Serr J, Zhang D, Bhanot S, Samuel VT, Shulman GI: Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signaling and ceramide synthesis in vivo. Proc Natl Acad Sci U S A. 2013 Jul 30; 2013 Jul 9. PMID: 23840067

Carrera Silva EA, Chan PY, Joannas L, Errasti AE, Gagliani N, Bosurgi L, Jabbour M, Perry A, Smith-Chakmakova F, Mucida D, Cheroutre H, Burstyn-Cohen T, Leighton JA, Lemke G, Ghosh S, Rothlin CV: T cell-derived protein S engages TAM receptor signaling in dendritic cells to control the magnitude of the immune response. Immunity. 2013 Jul 25; 2013 Jul 11. PMID: 23850380

Gourley SL, Olevska A, Gordon J, Taylor JR: Cytoskeletal determinants of stimulus-response habits. J Neurosci. 2013 Jul 17. PMID: 23864670

Sehgal K, Guo X, Koduru S, Shah A, Lin A, Yan X, Dhodapkar KM: Plasmacytoid dendritic cells, interferon signaling, and FcγR contribute to pathogenesis and therapeutic response in childhood immune thrombocytopenia. Sci Transl Med. 2013 Jul 10. PMID: 23843450

Vatner DF, Weismann D, Beddow SA, Kumashiro N, Erion DM, Liao XH, Grover GJ, Webb P, Phillips KJ, Weiss RE, Bogan JS, Baxter J, Shulman GI, Samuel VT: Thyroid hormone receptor-β agonists prevent hepatic steatosis in fat-fed rats but impair insulin sensitivity via discrete pathways. Am J Physiol Endocrinol Metab. 2013 Jul 1; 2013 May 7. PMID: 23651850

Svejda B, Kidd M, Timberlake A, Harry K, Kazberouk A, Schimmack S, Lawrence B, Pfragner R, Modlin IM: Serotonin and the 5-HT7 receptor: the link between hepatocytes, IGF-1 and small intestinal neuroendocrine tumors. Cancer Sci. 2013 Jul; 2013 May 24. PMID: 23578138

Boyer JL: Bile formation and secretion. Compr Physiol. 2013 Jul. PMID: 23897680

Soda K, Ishibe S: The function of endocytosis in podocytes. Curr Opin Nephrol Hypertens. 2013 Jul. PMID: 23703394

Zhang W, Hui KY, Gusev A, Warner N, Ng SM, Ferguson J, Choi M, Burberry A, Abraham C, Mayer L, Desnick RJ, Cardinale CJ, Hakonarson H, Waterman M, Chowers Y, Karban A, Brant SR, Silverberg MS, Gregersen PK, Katz S, Lifton RP, Zhao H, Nuñez G, Pe'er I, Peter I, Cho JH: Extended haplotype association study in Crohn's disease identifies a novel, Ashkenazi Jewish-specific missense mutation in the NF-κB pathway gene, HEATR3. Genes Immun. 2013 Jul-Aug; 2013 Apr 25. PMID: 23615072

Passamaneck YJ, Martindale MQ: Evidence for a phototransduction cascade in an early brachiopod embryo. Integr Comp Biol. 2013 Jul; 2013 Apr 29. PMID: 23630970

Monteiro A, Chen B, Ramos DM, Oliver JC, Tong X, Guo M, Wang WK, Fazzino L, Kamal F: Distal-less regulates eyespot patterns and melanization in Bicyclus butterflies. J Exp Zool B Mol Dev Evol. 2013 Jul; 2013 Apr 30. PMID: 23633220

Fiorotto R, Raizner A, Morell CM, Torsello B, Scirpo R, Fabris L, Spirli C, Strazzabosco M: Notch signaling regulates tubular morphogenesis during repair from biliary damage in mice. J Hepatol. 2013 Jul; 2013 Mar 7. PMID: 23500150

Li H, Alavian KN, Lazrove E, Mehta N, Jones A, Zhang P, Licznerski P, Graham M, Uo T, Guo J, Rahner C, Duman RS, Morrison RS, Jonas EA: A Bcl-xL-Drp1 complex regulates synaptic vesicle membrane dynamics during endocytosis. Nat Cell Biol. 2013 Jul; 2013 Jun 23. PMID: 23792689

Tworkoski KA, Platt JT, Bacchiocchi A, Bosenberg M, Boggon TJ, Stern DF: MERTK controls melanoma cell migration and survival and differentially regulates cell behavior relative to AXL. Pigment Cell Melanoma Res. 2013 Jul; 2013 May 21. PMID: 23617806

Li J, Yang L, Jin D, Nezames CD, Terzaghi W, Deng XW: UV-B-induced photomorphogenesis in Arabidopsis. Protein Cell. 2013 Jul; 2013 Jun 7. PMID: 23744340

Gleim S, Stitham J, Tang WH, Li H, Douville K, Chelikani P, Rade JJ, Martin KA, Hwa J: Human thromboxane A2 receptor genetic variants: in silico, in vitro and "in platelet" analysis. PLoS One. 2013; 2013 Jun 28. PMID: 23840660

Kang Y, Kim J, Anderson JP, Wu J, Gleim SR, Kundu RK, McLean DL, Kim JD, Park H, Jin SW, Hwa J, Quertermous T, Chun HJ: Apelin-APJ signaling is a critical regulator of endothelial MEF2 activation in cardiovascular development. Circ Res. 2013 Jun 21; 2013 Apr 19. PMID: 23603510

Ishigame H, Mosaheb MM, Sanjabi S, Flavell RA: Truncated form of TGF-βRII, but not its absence, induces memory CD8+ T cell expansion and lymphoproliferative disorder in mice. J Immunol. 2013 Jun 15; 2013 May 17. PMID: 23686479

Baumann AA, Benoit JB, Michalkova V, Mireji P, Attardo GM, Moulton JK, Wilson TG, Aksoy S: Juvenile hormone and insulin suppress lipolysis between periods of lactation during tsetse fly pregnancy. Mol Cell Endocrinol. 2013 Jun 15; 2013 Mar 14. PMID: 23499946

Wiseman SL, Shimizu Y, Palfrey C, Nairn AC: Proteasomal degradation of eukaryotic elongation factor-2 kinase (EF2K) is regulated by cAMP-PKA signaling and the SCFβTRCP ubiquitin E3 ligase. J Biol Chem. 2013 Jun 14; 2013 May 2. PMID: 23640883

Boyle LM: A neuroplasticity hypothesis of chronic stress in the basolateral amygdala. Yale J Biol Med. 2013 Jun; 2013 Jun 13. PMID: 23766733

Hu B, Elinav E, Huber S, Strowig T, Hao L, Hafemann A, Jin C, Wunderlich C, Wunderlich T, Eisenbarth SC, Flavell RA: Microbiota-induced activation of epithelial IL-6 signaling links inflammasome-driven inflammation with transmissible cancer. Proc Natl Acad Sci U S A. 2013 Jun 11; 2013 May 21. PMID: 23696660

Mulla MJ, Salmon JE, Chamley LW, Brosens JJ, Boeras CM, Kavathas PB, Abrahams VM: A role for uric acid and the Nalp3 inflammasome in antiphospholipid antibody-induced IL-1β production by human first trimester trophoblast. PLoS One. 2013; 2013 Jun 6. PMID: 23762324

Schroeder EA, Raimundo N, Shadel GS: Epigenetic silencing mediates mitochondria stress-induced longevity. Cell Metab. 2013 Jun 4. PMID: 23747251

Vanhouten JN, Wysolmerski JJ: The calcium-sensing receptor in the breast. Best Pract Res Clin Endocrinol Metab. 2013 Jun; 2013 Mar 28. PMID: 23856268

Yuan S, Zaidi S, Brueckner M: Congenital heart disease: emerging themes linking genetics and development. Curr Opin Genet Dev. 2013 Jun; 2013 Jun 20. PMID: 23790954

Wickham RJ, Solecki W, Rathbun LR, Neugebauer NM, Wightman RM, Addy NA: Advances in studying phasic dopamine signaling in brain reward mechanisms. Front Biosci (Elite Ed). 2013 Jun 1; 2013 Jun 1. PMID: 23747914

Boras-Granic K, Hamel PA: Wnt-signalling in the embryonic mammary gland. J Mammary Gland Biol Neoplasia. 2013 Jun; 2013 May 10. PMID: 23660702

Hines J, Gough JD, Corson TW, Crews CM: Posttranslational protein knockdown coupled to receptor tyrosine kinase activation with phosphoPROTACs. Proc Natl Acad Sci U S A. 2013 May 28; 2013 May 14. PMID: 23674677

Henao-Mejia J, Williams A, Goff LA, Staron M, Licona-Limón P, Kaech SM, Nakayama M, Rinn JL, Flavell RA: The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis. Immunity. 2013 May 23; 2013 Apr 25. PMID: 23623381

Gil-Henn H, Patsialou A, Wang Y, Warren MS, Condeelis JS, Koleske AJ: Arg/Abl2 promotes invasion and attenuates proliferation of breast cancer in vivo. Oncogene. 2013 May 23; 2012 Jul 9. PMID: 22777352

Yan D, Yamasaki M, Straub C, Watanabe M, Tomita S: Homeostatic control of synaptic transmission by distinct glutamate receptors. Neuron. 2013 May 22. PMID: 23719165

Zhang PX, Murray TS, Villella VR, Ferrari E, Esposito S, D'Souza A, Raia V, Maiuri L, Krause DS, Egan ME, Bruscia EM: Reduced caveolin-1 promotes hyperinflammation due to abnormal heme oxygenase-1 localization in lipopolysaccharide-challenged macrophages with dysfunctional cystic fibrosis transmembrane conductance regulator. J Immunol. 2013 May 15; 2013 Apr 19. PMID: 23606537

Yang Y, Estacion M, Dib-Hajj SD, Waxman SG: Molecular architecture of a sodium channel S6 helix: radial tuning of the voltage-gated sodium channel 1.7 activation gate. J Biol Chem. 2013 May 10; 2013 Mar 27. PMID: 23536180

Corti F, Finetti F, Ziche M, Simons M: The syndecan-4/protein kinase Cα pathway mediates prostaglandin E2-induced extracellular regulated kinase (ERK) activation in endothelial cells and angiogenesis in vivo. J Biol Chem. 2013 May 3; 2013 Mar 22. PMID: 23525101

Li W, Li Q, Qin L, Ali R, Qyang Y, Tassabehji M, Pober BR, Sessa WC, Giordano FJ, Tellides G: Rapamycin inhibits smooth muscle cell proliferation and obstructive arteriopathy attributable to elastin deficiency. Arterioscler Thromb Vasc Biol. 2013 May; 2013 Mar 14. PMID: 23493289

Leeman RF, Potenza MN: A targeted review of the neurobiology and genetics of behavioural addictions: an emerging area of research. Can J Psychiatry. 2013 May. PMID: 23756286

Thomas JL, Baker K, Han J, Calvo C, Nurmi H, Eichmann AC, Alitalo K: Interactions between VEGFR and Notch signaling pathways in endothelial and neural cells. Cell Mol Life Sci. 2013 May; 2013 Mar 12. PMID: 23479133

Gao L, Utsumi T, Tashiro K, Liu B, Zhang D, Swenson ES, Iwakiri Y: Reticulon 4B (Nogo-B) facilitates hepatocyte proliferation and liver regeneration in mice. Hepatology. 2013 May; 2013 Mar 19. PMID: 23299899

Shi H, Verma M, Zhang L, Dong C, Flavell RA, Bennett AM: Improved regenerative myogenesis and muscular dystrophy in mice lacking Mkp5. J Clin Invest. 2013 May; 2013 Apr 1. PMID: 23543058

Hoque R, Vodovotz Y, Mehal W: Therapeutic strategies in inflammasome mediated diseases of the liver. J Hepatol. 2013 May; 2012 Dec 21. PMID: 23266490

McGee HM, Schmidt BA, Booth CJ, Yancopoulos GD, Valenzuela DM, Murphy AJ, Stevens S, Flavell RA, Horsley V: IL-22 promotes fibroblast-mediated wound repair in the skin. J Invest Dermatol. 2013 May; 2012 Dec 6. PMID: 23223145

Paavola J, Schliffke S, Rossetti S, Kuo IY, Yuan S, Sun Z, Harris PC, Torres VE, Ehrlich BE: Polycystin-2 mutations lead to impaired calcium cycling in the heart and predispose to dilated cardiomyopathy. J Mol Cell Cardiol. 2013 May; 2013 Jan 30. PMID: 23376035

Choi C, Nitabach MN: Membrane-tethered ligands: tools for cell-autonomous pharmacological manipulation of biological circuits. Physiology (Bethesda). 2013 May. PMID: 23636262

Lanahan A, Zhang X, Fantin A, Zhuang Z, Rivera-Molina F, Speichinger K, Prahst C, Zhang J, Wang Y, Davis G, Toomre D, Ruhrberg C, Simons M: The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis. Dev Cell. 2013 Apr 29. PMID: 23639442

Kang H, Viollet B, Wu D: Genetic deletion of catalytic subunits of AMP-activated protein kinase increases osteoclasts and reduces bone mass in young adult mice. J Biol Chem. 2013 Apr 26; 2013 Mar 13. PMID: 23486478

Abdo B, Sliwa K, Schackert F, Bergeal N, Hatridge M, Frunzio L, Stone AD, Devoret M: Full coherent frequency conversion between two propagating microwave modes. Phys Rev Lett. 2013 Apr 26; 2013 Apr 26. PMID: 23679729

Dammen R, Haugen M, Svejda B, Alaimo D, Brenna O, Pfragner R, Gustafsson BI, Kidd M: The stimulatory adenosine receptor ADORA2B regulates serotonin (5-HT) synthesis and release in oxygen-depleted EC cells in inflammatory bowel disease. PLoS One. 2013; 2013 Apr 26. PMID: 23638125

Wang P, Yang L, Cheng G, Yang G, Xu Z, You F, Sun Q, Lin R, Fikrig E, Sutton RE: UBXN1 interferes with Rig-I-like receptor-mediated antiviral immune response by targeting MAVS. Cell Rep. 2013 Apr 25; 2013 Mar 28. PMID: 23545497

Kleinewietfeld M, Manzel A, Titze J, Kvakan H, Yosef N, Linker RA, Muller DN, Hafler DA: Sodium chloride drives autoimmune disease by the induction of pathogenic TH17 cells. Nature. 2013 Apr 25; 2013 Mar 6. PMID: 23467095

Ishigame H, Zenewicz LA, Sanjabi S, Licona-Limón P, Nakayama M, Leonard WJ, Flavell RA: Excessive Th1 responses due to the absence of TGF-β signaling cause autoimmune diabetes and dysregulated Treg cell homeostasis. Proc Natl Acad Sci U S A. 2013 Apr 23; 2013 Apr 8. PMID: 23569233

Huang Q, Qin L, Dai S, Zhang H, Pasula S, Zhou H, Chen H, Min W: AIP1 suppresses atherosclerosis by limiting hyperlipidemia-induced inflammation and vascular endothelial dysfunction. Arterioscler Thromb Vasc Biol. 2013 Apr; 2013 Feb 14. PMID: 23413429

Torii M, Hackett TA, Rakic P, Levitt P, Polley DB: EphA signaling impacts development of topographic connectivity in auditory corticofugal systems. Cereb Cortex. 2013 Apr; 2012 Apr 5. PMID: 22490549

Jaba IM, Zhuang ZW, Li N, Jiang Y, Martin KA, Sinusas AJ, Papademetris X, Simons M, Sessa WC, Young LH, Tirziu D: NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth. J Clin Invest. 2013 Apr. PMID: 23454748

Howe JR: CrossTalk proposal: TARPs modulate AMPA receptor gating transitions. J Physiol. 2013 Apr 1. PMID: 23547186

Zhang X, van den Pol AN: Direct inhibition of arcuate proopiomelanocortin neurons: a potential mechanism for the orexigenic actions of dynorphin. J Physiol. 2013 Apr 1; 2013 Jan 14. PMID: 23318874

Zattas D, Adle DJ, Rubenstein EM, Hochstrasser M: N-terminal acetylation of the yeast Derlin Der1 is essential for Hrd1 ubiquitin-ligase activity toward luminal ER substrates. Mol Biol Cell. 2013 Apr; 2013 Jan 30. PMID: 23363603

Deng X, Cao Y, Liu Y, Li F, Sambandam K, Rajaraman S, Perkins AS, Fields AP, Hellmich MR, Townsend CM Jr, Thompson EA, Ko TC: Overexpression of Evi-1 oncoprotein represses TGF-β signaling in colorectal cancer. Mol Carcinog. 2013 Apr; 2011 Dec 7. PMID: 22161860

English DP, Roque DM, Santin AD: HER2 expression beyond breast cancer: therapeutic implications for gynecologic malignancies. Mol Diagn Ther. 2013 Apr. PMID: 23529353

Chen L, Flies DB: Molecular mechanisms of T cell co-stimulation and co-inhibition. Nat Rev Immunol. 2013 Apr; 2013 Mar 8. PMID: 23470321

Teichmann LL, Schenten D, Medzhitov R, Kashgarian M, Shlomchik MJ: Signals via the adaptor MyD88 in B cells and DCs make distinct and synergistic contributions to immune activation and tissue damage in lupus. Immunity. 2013 Mar 21; 2013 Mar 14. PMID: 23499488

Mitra N, Liu Y, Liu J, Serebryany E, Mooney V, DeVree BT, Sunahara RK, Yan EC: Calcium-dependent ligand binding and G-protein signaling of family B GPCR parathyroid hormone 1 receptor purified in nanodiscs. ACS Chem Biol. 2013 Mar 15; 2013 Jan 30. PMID: 23237450

Song L, Santos-Sacchi J: Disparities in voltage-sensor charge and electromotility imply slow chloride-driven state transitions in the solute carrier SLC26a5. Proc Natl Acad Sci U S A. 2013 Mar 5; 2013 Feb 19. PMID: 23431177

Foss FM: Treatment strategies for peripheral T-cell lymphomas. Best Pract Res Clin Haematol. 2013 Mar; 2013 May 25. PMID: 23768640

Hoffman AE, Liu R, Fu A, Zheng T, Slack F, Zhu Y: Targetome profiling, pathway analysis and genetic association study implicate miR-202 in lymphomagenesis. Cancer Epidemiol Biomarkers Prev. 2013 Mar; 2013 Jan 18. PMID: 23334589

Berke IC, Li Y, Modis Y: Structural basis of innate immune recognition of viral RNA. Cell Microbiol. 2013 Mar; 2012 Nov 21. PMID: 23110455

Scholl UI, Lifton RP: New insights into aldosterone-producing adenomas and hereditary aldosteronism: mutations in the K+ channel KCNJ5. Curr Opin Nephrol Hypertens. 2013 Mar. PMID: 23318698

Schniederberend M, Abdurachim K, Murray TS, Kazmierczak BI: The GTPase activity of FlhF is dispensable for flagellar localization, but not motility, in Pseudomonas aeruginosa. J Bacteriol. 2013 Mar; 2012 Dec 21. PMID: 23264582

Deng Y, Atri D, Eichmann A, Simons M: Endothelial ERK signaling controls lymphatic fate specification. J Clin Invest. 2013 Mar; 2013 Feb 8. PMID: 23391722

Hedl M, Abraham C: Negative regulation of human mononuclear phagocyte function. Mucosal Immunol. 2013 Mar; 2013 Jan 23. PMID: 23340822

Pang IK, Ichinohe T, Iwasaki A: IL-1R signaling in dendritic cells replaces pattern-recognition receptors in promoting CD8⁺ T cell responses to influenza A virus. Nat Immunol. 2013 Mar; 2013 Jan 13. PMID: 23314004

Goldsmith TH: Evolutionary tinkering with visual photoreception. Vis Neurosci. 2013 Mar; 2012 Mar 6. PMID: 22391141

Mineur YS, Obayemi A, Wigestrand MB, Fote GM, Calarco CA, Li AM, Picciotto MR: Cholinergic signaling in the hippocampus regulates social stress resilience and anxiety- and depression-like behavior. Proc Natl Acad Sci U S A. 2013 Feb 26; 2013 Feb 11. PMID: 23401542

Hyder F, Rothman DL, Bennett MR: Cortical energy demands of signaling and nonsignaling components in brain are conserved across mammalian species and activity levels. Proc Natl Acad Sci U S A. 2013 Feb 26; 2013 Jan 14. PMID: 23319606

Liu W, Draheim KM, Zhang R, Calderwood DA, Boggon TJ: Mechanism for KRIT1 release of ICAP1-mediated suppression of integrin activation. Mol Cell. 2013 Feb 21; 2013 Jan 11. PMID: 23317506

Kim I, Pan W, Jones SA, Zhang Y, Zhuang X, Wu D: Clathrin and AP2 are required for PtdIns(4,5)P2-mediated formation of LRP6 signalosomes. J Cell Biol. 2013 Feb 18; 2013 Feb 11. PMID: 23400998

Torii M, Rakic P, Levitt P: Role of EphA/ephrin--a signaling in the development of topographic maps in mouse corticothalamic projections. J Comp Neurol. 2013 Feb 15. PMID: 22821544

Li MD, Ruan HB, Hughes ME, Lee JS, Singh JP, Jones SP, Nitabach MN, Yang X: O-GlcNAc signaling entrains the circadian clock by inhibiting BMAL1/CLOCK ubiquitination. Cell Metab. 2013 Feb 5. PMID: 23395176

Singh R, De Aguiar RB, Naik S, Mani S, Ostadsharif K, Wencker D, Sotoudeh M, Malekzadeh R, Sherwin RS, Mani A: LRP6 enhances glucose metabolism by promoting TCF7L2-dependent insulin receptor expression and IGF receptor stabilization in humans. Cell Metab. 2013 Feb 5. PMID: 23395167

Qian F, Bolen CR, Jing C, Wang X, Zheng W, Zhao H, Fikrig E, Bruce RD, Kleinstein SH, Montgomery RR: Impaired toll-like receptor 3-mediated immune responses from macrophages of patients chronically infected with hepatitis C virus. Clin Vaccine Immunol. 2013 Feb; 2012 Dec 5. PMID: 23220997

Lackner S, Schwendinger-Schreck J, Jülich D, Holley SA: Segmental assembly of fibronectin matrix requires rap1b and integrin α5. Dev Dyn. 2013 Feb; 2013 Jan 7. PMID: 23192979

Vonhoff F, Kuehn C, Blumenstock S, Sanyal S, Duch C: Temporal coherency between receptor expression, neural activity and AP-1-dependent transcription regulates Drosophila motoneuron dendrite development. Development. 2013 Feb 1. PMID: 23293292

Lawton AK, Nandi A, Stulberg MJ, Dray N, Sneddon MW, Pontius W, Emonet T, Holley SA: Regulated tissue fluidity steers zebrafish body elongation. Development. 2013 Feb 1. PMID: 23293289

Schmidt IM, Hall IE, Kale S, Lee S, He CH, Lee Y, Chupp GL, Moeckel GW, Lee CG, Elias JA, Parikh CR, Cantley LG: Chitinase-like protein Brp-39/YKL-40 modulates the renal response to ischemic injury and predicts delayed allograft function. J Am Soc Nephrol. 2013 Feb; 2013 Jan 4. PMID: 23291472

Schmitt CE, Woolls MJ, Jin SW: Mutant-specific gene expression profiling identifies SRY-related HMG box 11b (SOX11b) as a novel regulator of vascular development in zebrafish. Mol Cells. 2013 Feb; 2013 Feb 21. PMID: 23456338

Dai M, Xue Q, Mccray T, Margavage K, Chen F, Lee JH, Nezames CD, Guo L, Terzaghi W, Wan J, Deng XW, Wang H: The PP6 phosphatase regulates ABI5 phosphorylation and abscisic acid signaling in Arabidopsis. Plant Cell. 2013 Feb; 2013 Feb 12. PMID: 23404889

Lin YC, Yeckel MF, Koleske AJ: Abl2/Arg controls dendritic spine and dendrite arbor stability via distinct cytoskeletal control pathways. J Neurosci. 2013 Jan 30. PMID: 23365224

Nelson JC, Colón-Ramos DA: Serotonergic neurosecretory synapse targeting is controlled by netrin-releasing guidepost neurons in Caenorhabditis elegans. J Neurosci. 2013 Jan 23. PMID: 23345213

Wu M, Wu X, De Camilli P: Calcium oscillations-coupled conversion of actin travelling waves to standing oscillations. Proc Natl Acad Sci U S A. 2013 Jan 22; 2013 Jan 7. PMID: 23297209

Shanahan CA, Gaffney BL, Jones RA, Strobel SA: Identification of c-di-GMP derivatives resistant to an EAL domain phosphodiesterase. Biochemistry. 2013 Jan 15; 2013 Jan 3. PMID: 23256840

Zhou F, Rasmussen A, Lee S, Agaisse H: The UPD3 cytokine couples environmental challenge and intestinal stem cell division through modulation of JAK/STAT signaling in the stem cell microenvironment. Dev Biol. 2013 Jan 15; 2012 Oct 27. PMID: 23110761

Davis MJ, Ha BH, Holman EC, Halaban R, Schlessinger J, Boggon TJ: RAC1P29S is a spontaneously activating cancer-associated GTPase. Proc Natl Acad Sci U S A. 2013 Jan 15; 2013 Jan 2. PMID: 23284172

Mertz AF, Che Y, Banerjee S, Goldstein JM, Rosowski KA, Revilla SF, Niessen CM, Marchetti MC, Dufresne ER, Horsley V: Cadherin-based intercellular adhesions organize epithelial cell-matrix traction forces. Proc Natl Acad Sci U S A. 2013 Jan 15; 2012 Dec 31. PMID: 23277553

Collins KM, Koelle MR: Postsynaptic ERG potassium channels limit muscle excitability to allow distinct egg-laying behavior states in Caenorhabditis elegans. J Neurosci. 2013 Jan 9. PMID: 23303953

Townsend GE 2nd, Raghavan V, Zwir I, Groisman EA: Intramolecular arrangement of sensor and regulator overcomes relaxed specificity in hybrid two-component systems. Proc Natl Acad Sci U S A. 2013 Jan 8; 2012 Dec 19. PMID: 23256153

Groisman EA, Hollands K, Kriner MA, Lee EJ, Park SY, Pontes MH: Bacterial Mg2+ homeostasis, transport, and virulence. Annu Rev Genet. 2013; 2013 Sep 20. PMID: 24079267

Lawan A, Shi H, Gatzke F, Bennett AM: Diversity and specificity of the mitogen-activated protein kinase phosphatase-1 functions. Cell Mol Life Sci. 2013 Jan; 2012 Jun 14. PMID: 22695679

Duric V, Duman RS: Depression and treatment response: dynamic interplay of signaling pathways and altered neural processes. Cell Mol Life Sci. 2013 Jan; 2012 May 15. PMID: 22585060

Ju R, Simons M: Syndecan 4 regulation of PDK1-dependent Akt activation. Cell Signal. 2013 Jan; 2012 Sep 10. PMID: 22975683

Eichmann A, Thomas JL: Molecular parallels between neural and vascular development. Cold Spring Harb Perspect Med. 2013 Jan 1; 2013 Jan 1. PMID: 23024177

Amaya MJ, Nathanson MH: Calcium signaling in the liver. Compr Physiol. 2013 Jan. PMID: 23720295

Yordy B, Tal MC, Hayashi K, Arojo O, Iwasaki A: Autophagy and selective deployment of Atg proteins in antiviral defense. Int Immunol. 2013 Jan; 2012 Oct 5. PMID: 23042773

Bucala R: MIF, MIF alleles, and prospects for therapeutic intervention in autoimmunity. J Clin Immunol. 2013 Jan; 2012 Sep 12. PMID: 22968741

Guo L, Nezames CD, Sheng L, Deng X, Wei N: Cullin-RING ubiquitin ligase family in plant abiotic stress pathways(F). J Integr Plant Biol. 2013 Jan. PMID: 23206256

Humphrey JD: Possible mechanical roles of glycosaminoglycans in thoracic aortic dissection and associations with dysregulated transforming growth factor-β. J Vasc Res. 2013; 2012 Sep 25. PMID: 23018968

Uchil PD, Hinz A, Siegel S, Coenen-Stass A, Pertel T, Luban J, Mothes W: TRIM protein-mediated regulation of inflammatory and innate immune signaling and its association with antiretroviral activity. J Virol. 2013 Jan; 2012 Oct 17. PMID: 23077300

Mercan F, Lee H, Kolli S, Bennett AM: Novel role for SHP-2 in nutrient-responsive control of S6 kinase 1 signaling. Mol Cell Biol. 2013 Jan; 2012 Nov 5. PMID: 23129808

Ouyang X, Ghani A, Malik A, Wilder T, Colegio OR, Flavell RA, Cronstein BN, Mehal WZ: Adenosine is required for sustained inflammasome activation via the A₂A receptor and the HIF-1α pathway. Nat Commun. 2013. PMID: 24352507

Zhu Y, Yao S, Iliopoulou BP, Han X, Augustine MM, Xu H, Phennicie RT, Flies SJ, Broadwater M, Ruff W, Taube JM, Zheng L, Luo L, Zhu G, Chen J, Chen L: B7-H5 costimulates human T cells via CD28H. Nat Commun. 2013. PMID: 23784006

Kim J, Kang Y, Kojima Y, Lighthouse JK, Hu X, Aldred MA, McLean DL, Park H, Comhair SA, Greif DM, Erzurum SC, Chun HJ: An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension. Nat Med. 2013 Jan; 2012 Dec 23. PMID: 23263626

Dib-Hajj SD, Yang Y, Black JA, Waxman SG: The Na(V)1.7 sodium channel: from molecule to man. Nat Rev Neurosci. 2013 Jan; 2012 Dec 12. PMID: 23232607

Kidd M, Schimmack S, Lawrence B, Alaimo D, Modlin IM: EGFR/TGFα and TGFβ/CTGF Signaling in Neuroendocrine Neoplasia: Theoretical Therapeutic Targets. Neuroendocrinology. 2013; 2012 Jun 15. PMID: 22710195

Kopic S, Geibel JP: Gastric acid, calcium absorption, and their impact on bone health. Physiol Rev. 2013 Jan. PMID: 23303909

Dai M, Terzaghi W, Wang H: Multifaceted roles of Arabidopsis PP6 phosphatase in regulating cellular signaling and plant development. Plant Signal Behav. 2013 Jan; 2012 Oct 26. PMID: 23104112

Khurana E, Fu Y, Chen J, Gerstein M: Interpretation of genomic variants using a unified biological network approach. PLoS Comput Biol. 2013; 2013 Mar 7. PMID: 23505346

Shen H, Zhang W, Abraham C, Cho JH: Age and CD161 expression contribute to inter-individual variation in interleukin-23 response in CD8+ memory human T cells. PLoS One. 2013; 2013 Mar 1. PMID: 23469228

Rodriguez-Gil DJ, Hu W, Greer CA: Dishevelled proteins are associated with olfactory sensory neuron presynaptic terminals. PLoS One. 2013; 2013 Feb 20. PMID: 23437169

Hannemann S, Gao B, Galán JE: Salmonella modulation of host cell gene expression promotes its intracellular growth. PLoS Pathog. 2013; 2013 Oct 3. PMID: 24098123

Nour AM, Li Y, Wolenski J, Modis Y: Viral membrane fusion and nucleocapsid delivery into the cytoplasm are distinct events in some flaviviruses. PLoS Pathog. 2013; 2013 Sep 5. PMID: 24039574

Um JW, Strittmatter SM: Amyloid-β induced signaling by cellular prion protein and Fyn kinase in Alzheimer disease. Prion. 2013 Jan-Feb; 2012 Sep 17. PMID: 22987042

Luo D, Kohlway A, Pyle AM: Duplex RNA activated ATPases (DRAs): platforms for RNA sensing, signaling and processing. RNA Biol. 2013 Jan; 2012 Dec 10. PMID: 23228901

Chen PY, Qin L, Barnes C, Charisse K, Yi T, Zhang X, Ali R, Medina PP, Yu J, Slack FJ, Anderson DG, Kotelianski V, Wang F, Tellides G, Simons M: FGF regulates TGF-β signaling and endothelial-to-mesenchymal transition via control of let-7 miRNA expression. Cell Rep. 2012 Dec 27; 2012 Nov 29. PMID: 23200853

Yardley N, García-Castro MI: FGF signaling transforms non-neural ectoderm into neural crest. Dev Biol. 2012 Dec 15; 2012 Sep 19. PMID: 23000357

Shanahan CA, Strobel SA: The bacterial second messenger c-di-GMP: probing interactions with protein and RNA binding partners using cyclic dinucleotide analogs. Org Biomol Chem. 2012 Dec 14; 2012 Oct 29. PMID: 23108253

Cheadle L, Biederer T: The novel synaptogenic protein Farp1 links postsynaptic cytoskeletal dynamics and transsynaptic organization. J Cell Biol. 2012 Dec 10; 2012 Dec 3. PMID: 23209303

Zhou Y, Lee JY, Lee CM, Cho WK, Kang MJ, Koff JL, Yoon PO, Chae J, Park HO, Elias JA, Lee CG: Amphiregulin, an epidermal growth factor receptor ligand, plays an essential role in the pathogenesis of transforming growth factor-β-induced pulmonary fibrosis. J Biol Chem. 2012 Dec 7; 2012 Oct 19. PMID: 23086930

Zhou J, Wu Y, Lee SK, Fan R: High-content single-cell analysis on-chip using a laser microarray scanner. Lab Chip. 2012 Dec 7. PMID: 22991099

Su CY, Menuz K, Reisert J, Carlson JR: Non-synaptic inhibition between grouped neurons in an olfactory circuit. Nature. 2012 Dec 6; 2012 Nov 21. PMID: 23172146

Olausson P, Venkitaramani DV, Moran TD, Salter MW, Taylor JR, Lombroso PJ: The tyrosine phosphatase STEP constrains amygdala-dependent memory formation and neuroplasticity. Neuroscience. 2012 Dec 6; 2012 Aug 9. PMID: 22885232

Stahlhut C, Suárez Y, Lu J, Mishima Y, Giraldez AJ: miR-1 and miR-206 regulate angiogenesis by modulating VegfA expression in zebrafish. Development. 2012 Dec 1. PMID: 23132244

Varela L, Horvath TL: Leptin and insulin pathways in POMC and AgRP neurons that modulate energy balance and glucose homeostasis. EMBO Rep. 2012 Dec; 2012 Nov 13. PMID: 23146889

Hedl M, Abraham C: Nod2-induced autocrine interleukin-1 alters signaling by ERK and p38 to differentially regulate secretion of inflammatory cytokines. Gastroenterology. 2012 Dec; 2012 Sep 8. PMID: 22967725

Spirli C, Morell CM, Locatelli L, Okolicsanyi S, Ferrero C, Kim AK, Fabris L, Fiorotto R, Strazzabosco M: Cyclic AMP/PKA-dependent paradoxical activation of Raf/MEK/ERK signaling in polycystin-2 defective mice treated with sorafenib. Hepatology. 2012 Dec; 2012 Aug 27. PMID: 22653837

Zhou J, Niklason LE: Microfluidic artificial "vessels" for dynamic mechanical stimulation of mesenchymal stem cells. Integr Biol (Camb). 2012 Dec. PMID: 23114826

Wu Y, Garmire LX, Fan R: Inter-cellular signaling network reveals a mechanistic transition in tumor microenvironment. Integr Biol (Camb). 2012 Dec. PMID: 23080410

Pei B, Shin DG: Reconstruction of biological networks by incorporating prior knowledge into Bayesian network models. J Comput Biol. 2012 Dec. PMID: 23210479

Zhang XF, Hyland C, Van Goor D, Forscher P: Calcineurin-dependent cofilin activation and increased retrograde actin flow drive 5-HT-dependent neurite outgrowth in Aplysia bag cell neurons. Mol Biol Cell. 2012 Dec; 2012 Oct 24. PMID: 23097492

Hickey CM, Wilson NR, Hochstrasser M: Function and regulation of SUMO proteases. Nat Rev Mol Cell Biol. 2012 Dec. PMID: 23175280

Johnson MA, Lombroso PJ: A common STEP in the synaptic pathology of diverse neuropsychiatric disorders. Yale J Biol Med. 2012 Dec; 2012 Dec 13. PMID: 23239949

Haugen M, Dammen R, Svejda B, Gustafsson BI, Pfragner R, Modlin I, Kidd M: Differential signal pathway activation and 5-HT function: the role of gut enterochromaffin cells as oxygen sensors. Am J Physiol Gastrointest Liver Physiol. 2012 Nov 15; 2012 Aug 30. PMID: 22936271

Lacar B, Herman P, Platel JC, Kubera C, Hyder F, Bordey A: Neural progenitor cells regulate capillary blood flow in the postnatal subventricular zone. J Neurosci. 2012 Nov 14. PMID: 23152626

Berke IC, Yu X, Modis Y, Egelman EH: MDA5 assembles into a polar helical filament on dsRNA. Proc Natl Acad Sci U S A. 2012 Nov 6; 2012 Oct 22. PMID: 23090998

McLean DL, Kim J, Kang Y, Shi H, Atkins GB, Jain MK, Chun HJ: Apelin/APJ signaling is a critical regulator of statin effects in vascular endothelial cells--brief report. Arterioscler Thromb Vasc Biol. 2012 Nov; 2012 Sep 20. PMID: 22995518

Neumeister VM, Sullivan CA, Lindner R, Lezon-Geyda K, Li J, Zavada J, Martel M, Glazer PM, Tuck DP, Rimm DL, Harris L: Hypoxia-induced protein CAIX is associated with somatic loss of BRCA1 protein and pathway activity in triple negative breast cancer. Breast Cancer Res Treat. 2012 Nov; 2012 Sep 14. PMID: 22976806

Stuhlmiller TJ, García-Castro MI: Current perspectives of the signaling pathways directing neural crest induction. Cell Mol Life Sci. 2012 Nov; 2012 May 1. PMID: 22547091

Santamaria X, Massasa EE, Taylor HS: Migration of cells from experimental endometriosis to the uterine endometrium. Endocrinology. 2012 Nov; 2012 Sep 11. PMID: 22968642

Mo M, Erdelyi I, Szigeti-Buck K, Benbow JH, Ehrlich BE: Prevention of paclitaxel-induced peripheral neuropathy by lithium pretreatment. FASEB J. 2012 Nov; 2012 Aug 13. PMID: 22889832

Lee YJ, Jeschke GR, Roelants FM, Thorner J, Turk BE: Reciprocal phosphorylation of yeast glycerol-3-phosphate dehydrogenases in adaptation to distinct types of stress. Mol Cell Biol. 2012 Nov; 2012 Sep 17. PMID: 22988299

Kaech SM, Cui W: Transcriptional control of effector and memory CD8+ T cell differentiation. Nat Rev Immunol. 2012 Nov; 2012 Oct 19. PMID: 23080391

Murakami M, Sakurai T: Role of fibroblast growth factor signaling in vascular formation and maintenance: orchestrating signaling networks as an integrated system. Wiley Interdiscip Rev Syst Biol Med. 2012 Nov-Dec; 2012 Aug 28. PMID: 22930472

Anticevic A, Gancsos M, Murray JD, Repovs G, Driesen NR, Ennis DJ, Niciu MJ, Morgan PT, Surti TS, Bloch MH, Ramani R, Smith MA, Wang XJ, Krystal JH, Corlett PR: NMDA receptor function in large-scale anticorrelated neural systems with implications for cognition and schizophrenia. Proc Natl Acad Sci U S A. 2012 Oct 9; 2012 Sep 25. PMID: 23012427

Arnsten AF, Wang MJ, Paspalas CD: Neuromodulation of thought: flexibilities and vulnerabilities in prefrontal cortical network synapses. Neuron. 2012 Oct 4. PMID: 23040817

Picciotto MR, Higley MJ, Mineur YS: Acetylcholine as a neuromodulator: cholinergic signaling shapes nervous system function and behavior. Neuron. 2012 Oct 4. PMID: 23040810

Ha BH, Davis MJ, Chen C, Lou HJ, Gao J, Zhang R, Krauthammer M, Halaban R, Schlessinger J, Turk BE, Boggon TJ: Type II p21-activated kinases (PAKs) are regulated by an autoinhibitory pseudosubstrate. Proc Natl Acad Sci U S A. 2012 Oct 2; 2012 Sep 17. PMID: 22988085

Noblin DJ, Bertekap RL Jr, Burford NT, Hendricson A, Zhang L, Knox R, Banks M, O'Connell J, Alt A: Development of a high-throughput calcium flux assay for identification of all ligand types including positive, negative, and silent allosteric modulators for G protein-coupled receptors. Assay Drug Dev Technol. 2012 Oct; 2012 Jun 29. PMID: 22746835

Arias-Cartin R, Grimaldi S, Arnoux P, Guigliarelli B, Magalon A: Cardiolipin binding in bacterial respiratory complexes: structural and functional implications. Biochim Biophys Acta. 2012 Oct; 2012 Apr 17. PMID: 22561115

Psyrri A, Arkadopoulos N, Vassilakopoulou M, Smyrniotis V, Dimitriadis G: Pathways and targets in hepatocellular carcinoma. Expert Rev Anticancer Ther. 2012 Oct. PMID: 23176622

Liu L, Dai J, Zhao YO, Narasimhan S, Yang Y, Zhang L, Fikrig E: Ixodes scapularis JAK-STAT pathway regulates tick antimicrobial peptides, thereby controlling the agent of human granulocytic anaplasmosis. J Infect Dis. 2012 Oct; 2012 Aug 2. PMID: 22859824

Lau OS, Deng XW: The photomorphogenic repressors COP1 and DET1: 20 years later. Trends Plant Sci. 2012 Oct; 2012 Jun 15. PMID: 22705257

Sultana H, Neelakanta G, Foellmer HG, Montgomery RR, Anderson JF, Koski RA, Medzhitov RM, Fikrig E: Semaphorin 7A contributes to West Nile virus pathogenesis through TGF-β1/Smad6 signaling. J Immunol. 2012 Sep 15; 2012 Aug 15. PMID: 22896629

Geirsson A, Singh M, Ali R, Abbas H, Li W, Sanchez JA, Hashim S, Tellides G: Modulation of transforming growth factor-β signaling and extracellular matrix production in myxomatous mitral valves by angiotensin II receptor blockers. Circulation. 2012 Sep 11. PMID: 22965982

Greif DM, Kumar M, Lighthouse JK, Hum J, An A, Ding L, Red-Horse K, Espinoza FH, Olson L, Offermanns S, Krasnow MA: Radial construction of an arterial wall. Dev Cell. 2012 Sep 11. PMID: 22975322

Duman RS, Li N: A neurotrophic hypothesis of depression: role of synaptogenesis in the actions of NMDA receptor antagonists. Philos Trans R Soc Lond B Biol Sci. 2012 Sep 5. PMID: 22826346

Beech RD, Qu J, Leffert JJ, Lin A, Hong KA, Hansen J, Umlauf S, Mane S, Zhao H, Sinha R: Altered expression of cytokine signaling pathway genes in peripheral blood cells of alcohol dependent subjects: preliminary findings. Alcohol Clin Exp Res. 2012 Sep; 2012 Apr 4. PMID: 22471388

Krikun G, Trezza J, Shaw J, Rahman M, Guller S, Abrahams VM, Lockwood CJ: Lipopolysaccharide appears to activate human endometrial endothelial cells through TLR-4-dependent and TLR-4-independent mechanisms. Am J Reprod Immunol. 2012 Sep; 2012 Jun 4. PMID: 22672000

Ji W, Li Y, Wan T, Wang J, Zhang H, Chen H, Min W: Both internalization and AIP1 association are required for tumor necrosis factor receptor 2-mediated JNK signaling. Arterioscler Thromb Vasc Biol. 2012 Sep; 2012 Jun 28. PMID: 22743059

Saheki Y, De Camilli P: Synaptic vesicle endocytosis. Cold Spring Harb Perspect Biol. 2012 Sep 1; 2012 Sep 1. PMID: 22763746

Watanabe A, Sohail MA, Gautam S, Gomes DA, Mehal WZ: Adenine induces differentiation of rat hepatic stellate cells. Dig Dis Sci. 2012 Sep; 2012 May 10. PMID: 22573344

Chung RT, Stravitz RT, Fontana RJ, Schiodt FV, Mehal WZ, Reddy KR, Lee WM: Pathogenesis of liver injury in acute liver failure. Gastroenterology. 2012 Sep; 2012 Jul 13. PMID: 22796239

Lee CG, Herzog EL, Ahangari F, Zhou Y, Gulati M, Lee CM, Peng X, Feghali-Bostwick C, Jimenez SA, Varga J, Elias JA: Chitinase 1 is a biomarker for and therapeutic target in scleroderma-associated interstitial lung disease that augments TGF-β1 signaling. J Immunol. 2012 Sep 1; 2012 Jul 23. PMID: 22826322

Um JW, Nygaard HB, Heiss JK, Kostylev MA, Stagi M, Vortmeyer A, Wisniewski T, Gunther EC, Strittmatter SM: Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons. Nat Neurosci. 2012 Sep; 2012 Jul 22. PMID: 22820466

Fournier NM, Lee B, Banasr M, Elsayed M, Duman RS: Vascular endothelial growth factor regulates adult hippocampal cell proliferation through MEK/ERK- and PI3K/Akt-dependent signaling. Neuropharmacology. 2012 Sep; 2012 May 10. PMID: 22580375

Nezames CD, Deng XW: The COP9 signalosome: its regulation of cullin-based E3 ubiquitin ligases and role in photomorphogenesis. Plant Physiol. 2012 Sep; 2012 Jun 19. PMID: 22715109

Zaha VG, Young LH: AMP-activated protein kinase regulation and biological actions in the heart. Circ Res. 2012 Aug 31. PMID: 22935535

Choi C, Cao G, Tanenhaus AK, McCarthy EV, Jung M, Schleyer W, Shang Y, Rosbash M, Yin JC, Nitabach MN: Autoreceptor control of peptide/neurotransmitter corelease from PDF neurons determines allocation of circadian activity in drosophila. Cell Rep. 2012 Aug 30; 2012 Aug 2. PMID: 22938867

Idevall-Hagren O, Dickson EJ, Hille B, Toomre DK, De Camilli P: Optogenetic control of phosphoinositide metabolism. Proc Natl Acad Sci U S A. 2012 Aug 28; 2012 Jul 30. PMID: 22847441

Furukawa K, Gu H, Sudarsan N, Hayakawa Y, Hyodo M, Breaker RR: Identification of ligand analogues that control c-di-GMP riboswitches. ACS Chem Biol. 2012 Aug 17; 2012 Jun 19. PMID: 22646696

Christopher KJ, Wang B, Kong Y, Weatherbee SD: Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling. Dev Biol. 2012 Aug 15; 2012 Jun 12. PMID: 22698544

Kim JD, Kang H, Larrivée B, Lee MY, Mettlen M, Schmid SL, Roman BL, Qyang Y, Eichmann A, Jin SW: Context-dependent proangiogenic function of bone morphogenetic protein signaling is mediated by disabled homolog 2. Dev Cell. 2012 Aug 14. PMID: 22898784

Land BB, DiLeone RJ: Losing the lust for life: a new role for an old feeding Peptide? Neuron. 2012 Aug 9. PMID: 22884320

Goldstein J, Horsley V: Home sweet home: skin stem cell niches. Cell Mol Life Sci. 2012 Aug; 2012 Mar 13. PMID: 22410738

Kronengold J, Srinivas M, Verselis VK: The N-terminal half of the connexin protein contains the core elements of the pore and voltage gates. J Membr Biol. 2012 Aug; 2012 Jul 24. PMID: 22825713

Oron E, Ivanova N: Cell fate regulation in early mammalian development. Phys Biol. 2012 Aug; 2012 Aug 7. PMID: 22871593

Simons M: An inside view: VEGF receptor trafficking and signaling. Physiology (Bethesda). 2012 Aug. PMID: 22875452

Qu L, Li Y, Pan X, Zhang P, LaMotte RH, Ma C: Transient receptor potential canonical 3 (TRPC3) is required for IgG immune complex-induced excitation of the rat dorsal root ganglion neurons. J Neurosci. 2012 Jul 11. PMID: 22787041

Li X, Shan J, Chang W, Kim I, Bao J, Lee HJ, Zhang X, Samuel VT, Shulman GI, Liu D, Zheng JJ, Wu D: Chemical and genetic evidence for the involvement of Wnt antagonist Dickkopf2 in regulation of glucose metabolism. Proc Natl Acad Sci U S A. 2012 Jul 10; 2012 Jun 25. PMID: 22733757

Chandhoke SK, Mooseker MS: A role for myosin IXb, a motor-RhoGAP chimera, in epithelial wound healing and tight junction regulation. Mol Biol Cell. 2012 Jul; 2012 May 9. PMID: 22573889

Tufro A, Veron D: VEGF and podocytes in diabetic nephropathy. Semin Nephrol. 2012 Jul. PMID: 22958493

Li X, Zhang R, Draheim KM, Liu W, Calderwood DA, Boggon TJ: Structural basis for small G protein effector interaction of Ras-related protein 1 (Rap1) and adaptor protein Krev interaction trapped 1 (KRIT1). J Biol Chem. 2012 Jun 22; 2012 May 10. PMID: 22577140

Zhang F, Lazorchak AS, Liu D, Chen F, Su B: Inhibition of the mTORC2 and chaperone pathways to treat leukemia. Blood. 2012 Jun 21; 2012 May 7. PMID: 22566604

Roczniak-Ferguson A, Petit CS, Froehlich F, Qian S, Ky J, Angarola B, Walther TC, Ferguson SM: The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis. Sci Signal. 2012 Jun 12; 2012 Jun 12. PMID: 22692423

Gu H, Furukawa K, Breaker RR: Engineered allosteric ribozymes that sense the bacterial second messenger cyclic diguanosyl 5'-monophosphate. Anal Chem. 2012 Jun 5; 2012 May 21. PMID: 22519888

Khalil AM, Cambier JC, Shlomchik MJ: B cell receptor signal transduction in the GC is short-circuited by high phosphatase activity. Science. 2012 Jun 1; 2012 May 3. PMID: 22555432

Louvi A, Artavanis-Tsakonas S: Notch and disease: a growing field. Semin Cell Dev Biol. 2012 Jun; 2012 Feb 20. PMID: 22373641

Rivalta I, Sultan MM, Lee NS, Manley GA, Loria JP, Batista VS: Allosteric pathways in imidazole glycerol phosphate synthase. Proc Natl Acad Sci U S A. 2012 May 29; 2012 May 14. PMID: 22586084

Gan X, Wang J, Wang C, Sommer E, Kozasa T, Srinivasula S, Alessi D, Offermanns S, Simon MI, Wu D: PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12. Nat Cell Biol. 2012 May 20; 2012 May 20. PMID: 22609986

Ćelić AS, Petri ET, Benbow J, Hodsdon ME, Ehrlich BE, Boggon TJ: Calcium-induced conformational changes in C-terminal tail of polycystin-2 are necessary for channel gating. J Biol Chem. 2012 May 18; 2012 Apr 3. PMID: 22474326

Zhang H, Wang F, Kranzler HR, Anton RF, Gelernter J: Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses. Behav Brain Funct. 2012 May 16; 2012 May 16. PMID: 22591552

Hoque R, Sohail MA, Salhanick S, Malik AF, Ghani A, Robson SC, Mehal WZ: P2X7 receptor-mediated purinergic signaling promotes liver injury in acetaminophen hepatotoxicity in mice. Am J Physiol Gastrointest Liver Physiol. 2012 May 15; 2012 Mar 1. PMID: 22383490

Shi T, Bao J, Wang NX, Zheng J, Wu D: Identification Of Small Molecule TRABID Deubiquitinase Inhibitors By Computation-Based Virtual Screen. BMC Chem Biol. 2012 May 14; 2012 May 14. PMID: 22584113

Begum A, Kim Y, Lin Q, Yun Z: DLK1, delta-like 1 homolog (Drosophila), regulates tumor cell differentiation in vivo. Cancer Lett. 2012 May 1; 2011 Dec 3. PMID: 22142700

Dwyer JM, Lepack AE, Duman RS: mTOR activation is required for the antidepressant effects of mGluR₂/₃ blockade. Int J Neuropsychopharmacol. 2012 May; 2011 Nov 24. PMID: 22114864

Ali R, Huang Y, Maher SE, Kim RW, Giordano FJ, Tellides G, Geirsson A: miR-1 mediated suppression of Sorcin regulates myocardial contractility through modulation of Ca2+ signaling. J Mol Cell Cardiol. 2012 May; 2012 Feb 4. PMID: 22326846

Qian F, Montgomery RR: Quantitative imaging of lineage-specific Toll-like receptor-mediated signaling in monocytes and dendritic cells from small samples of human blood. J Vis Exp. 2012 Apr 16; 2012 Apr 16. PMID: 22525943

Lozano E, Dominguez-Villar M, Kuchroo V, Hafler DA: The TIGIT/CD226 axis regulates human T cell function. J Immunol. 2012 Apr 15; 2012 Mar 16. PMID: 22427644

Li MD, Ruan HB, Singh JP, Zhao L, Zhao T, Azarhoush S, Wu J, Evans RM, Yang X: O-GlcNAc transferase is involved in glucocorticoid receptor-mediated transrepression. J Biol Chem. 2012 Apr 13; 2012 Feb 27. PMID: 22371499

Berke IC, Modis Y: MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA. EMBO J. 2012 Apr 4; 2012 Feb 7. PMID: 22314235

Rivkees SA, Wendler CC: Regulation of cardiovascular development by adenosine and adenosine-mediated embryo protection. Arterioscler Thromb Vasc Biol. 2012 Apr. PMID: 22423036

Xue Q, Miller-Jensen K: Systems biology of virus-host signaling network interactions. BMB Rep. 2012 Apr. PMID: 22531130

Higley MJ, Sabatini BL: Calcium signaling in dendritic spines. Cold Spring Harb Perspect Biol. 2012 Apr 1; 2012 Apr 1. PMID: 22338091

Eichmann A, Simons M: VEGF signaling inside vascular endothelial cells and beyond. Curr Opin Cell Biol. 2012 Apr; 2012 Feb 25. PMID: 22366328

Black JA, Waxman SG: Sodium channels and microglial function. Exp Neurol. 2012 Apr; 2011 Oct 1. PMID: 21985863

Orr PT, Rubin AJ, Fan L, Kent BA, Frick KM: The progesterone-induced enhancement of object recognition memory consolidation involves activation of the extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin (mTOR) pathways in the dorsal hippocampus. Horm Behav. 2012 Apr; 2012 Jan 13. PMID: 22265866

Koo PJ, Morgensztern D, Boyer JL, Herbst RS: Targeting vascular endothelial growth factor in patients with squamous cell lung cancer. J Clin Oncol. 2012 Apr 1; 2012 Feb 21. PMID: 22355057

Hoque R, Malik AF, Gorelick F, Mehal WZ: Sterile inflammatory response in acute pancreatitis. Pancreas. 2012 Apr. PMID: 22415665

Sousa LP, Lax I, Shen H, Ferguson SM, De Camilli P, Schlessinger J: Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane. Proc Natl Acad Sci U S A. 2012 Mar 20; 2012 Feb 27. PMID: 22371560

Shi L, Shen QT, Kiel A, Wang J, Wang HW, Melia TJ, Rothman JE, Pincet F: SNARE proteins: one to fuse and three to keep the nascent fusion pore open. Science. 2012 Mar 16. PMID: 22422984

Larrivée B, Prahst C, Gordon E, del Toro R, Mathivet T, Duarte A, Simons M, Eichmann A: ALK1 signaling inhibits angiogenesis by cooperating with the Notch pathway. Dev Cell. 2012 Mar 13. PMID: 22421041

Samuel VT, Shulman GI: Mechanisms for insulin resistance: common threads and missing links. Cell. 2012 Mar 2. PMID: 22385956

Liu W, Singh R, Choi CS, Lee HY, Keramati AR, Samuel VT, Lifton RP, Shulman GI, Mani A: Low density lipoprotein (LDL) receptor-related protein 6 (LRP6) regulates body fat and glucose homeostasis by modulating nutrient sensing pathways and mitochondrial energy expenditure. J Biol Chem. 2012 Mar 2; 2012 Jan 9. PMID: 22232553

Bai JP, Surguchev A, Joshi P, Gross L, Navaratnam D: CDK5 interacts with Slo and affects its surface expression and kinetics through direct phosphorylation. Am J Physiol Cell Physiol. 2012 Mar 1; 2011 Nov 16. PMID: 22094329

Jones D, Li Y, He Y, Xu Z, Chen H, Min W: Mirtron microRNA-1236 inhibits VEGFR-3 signaling during inflammatory lymphangiogenesis. Arterioscler Thromb Vasc Biol. 2012 Mar; 2012 Jan 5. PMID: 22223733

Fernandez TV, Sanders SJ, Yurkiewicz IR, Ercan-Sencicek AG, Kim YS, Fishman DO, Raubeson MJ, Song Y, Yasuno K, Ho WS, Bilguvar K, Glessner J, Chu SH, Leckman JF, King RA, Gilbert DL, Heiman GA, Tischfield JA, Hoekstra PJ, Devlin B, Hakonarson H, Mane SM, Günel M, State MW: Rare copy number variants in tourette syndrome disrupt genes in histaminergic pathways and overlap with autism. Biol Psychiatry. 2012 Mar 1; 2011 Dec 14. PMID: 22169095

Ziai J, Hui P: BRAF mutation testing in clinical practice. Expert Rev Mol Diagn. 2012 Mar. PMID: 22369373

Spirli C, Locatelli L, Fiorotto R, Morell CM, Fabris L, Pozzan T, Strazzabosco M: Altered store operated calcium entry increases cyclic 3',5'-adenosine monophosphate production and extracellular signal-regulated kinases 1 and 2 phosphorylation in polycystin-2-defective cholangiocytes. Hepatology. 2012 Mar. PMID: 21987453

Jane-Wit D, Chun HJ: Mechanisms of dysfunction in senescent pulmonary endothelium. J Gerontol A Biol Sci Med Sci. 2012 Mar; 2012 Mar 5. PMID: 22396472

Go GW, Mani A: Low-density lipoprotein receptor (LDLR) family orchestrates cholesterol homeostasis. Yale J Biol Med. 2012 Mar; 2012 Mar 29. PMID: 22461740

Sneddon MW, Emonet T: Modeling cellular signaling: taking space into the computation. Nat Methods. 2012 Feb 28; 2012 Feb 28. PMID: 22373909

Jo H, Luo HR: Exploiting effectors of Rac GTPase. Chem Biol. 2012 Feb 24. PMID: 22365599

Warren MS, Bradley WD, Gourley SL, Lin YC, Simpson MA, Reichardt LF, Greer CA, Taylor JR, Koleske AJ: Integrin β1 signals through Arg to regulate postnatal dendritic arborization, synapse density, and behavior. J Neurosci. 2012 Feb 22. PMID: 22357865

Lou X, Fan F, Messa M, Raimondi A, Wu Y, Looger LL, Ferguson SM, De Camilli P: Reduced release probability prevents vesicle depletion and transmission failure at dynamin mutant synapses. Proc Natl Acad Sci U S A. 2012 Feb 21; 2012 Jan 30. PMID: 22308498

Raimundo N, Song L, Shutt TE, McKay SE, Cotney J, Guan MX, Gilliland TC, Hohuan D, Santos-Sacchi J, Shadel GS: Mitochondrial stress engages E2F1 apoptotic signaling to cause deafness. Cell. 2012 Feb 17. PMID: 22341444

Schwartz MA, Simons M: Lymphatics thrive on stress: mechanical force in lymphatic development. EMBO J. 2012 Feb 15; 2012 Feb 15. PMID: 22334045

Li Y, Berke IC, Modis Y: DNA binding to proteolytically activated TLR9 is sequence-independent and enhanced by DNA curvature. EMBO J. 2012 Feb 15; 2011 Dec 6. PMID: 22258621

Yeo WS, Zwir I, Huang HV, Shin D, Kato A, Groisman EA: Intrinsic negative feedback governs activation surge in two-component regulatory systems. Mol Cell. 2012 Feb 10. PMID: 22325356

Yuan S, Li J, Diener DR, Choma MA, Rosenbaum JL, Sun Z: Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation. Proc Natl Acad Sci U S A. 2012 Feb 7; 2012 Jan 23. PMID: 22308353

Qian F, Wang X, Zhang L, Chen S, Piecychna M, Allore H, Bockenstedt L, Malawista S, Bucala R, Shaw AC, Fikrig E, Montgomery RR: Age-associated elevation in TLR5 leads to increased inflammatory responses in the elderly. Aging Cell. 2012 Feb; 2011 Nov 28. PMID: 22023165

Chin A, Svejda B, Gustafsson BI, Granlund AB, Sandvik AK, Timberlake A, Sumpio B, Pfragner R, Modlin IM, Kidd M: The role of mechanical forces and adenosine in the regulation of intestinal enterochromaffin cell serotonin secretion. Am J Physiol Gastrointest Liver Physiol. 2012 Feb 1; 2011 Oct 28. PMID: 22038827

Voleti B, Duman RS: The roles of neurotrophic factor and Wnt signaling in depression. Clin Pharmacol Ther. 2012 Feb; 2011 Dec 28. PMID: 22205198

Bezbradica JS, Medzhitov R: Role of ITAM signaling module in signal integration. Curr Opin Immunol. 2012 Feb; 2012 Jan 11. PMID: 22240121

Jornayvaz FR, Lee HY, Jurczak MJ, Alves TC, Guebre-Egziabher F, Guigni BA, Zhang D, Samuel VT, Silva JE, Shulman GI: Thyroid hormone receptor-α gene knockout mice are protected from diet-induced hepatic insulin resistance. Endocrinology. 2012 Feb; 2011 Dec 6. PMID: 22147010

Masurkar AV, Chen WR: The influence of single bursts versus single spikes at excitatory dendrodendritic synapses. Eur J Neurosci. 2012 Feb; 2012 Jan 25. PMID: 22277089

Niciu MJ, Kelmendi B, Sanacora G: Overview of glutamatergic neurotransmission in the nervous system. Pharmacol Biochem Behav. 2012 Feb; 2011 Aug 26. PMID: 21889952

Wu Y, Lu Y, Chen W, Fu J, Fan R: In silico experimentation of glioma microenvironment development and anti-tumor therapy. PLoS Comput Biol. 2012 Feb; 2012 Feb 2. PMID: 22319429

Li J, Terzaghi W, Deng XW: Genomic basis for light control of plant development. Protein Cell. 2012 Feb; 2012 Mar 17. PMID: 22426979

Yu J, Thomson TC, Johnson J: Cross talk between estradiol and mTOR kinase in the regulation of ovarian granulosa proliferation. Reprod Sci. 2012 Feb. PMID: 22383759

Centrella M, McCarthy TL: Estrogen receptor dependent gene expression by osteoblasts - direct, indirect, circumspect, and speculative effects. Steroids. 2012 Feb; 2011 Nov 7. PMID: 22093482

El Bejjani R, Hammarlund M: Notch signaling inhibits axon regeneration. Neuron. 2012 Jan 26. PMID: 22284182

Jurczak MJ, Lee AH, Jornayvaz FR, Lee HY, Birkenfeld AL, Guigni BA, Kahn M, Samuel VT, Glimcher LH, Shulman GI: Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice. J Biol Chem. 2012 Jan 20; 2011 Nov 28. PMID: 22128176

Merrick D, Chapin H, Baggs JE, Yu Z, Somlo S, Sun Z, Hogenesch JB, Caplan MJ: The γ-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism. Dev Cell. 2012 Jan 17; 2011 Dec 15. PMID: 22178500

Sneddon MW, Pontius W, Emonet T: Stochastic coordination of multiple actuators reduces latency and improves chemotactic response in bacteria. Proc Natl Acad Sci U S A. 2012 Jan 17; 2011 Dec 27. PMID: 22203971

Wagner CS, Cresswell P: TLR and nucleotide-binding oligomerization domain-like receptor signals differentially regulate exogenous antigen presentation. J Immunol. 2012 Jan 15; 2011 Dec 9. PMID: 22156493

Sultana H, Neelakanta G, Rivero F, Blau-Wasser R, Schleicher M, Noegel AA: Ectopic expression of cyclase associated protein CAP restores the streaming and aggregation defects of adenylyl cyclase a deficient Dictyostelium discoideum cells. BMC Dev Biol. 2012 Jan 12; 2012 Jan 12. PMID: 22239817

Smith KD, Lipchock SV, Strobel SA: Structural and biochemical characterization of linear dinucleotide analogues bound to the c-di-GMP-I aptamer. Biochemistry. 2012 Jan 10; 2011 Dec 27. PMID: 22148472

Phillips ME, Sachdev RN, Willhite DC, Shepherd GM: Respiration drives network activity and modulates synaptic and circuit processing of lateral inhibition in the olfactory bulb. J Neurosci. 2012 Jan 4. PMID: 22219272

Dufour YS, Donohue TJ: Signal correlations in ecological niches can shape the organization and evolution of bacterial gene regulatory networks. Adv Microb Physiol. 2012. PMID: 23046950

Shahbazian D, Sznol J, Kluger HM: Vertical pathway targeting in cancer therapy. Adv Pharmacol. 2012. PMID: 22959021

Bogan JS: Regulation of glucose transporter translocation in health and diabetes. Annu Rev Biochem. 2012; 2012 Apr 5. PMID: 22482906

Razinia Z, Mäkelä T, Ylänne J, Calderwood DA: Filamins in mechanosensing and signaling. Annu Rev Biophys. 2012; 2012 Feb 23. PMID: 22404683

El Bejjani R, Hammarlund M: Neural regeneration in Caenorhabditis elegans. Annu Rev Genet. 2012; 2012 Sep 4. PMID: 22974301

Song Y, Shen H, Schenten D, Shan P, Lee PJ, Goldstein DR: Aging enhances the basal production of IL-6 and CCL2 in vascular smooth muscle cells. Arterioscler Thromb Vasc Biol. 2012 Jan; 2011 Oct 27. PMID: 22034510

Chen Z, Chen D, McCarthy TL, Centrella M, Zhang Y, Moeckel GW: Inorganic phosphate stimulates fibronectin expression in renal fibroblasts. Cell Physiol Biochem. 2012; 2012 Jun 18. PMID: 22759963

Alcalá AM, Flaherty KT: BRAF inhibitors for the treatment of metastatic melanoma: clinical trials and mechanisms of resistance. Clin Cancer Res. 2012 Jan 1. PMID: 22215904

Stuhlmiller TJ, García-Castro MI: FGF/MAPK signaling is required in the gastrula epiblast for avian neural crest induction. Development. 2012 Jan; 2011 Nov 30. PMID: 22129830

Smith-Vikos T, Slack FJ: MicroRNAs and their roles in aging. J Cell Sci. 2012 Jan 1. PMID: 22294612

Ma C, Nie H, Gu Q, Sikand P, Lamotte RH: In vivo responses of cutaneous C-mechanosensitive neurons in mouse to punctate chemical stimuli that elicit itch and nociceptive sensations in humans. J Neurophysiol. 2012 Jan; 2011 Oct 12. PMID: 21994268

Bouaouina M, Harburger DS, Calderwood DA: Talin and signaling through integrins. Methods Mol Biol. 2012. PMID: 21909921

Yang Y, Dib-Hajj SD, Zhang J, Zhang Y, Tyrrell L, Estacion M, Waxman SG: Structural modelling and mutant cycle analysis predict pharmacoresponsiveness of a Na(V)1.7 mutant channel. Nat Commun. 2012. PMID: 23149731

Hoshi N, Schenten D, Nish SA, Walther Z, Gagliani N, Flavell RA, Reizis B, Shen Z, Fox JG, Iwasaki A, Medzhitov R: MyD88 signalling in colonic mononuclear phagocytes drives colitis in IL-10-deficient mice. Nat Commun. 2012. PMID: 23047678

Duman RS, Li N, Liu RJ, Duric V, Aghajanian G: Signaling pathways underlying the rapid antidepressant actions of ketamine. Neuropharmacology. 2012 Jan; 2011 Sep 2. PMID: 21907221

Sanacora G, Treccani G, Popoli M: Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders. Neuropharmacology. 2012 Jan; 2011 Aug 3. PMID: 21827775

Kaczmarek LK: Gradients and modulation of K(+) channels optimize temporal accuracy in networks of auditory neurons. PLoS Comput Biol. 2012; 2012 Mar 15. PMID: 22438799

Anderson C, Zhou S, Sawin E, Horvitz HR, Hurwitz ME: SLI-1 Cbl inhibits the engulfment of apoptotic cells in C. elegans through a ligase-independent function. PLoS Genet. 2012; 2012 Dec 13. PMID: 23271977

Wang Y, Wong HC, Gullen EA, Lam W, Yang X, Shi Q, Lee KH, Cheng YC: Cryptopleurine analogs with modification of e ring exhibit different mechanism to rac-cryptopleurine and tylophorine. PLoS One. 2012; 2012 Dec 10. PMID: 23251437

Tong X, Lindemann A, Monteiro A: Differential involvement of Hedgehog signaling in butterfly wing and eyespot development. PLoS One. 2012; 2012 Dec 5. PMID: 23227236

Wang P, Bai F, Zenewicz LA, Dai J, Gate D, Cheng G, Yang L, Qian F, Yuan X, Montgomery RR, Flavell RA, Town T, Fikrig E: IL-22 signaling contributes to West Nile encephalitis pathogenesis. PLoS One. 2012; 2012 Aug 28. PMID: 22952908

Inukai S, de Lencastre A, Turner M, Slack F: Novel microRNAs differentially expressed during aging in the mouse brain. PLoS One. 2012; 2012 Jul 23. PMID: 22844398

Veron D, Villegas G, Aggarwal PK, Bertuccio C, Jimenez J, Velazquez H, Reidy K, Abrahamson DR, Moeckel G, Kashgarian M, Tufro A: Acute podocyte vascular endothelial growth factor (VEGF-A) knockdown disrupts alphaVbeta3 integrin signaling in the glomerulus. PLoS One. 2012; 2012 Jul 13. PMID: 22808199

Hatanaka K, Lanahan AA, Murakami M, Simons M: Fibroblast growth factor signaling potentiates VE-cadherin stability at adherens junctions by regulating SHP2. PLoS One. 2012; 2012 May 22. PMID: 22629427

Benavides VC, Mallela MK, Booth CJ, Wendler CC, Rivkees SA: Propylthiouracil is teratogenic in murine embryos. PLoS One. 2012; 2012 Apr 18. PMID: 22529993

Yu J, Zhang Y, Zhang X, Rudic RD, Bauer PM, Altieri DC, Sessa WC: Endothelium derived nitric oxide synthase negatively regulates the PDGF-survivin pathway during flow-dependent vascular remodeling. PLoS One. 2012; 2012 Feb 15. PMID: 22355372

Zito CR, Jilaveanu LB, Anagnostou V, Rimm D, Bepler G, Maira SM, Hackl W, Camp R, Kluger HM, Chao HH: Multi-level targeting of the phosphatidylinositol-3-kinase pathway in non-small cell lung cancer cells. PLoS One. 2012; 2012 Feb 15. PMID: 22355357

Diano S, Horvath TL: Mitochondrial uncoupling protein 2 (UCP2) in glucose and lipid metabolism. Trends Mol Med. 2012 Jan; 2011 Sep 12. PMID: 21917523

Duman RS, Voleti B: Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents. Trends Neurosci. 2012 Jan. PMID: 22217452

Ding M, Rzucidlo EM, Davey JC, Xie Y, Liu R, Jin Y, Stavola L, Martin KA: Adiponectin in the heart and vascular system. Vitam Horm. 2012. PMID: 23017720

Huang XA, Lin H: The microRNA regulation of stem cells. Wiley Interdiscip Rev Dev Biol. 2012 Jan-Feb; 2011 Nov 17. PMID: 23801669

Schmidt S, Mo M, Heidrich FM, Ćelić A, Ehrlich BE: C-terminal domain of chromogranin B regulates intracellular calcium signaling. J Biol Chem. 2011 Dec 30; 2011 Oct 20. PMID: 22016391

Li Z, Choo-Wing R, Sun H, Sureshbabu A, Sakurai R, Rehan VK, Bhandari V: A potential role of the JNK pathway in hyperoxia-induced cell death, myofibroblast transdifferentiation and TGF-β1-mediated injury in the developing murine lung. BMC Cell Biol. 2011 Dec 15; 2011 Dec 15. PMID: 22172122

Casale AE, McCormick DA: Active action potential propagation but not initiation in thalamic interneuron dendrites. J Neurosci. 2011 Dec 14. PMID: 22171033

Damsky WE, Curley DP, Santhanakrishnan M, Rosenbaum LE, Platt JT, Gould Rothberg BE, Taketo MM, Dankort D, Rimm DL, McMahon M, Bosenberg M: β-catenin signaling controls metastasis in Braf-activated Pten-deficient melanomas. Cancer Cell. 2011 Dec 13. PMID: 22172720

Tang W, Zhang Y, Xu W, Harden TK, Sondek J, Sun L, Li L, Wu D: A PLCβ/PI3Kγ-GSK3 signaling pathway regulates cofilin phosphatase slingshot2 and neutrophil polarization and chemotaxis. Dev Cell. 2011 Dec 13. PMID: 22172670

Alix E, Mukherjee S, Roy CR: Subversion of membrane transport pathways by vacuolar pathogens. J Cell Biol. 2011 Dec 12; 2011 Nov 28. PMID: 22123831

Meffre E: The establishment of early B cell tolerance in humans: lessons from primary immunodeficiency diseases. Ann N Y Acad Sci. 2011 Dec. PMID: 22236425

Lebastchi AH, Qin L, Khan SF, Zhou J, Geirsson A, Kim RW, Li W, Tellides G: Activation of human vascular cells decreases their expression of transforming growth factor-beta. Atherosclerosis. 2011 Dec; 2011 Aug 5. PMID: 21862019

Su B, Jacinto E: Mammalian TOR signaling to the AGC kinases. Crit Rev Biochem Mol Biol. 2011 Dec; 2011 Oct 10. PMID: 21981278

Christensen R, de la Torre-Ubieta L, Bonni A, Colón-Ramos DA: A conserved PTEN/FOXO pathway regulates neuronal morphology during C. elegans development. Development. 2011 Dec. PMID: 22069193

Lacar B, Young SZ, Platel JC, Bordey A: Gap junction-mediated calcium waves define communication networks among murine postnatal neural progenitor cells. Eur J Neurosci. 2011 Dec; 2011 Nov 18. PMID: 22098557

Fan N, Donnelly DF, LaMotte RH: Chronic compression of mouse dorsal root ganglion alters voltage-gated sodium and potassium currents in medium-sized dorsal root ganglion neurons. J Neurophysiol. 2011 Dec; 2011 Sep 14. PMID: 21917996

Lavoie EG, Wangdi T, Kazmierczak BI: Innate immune responses to Pseudomonas aeruginosa infection. Microbes Infect. 2011 Dec; 2011 Aug 2. PMID: 21839853

Thomas S: Project Prakash: Challenging the critical period: Association of Research in Vision and Ophthalmology National Meeting. Yale J Biol Med. 2011 Dec. PMID: 22180686

Chin JT, Troke JJ, Kimura N, Itoh S, Wang X, Palmer OP, Robbins RC, Fischbein MP: A novel cardioprotective agent in cardiac transplantation: metformin activation of AMP-activated protein kinase decreases acute ischemia-reperfusion injury and chronic rejection. Yale J Biol Med. 2011 Dec. PMID: 22180679

Flies DB, Sandler BJ, Sznol M, Chen L: Blockade of the B7-H1/PD-1 pathway for cancer immunotherapy. Yale J Biol Med. 2011 Dec. PMID: 22180678

Cui W, Liu Y, Weinstein JS, Craft J, Kaech SM: An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells. Immunity. 2011 Nov 23. PMID: 22118527

Bertuccio C, Veron D, Aggarwal PK, Holzman L, Tufro A: Vascular endothelial growth factor receptor 2 direct interaction with nephrin links VEGF-A signals to actin in kidney podocytes. J Biol Chem. 2011 Nov 18; 2011 Sep 21. PMID: 21937443

Rash BG, Grove EA: Shh and Gli3 regulate formation of the telencephalic-diencephalic junction and suppress an isthmus-like signaling source in the forebrain. Dev Biol. 2011 Nov 15; 2011 Sep 7. PMID: 21925158

Williams SA, Wilson JB, Clark AP, Mitson-Salazar A, Tomashevski A, Ananth S, Glazer PM, Semmes OJ, Bale AE, Jones NJ, Kupfer GM: Functional and physical interaction between the mismatch repair and FA-BRCA pathways. Hum Mol Genet. 2011 Nov 15; 2011 Aug 24. PMID: 21865299

MacLauchlan S, Yu J, Parrish M, Asoulin TA, Schleicher M, Krady MM, Zeng J, Huang PL, Sessa WC, Kyriakides TR: Endothelial nitric oxide synthase controls the expression of the angiogenesis inhibitor thrombospondin 2. Proc Natl Acad Sci U S A. 2011 Nov 15; 2011 Sep 26. PMID: 21949402

Kruglov EA, Gautam S, Guerra MT, Nathanson MH: Type 2 inositol 1,4,5-trisphosphate receptor modulates bile salt export pump activity in rat hepatocytes. Hepatology. 2011 Nov; 2011 Aug 30. PMID: 21748767

Tang WH, Stitham J, Gleim S, Di Febbo C, Porreca E, Fava C, Tacconelli S, Capone M, Evangelista V, Levantesi G, Wen L, Martin K, Minuz P, Rade J, Patrignani P, Hwa J: Glucose and collagen regulate human platelet activity through aldose reductase induction of thromboxane. J Clin Invest. 2011 Nov; 2011 Oct 17. PMID: 22005299

Kondo Y, Muto A, Kudo FA, Model L, Eghbalieh S, Chowdhary P, Dardik A: Age-related Notch-4 quiescence is associated with altered wall remodeling during vein graft adaptation. J Surg Res. 2011 Nov; 2011 Jul 19. PMID: 21872265

Kim KH, Toomre D, Bender JR: Splice isoform estrogen receptors as integral transmembrane proteins. Mol Biol Cell. 2011 Nov; 2011 Sep 21. PMID: 21937726

Sundberg TB, Darricarrere N, Cirone P, Li X, McDonald L, Mei X, Westlake CJ, Slusarski DC, Beynon RJ, Crews CM: Disruption of Wnt planar cell polarity signaling by aberrant accumulation of the MetAP-2 substrate Rab37. Chem Biol. 2011 Oct 28. PMID: 22035799

Cho JH, Gregersen PK: Genomics and the multifactorial nature of human autoimmune disease. N Engl J Med. 2011 Oct 27. PMID: 22029983

Rash BG, Lim HD, Breunig JJ, Vaccarino FM: FGF signaling expands embryonic cortical surface area by regulating Notch-dependent neurogenesis. J Neurosci. 2011 Oct 26. PMID: 22031906

Birkenfeld AL, Lee HY, Majumdar S, Jurczak MJ, Camporez JP, Jornayvaz FR, Frederick DW, Guigni B, Kahn M, Zhang D, Weismann D, Arafat AM, Pfeiffer AF, Lieske S, Oyadomari S, Ron D, Samuel VT, Shulman GI: Influence of the hepatic eukaryotic initiation factor 2alpha (eIF2alpha) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral glucose metabolism. J Biol Chem. 2011 Oct 21; 2011 Aug 5. PMID: 21832042

Sumioka A, Brown TE, Kato AS, Bredt DS, Kauer JA, Tomita S: PDZ binding of TARPγ-8 controls synaptic transmission but not synaptic plasticity. Nat Neurosci. 2011 Oct 16; 2011 Oct 16. PMID: 22002768

Luo D, Ding SC, Vela A, Kohlway A, Lindenbach BD, Pyle AM: Structural insights into RNA recognition by RIG-I. Cell. 2011 Oct 14. PMID: 22000018

Benbow JH, DeGray B, Ehrlich BE: Protection of neuronal calcium sensor 1 protein in cells treated with paclitaxel. J Biol Chem. 2011 Oct 7; 2011 Aug 1. PMID: 21808066

Shanahan CA, Gaffney BL, Jones RA, Strobel SA: Differential analogue binding by two classes of c-di-GMP riboswitches. J Am Chem Soc. 2011 Oct 5; 2011 Sep 8. PMID: 21838307

Takiar V, Caplan MJ: Polycystic kidney disease: pathogenesis and potential therapies. Biochim Biophys Acta. 2011 Oct; 2010 Dec 10. PMID: 21146605

Mitchell C, Provost K, Niu N, Homer R, Cohn L: IFN-γ acts on the airway epithelium to inhibit local and systemic pathology in allergic airway disease. J Immunol. 2011 Oct 1; 2011 Aug 26. PMID: 21873527

Xue Y, Lee S, Ha Y: Crystal structure of amyloid precursor-like protein 1 and heparin complex suggests a dual role of heparin in E2 dimerization. Proc Natl Acad Sci U S A. 2011 Sep 27; 2011 Sep 19. PMID: 21930949

Medzhitov R, Shevach EM, Trinchieri G, Mellor AL, Munn DH, Gordon S, Libby P, Hansson GK, Shortman K, Dong C, Gabrilovich D, Gabryšová L, Howes A, O'Garra A: Highlights of 10 years of immunology in Nature Reviews Immunology. Nat Rev Immunol. 2011 Sep 23; 2011 Sep 23. PMID: 21941295

Svejda B, Kidd M, Kazberouk A, Lawrence B, Pfragner R, Modlin IM: Limitations in small intestinal neuroendocrine tumor therapy by mTor kinase inhibition reflect growth factor-mediated PI3K feedback loop activation via ERK1/2 and AKT. Cancer. 2011 Sep 15; 2011 Mar 8. PMID: 21387274

Rudnick G: Cytoplasmic permeation pathway of neurotransmitter transporters. Biochemistry. 2011 Sep 6; 2011 Aug 10. PMID: 21774491

Wang F, Deng XW: Plant ubiquitin-proteasome pathway and its role in gibberellin signaling. Cell Res. 2011 Sep; 2011 Jul 26. PMID: 21788985

Zhong W: Golgi during development. Cold Spring Harb Perspect Biol. 2011 Sep 1; 2011 Sep 1. PMID: 21768608

Saxe JP, Lin H: Small noncoding RNAs in the germline. Cold Spring Harb Perspect Biol. 2011 Sep 1; 2011 Sep 1. PMID: 21669983

Ni N, Guo S, Langer P: Current concepts in the management of periocular infantile (capillary) hemangioma. Curr Opin Ophthalmol. 2011 Sep. PMID: 21730838

Brown MR, Kaczmarek LK: Potassium channel modulation and auditory processing. Hear Res. 2011 Sep; 2011 Mar 21. PMID: 21414395

Tal MC, Iwasaki A: Mitoxosome: a mitochondrial platform for cross-talk between cellular stress and antiviral signaling. Immunol Rev. 2011 Sep. PMID: 21884179

Li N, He X, Zhang Y, Qi X, Li H, Zhu X, He S: Brain-derived neurotrophic factor signalling mediates antidepressant effects of lamotrigine. Int J Neuropsychopharmacol. 2011 Sep; 2010 Sep 16. PMID: 20846461

Andrade V, Guerra M, Jardim C, Melo F, Silva W, Ortega JM, Robert M, Nathanson MH, Leite F: Nucleoplasmic calcium regulates cell proliferation through legumain. J Hepatol. 2011 Sep; 2011 Jan 13. PMID: 21237226

Pincus Z, Smith-Vikos T, Slack FJ: MicroRNA predictors of longevity in Caenorhabditis elegans. PLoS Genet. 2011 Sep; 2011 Sep 29. PMID: 21980307

Glazer PM, Le QT, Bristow R, Helleday T, Pelroy R, Bernhard EJ: New translational possibilities for microenvironmental modulation of radiosensitivity. Radiat Res. 2011 Sep; 2011 Jul 8. PMID: 21867431

Xue Y, Lee S, Wang Y, Ha Y: Crystal structure of the E2 domain of amyloid precursor protein-like protein 1 in complex with sucrose octasulfate. J Biol Chem. 2011 Aug 26; 2011 Jun 29. PMID: 21715329

Hofler C, Koelle MR: AGS-3 alters Caenorhabditis elegans behavior after food deprivation via RIC-8 activation of the neural G protein G αo. J Neurosci. 2011 Aug 10. PMID: 21832186

Carey AF, Carlson JR: Insect olfaction from model systems to disease control. Proc Natl Acad Sci U S A. 2011 Aug 9; 2011 Jul 11. PMID: 21746926

Yu L, Qin L, Zhang H, He Y, Chen H, Pober JS, Tellides G, Min W: AIP1 prevents graft arteriosclerosis by inhibiting interferon-γ-dependent smooth muscle cell proliferation and intimal expansion. Circ Res. 2011 Aug 5; 2011 Jun 23. PMID: 21700930

Liu J, Liu MY, Nguyen JB, Bhagat A, Mooney V, Yan EC: Thermal properties of rhodopsin: insight into the molecular mechanism of dim-light vision. J Biol Chem. 2011 Aug 5; 2011 Jun 9. PMID: 21659526

Shulman GI, Helfand SL: Indy knockdown in mice mimics elements of dietary restriction. Aging (Albany NY). 2011 Aug. PMID: 21937764

Li M, Wu ZM, Yang H, Huang SJ: NFκB and JNK/MAPK activation mediates the production of major macrophage- or dendritic cell-recruiting chemokine in human first trimester decidual cells in response to proinflammatory stimuli. J Clin Endocrinol Metab. 2011 Aug; 2011 Jun 15. PMID: 21677045

Rochier A, Nixon A, Yamashita N, Abe R, Abe R, Madri JA, Sumpio BE: Laminar shear, but not orbital shear, has a synergistic effect with thrombin stimulation on tissue factor expression in human umbilical vein endothelial cells. J Vasc Surg. 2011 Aug; 2011 Mar 2. PMID: 21367569

Alvero AB, Montagna MK, Holmberg JC, Craveiro V, Brown D, Mor G: Targeting the mitochondria activates two independent cell death pathways in ovarian cancer stem cells. Mol Cancer Ther. 2011 Aug; 2011 Jun 15. PMID: 21677151

Round JE, Sun H: The adaptor protein Nck2 mediates Slit1-induced changes in cortical neuron morphology. Mol Cell Neurosci. 2011 Aug; 2011 May 6. PMID: 21600986

Iwakiri Y: S-nitrosylation of proteins: a new insight into endothelial cell function regulated by eNOS-derived NO. Nitric Oxide. 2011 Aug 1; 2011 Apr 30. PMID: 21554971

Rivetta A, Kuroda T, Slayman C: Anion currents in yeast K+ transporters (TRK) characterize a structural homologue of ligand-gated ion channels. Pflugers Arch. 2011 Aug; 2011 May 10. PMID: 21556692

Hedl M, Abraham C: Distinct roles for Nod2 protein and autocrine interleukin-1beta in muramyl dipeptide-induced mitogen-activated protein kinase activation and cytokine secretion in human macrophages. J Biol Chem. 2011 Jul 29; 2011 Jun 9. PMID: 21659536

Wang M, Gamo NJ, Yang Y, Jin LE, Wang XJ, Laubach M, Mazer JA, Lee D, Arnsten AF: Neuronal basis of age-related working memory decline. Nature. 2011 Jul 27; 2011 Jul 27. PMID: 21796118

Shaw AC, Panda A, Joshi SR, Qian F, Allore HG, Montgomery RR: Dysregulation of human Toll-like receptor function in aging. Ageing Res Rev. 2011 Jul; 2010 Nov 10. PMID: 21074638

Chefetz I, Holmberg JC, Alvero AB, Visintin I, Mor G: Inhibition of Aurora-A kinase induces cell cycle arrest in epithelial ovarian cancer stem cells by affecting NFĸB pathway. Cell Cycle. 2011 Jul 1; 2011 Jul 1. PMID: 21623171

Hoque R, Sohail M, Malik A, Sarwar S, Luo Y, Shah A, Barrat F, Flavell R, Gorelick F, Husain S, Mehal W: TLR9 and the NLRP3 inflammasome link acinar cell death with inflammation in acute pancreatitis. Gastroenterology. 2011 Jul; 2011 Mar 24. PMID: 21439959

Murakami M, Nguyen LT, Hatanaka K, Schachterle W, Chen PY, Zhuang ZW, Black BL, Simons M: FGF-dependent regulation of VEGF receptor 2 expression in mice. J Clin Invest. 2011 Jul. PMID: 21633168

El-Hassar L, Hagenston AM, D'Angelo LB, Yeckel MF: Metabotropic glutamate receptors regulate hippocampal CA1 pyramidal neuron excitability via Ca²⁺ wave-dependent activation of SK and TRPC channels. J Physiol. 2011 Jul 1; 2011 May 16. PMID: 21576272

Donnelly DF, Kim I, Yang D, Carroll JL: Role of MaxiK-type calcium dependent K+ channels in rat carotid body hypoxia transduction during postnatal development. Respir Physiol Neurobiol. 2011 Jun 30; 2011 Feb 25. PMID: 21356332

Arnsten AF: Catecholamine influences on dorsolateral prefrontal cortical networks. Biol Psychiatry. 2011 Jun 15; 2011 Apr 13. PMID: 21489408

Mijares LA, Wangdi T, Sokol C, Homer R, Medzhitov R, Kazmierczak BI: Airway epithelial MyD88 restores control of Pseudomonas aeruginosa murine infection via an IL-1-dependent pathway. J Immunol. 2011 Jun 15; 2011 May 13. PMID: 21572023

Rabbani P, Takeo M, Chou W, Myung P, Bosenberg M, Chin L, Taketo MM, Ito M: Coordinated activation of Wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration. Cell. 2011 Jun 10. PMID: 21663796

Sarin R, Wu X, Abraham C: Inflammatory disease protective R381Q IL23 receptor polymorphism results in decreased primary CD4+ and CD8+ human T-cell functional responses. Proc Natl Acad Sci U S A. 2011 Jun 7; 2011 May 23. PMID: 21606346

D'Souza AD, Parish IA, McKay SE, Kaech SM, Shadel GS: Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling. Am J Pathol. 2011 Jun. PMID: 21641396

Matsuura H, Hartl D, Kang MJ, Dela Cruz CS, Koller B, Chupp GL, Homer RJ, Zhou Y, Cho WK, Elias JA, Lee CG: Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema. Am J Respir Cell Mol Biol. 2011 Jun; 2010 Jul 23. PMID: 20656949

Gamo NJ, Arnsten AF: Molecular modulation of prefrontal cortex: rational development of treatments for psychiatric disorders. Behav Neurosci. 2011 Jun. PMID: 21480691

Schulze C, McGowan M, Jordt SE, Ehrlich BE: Prolonged oxaliplatin exposure alters intracellular calcium signaling: a new mechanism to explain oxaliplatin-associated peripheral neuropathy. Clin Colorectal Cancer. 2011 Jun; 2011 Apr 22. PMID: 21859566

Venkitaramani DV, Moura PJ, Picciotto MR, Lombroso PJ: Striatal-enriched protein tyrosine phosphatase (STEP) knockout mice have enhanced hippocampal memory. Eur J Neurosci. 2011 Jun; 2011 Apr 19. PMID: 21501258

Strazzabosco M, Somlo S: Polycystic liver diseases: congenital disorders of cholangiocyte signaling. Gastroenterology. 2011 Jun; 2011 Apr 22. PMID: 21515270

McCarthy EV, Wu Y, Decarvalho T, Brandt C, Cao G, Nitabach MN: Synchronized bilateral synaptic inputs to Drosophila melanogaster neuropeptidergic rest/arousal neurons. J Neurosci. 2011 Jun 1. PMID: 21632940

Esemuede N, Lee T, Maier KG, Sumpio BE, Gahtan V: Lovastatin inhibits thrombospondin-1-induced smooth muscle cell chemotaxis. J Surg Res. 2011 Jun 1; 2009 Dec 18. PMID: 20338582

Wilson KA, Colavito SA, Schulz V, Wakefield PH, Sessa W, Tuck D, Stern DF: NFBD1/MDC1 regulates Cav1 and Cav2 independently of DNA damage and p53. Mol Cancer Res. 2011 Jun; 2011 May 6. PMID: 21551225

Tworkoski K, Singhal G, Szpakowski S, Zito CI, Bacchiocchi A, Muthusamy V, Bosenberg M, Krauthammer M, Halaban R, Stern DF: Phosphoproteomic screen identifies potential therapeutic targets in melanoma. Mol Cancer Res. 2011 Jun; 2011 Apr 26. PMID: 21521745

West AP, Shadel GS, Ghosh S: Mitochondria in innate immune responses. Nat Rev Immunol. 2011 Jun; 2011 May 20. PMID: 21597473

Quint C, Kondo Y, Manson RJ, Lawson JH, Dardik A, Niklason LE: Decellularized tissue-engineered blood vessel as an arterial conduit. Proc Natl Acad Sci U S A. 2011 May 31; 2011 May 12. PMID: 21571635

Overton JD, Leibel RL: Mahoganoid and mahogany mutations rectify the obesity of the yellow mouse by effects on endosomal traffic of MC4R protein. J Biol Chem. 2011 May 27; 2011 Apr 1. PMID: 21460229

Hedhli N, Huang Q, Kalinowski A, Palmeri M, Hu X, Russell RR, Russell KS: Endothelium-derived neuregulin protects the heart against ischemic injury. Circulation. 2011 May 24; 2011 May 9. PMID: 21555713

Wang X, Zhang F, Chen F, Liu D, Zheng Y, Zhang Y, Dong C, Su B: MEKK3 regulates IFN-gamma production in T cells through the Rac1/2-dependent MAPK cascades. J Immunol. 2011 May 15; 2011 Apr 6. PMID: 21471448

Qian F, Wang X, Zhang L, Lin A, Zhao H, Fikrig E, Montgomery RR: Impaired interferon signaling in dendritic cells from older donors infected in vitro with West Nile virus. J Infect Dis. 2011 May 15; 2011 Mar 11. PMID: 21398396

Ahn HS, Black JA, Zhao P, Tyrrell L, Waxman SG, Dib-Hajj SD: Nav1.7 is the predominant sodium channel in rodent olfactory sensory neurons. Mol Pain. 2011 May 10; 2011 May 10. PMID: 21569247

Smith KD, Shanahan CA, Moore EL, Simon AC, Strobel SA: Structural basis of differential ligand recognition by two classes of bis-(3'-5')-cyclic dimeric guanosine monophosphate-binding riboswitches. Proc Natl Acad Sci U S A. 2011 May 10; 2011 Apr 25. PMID: 21518891

Sweet RA, Ols ML, Cullen JL, Milam AV, Yagita H, Shlomchik MJ: Facultative role for T cells in extrafollicular Toll-like receptor-dependent autoreactive B-cell responses in vivo. Proc Natl Acad Sci U S A. 2011 May 10; 2011 Apr 25. PMID: 21518858

Bimboese P, Gibson CJ, Schmidt S, Xiang W, Ehrlich BE: Isoform-specific regulation of the inositol 1,4,5-trisphosphate receptor by O-linked glycosylation. J Biol Chem. 2011 May 6; 2011 Mar 7. PMID: 21383013

Li Q, Michaud M, Canosa S, Kuo A, Madri JA: GSK-3β: a signaling pathway node modulating neural stem cell and endothelial cell interactions. Angiogenesis. 2011 May; 2011 Jan 21. PMID: 21253820

Abraham C, Medzhitov R: Interactions between the host innate immune system and microbes in inflammatory bowel disease. Gastroenterology. 2011 May. PMID: 21530739

Arnsten AF: Prefrontal cortical network connections: key site of vulnerability in stress and schizophrenia. Int J Dev Neurosci. 2011 May; 2011 Feb 21. PMID: 21345366

Li G, Siddiqui H, Teng Y, Lin R, Wan XY, Li J, Lau OS, Ouyang X, Dai M, Wan J, Devlin PF, Deng XW, Wang H: Coordinated transcriptional regulation underlying the circadian clock in Arabidopsis. Nat Cell Biol. 2011 May; 2011 Apr 17. PMID: 21499259

Rathinam C, Matesic LE, Flavell RA: The E3 ligase Itch is a negative regulator of the homeostasis and function of hematopoietic stem cells. Nat Immunol. 2011 May; 2011 Apr 10. PMID: 21478879

Mehal WZ, Iredale J, Friedman SL: Scraping fibrosis: expressway to the core of fibrosis. Nat Med. 2011 May. PMID: 21546973

West AP, Brodsky IE, Rahner C, Woo DK, Erdjument-Bromage H, Tempst P, Walsh MC, Choi Y, Shadel GS, Ghosh S: TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature. 2011 Apr 28. PMID: 21525932

Huber S, Gagliani N, Esplugues E, O'Connor W Jr, Huber FJ, Chaudhry A, Kamanaka M, Kobayashi Y, Booth CJ, Rudensky AY, Roncarolo MG, Battaglia M, Flavell RA: Th17 cells express interleukin-10 receptor and are controlled by Foxp3⁻ and Foxp3+ regulatory CD4+ T cells in an interleukin-10-dependent manner. Immunity. 2011 Apr 22. PMID: 21511184

Zhu Y, Yao S, Chen L: Cell surface signaling molecules in the control of immune responses: a tide model. Immunity. 2011 Apr 22. PMID: 21511182

Orabi AI, Shah AU, Muili K, Luo Y, Mahmood SM, Ahmad A, Reed A, Husain SZ: Ethanol enhances carbachol-induced protease activation and accelerates Ca2+ waves in isolated rat pancreatic acini. J Biol Chem. 2011 Apr 22; 2011 Mar 3. PMID: 21372126

Wu YT, Ouyang W, Lazorchak AS, Liu D, Shen HM, Su B: mTOR complex 2 targets Akt for proteasomal degradation via phosphorylation at the hydrophobic motif. J Biol Chem. 2011 Apr 22; 2011 Feb 14. PMID: 21321111

Li N, Liu RJ, Dwyer JM, Banasr M, Lee B, Son H, Li XY, Aghajanian G, Duman RS: Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure. Biol Psychiatry. 2011 Apr 15; 2011 Feb 3. PMID: 21292242

Francis SS, Sfakianos J, Lo B, Mellman I: A hierarchy of signals regulates entry of membrane proteins into the ciliary membrane domain in epithelial cells. J Cell Biol. 2011 Apr 4; 2011 Mar 28. PMID: 21444686

Smith KD, Strobel SA: Interactions of the c-di-GMP riboswitch with its second messenger ligand. Biochem Soc Trans. 2011 Apr. PMID: 21428955

Alicea-Velázquez NL, Boggon TJ: The use of structural biology in Janus kinase targeted drug discovery. Curr Drug Targets. 2011 Apr. PMID: 21126226

Gan X, Wang J, Su B, Wu D: Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem. 2011 Apr 1; 2011 Feb 10. PMID: 21310961

McGinley MJ, Westbrook GL: Membrane and synaptic properties of pyramidal neurons in the anterior olfactory nucleus. J Neurophysiol. 2011 Apr; 2010 Dec 1. PMID: 21123663

Dominguez-Villar M, Hafler DA: Immunology. An innate role for IL-17. Science. 2011 Apr 1. PMID: 21454778

Louvi A, Grove EA: Cilia in the CNS: the quiet organelle claims center stage. Neuron. 2011 Mar 24. PMID: 21435552

Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H: MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline. Dev Cell. 2011 Mar 15. PMID: 21397847

Muto A, Yi T, Harrison KD, Dávalos A, Fancher TT, Ziegler KR, Feigel A, Kondo Y, Nishibe T, Sessa WC, Dardik A: Eph-B4 prevents venous adaptive remodeling in the adult arterial environment. J Exp Med. 2011 Mar 14; 2011 Feb 21. PMID: 21339325

Hashimoto-Torii K, Kawasawa YI, Kuhn A, Rakic P: Combined transcriptome analysis of fetal human and mouse cerebral cortex exposed to alcohol. Proc Natl Acad Sci U S A. 2011 Mar 8; 2011 Feb 22. PMID: 21368140

Bai JP, Surguchev A, Navaratnam D: β4-subunit increases Slo responsiveness to physiological Ca2+ concentrations and together with β1 reduces surface expression of Slo in hair cells. Am J Physiol Cell Physiol. 2011 Mar; 2010 Dec 22. PMID: 21178105

Walther Z, Sklar J: Molecular tumor profiling for prediction of response to anticancer therapies. Cancer J. 2011 Mar-Apr. PMID: 21427550

Kim SJ, Kelly WK, Fu A, Haines K, Hoffman A, Zheng T, Zhu Y: Genome-wide methylation analysis identifies involvement of TNF-α mediated cancer pathways in prostate cancer. Cancer Lett. 2011 Mar 1; 2011 Jan 14. PMID: 21237555

Mader CC, Oser M, Magalhaes MA, Bravo-Cordero JJ, Condeelis J, Koleske AJ, Gil-Henn H: An EGFR-Src-Arg-cortactin pathway mediates functional maturation of invadopodia and breast cancer cell invasion. Cancer Res. 2011 Mar 1; 2011 Jan 21. PMID: 21257711

Li T, Yang Y, Canessa CM: Asp433 in the closing gate of ASIC1 determines stability of the open state without changing properties of the selectivity filter or Ca2+ block. J Gen Physiol. 2011 Mar. PMID: 21357733

Lee SY, Buhimschi IA, Dulay AT, Ali UA, Zhao G, Abdel-Razeq SS, Bahtiyar MO, Thung SF, Funai EF, Buhimschi CS: IL-6 trans-signaling system in intra-amniotic inflammation, preterm birth, and preterm premature rupture of the membranes. J Immunol. 2011 Mar 1; 2011 Jan 31. PMID: 21282511

Lee JH, Kim WT: Regulation of abiotic stress signal transduction by E3 ubiquitin ligases in Arabidopsis. Mol Cells. 2011 Mar; 2011 Jan 18. PMID: 21347703

Waters KA, Reinke V: Extrinsic and intrinsic control of germ cell proliferation in Caenorhabditis elegans. Mol Reprod Dev. 2011 Mar; 2011 Feb 17. PMID: 21337453

Staton AA, Knaut H, Giraldez AJ: miRNA regulation of Sdf1 chemokine signaling provides genetic robustness to germ cell migration. Nat Genet. 2011 Mar; 2011 Jan 23. PMID: 21258340

Neugebauer NM, Henehan RM, Hales CA, Picciotto MR: Mice lacking the galanin gene show decreased sensitivity to nicotine conditioned place preference. Pharmacol Biochem Behav. 2011 Mar; 2010 Dec 21. PMID: 21172385

Chang X, Liu F, Wang X, Lin A, Zhao H, Su B: The kinases MEKK2 and MEKK3 regulate transforming growth factor-β-mediated helper T cell differentiation. Immunity. 2011 Feb 25; 2011 Feb 17. PMID: 21333552

Di Lorenzo A, Manes TD, Davalos A, Wright PL, Sessa WC: Endothelial reticulon-4B (Nogo-B) regulates ICAM-1-mediated leukocyte transmigration and acute inflammation. Blood. 2011 Feb 17; 2010 Dec 23. PMID: 21183689

Shen H, Ferguson SM, Dephoure N, Park R, Yang Y, Volpicelli-Daley L, Gygi S, Schlessinger J, De Camilli P: Constitutive activated Cdc42-associated kinase (Ack) phosphorylation at arrested endocytic clathrin-coated pits of cells that lack dynamin. Mol Biol Cell. 2011 Feb 15; 2010 Dec 17. PMID: 21169560

Bouaouina M, Calderwood DA: Kindlins. Curr Biol. 2011 Feb 8. PMID: 21300280

Manes TD, Pober JS: Identification of endothelial cell junctional proteins and lymphocyte receptors involved in transendothelial migration of human effector memory CD4+ T cells. J Immunol. 2011 Feb 1; 2010 Dec 29. PMID: 21191062

Kulkarni MV, Franklin DS: N-Myc is a downstream target of RET signaling and is required for transcriptional regulation of p18(Ink4c) by the transforming mutant RET(C634R). Mol Oncol. 2011 Feb; 2010 Nov 5. PMID: 21112821

Lal M, Caplan M: Regulated intramembrane proteolysis: signaling pathways and biological functions. Physiology (Bethesda). 2011 Feb. PMID: 21357901

Zhang H, He H, Wang X, Wang X, Yang X, Li L, Deng XW: Genome-wide mapping of the HY5-mediated gene networks in Arabidopsis that involve both transcriptional and post-transcriptional regulation. Plant J. 2011 Feb; 2010 Dec 30. PMID: 21265889

Lee JH, Terzaghi W, Deng XW: DWA3, an Arabidopsis DWD protein, acts as a negative regulator in ABA signal transduction. Plant Sci. 2011 Feb; 2010 Oct 21. PMID: 21421380

Keramati AR, Singh R, Lin A, Faramarzi S, Ye ZJ, Mane S, Tellides G, Lifton RP, Mani A: Wild-type LRP6 inhibits, whereas atherosclerosis-linked LRP6R611C increases PDGF-dependent vascular smooth muscle cell proliferation. Proc Natl Acad Sci U S A. 2011 Feb 1; 2011 Jan 18. PMID: 21245321

Reed AM, Husain SZ, Thrower E, Alexandre M, Shah A, Gorelick FS, Nathanson MH: Low extracellular pH induces damage in the pancreatic acinar cell by enhancing calcium signaling. J Biol Chem. 2011 Jan 21; 2010 Nov 17. PMID: 21084290

Schenten D, Medzhitov R: The control of adaptive immune responses by the innate immune system. Adv Immunol. 2011. PMID: 21569913

Doherty LF, Kwon HE, Taylor HS: Regulation of tryptophan 2,3-dioxygenase by HOXA10 enhances embryo viability through serotonin signaling. Am J Physiol Endocrinol Metab. 2011 Jan; 2010 Oct 19. PMID: 20959529

Hatanaka K, Simons M, Murakami M: Phosphorylation of VE-cadherin controls endothelial phenotypes via p120-catenin coupling and Rac1 activation. Am J Physiol Heart Circ Physiol. 2011 Jan; 2010 Oct 29. PMID: 21037229

Schatz DG, Swanson PC: V(D)J recombination: mechanisms of initiation. Annu Rev Genet. 2011; 2011 Aug 19. PMID: 21854230

Tao J, Kamanaka M, Hao J, Hao Z, Jiang X, Craft JE, Flavell RA, Wu Z, Hong Z, Zhao L, Yin Z: IL-10 signaling in CD4+ T cells is critical for the pathogenesis of collagen-induced arthritis. Arthritis Res Ther. 2011; 2011 Dec 22. PMID: 22192790

Sukumaran B, Mastronunzio JE, Narasimhan S, Fankhauser S, Uchil PD, Levy R, Graham M, Colpitts TM, Lesser CF, Fikrig E: Anaplasma phagocytophilum AptA modulates Erk1/2 signalling. Cell Microbiol. 2011 Jan; 2010 Aug 27. PMID: 20716207

Huber S, Schramm C: Role of activin A in the induction of Foxp3+ and Foxp3- CD4+ regulatory T cells. Crit Rev Immunol. 2011. PMID: 21395511

Diano S: New aspects of melanocortin signaling: a role for PRCP in α-MSH degradation. Front Neuroendocrinol. 2011 Jan; 2010 Oct 25. PMID: 20932857

Li H, Matte-Martone C, Tan HS, Venkatesan S, McNiff J, Demetris AJ, Jain D, Lakkis F, Rothstein D, Shlomchik WD: Graft-versus-host disease is independent of innate signaling pathways triggered by pathogens in host hematopoietic cells. J Immunol. 2011 Jan 1; 2010 Nov 22. PMID: 21098219

Fiedler MJ, Nathanson MH: The type I inositol 1,4,5-trisphosphate receptor interacts with protein 4.1N to mediate neurite formation through intracellular Ca waves. Neurosignals. 2011; 2011 Mar 10. PMID: 21389686

Bian S, Bai JP, Chapin H, Le Moellic C, Dong H, Caplan M, Sigworth FJ, Navaratnam DS: Interactions between β-catenin and the HSlo potassium channel regulates HSlo surface expression. PLoS One. 2011; 2011 Dec 14. PMID: 22194818

Trinko R, Gan G, Gao XB, Sears RM, Guarnieri DJ, DiLeone RJ: Erk1/2 mediates leptin receptor signaling in the ventral tegmental area. PLoS One. 2011; 2011 Nov 4. PMID: 22076135

Liang Y: SHARPIN negatively associates with TRAF2-mediated NFκB activation. PLoS One. 2011; 2011 Jul 29. PMID: 21829440

Willis AI, Sadowitz B, Fuse S, Maier KG, Lee TS, Wang XJ, Tuszynski GP, Sumpio BE, Gahtan V: Thrombospondin 1, fibronectin, and vitronectin are differentially dependent upon RAS, ERK1/2, and p38 for induction of vascular smooth muscle cell chemotaxis. Vasc Endovascular Surg. 2011 Jan. PMID: 21193465

Ramgolam VS, DeGregorio SD, Rao GK, Collinge M, Subaran SS, Markovic-Plese S, Pardi R, Bender JR: T cell LFA-1 engagement induces HuR-dependent cytokine mRNA stabilization through a Vav-1, Rac1/2, p38MAPK and MKK3 signaling cascade. PLoS One. 2010 Dec 29; 2010 Dec 29. PMID: 21206905

Lee S, Kim K, Zhou ZJ: Role of ACh-GABA cotransmission in detecting image motion and motion direction. Neuron. 2010 Dec 22. PMID: 21172616

de Lencastre A, Pincus Z, Zhou K, Kato M, Lee SS, Slack FJ: MicroRNAs both promote and antagonize longevity in C. elegans. Curr Biol. 2010 Dec 21; 2010 Dec 2. PMID: 21129974

Aziz SA, Jilaveanu LB, Zito C, Camp RL, Rimm DL, Conrad P, Kluger HM: Vertical targeting of the phosphatidylinositol-3 kinase pathway as a strategy for treating melanoma. Clin Cancer Res. 2010 Dec 15. PMID: 21169255

Dib-Hajj SD, Waxman SG: Isoform-specific and pan-channel partners regulate trafficking and plasma membrane stability; and alter sodium channel gating properties. Neurosci Lett. 2010 Dec 10; 2010 Sep 17. PMID: 20817075

Jones D, Xu Z, Zhang H, He Y, Kluger MS, Chen H, Min W: Functional analyses of the bone marrow kinase in the X chromosome in vascular endothelial growth factor-induced lymphangiogenesis. Arterioscler Thromb Vasc Biol. 2010 Dec; 2010 Sep 23. PMID: 20864667

Hedhli N, Russell KS: Cytostatic drugs, neuregulin activation of erbB receptors, and angiogenesis. Curr Hypertens Rep. 2010 Dec. PMID: 20878505

Rothlin CV, Lemke G: TAM receptor signaling and autoimmune disease. Curr Opin Immunol. 2010 Dec; 2010 Oct 26. PMID: 21030229

Roth Flach RJ, Bennett AM: Mitogen-activated protein kinase phosphatase-1 - a potential therapeutic target in metabolic disease. Expert Opin Ther Targets. 2010 Dec. PMID: 21058921

Ye J, Gradoville L, Miller G: Cellular immediate-early gene expression occurs kinetically upstream of Epstein-Barr virus bzlf1 and brlf1 following cross-linking of the B cell antigen receptor in the Akata Burkitt lymphoma cell line. J Virol. 2010 Dec; 2010 Sep 22. PMID: 20861250

Alves DS, Farr GA, Seo-Mayer P, Caplan MJ: AS160 associates with the Na+,K+-ATPase and mediates the adenosine monophosphate-stimulated protein kinase-dependent regulation of sodium pump surface expression. Mol Biol Cell. 2010 Dec; 2010 Oct 13. PMID: 20943949

Mineur YS, Picciotto MR: Nicotine receptors and depression: revisiting and revising the cholinergic hypothesis. Trends Pharmacol Sci. 2010 Dec; 2010 Oct 19. PMID: 20965579

Higley MJ, Strittmatter SM: Neuroscience. Lynx for braking plasticity. Science. 2010 Nov 26. PMID: 21109660

Chapin HC, Caplan MJ: The cell biology of polycystic kidney disease. J Cell Biol. 2010 Nov 15. PMID: 21079243

Greten-Harrison B, Polydoro M, Morimoto-Tomita M, Diao L, Williams AM, Nie EH, Makani S, Tian N, Castillo PE, Buchman VL, Chandra SS: αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction. Proc Natl Acad Sci U S A. 2010 Nov 9; 2010 Oct 25. PMID: 20974939

Kucera K, Koblansky AA, Saunders LP, Frederick KB, De La Cruz EM, Ghosh S, Modis Y: Structure-based analysis of Toxoplasma gondii profilin: a parasite-specific motif is required for recognition by Toll-like receptor 11. J Mol Biol. 2010 Nov 5; 2010 Sep 17. PMID: 20851125

Thomson TC, Johnson J: Inducible somatic oocyte destruction in response to rapamycin requires wild-type regulation of follicle cell epithelial polarity. Cell Death Differ. 2010 Nov; 2010 May 7. PMID: 20448642

Buhimschi CS, Schatz F, Krikun G, Buhimschi IA, Lockwood CJ: Novel insights into molecular mechanisms of abruption-induced preterm birth. Expert Rev Mol Med. 2010 Nov 1; 2010 Nov 1. PMID: 21040617

Wangdi T, Mijares LA, Kazmierczak BI: In vivo discrimination of type 3 secretion system-positive and -negative Pseudomonas aeruginosa via a caspase-1-dependent pathway. Infect Immun. 2010 Nov; 2010 Sep 7. PMID: 20823203

Zhang K, Heidrich FM, DeGray B, Boehmerle W, Ehrlich BE: Paclitaxel accelerates spontaneous calcium oscillations in cardiomyocytes by interacting with NCS-1 and the InsP3R. J Mol Cell Cardiol. 2010 Nov; 2010 Aug 27. PMID: 20801127

Li J, Li G, Gao S, Martinez C, He G, Zhou Z, Huang X, Lee JH, Zhang H, Shen Y, Wang H, Deng XW: Arabidopsis transcription factor ELONGATED HYPOCOTYL5 plays a role in the feedback regulation of phytochrome A signaling. Plant Cell. 2010 Nov; 2010 Nov 19. PMID: 21097709

Alexander RP, Lowenthal AC, Harshey RM, Ottemann KM: CheV: CheW-like coupling proteins at the core of the chemotaxis signaling network. Trends Microbiol. 2010 Nov; 2010 Sep 9. PMID: 20832320

Rathinam C, Thien CB, Flavell RA, Langdon WY: Myeloid leukemia development in c-Cbl RING finger mutant mice is dependent on FLT3 signaling. Cancer Cell. 2010 Oct 19. PMID: 20951944

Shahbazian D, Parsyan A, Petroulakis E, Hershey J, Sonenberg N: eIF4B controls survival and proliferation and is regulated by proto-oncogenic signaling pathways. Cell Cycle. 2010 Oct 15; 2010 Oct 13. PMID: 20948310

Carrillo RA, Olsen DP, Yoon KS, Keshishian H: Presynaptic activity and CaMKII modulate retrograde semaphorin signaling and synaptic refinement. Neuron. 2010 Oct 6. PMID: 20920789

Bian S, Koo BW, Kelleher S, Santos-Sacchi J, Navaratnam DS: A highly expressing Tet-inducible cell line recapitulates in situ developmental changes in prestin's Boltzmann characteristics and reveals early maturational events. Am J Physiol Cell Physiol. 2010 Oct; 2010 Jul 14. PMID: 20631244

Wilken JA, Maihle NJ: Primary trastuzumab resistance: new tricks for an old drug. Ann N Y Acad Sci. 2010 Oct. PMID: 20973799

Lau OS, Deng XW: Plant hormone signaling lightens up: integrators of light and hormones. Curr Opin Plant Biol. 2010 Oct; 2010 Aug 23. PMID: 20739215

Smulders-Srinivasan TK, Szakmary A, Lin H: A Drosophila chromatin factor interacts with the Piwi-interacting RNA mechanism in niche cells to regulate germline stem cell self-renewal. Genetics. 2010 Oct; 2010 Jul 20. PMID: 20647505

Gilmore-Hebert M, Ramabhadran R, Stern DF: Interactions of ErbB4 and Kap1 connect the growth factor and DNA damage response pathways. Mol Cancer Res. 2010 Oct; 2010 Sep 21. PMID: 20858735

Wang P, Arjona A, Zhang Y, Sultana H, Dai J, Yang L, LeBlanc PM, Doiron K, Saleh M, Fikrig E: Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I. Nat Immunol. 2010 Oct; 2010 Sep 5. PMID: 20818395

Hand TW, Cui W, Jung YW, Sefik E, Joshi NS, Chandele A, Liu Y, Kaech SM: Differential effects of STAT5 and PI3K/AKT signaling on effector and memory CD8 T-cell survival. Proc Natl Acad Sci U S A. 2010 Sep 21; 2010 Sep 7. PMID: 20823247

Chairoungdua A, Smith DL, Pochard P, Hull M, Caplan MJ: Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling. J Cell Biol. 2010 Sep 20; 2010 Sep 13. PMID: 20837771

Sasai M, Linehan MM, Iwasaki A: Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3. Science. 2010 Sep 17. PMID: 20847273

Okamoto H, Voleti B, Banasr M, Sarhan M, Duric V, Girgenti MJ, Dileone RJ, Newton SS, Duman RS: Wnt2 expression and signaling is increased by different classes of antidepressant treatments. Biol Psychiatry. 2010 Sep 15; 2010 Jun 8. PMID: 20570247

Horowitz MC, Fretz JA, Lorenzo JA: How B cells influence bone biology in health and disease. Bone. 2010 Sep; 2010 Jun 18. PMID: 20601290

Kursawe R, Eszlinger M, Narayan D, Liu T, Bazuine M, Cali AM, D'Adamo E, Shaw M, Pierpont B, Shulman GI, Cushman SW, Sherman A, Caprio S: Cellularity and adipogenic profile of the abdominal subcutaneous adipose tissue from obese adolescents: association with insulin resistance and hepatic steatosis. Diabetes. 2010 Sep. PMID: 20805387

Jin C, Flavell RA: Molecular mechanism of NLRP3 inflammasome activation. J Clin Immunol. 2010 Sep; 2010 Jun 30. PMID: 20589420

Yu Y, Maureira C, Liu X, McCormick D: P/Q and N channels control baseline and spike-triggered calcium levels in neocortical axons and synaptic boutons. J Neurosci. 2010 Sep 1. PMID: 20810905

Smith KD, Lipchock SV, Livingston AL, Shanahan CA, Strobel SA: Structural and biochemical determinants of ligand binding by the c-di-GMP riboswitch . Biochemistry. 2010 Aug 31. PMID: 20690679

Tirziu D, Giordano FJ, Simons M: Cell communications in the heart. Circulation. 2010 Aug 31. PMID: 20805439

Zhou J, Tang PC, Qin L, Gayed PM, Li W, Skokos EA, Kyriakides TR, Pober JS, Tellides G: CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses. J Exp Med. 2010 Aug 30; 2010 Aug 23. PMID: 20733031

Walther TC, Mann M: Mass spectrometry-based proteomics in cell biology. J Cell Biol. 2010 Aug 23. PMID: 20733050

Li N, Lee B, Liu RJ, Banasr M, Dwyer JM, Iwata M, Li XY, Aghajanian G, Duman RS: mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science. 2010 Aug 20. PMID: 20724638

Lam W, Bussom S, Guan F, Jiang Z, Zhang W, Gullen EA, Liu SH, Cheng YC: The four-herb Chinese medicine PHY906 reduces chemotherapy-induced gastrointestinal toxicity. Sci Transl Med. 2010 Aug 18. PMID: 20720216

Kober H, Mende-Siedlecki P, Kross EF, Weber J, Mischel W, Hart CL, Ochsner KN: Prefrontal-striatal pathway underlies cognitive regulation of craving. Proc Natl Acad Sci U S A. 2010 Aug 17; 2010 Aug 2. PMID: 20679212

Horvath TL, Sarman B, García-Cáceres C, Enriori PJ, Sotonyi P, Shanabrough M, Borok E, Argente J, Chowen JA, Perez-Tilve D, Pfluger PT, Brönneke HS, Levin BE, Diano S, Cowley MA, Tschöp MH: Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity. Proc Natl Acad Sci U S A. 2010 Aug 17; 2010 Aug 2. PMID: 20679202

Letinic K, Sebastian R, Barthel A, Toomre D: Deciphering subcellular processes in live imaging datasets via dynamic probabilistic networks. Bioinformatics. 2010 Aug 15; 2010 Jun 26. PMID: 20581401

Lazorchak AS, Liu D, Facchinetti V, Di Lorenzo A, Sessa WC, Schatz DG, Su B: Sin1-mTORC2 suppresses rag and il7r gene expression through Akt2 in B cells. Mol Cell. 2010 Aug 13. PMID: 20705244

Lee ER, Baker JL, Weinberg Z, Sudarsan N, Breaker RR: An allosteric self-splicing ribozyme triggered by a bacterial second messenger. Science. 2010 Aug 13. PMID: 20705859

Zhang Y, Tang W, Jones MC, Xu W, Halene S, Wu D: Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils. J Biol Chem. 2010 Aug 6; 2010 Jun 4. PMID: 20525682

Rubenstein EM, Schmidt MC: The glucose signal and metabolic p[H+]lux. EMBO J. 2010 Aug 4. PMID: 20683466

Sultana H, Neelakanta G, Kantor FS, Malawista SE, Fish D, Montgomery RR, Fikrig E: Anaplasma phagocytophilum induces actin phosphorylation to selectively regulate gene transcription in Ixodes scapularis ticks. J Exp Med. 2010 Aug 2; 2010 Jul 26. PMID: 20660616

Shaw AC, Joshi S, Greenwood H, Panda A, Lord JM: Aging of the innate immune system. Curr Opin Immunol. 2010 Aug. PMID: 20667703

Flavell RA, Sanjabi S, Wrzesinski SH, Licona-Limón P: The polarization of immune cells in the tumour environment by TGFbeta. Nat Rev Immunol. 2010 Aug; 2010 Jul 9. PMID: 20616810

Duldulao NA, Li J, Sun Z: Cilia in cell signaling and human disorders. Protein Cell. 2010 Aug; 2010 Aug 28. PMID: 21203914

Mehal W, Imaeda A: Cell death and fibrogenesis. Semin Liver Dis. 2010 Aug; 2010 Jul 21. PMID: 20665375

D'Alessio A, Kluger MS, Li JH, Al-Lamki R, Bradley JR, Pober JS: Targeting of tumor necrosis factor receptor 1 to low density plasma membrane domains in human endothelial cells. J Biol Chem. 2010 Jul 30; 2010 May 28. PMID: 20511226

Li T, Yang Y, Canessa CM: Leu85 in the beta1-beta2 linker of ASIC1 slows activation and decreases the apparent proton affinity by stabilizing a closed conformation. J Biol Chem. 2010 Jul 16; 2010 May 17. PMID: 20479002

Li T, Yang Y, Canessa CM: Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel. Am J Physiol Cell Physiol. 2010 Jul; 2010 Apr 28. PMID: 20427715

Cruz LN, Guerra MT, Kruglov E, Mennone A, Garcia CR, Chen J, Nathanson MH: Regulation of multidrug resistance-associated protein 2 by calcium signaling in mouse liver. Hepatology. 2010 Jul. PMID: 20578149

Corson TW: Medichem--BIT Life Sciences' First Annual International Conference. IDrugs. 2010 Jul. PMID: 20582869

Cabeen MT, Murolo MA, Briegel A, Bui NK, Vollmer W, Ausmees N, Jensen GJ, Jacobs-Wagner C: Mutations in the Lipopolysaccharide biosynthesis pathway interfere with crescentin-mediated cell curvature in Caulobacter crescentus. J Bacteriol. 2010 Jul; 2010 Apr 30. PMID: 20435724

Brown MR, Kronengold J, Gazula VR, Chen Y, Strumbos JG, Sigworth FJ, Navaratnam D, Kaczmarek LK: Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack. Nat Neurosci. 2010 Jul; 2010 May 30. PMID: 20512134

Ota KT, Monsey MS, Wu MS, Schafe GE: Synaptic plasticity and NO-cGMP-PKG signaling regulate pre- and postsynaptic alterations at rat lateral amygdala synapses following fear conditioning. PLoS One. 2010 Jun 21; 2010 Jun 21. PMID: 20574537

Yin G, Chen R, Alvero AB, Fu HH, Holmberg J, Glackin C, Rutherford T, Mor G: TWISTing stemness, inflammation and proliferation of epithelial ovarian cancer cells through MIR199A2/214. Oncogene. 2010 Jun 17; 2010 Apr 19. PMID: 20400975

Sears RM, Liu RJ, Narayanan NS, Sharf R, Yeckel MF, Laubach M, Aghajanian GK, DiLeone RJ: Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone. J Neurosci. 2010 Jun 16. PMID: 20554878

Lin Q, Yun Z: Impact of the hypoxic tumor microenvironment on the regulation of cancer stem cell characteristics. Cancer Biol Ther. 2010 Jun 15; 2010 Jun 11. PMID: 20581454

Contessa JN, Bhojani MS, Freeze HH, Ross BD, Rehemtulla A, Lawrence TS: Molecular imaging of N-linked glycosylation suggests glycan biosynthesis is a novel target for cancer therapy. Clin Cancer Res. 2010 Jun 15; 2010 Apr 22. PMID: 20413434

Buhimschi IA, Buhimschi CS: The role of proteomics in the diagnosis of chorioamnionitis and early-onset neonatal sepsis. Clin Perinatol. 2010 Jun. PMID: 20569812

Braddock DT: Autotaxin and lipid signaling pathways as anticancer targets. Curr Opin Investig Drugs. 2010 Jun. PMID: 20496257

Lo TW, Bennett DC, Goodman SJ, Stern MJ: Caenorhabditis elegans fibroblast growth factor receptor signaling can occur independently of the multi-substrate adaptor FRS2. Genetics. 2010 Jun; 2010 Mar 22. PMID: 20308281

Archer KA, Ader F, Kobayashi KS, Flavell RA, Roy CR: Cooperation between multiple microbial pattern recognition systems is important for host protection against the intracellular pathogen Legionella pneumophila. Infect Immun. 2010 Jun; 2010 Mar 29. PMID: 20351139

Estacion M, Choi JS, Eastman EM, Lin Z, Li Y, Tyrrell L, Yang Y, Dib-Hajj SD, Waxman SG: Can robots patch-clamp as well as humans? Characterization of a novel sodium channel mutation. J Physiol. 2010 Jun 1; 2010 Feb 1. PMID: 20123784

Veron D, Reidy KJ, Bertuccio C, Teichman J, Villegas G, Jimenez J, Shen W, Kopp JB, Thomas DB, Tufro A: Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease. Kidney Int. 2010 Jun; 2010 Mar 10. PMID: 20375978

Lee JH, Yoon HJ, Terzaghi W, Martinez C, Dai M, Li J, Byun MO, Deng XW: DWA1 and DWA2, two Arabidopsis DWD protein components of CUL4-based E3 ligases, act together as negative regulators in ABA signal transduction. Plant Cell. 2010 Jun; 2010 Jun 4. PMID: 20525848

Fogal B, McClaskey C, Yan S, Yan H, Rivkees SA: Diazoxide promotes oligodendrocyte precursor cell proliferation and myelination. PLoS One. 2010 May 28; 2010 May 28. PMID: 20531945

Strumbos JG, Polley DB, Kaczmarek LK: Specific and rapid effects of acoustic stimulation on the tonotopic distribution of Kv3.1b potassium channels in the adult rat. Neuroscience. 2010 May 19; 2010 Feb 26. PMID: 20219640

Rathinam C, Flavell RA: c-Cbl deficiency leads to diminished lymphocyte development and functions in an age-dependent manner. Proc Natl Acad Sci U S A. 2010 May 4; 2010 Apr 19. PMID: 20404156

Mulla MJ, Myrtolli K, Brosens JJ, Chamley LW, Kwak-Kim JY, Paidas MJ, Abrahams VM: Antiphospholipid antibodies limit trophoblast migration by reducing IL-6 production and STAT3 activity. Am J Reprod Immunol. 2010 May; 2010 Feb 3. PMID: 20132164

Saif MW, Chu E: Biology of colorectal cancer. Cancer J. 2010 May-Jun. PMID: 20526096

Chidlow JH Jr, Sessa WC: Caveolae, caveolins, and cavins: complex control of cellular signalling and inflammation. Cardiovasc Res. 2010 May 1; 2010 Mar 3. PMID: 20202978

Rinehart J, Gulcicek EE, Joiner CH, Lifton RP, Gallagher PG: Determinants of erythrocyte hydration. Curr Opin Hematol. 2010 May. PMID: 20182354

Kaczmarek LK: Controlling auditory excitability: the benefits of a cultured environment. J Physiol. 2010 May 1. PMID: 20436041

Choi C, Nitabach MN: Circadian biology: environmental regulation of a multi-oscillator network. Curr Biol. 2010 Apr 13. PMID: 20392424

Ju R, Cirone P, Lin S, Griesbach H, Slusarski DC, Crews CM: Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis. Proc Natl Acad Sci U S A. 2010 Apr 13; 2010 Mar 29. PMID: 20351293

He Y, Zhang H, Yu L, Gunel M, Boggon TJ, Chen H, Min W: Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development. Sci Signal. 2010 Apr 6; 2010 Apr 6. PMID: 20371769

Chakraborty AK, Welsh A, Digiovanna MP: Co-targeting the insulin-like growth factor I receptor enhances growth-inhibitory and pro-apoptotic effects of anti-estrogens in human breast cancer cell lines. Breast Cancer Res Treat. 2010 Apr; 2009 Apr 1. PMID: 19337828

Hoffman AE, Zheng T, Yi CH, Stevens RG, Ba Y, Zhang Y, Leaderer D, Holford T, Hansen J, Zhu Y: The core circadian gene Cryptochrome 2 influences breast cancer risk, possibly by mediating hormone signaling. Cancer Prev Res (Phila). 2010 Apr; 2010 Mar 16. PMID: 20233903

Kasinski AL, Slack FJ: Potential microRNA therapies targeting Ras, NFkappaB and p53 signaling. Curr Opin Mol Ther. 2010 Apr. PMID: 20373258

Dranoff JA, Wells RG: Portal fibroblasts: Underappreciated mediators of biliary fibrosis. Hepatology. 2010 Apr. PMID: 20209607

Tan AM, Chen HC, Pochard P, Eisenbarth SC, Herrick CA, Bottomly HK: TLR4 signaling in stromal cells is critical for the initiation of allergic Th2 responses to inhaled antigen. J Immunol. 2010 Apr 1; 2010 Mar 1. PMID: 20194715

Girgenti MJ, Nisenbaum LK, Bymaster F, Terwilliger R, Duman RS, Newton SS: Antipsychotic-induced gene regulation in multiple brain regions. J Neurochem. 2010 Apr; 2010 Jan 13. PMID: 20070867

Chiswell BP, Stiegler AL, Razinia Z, Nalibotski E, Boggon TJ, Calderwood DA: Structural basis of competition between PINCH1 and PINCH2 for binding to the ankyrin repeat domain of integrin-linked kinase. J Struct Biol. 2010 Apr; 2009 Dec 4. PMID: 19963065

Ota KT, Monsey MS, Wu MS, Young GJ, Schafe GE: Synaptic plasticity and NO-cGMP-PKG signaling coordinately regulate ERK-driven gene expression in the lateral amygdala and in the auditory thalamus following Pavlovian fear conditioning. Learn Mem. 2010 Apr; 2010 Mar 29. PMID: 20351057

Liu X, Hashimoto-Torii K, Torii M, Ding C, Rakic P: Gap junctions/hemichannels modulate interkinetic nuclear migration in the forebrain precursors. J Neurosci. 2010 Mar 24. PMID: 20335455

Zhao Z, Fan L, Frick KM: Epigenetic alterations regulate estradiol-induced enhancement of memory consolidation. Proc Natl Acad Sci U S A. 2010 Mar 23; 2010 Mar 8. PMID: 20212170

Gao XB, Wang AH: Experience-dependent plasticity in hypocretin/orexin neurones: re-setting arousal threshold. Acta Physiol (Oxf). 2010 Mar; 2009 Sep 24. PMID: 19785627

Gallagher AR, Germino GG, Somlo S: Molecular advances in autosomal dominant polycystic kidney disease. Adv Chronic Kidney Dis. 2010 Mar. PMID: 20219615

Sanacora G: Cortical inhibition, gamma-aminobutyric acid, and major depression: there is plenty of smoke but is there fire? Biol Psychiatry. 2010 Mar 1. PMID: 20159143

Bandi P, Pagliaccetti NE, Robek MD: Inhibition of type III interferon activity by orthopoxvirus immunomodulatory proteins. J Interferon Cytokine Res. 2010 Mar. PMID: 20038204

Rampias T, Boutati E, Pectasides E, Sasaki C, Kountourakis P, Weinberger P, Psyrri A: Activation of Wnt signaling pathway by human papillomavirus E6 and E7 oncogenes in HPV16-positive oropharyngeal squamous carcinoma cells. Mol Cancer Res. 2010 Mar; 2010 Mar 9. PMID: 20215420

McCarthy TL, Centrella M: Novel links among Wnt and TGF-beta signaling and Runx2. Mol Endocrinol. 2010 Mar; 2010 Jan 21. PMID: 20093419

Mara CD, Huang T, Irish VF: The Arabidopsis floral homeotic proteins APETALA3 and PISTILLATA negatively regulate the BANQUO genes implicated in light signaling. Plant Cell. 2010 Mar; 2010 Mar 19. PMID: 20305124

Wang DH, Li F, Duan QH, Han T, Xu ZH, Bai SN: Ethylene perception is involved in female cucumber flower development. Plant J. 2010 Mar; 2009 Dec 21. PMID: 20030751

Wu D, Pan W: GSK3: a multifaceted kinase in Wnt signaling. Trends Biochem Sci. 2010 Mar; 2009 Oct 31. PMID: 19884009

Sanjabi S, Flavell RA: Overcoming the hurdles in using mouse genetic models that block TGF-beta signaling. J Immunol Methods. 2010 Feb 28; 2010 Jan 11. PMID: 20060833

Xu HP, Chen H, Ding Q, Xie ZH, Chen L, Diao L, Wang P, Gan L, Crair MC, Tian N: The immune protein CD3zeta is required for normal development of neural circuits in the retina. Neuron. 2010 Feb 25. PMID: 20188655

Bae JH, Boggon TJ, Tomé F, Mandiyan V, Lax I, Schlessinger J: Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells. Proc Natl Acad Sci U S A. 2010 Feb 16; 2010 Jan 26. PMID: 20133753

Nickerson KM, Christensen SR, Shupe J, Kashgarian M, Kim D, Elkon K, Shlomchik MJ: TLR9 regulates TLR7- and MyD88-dependent autoantibody production and disease in a murine model of lupus. J Immunol. 2010 Feb 15; 2010 Jan 20. PMID: 20089701

Koo JW, Russo SJ, Ferguson D, Nestler EJ, Duman RS: Nuclear factor-kappaB is a critical mediator of stress-impaired neurogenesis and depressive behavior. Proc Natl Acad Sci U S A. 2010 Feb 9; 2010 Jan 26. PMID: 20133768

Stamboulian S, Choi JS, Ahn HS, Chang YW, Tyrrell L, Black JA, Waxman SG, Dib-Hajj SD: ERK1/2 mitogen-activated protein kinase phosphorylates sodium channel Na(v)1.7 and alters its gating properties. J Neurosci. 2010 Feb 3. PMID: 20130174

Yang Y, Xie P, Opatowsky Y, Schlessinger J: Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling. Proc Natl Acad Sci U S A. 2010 Feb 2; 2010 Jan 11. PMID: 20080685

Akhtar S, Barash PG, Inzucchi SE: Scientific principles and clinical implications of perioperative glucose regulation and control. Anesth Analg. 2010 Feb 1. PMID: 20081134

Nishio S, Tian X, Gallagher AR, Yu Z, Patel V, Igarashi P, Somlo S: Loss of oriented cell division does not initiate cyst formation. J Am Soc Nephrol. 2010 Feb; 2009 Dec 3. PMID: 19959710

Nowak LG, Sanchez-Vives MV, McCormick DA: Spatial and temporal features of synaptic to discharge receptive field transformation in cat area 17. J Neurophysiol. 2010 Feb; 2009 Nov 11. PMID: 19906874

Tomita S: Regulation of ionotropic glutamate receptors by their auxiliary subunits. Physiology (Bethesda). 2010 Feb. PMID: 20134027

Wu M, Pastor-Pareja JC, Xu T: Interaction between Ras(V12) and scribbled clones induces tumour growth and invasion. Nature. 2010 Jan 28; 2010 Jan 13. PMID: 20072127

Porter MY, Koelle MR: RSBP-1 is a membrane-targeting subunit required by the Galpha(q)-specific but not the Galpha(o)-specific R7 regulator of G protein signaling in Caenorhabditis elegans. Mol Biol Cell. 2010 Jan 15; 2009 Nov 18. PMID: 19923320

Iwasaki A, Medzhitov R: Regulation of adaptive immunity by the innate immune system. Science. 2010 Jan 15. PMID: 20075244

Haider B, Krause MR, Duque A, Yu Y, Touryan J, Mazer JA, McCormick DA: Synaptic and network mechanisms of sparse and reliable visual cortical activity during nonclassical receptive field stimulation. Neuron. 2010 Jan 14. PMID: 20152117

Yuan J, Chen J: MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX. J Biol Chem. 2010 Jan 8; 2009 Nov 12. PMID: 19910469

El-Sahwi K, Bellone S, Cocco E, Cargnelutti M, Casagrande F, Bellone M, Abu-Khalaf M, Buza N, Tavassoli FA, Hui P, Silasi DA, Azodi M, Schwartz PE, Rutherford TJ, Pecorelli S, Santin AD: In vitro activity of pertuzumab in combination with trastuzumab in uterine serous papillary adenocarcinoma. Br J Cancer. 2010 Jan 5; 2009 Nov 17. PMID: 19920829

Ma S, Kosorok MR: Detection of gene pathways with predictive power for breast cancer prognosis. BMC Bioinformatics. 2010 Jan 1; 2010 Jan 1. PMID: 20043860

Triano LR, Deshpande H, Gettinger SN: Management of patients with advanced non-small cell lung cancer: current and emerging options. Drugs. 2010. PMID: 20108990

Narayanan NS, Guarnieri DJ, DiLeone RJ: Metabolic hormones, dopamine circuits, and feeding. Front Neuroendocrinol. 2010 Jan; 2009 Oct 28. PMID: 19836414

Spirli C, Okolicsanyi S, Fiorotto R, Fabris L, Cadamuro M, Lecchi S, Tian X, Somlo S, Strazzabosco M: ERK1/2-dependent vascular endothelial growth factor signaling sustains cyst growth in polycystin-2 defective mice. Gastroenterology. 2010 Jan; 2009 Sep 18. PMID: 19766642

Angelastro PS, Sliusarenko O, Jacobs-Wagner C: Polar localization of the CckA histidine kinase and cell cycle periodicity of the essential master regulator CtrA in Caulobacter crescentus. J Bacteriol. 2010 Jan; 2009 Nov 6. PMID: 19897656

Min W, Xu LK, Zhou HJ, Huang Q, Zhang H, He Y, Zhe X, Luo Y: Thioredoxin and redox signaling in vasculature-studies using Trx2 endothelium-specific transgenic mice. Methods Enzymol. 2010; 2010 Jun 20. PMID: 20609919

Ping J, Schafe GE: The NO-cGMP-PKG signaling pathway coordinately regulates ERK and ERK-driven gene expression at pre- and postsynaptic sites following LTP-inducing stimulation of thalamo-amygdala synapses. Neural Plast. 2010; 2011 Feb 20. PMID: 21461354

de Araujo IE, Ren X, Ferreira JG: Metabolic sensing in brain dopamine systems. Results Probl Cell Differ. 2010. PMID: 20865373

Kampe J, Tschöp M, Horvath TL, Widmer P, De Groot LJ, Chrousos G, Dungan K, Feingold KR, Grossman A, Hershman JM, Koch C, Korbonits M, McLachlan R, New M, Purnell J, Rebar R, Singer F, Vinik A: Neuroendocrine Integration of Body Weight Regulation 2000. PMID: 25905269

De Camilli P, Carew TJ: Nobel celebrates the neurosciences. Modulatory signaling in the brain. Cell. 2000 Dec 8. PMID: 11136967

Fischer TM, Yuan JW, Carew TJ: Dynamic regulation of the siphon withdrawal reflex of Aplysia californica in response to changes in the ambient tactile environment. Behav Neurosci. 2000 Dec. PMID: 11142653

DiMaio D, Lai CC, Mattoon D: The platelet-derived growth factor beta receptor as a target of the bovine papillomavirus E5 protein. Cytokine Growth Factor Rev. 2000 Dec. PMID: 10959076

Hoffman GA, Garrison TR, Dohlman HG: Endoproteolytic processing of Sst2, a multidomain regulator of G protein signaling in yeast. J Biol Chem. 2000 Dec 1. PMID: 10982801

Stebbins CE, Galán JE: Modulation of host signaling by a bacterial mimic: structure of the Salmonella effector SptP bound to Rac1. Mol Cell. 2000 Dec. PMID: 11163217

Czyzyk J, Leitenberg D, Taylor T, Bottomly K: Combinatorial effect of T-cell receptor ligation and CD45 isoform expression on the signaling contribution of the small GTPases Ras and Rap1. Mol Cell Biol. 2000 Dec. PMID: 11073975

Bucci M, Gratton JP, Rudic RD, Acevedo L, Roviezzo F, Cirino G, Sessa WC: In vivo delivery of the caveolin-1 scaffolding domain inhibits nitric oxide synthesis and reduces inflammation. Nat Med. 2000 Dec. PMID: 11100121

Leiserson WM, Harkins EW, Keshishian H: Fray, a Drosophila serine/threonine kinase homologous to mammalian PASK, is required for axonal ensheathment. Neuron. 2000 Dec. PMID: 11163267

Schwechheimer C, Deng XW: The COP/DET/FUS proteins-regulators of eukaryotic growth and development. Semin Cell Dev Biol. 2000 Dec. PMID: 11145879

Berghs S, Aggujaro D, Dirkx R Jr, Maksimova E, Stabach P, Hermel JM, Zhang JP, Philbrick W, Slepnev V, Ort T, Solimena M: betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous system. J Cell Biol. 2000 Nov 27. PMID: 11086001

Goodwin EC, DiMaio D: Repression of human papillomavirus oncogenes in HeLa cervical carcinoma cells causes the orderly reactivation of dormant tumor suppressor pathways. Proc Natl Acad Sci U S A. 2000 Nov 7. PMID: 11070078

Wells RG: Fibrogenesis. V. TGF-beta signaling pathways. Am J Physiol Gastrointest Liver Physiol. 2000 Nov. PMID: 11052979

Voll RE, Jimi E, Phillips RJ, Barber DF, Rincon M, Hayday AC, Flavell RA, Ghosh S: NF-kappa B activation by the pre-T cell receptor serves as a selective survival signal in T lymphocyte development. Immunity. 2000 Nov. PMID: 11114380

Zilberberg N, Ilan N, Gonzalez-Colaso R, Goldstein SA: Opening and closing of KCNKO potassium leak channels is tightly regulated. J Gen Physiol. 2000 Nov. PMID: 11055999

Gorelik L, Fields PE, Flavell RA: Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression. J Immunol. 2000 Nov 1. PMID: 11045997

Gu XQ, Yao H, Haddad GG: Effect of extracellular HCO(3)(-) on Na(+) channel characteristics in hippocampal CA1 neurons. J Neurophysiol. 2000 Nov. PMID: 11067990

Alreja M, Wu M, Liu W, Atkins JB, Leranth C, Shanabrough M: Muscarinic tone sustains impulse flow in the septohippocampal GABA but not cholinergic pathway: implications for learning and memory. J Neurosci. 2000 Nov 1. PMID: 11050132

Leckman JF, Riddle MA: Tourette's syndrome: when habit-forming systems form habits of their own? Neuron. 2000 Nov. PMID: 11144345

Birnbaum SG, Podell DM, Arnsten AF: Noradrenergic alpha-2 receptor agonists reverse working memory deficits induced by the anxiogenic drug, FG7142, in rats. Pharmacol Biochem Behav. 2000 Nov. PMID: 11164065

Galán JE: Alternative strategies for becoming an insider: lessons from the bacterial world. Cell. 2000 Oct 27. PMID: 11081622

Fujita M, Charney DS, Innis RB: Imaging serotonergic neurotransmission in depression: hippocampal pathophysiology may mirror global brain alterations. Biol Psychiatry. 2000 Oct 15. PMID: 11063976

Duman RS, Malberg J, Nakagawa S, D'Sa C: Neuronal plasticity and survival in mood disorders. Biol Psychiatry. 2000 Oct 15. PMID: 11063970

Nakayama Y, Iwamoto Y, Maher SE, Tanaka Y, Bothwell AL: Altered gene expression upon BCR cross-linking in Burkitt's lymphoma B cell line. Biochem Biophys Res Commun. 2000 Oct 14. PMID: 11027651

Haynes MP, Sinha D, Russell KS, Collinge M, Fulton D, Morales-Ruiz M, Sessa WC, Bender JR: Membrane estrogen receptor engagement activates endothelial nitric oxide synthase via the PI3-kinase-Akt pathway in human endothelial cells. Circ Res. 2000 Oct 13. PMID: 11029403

Burchett SA: Regulators of G protein signaling: a bestiary of modular protein binding domains. J Neurochem. 2000 Oct. PMID: 10987813

Azuma N, Duzgun SA, Ikeda M, Kito H, Akasaka N, Sasajima T, Sumpio BE: Endothelial cell response to different mechanical forces. J Vasc Surg. 2000 Oct. PMID: 11013043

Ehrhard KN, Jacoby JJ, Fu XY, Jahn R, Dohlman HG: Use of G-protein fusions to monitor integral membrane protein-protein interactions in yeast. Nat Biotechnol. 2000 Oct. PMID: 11017046

Medzhitov R, Janeway C Jr: The Toll receptor family and microbial recognition. Trends Microbiol. 2000 Oct. PMID: 11044679

Janeway C Jr, Medzhitov R: Viral interference with IL-1 and toll signaling. Proc Natl Acad Sci U S A. 2000 Sep 26. PMID: 11005852

Schnare M, Holt AC, Takeda K, Akira S, Medzhitov R: Recognition of CpG DNA is mediated by signaling pathways dependent on the adaptor protein MyD88. Curr Biol. 2000 Sep 21. PMID: 10996797

Bradberry CW: Acute and chronic dopamine dynamics in a nonhuman primate model of recreational cocaine use. J Neurosci. 2000 Sep 15. PMID: 10995858

Dong C, Flavell RA: Control of T helper cell differentiation--in search of master genes. Sci STKE. 2000 Sep 12; 2000 Sep 12. PMID: 11752608

Sesti F, Tai KK, Goldstein SA: MinK endows the I(Ks) potassium channel pore with sensitivity to internal tetraethylammonium. Biophys J. 2000 Sep. PMID: 10968999

Zeng M, Narayanan L, Xu XS, Prolla TA, Liskay RM, Glazer PM: Ionizing radiation-induced apoptosis via separate Pms2- and p53-dependent pathways. Cancer Res. 2000 Sep 1. PMID: 10987303

Ort T, Maksimova E, Dirkx R, Kachinsky AM, Berghs S, Froehner SC, Solimena M: The receptor tyrosine phosphatase-like protein ICA512 binds the PDZ domains of beta2-syntrophin and nNOS in pancreatic beta-cells. Eur J Cell Biol. 2000 Sep. PMID: 11043403

Sadeghi MM, Collinge M, Pardi R, Bender JR: Simvastatin modulates cytokine-mediated endothelial cell adhesion molecule induction: involvement of an inhibitory G protein. J Immunol. 2000 Sep 1. PMID: 10946302

Haynes MP, Russell KS, Bender JR: Molecular mechanisms of estrogen actions on the vasculature. J Nucl Cardiol. 2000 Sep-Oct. PMID: 11083200

Choi ME: Mechanism of transforming growth factor-beta1 signaling:. Kidney Int Suppl. 2000 Sep. PMID: 10997691

Rakic P: Illegal immigrations. Neuron. 2000 Sep. PMID: 11055419

Kang D, Wang X, Cao K, Sun C, Deng XW, Wei N: A gain-of-function phenotype conferred by over-expression of functional subunits of the COP9 signalosome in Arabidopsis. Plant J. 2000 Sep. PMID: 10972886

Dong MQ, Chase D, Patikoglou GA, Koelle MR: Multiple RGS proteins alter neural G protein signaling to allow C. elegans to rapidly change behavior when fed. Genes Dev. 2000 Aug 15. PMID: 10950865

Antic S, Wuskell JP, Loew L, Zecevic D: Functional profile of the giant metacerebral neuron of Helix aspersa: temporal and spatial dynamics of electrical activity in situ. J Physiol. 2000 Aug 15. PMID: 10944170

Dunbar LA, Caplan MJ: The cell biology of ion pumps: sorting and regulation. Eur J Cell Biol. 2000 Aug. PMID: 11001492

Lu M, MacGregor GG, Wang W, Giebisch G: Extracellular ATP inhibits the small-conductance K channel on the apical membrane of the cortical collecting duct from mouse kidney. J Gen Physiol. 2000 Aug. PMID: 10919872

Nakamura F, Kalb RG, Strittmatter SM: Molecular basis of semaphorin-mediated axon guidance. J Neurobiol. 2000 Aug. PMID: 10934324

Paul S, Snyder GL, Yokakura H, Picciotto MR, Nairn AC, Lombroso PJ: The Dopamine/D1 receptor mediates the phosphorylation and inactivation of the protein tyrosine phosphatase STEP via a PKA-dependent pathway. J Neurosci. 2000 Aug 1. PMID: 10908600

Gaeta ML, Johnson DR, Kluger MS, Pober JS: The death domain of tumor necrosis factor receptor 1 is necessary but not sufficient for Golgi retention of the receptor and mediates receptor desensitization. Lab Invest. 2000 Aug. PMID: 10950109

Hochstrasser M: Evolution and function of ubiquitin-like protein-conjugation systems. Nat Cell Biol. 2000 Aug. PMID: 10934491

Galan JE, Zhou D: Striking a balance: modulation of the actin cytoskeleton by Salmonella. Proc Natl Acad Sci U S A. 2000 Aug 1. PMID: 10922031

Ilan N, Cheung L, Pinter E, Madri JA: Platelet-endothelial cell adhesion molecule-1 (CD31), a scaffolding molecule for selected catenin family members whose binding is mediated by different tyrosine and serine/threonine phosphorylation. J Biol Chem. 2000 Jul 14. PMID: 10801826

McGlashan TH, Hoffman RE: Schizophrenia as a disorder of developmentally reduced synaptic connectivity. Arch Gen Psychiatry. 2000 Jul. PMID: 10891034

Fornaro M, Steger CA, Bennett AM, Wu JJ, Languino LR: Differential role of beta(1C) and beta(1A) integrin cytoplasmic variants in modulating focal adhesion kinase, protein kinase B/AKT, and Ras/Mitogen-activated protein kinase pathways. Mol Biol Cell. 2000 Jul. PMID: 10888665

Bailis JM, Smith AV, Roeder GS: Bypass of a meiotic checkpoint by overproduction of meiotic chromosomal proteins. Mol Cell Biol. 2000 Jul. PMID: 10848609

Wang Y, Wu TR, Cai S, Welte T, Chin YE: Stat1 as a component of tumor necrosis factor alpha receptor 1-TRADD signaling complex to inhibit NF-kappaB activation. Mol Cell Biol. 2000 Jul. PMID: 10848577

Woo DK, Dudrick SJ, Sumpio BE: Homocysteine stimulates MAP kinase in bovine aortic smooth muscle cells. Surgery. 2000 Jul. PMID: 10876187

Li B, Yu H, Zheng W, Voll R, Na S, Roberts AW, Williams DA, Davis RJ, Ghosh S, Flavell RA: Role of the guanosine triphosphatase Rac2 in T helper 1 cell differentiation. Science. 2000 Jun 23. PMID: 10864872

Li CS, Chen MC, Yang YY, Chang HL, Liu CY, Shen S, Chen CY: Perceptual alternation in obsessive compulsive disorder--implications for a role of the cortico-striatal circuitry in mediating awareness. Behav Brain Res. 2000 Jun 15. PMID: 10840132

Lopes CM, Gallagher PG, Buck ME, Butler MH, Goldstein SA: Proton block and voltage gating are potassium-dependent in the cardiac leak channel Kcnk3. J Biol Chem. 2000 Jun 2. PMID: 10748056

Beggs JM, Moyer JR Jr, McGann JP, Brown TH: Prolonged synaptic integration in perirhinal cortical neurons. J Neurophysiol. 2000 Jun. PMID: 10848549

Sanchez-Vives MV, Nowak LG, McCormick DA: Cellular mechanisms of long-lasting adaptation in visual cortical neurons in vitro. J Neurosci. 2000 Jun 1. PMID: 10818164

Sanchez-Vives MV, Nowak LG, McCormick DA: Membrane mechanisms underlying contrast adaptation in cat area 17 in vivo. J Neurosci. 2000 Jun 1. PMID: 10818163

Willis AI, Fuse S, Wang XJ, Chen E, Tuszynski GP, Sumpio BE, Gahtan V: Inhibition of phosphatidylinositol 3-kinase and protein kinase C attenuates extracellular matrix protein-induced vascular smooth muscle cell chemotaxis. J Vasc Surg. 2000 Jun. PMID: 10842153

Russell KS, Haynes MP, Sinha D, Clerisme E, Bender JR: Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling. Proc Natl Acad Sci U S A. 2000 May 23. PMID: 10823945

Wu M, Shanabrough M, Leranth C, Alreja M: Cholinergic excitation of septohippocampal GABA but not cholinergic neurons: implications for learning and memory. J Neurosci. 2000 May 15. PMID: 10804229

Dong C, Yang DD, Tournier C, Whitmarsh AJ, Xu J, Davis RJ, Flavell RA: JNK is required for effector T-cell function but not for T-cell activation. Nature. 2000 May 4. PMID: 10811224

Zhao HB, Santos-Sacchi J: Voltage gating of gap junctions in cochlear supporting cells: evidence for nonhomotypic channels. J Membr Biol. 2000 May 1. PMID: 10811964

Young LH, Coven DL, Russell RR 3rd: Cellular and molecular regulation of cardiac glucose transport. J Nucl Cardiol. 2000 May-Jun. PMID: 10888399

Morales-Ruiz M, Fulton D, Sowa G, Languino LR, Fujio Y, Walsh K, Sessa WC: Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt. Circ Res. 2000 Apr 28. PMID: 10785512

Fournier AE, Nakamura F, Kawamoto S, Goshima Y, Kalb RG, Strittmatter SM: Semaphorin3A enhances endocytosis at sites of receptor-F-actin colocalization during growth cone collapse. J Cell Biol. 2000 Apr 17. PMID: 10769032

Hingorani R, Bi B, Dao T, Bae Y, Matsuzawa A, Crispe IN: CD95/Fas signaling in T lymphocytes induces the cell cycle control protein p21cip-1/WAF-1, which promotes apoptosis. J Immunol. 2000 Apr 15. PMID: 10754295

Huang CJ, Favre I, Moczydlowski E: Permeation of large tetra-alkylammonium cations through mutant and wild-type voltage-gated sodium channels as revealed by relief of block at high voltage. J Gen Physiol. 2000 Apr. PMID: 10736311

Mahboubi K, Biedermann BC, Carroll JM, Pober JS: IL-11 activates human endothelial cells to resist immune-mediated injury. J Immunol. 2000 Apr 1. PMID: 10725745

Renganathan M, Cummins TR, Hormuzdiar WN, Black JA, Waxman SG: Nitric oxide is an autocrine regulator of Na(+) currents in axotomized C-type DRG neurons. J Neurophysiol. 2000 Apr. PMID: 10758144

Baccei ML, Kocsis JD: Voltage-gated calcium currents in axotomized adult rat cutaneous afferent neurons. J Neurophysiol. 2000 Apr. PMID: 10758131

Otterbein LE, Bach FH, Alam J, Soares M, Tao Lu H, Wysk M, Davis RJ, Flavell RA, Choi AM: Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat Med. 2000 Apr. PMID: 10742149

Lai CC, Henningson C, DiMaio D: Bovine papillomavirus E5 protein induces the formation of signal transduction complexes containing dimeric activated platelet-derived growth factor beta receptor and associated signaling proteins. J Biol Chem. 2000 Mar 31. PMID: 10734138

Kafitz KW, Leinders-Zufall T, Zufall F, Greer CA: Cyclic GMP evoked calcium transients in olfactory receptor cell growth cones. Neuroreport. 2000 Mar 20. PMID: 10757499

Castner SA, Williams GV, Goldman-Rakic PS: Reversal of antipsychotic-induced working memory deficits by short-term dopamine D1 receptor stimulation. Science. 2000 Mar 17. PMID: 10720329

Yin Z, Zhang DH, Welte T, Bahtiyar G, Jung S, Liu L, Fu XY, Ray A, Craft J: Dominance of IL-12 over IL-4 in gamma delta T cell differentiation leads to default production of IFN-gamma: failure to down-regulate IL-12 receptor beta 2-chain expression. J Immunol. 2000 Mar 15. PMID: 10706694

Smith TC, Wang LY, Howe JR: Heterogeneous conductance levels of native AMPA receptors. J Neurosci. 2000 Mar 15. PMID: 10704481

Chafee MV, Goldman-Rakic PS: Inactivation of parietal and prefrontal cortex reveals interdependence of neural activity during memory-guided saccades. J Neurophysiol. 2000 Mar. PMID: 10712479

Chen WR, Xiong W, Shepherd GM: Analysis of relations between NMDA receptors and GABA release at olfactory bulb reciprocal synapses. Neuron. 2000 Mar. PMID: 10774730

Carlson JR: Insulation of signaling pathways: odor discrimination via olfactosomes? Neuron. 2000 Mar. PMID: 10774717

Favre I, Moss GW, Goldenberg DP, Otlewski J, Moczydlowski E: Structure-activity relationships for the interaction of bovine pancreatic trypsin inhibitor with an intracellular site on a large conductance Ca(2+)-activated K(+) channel. Biochemistry. 2000 Feb 29. PMID: 10684650

Fenwick C, Na SY, Voll RE, Zhong H, Im SY, Lee JW, Ghosh S: A subclass of Ras proteins that regulate the degradation of IkappaB. Science. 2000 Feb 4. PMID: 10657303

Kugaya A, Fujita M, Innis RB: Applications of SPECT imaging of dopaminergic neurotransmission in neuropsychiatric disorders. Ann Nucl Med. 2000 Feb. PMID: 10770574

Gorelik L, Flavell RA: Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease. Immunity. 2000 Feb. PMID: 10714683

Medzhitov R, Janeway C Jr: Innate immune recognition: mechanisms and pathways. Immunol Rev. 2000 Feb. PMID: 10719670

Alreja M, Shanabrough M, Liu W, Leranth C: Opioids suppress IPSCs in neurons of the rat medial septum/diagonal band of Broca: involvement of mu-opioid receptors and septohippocampal GABAergic neurons. J Neurosci. 2000 Feb 1. PMID: 10648722

Halaban R: The regulation of normal melanocyte proliferation. Pigment Cell Res. 2000 Feb. PMID: 10761990

Chen JG, Rudnick G: Permeation and gating residues in serotonin transporter. Proc Natl Acad Sci U S A. 2000 Feb 1. PMID: 10655481

Green EA, Wong FS, Eshima K, Mora C, Flavell RA: Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells. J Exp Med. 2000 Jan 17. PMID: 10637268

LeMosy EK, Hashimoto C: The nudel protease of Drosophila is required for eggshell biogenesis in addition to embryonic patterning. Dev Biol. 2000 Jan 15. PMID: 10625559

Dong C, Flavell RA: Cell fate decision: T-helper 1 and 2 subsets in immune responses. Arthritis Res. 2000; 2000 Mar 27. PMID: 11094427

Stern DF: Tyrosine kinase signalling in breast cancer: ErbB family receptor tyrosine kinases. Breast Cancer Res. 2000; 2000 Mar 25. PMID: 11250707

Basson MD, Emenaker NJ, Sanders MA: Alpha integrin subunits regulate human (Caco-2) intestinal epithelial proliferation and phenotype. Cell Physiol Biochem. 2000. PMID: 10844395

Fujita M, Innis RB: Nuclear psychiatry: specialty for the twenty-first century? Eur J Nucl Med. 2000. PMID: 10744471

Duzgun SA, Rasque H, Kito H, Azuma N, Li W, Basson MD, Gahtan V, Dudrick SJ, Sumpio BE: Mitogen-activated protein phosphorylation in endothelial cells exposed to hyperosmolar conditions. J Cell Biochem. 2000 Jan. PMID: 10653976

Anand A, Charney DS: Norepinephrine dysfunction in depression. J Clin Psychiatry. 2000. PMID: 10910013

Zhang G, Ghosh S: Molecular mechanisms of NF-kappaB activation induced by bacterial lipopolysaccharide through Toll-like receptors. J Endotoxin Res. 2000. PMID: 11521070

Nugent CT, Morgan DJ, Biggs JA, Ko A, Pilip IM, Pamer EG, Sherman LA: Characterization of CD8+ T lymphocytes that persist after peripheral tolerance to a self antigen expressed in the pancreas. J Immunol. 2000 Jan 1. PMID: 10605011

Yan W, Vellucci VF, Reiss M: Smad protein expression and activation in transforming growth factor-beta refractory human squamous cell carcinoma cells. Oncol Res. 2000. PMID: 11216674

Arnsten AF: Stress impairs prefrontal cortical function in rats and monkeys: role of dopamine D1 and norepinephrine alpha-1 receptor mechanisms. Prog Brain Res. 2000. PMID: 11105647

Ashley T: An integration of old and new perspectives of mammalian meiotic sterility. Results Probl Cell Differ. 2000. PMID: 10626297

Forget BG, Degan BA, Arcasoy MO: Familial polycythemia due to truncations of the erythropoietin receptor. Trans Am Clin Climatol Assoc. 2000. PMID: 10881330

Potter CJ, Turenchalk GS, Xu T: Drosophila in cancer research. An expanding role. Trends Genet. 2000 Jan. PMID: 10637629

Feng Y, Chao D, He X, Yang Y, Kang X, H Lazarus L, Xia Y: A novel insight into neuroprotection against hypoxic/ischemic stress. Sheng Li Xue Bao. 2009 Dec 25. PMID: 20029693

Long M, Park SG, Strickland I, Hayden MS, Ghosh S: Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor. Immunity. 2009 Dec 18. PMID: 20064449

Lampert A, Dib-Hajj SD, Eastman EM, Tyrrell L, Lin Z, Yang Y, Waxman SG: Erythromelalgia mutation L823R shifts activation and inactivation of threshold sodium channel Nav1.7 to hyperpolarized potentials. Biochem Biophys Res Commun. 2009 Dec 11; 2009 Oct 1. PMID: 19800314

Fernández-Hernando C, József L, Jenkins D, Di Lorenzo A, Sessa WC: Absence of Akt1 reduces vascular smooth muscle cell migration and survival and induces features of plaque vulnerability and cardiac dysfunction during atherosclerosis. Arterioscler Thromb Vasc Biol. 2009 Dec; 2009 Sep 17. PMID: 19762778

Weatherbee SD, Niswander LA, Anderson KV: A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling. Hum Mol Genet. 2009 Dec 1; 2009 Sep 22. PMID: 19776033

Donnelly DF: Nicotinic acetylcholine receptors do not mediate excitatory transmission in young rat carotid body. J Appl Physiol (1985). 2009 Dec; 2009 Sep 17. PMID: 19762524

Roth RJ, Le AM, Zhang L, Kahn M, Samuel VT, Shulman GI, Bennett AM: MAPK phosphatase-1 facilitates the loss of oxidative myofibers associated with obesity in mice. J Clin Invest. 2009 Dec; 2009 Nov 16. PMID: 19920356

Qi D, Hu X, Wu X, Merk M, Leng L, Bucala R, Young LH: Cardiac macrophage migration inhibitory factor inhibits JNK pathway activation and injury during ischemia/reperfusion. J Clin Invest. 2009 Dec; 2009 Nov 16. PMID: 19920350

Jha MK, Badou A, Meissner M, McRory JE, Freichel M, Flockerzi V, Flavell RA: Defective survival of naive CD8+ T lymphocytes in the absence of the beta3 regulatory subunit of voltage-gated calcium channels. Nat Immunol. 2009 Dec; 2009 Oct 18. PMID: 19838200

Smith KD, Lipchock SV, Ames TD, Wang J, Breaker RR, Strobel SA: Structural basis of ligand binding by a c-di-GMP riboswitch. Nat Struct Mol Biol. 2009 Dec; 2009 Nov 8. PMID: 19898477

Swan L: An unnatural PIP simulates growth factor signaling. Chem Biol. 2009 Nov 25. PMID: 19942133

Izmaylov AF, Tully JC, Frisch MJ: Relativistic interactions in the radical pair model of magnetic field sense in CRY-1 protein of Arabidopsis thaliana. J Phys Chem A. 2009 Nov 5. PMID: 19863135

Li Q, Liu J, Michaud M, Schwartz ML, Madri JA: Strain differences in behavioral and cellular responses to perinatal hypoxia and relationships to neural stem cell survival and self-renewal: Modeling the neurovascular niche. Am J Pathol. 2009 Nov; 2009 Oct 8. PMID: 19815710

Casuscelli J, Schmidt S, DeGray B, Petri ET, Celić A, Folta-Stogniew E, Ehrlich BE, Boggon TJ: Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2. Am J Physiol Renal Physiol. 2009 Nov; 2009 Sep 2. PMID: 19726544

Drozdov I, Kidd M, Gustafsson BI, Svejda B, Joseph R, Pfragner R, Modlin IM: Autoregulatory effects of serotonin on proliferation and signaling pathways in lung and small intestine neuroendocrine tumor cell lines. Cancer. 2009 Nov 1. PMID: 19634160

Gorelick FS, Thrower E: The acinar cell and early pancreatitis responses. Clin Gastroenterol Hepatol. 2009 Nov. PMID: 19896090

Dietrich MO, Horvath TL: Feeding signals and brain circuitry. Eur J Neurosci. 2009 Nov; 2009 Oct 28. PMID: 19878280

Weerachayaphorn J, Cai SY, Soroka CJ, Boyer JL: Nuclear factor erythroid 2-related factor 2 is a positive regulator of human bile salt export pump expression. Hepatology. 2009 Nov. PMID: 19821532

Kundel M, Jones KJ, Shin CY, Wells DG: Cytoplasmic polyadenylation element-binding protein regulates neurotrophin-3-dependent beta-catenin mRNA translation in developing hippocampal neurons. J Neurosci. 2009 Oct 28. PMID: 19864575

Guo X, Nie L, Esmailzadeh L, Zhang J, Bender JR, Sadeghi MM: Endothelial and smooth muscle-derived neuropilin-like protein regulates platelet-derived growth factor signaling in human vascular smooth muscle cells by modulating receptor ubiquitination. J Biol Chem. 2009 Oct 23; 2009 Aug 19. PMID: 19696027

Hains AB, Vu MA, Maciejewski PK, van Dyck CH, Gottron M, Arnsten AF: Inhibition of protein kinase C signaling protects prefrontal cortex dendritic spines and cognition from the effects of chronic stress. Proc Natl Acad Sci U S A. 2009 Oct 20; 2009 Sep 11. PMID: 19805148

Griffith JW, Sun T, McIntosh MT, Bucala R: Pure Hemozoin is inflammatory in vivo and activates the NALP3 inflammasome via release of uric acid. J Immunol. 2009 Oct 15; 2009 Sep 25. PMID: 19783673

Krystal JH, Neumeister A: Noradrenergic and serotonergic mechanisms in the neurobiology of posttraumatic stress disorder and resilience. Brain Res. 2009 Oct 13; 2009 Mar 28. PMID: 19332037

Choy JC, Pober JS: Generation of NO by bystander human CD8 T cells augments allogeneic responses by inhibiting cytokine deprivation-induced cell death. Am J Transplant. 2009 Oct; 2009 Aug 6. PMID: 19663890

Blachford C, Celić A, Petri ET, Ehrlich BE: Discrete proteolysis of neuronal calcium sensor-1 (NCS-1) by mu-calpain disrupts calcium binding. Cell Calcium. 2009 Oct; 2009 Sep 3. PMID: 19732951

Oeckinghaus A, Ghosh S: The NF-kappaB family of transcription factors and its regulation. Cold Spring Harb Perspect Biol. 2009 Oct. PMID: 20066092

Bradley WD, Koleske AJ: Regulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contexts. J Cell Sci. 2009 Oct 1. PMID: 19759284

Sanacora G: Do glutamatergic agents represent a new class of antidepressant drugs? Part 1. J Clin Psychiatry. 2009 Oct. PMID: 19906350

Mason AB, Hoh J: CCR3: Shedding new light on a dark problem? J Mol Cell Biol. 2009 Oct; 2009 Aug 14. PMID: 19684049

Tan AM, Choi JS, Waxman SG, Hains BC: Dendritic spine remodeling after spinal cord injury alters neuronal signal processing. J Neurophysiol. 2009 Oct; 2009 Aug 19. PMID: 19692517

Medzhitov R, Horng T: Transcriptional control of the inflammatory response. Nat Rev Immunol. 2009 Oct. PMID: 19859064

Greene J, Banasr M, Lee B, Warner-Schmidt J, Duman RS: Vascular endothelial growth factor signaling is required for the behavioral actions of antidepressant treatment: pharmacological and cellular characterization. Neuropsychopharmacology. 2009 Oct; 2009 Jun 24. PMID: 19553916

Dib-Hajj SD, Black JA, Waxman SG: Voltage-gated sodium channels: therapeutic targets for pain. Pain Med. 2009 Oct. PMID: 19818036

Soulsby M, Bennett AM: Physiological signaling specificity by protein tyrosine phosphatases. Physiology (Bethesda). 2009 Oct. PMID: 19815854

Bai F, Town T, Qian F, Wang P, Kamanaka M, Connolly TM, Gate D, Montgomery RR, Flavell RA, Fikrig E: IL-10 signaling blockade controls murine West Nile virus infection. PLoS Pathog. 2009 Oct; 2009 Oct 9. PMID: 19816558

Stark R, Pasquel F, Turcu A, Pongratz RL, Roden M, Cline GW, Shulman GI, Kibbey RG: Phosphoenolpyruvate cycling via mitochondrial phosphoenolpyruvate carboxykinase links anaplerosis and mitochondrial GTP with insulin secretion. J Biol Chem. 2009 Sep 25; 2009 Jul 27. PMID: 19635791

Kim KH, Bender JR: Membrane-initiated actions of estrogen on the endothelium. Mol Cell Endocrinol. 2009 Sep 24; 2009 Apr 9. PMID: 19549586

Torii M, Hashimoto-Torii K, Levitt P, Rakic P: Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. Nature. 2009 Sep 24; 2009 Sep 16. PMID: 19759535

Wang L, Sigworth FJ: Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy. Nature. 2009 Sep 10; 2009 Aug 30. PMID: 19718020

Li JH, D'Alessio A, Pober JS: Lipopolysaccharide can trigger a cathepsin B-dependent programmed death response in human endothelial cells. Am J Pathol. 2009 Sep; 2009 Aug 6. PMID: 19661440

Gerber SA, Yatsula B, Maier CL, Sadler TJ, Whittaker LW, Pober JS: Interferon-gamma induces prolyl hydroxylase (PHD)3 through a STAT1-dependent mechanism in human endothelial cells. Arterioscler Thromb Vasc Biol. 2009 Sep; 2009 Jul 2. PMID: 19574556

Husain S, Thrower E: Molecular and cellular regulation of pancreatic acinar cell function. Curr Opin Gastroenterol. 2009 Sep. PMID: 19571746

Jülich D, Mould AP, Koper E, Holley SA: Control of extracellular matrix assembly along tissue boundaries via Integrin and Eph/Ephrin signaling. Development. 2009 Sep; 2009 Jul 29. PMID: 19641014

Matza D, Flavell RA: Roles of Ca(v) channels and AHNAK1 in T cells: the beauty and the beast. Immunol Rev. 2009 Sep. PMID: 19754902

Du F, Galán JE: Selective inhibition of type III secretion activated signaling by the Salmonella effector AvrA. PLoS Pathog. 2009 Sep; 2009 Sep 25. PMID: 19779561

Huang K, Diener DR, Rosenbaum JL: The ubiquitin conjugation system is involved in the disassembly of cilia and flagella. J Cell Biol. 2009 Aug 24. PMID: 19704024

Amankulor NM, Hambardzumyan D, Pyonteck SM, Becher OJ, Joyce JA, Holland EC: Sonic hedgehog pathway activation is induced by acute brain injury and regulated by injury-related inflammation. J Neurosci. 2009 Aug 19. PMID: 19692604

Chen H, Ko G, Zatti A, Di Giacomo G, Liu L, Raiteri E, Perucco E, Collesi C, Min W, Zeiss C, De Camilli P, Cremona O: Embryonic arrest at midgestation and disruption of Notch signaling produced by the absence of both epsin 1 and epsin 2 in mice. Proc Natl Acad Sci U S A. 2009 Aug 18; 2009 Aug 5. PMID: 19666558

Margulies D, Opatowsky Y, Fletcher S, Saraogi I, Tsou LK, Saha S, Lax I, Schlessinger J, Hamilton AD: Surface binding inhibitors of the SCF-KIT protein-protein interaction. Chembiochem. 2009 Aug 17. PMID: 19637142

Vaccarino FM, Smith KM: Increased brain size in autism--what it will take to solve a mystery. Biol Psychiatry. 2009 Aug 15. PMID: 19643218

Tanis JE, Bellemer A, Moresco JJ, Forbush B, Koelle MR: The potassium chloride cotransporter KCC-2 coordinates development of inhibitory neurotransmission and synapse structure in Caenorhabditis elegans. J Neurosci. 2009 Aug 12. PMID: 19675228

Bae JH, Lew ED, Yuzawa S, Tomé F, Lax I, Schlessinger J: The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site. Cell. 2009 Aug 7. PMID: 19665973

Schleicher M, Yu J, Murata T, Derakhshan B, Atochin D, Qian L, Kashiwagi S, Di Lorenzo A, Harrison KD, Huang PL, Sessa WC: The Akt1-eNOS axis illustrates the specificity of kinase-substrate relationships in vivo. Sci Signal. 2009 Aug 4; 2009 Aug 4. PMID: 19654415

Zhang XF, Forscher P: Rac1 modulates stimulus-evoked Ca(2+) release in neuronal growth cones via parallel effects on microtubule/endoplasmic reticulum dynamics and reactive oxygen species production. Mol Biol Cell. 2009 Aug; 2009 Jul 1. PMID: 19570918

Tiwari S, Choi HP, Matsuzawa T, Pypaert M, MacMicking JD: Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P(2) and PtdIns(3,4,5)P(3) promotes immunity to mycobacteria. Nat Immunol. 2009 Aug. PMID: 19620982

Bruno VM, Hannemann S, Lara-Tejero M, Flavell RA, Kleinstein SH, Galán JE: Salmonella Typhimurium type III secretion effectors stimulate innate immune responses in cultured epithelial cells. PLoS Pathog. 2009 Aug; 2009 Aug 7. PMID: 19662166

Alexander RP, Kim PM, Emonet T, Gerstein MB: Understanding modularity in molecular networks requires dynamics. Sci Signal. 2009 Jul 28; 2009 Jul 28. PMID: 19638611

Sanjabi S, Mosaheb MM, Flavell RA: Opposing effects of TGF-beta and IL-15 cytokines control the number of short-lived effector CD8+ T cells. Immunity. 2009 Jul 17. PMID: 19604492

Sinha R: Stress and addiction: a dynamic interplay of genes, environment, and drug intake. Biol Psychiatry. 2009 Jul 15. PMID: 19555787

Alvero AB, Montagna MK, Chen R, Kim KH, Kyungjin K, Visintin I, Fu HH, Brown D, Mor G: NV-128, a novel isoflavone derivative, induces caspase-independent cell death through the Akt/mammalian target of rapamycin pathway. Cancer. 2009 Jul 15. PMID: 19472400

Simons M: Diabetic monocyte and vascular endothelial growth factor signaling impairment. Circulation. 2009 Jul 14; 2009 Jun 29. PMID: 19564554

de Araujo IE: Gustatory and homeostatic functions of the rodent parabrachial nucleus. Ann N Y Acad Sci. 2009 Jul. PMID: 19686163

Tal MC, Iwasaki A: Autophagic control of RLR signaling. Autophagy. 2009 Jul. PMID: 19571662

Kidd M, Hauso Ø, Drozdov I, Gustafsson BI, Modlin IM: Delineation of the chemomechanosensory regulation of gastrin secretion using pure rodent G cells. Gastroenterology. 2009 Jul; 2009 Jan 14. PMID: 19208342

Ip WK, Takahashi K, Ezekowitz RA, Stuart LM: Mannose-binding lectin and innate immunity. Immunol Rev. 2009 Jul. PMID: 19594626

Abraham C, Cho J: Interleukin-23/Th17 pathways and inflammatory bowel disease. Inflamm Bowel Dis. 2009 Jul. PMID: 19253307

Nakajima A, Sanjay A, Chiusaroli R, Adapala NS, Neff L, Itzsteink C, Horne WC, Baron R: Loss of Cbl-b increases osteoclast bone-resorbing activity and induces osteopenia. J Bone Miner Res. 2009 Jul. PMID: 19257814

Brunzell DH, Mineur YS, Neve RL, Picciotto MR: Nucleus accumbens CREB activity is necessary for nicotine conditioned place preference. Neuropsychopharmacology. 2009 Jul; 2009 Feb 11. PMID: 19212318

Panda A, Arjona A, Sapey E, Bai F, Fikrig E, Montgomery RR, Lord JM, Shaw AC: Human innate immunosenescence: causes and consequences for immunity in old age. Trends Immunol. 2009 Jul; 2009 Jun 21. PMID: 19541535

Matza D, Badou A, Jha MK, Willinger T, Antov A, Sanjabi S, Kobayashi KS, Marchesi VT, Flavell RA: Requirement for AHNAK1-mediated calcium signaling during T lymphocyte cytolysis. Proc Natl Acad Sci U S A. 2009 Jun 16; 2009 Jun 2. PMID: 19497879

Daw NW: The foundations of development and deprivation in the visual system. J Physiol. 2009 Jun 15; 2009 Feb 16. PMID: 19221122

Watanabe A, Sohail MA, Gomes DA, Hashmi A, Nagata J, Sutterwala FS, Mahmood S, Jhandier MN, Shi Y, Flavell RA, Mehal WZ: Inflammasome-mediated regulation of hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol. 2009 Jun; 2009 Apr 9. PMID: 19359429

Cakmak H, Guzeloglu-Kayisli O, Kayisli UA, Arici A: Immune-endocrine interactions in endometriosis. Front Biosci (Elite Ed). 2009 Jun 1; 2009 Jun 1. PMID: 19482657

Horsley V: Epigenetics, Wnt signaling, and stem cells: the Pygo2 connection. J Cell Biol. 2009 Jun 1. PMID: 19487452

Snellman J, Zenisek D, Nawy S: Switching between transient and sustained signalling at the rod bipolar-AII amacrine cell synapse of the mouse retina. J Physiol. 2009 Jun 1; 2009 Mar 30. PMID: 19332496

Arnsten AF: Stress signalling pathways that impair prefrontal cortex structure and function. Nat Rev Neurosci. 2009 Jun. PMID: 19455173

Young SZ, Bordey A: GABA's control of stem and cancer cell proliferation in adult neural and peripheral niches. Physiology (Bethesda). 2009 Jun. PMID: 19509127

Nogueira CV, Lindsten T, Jamieson AM, Case CL, Shin S, Thompson CB, Roy CR: Rapid pathogen-induced apoptosis: a mechanism used by dendritic cells to limit intracellular replication of Legionella pneumophila. PLoS Pathog. 2009 Jun; 2009 Jun 12. PMID: 19521510

Marks BR, Craft J: Barrier immunity and IL-17. Semin Immunol. 2009 Jun; 2009 Apr 21. PMID: 19386512

Orme CM, Bogan JS: Cell biology. Sorting out diabetes. Science. 2009 May 29. PMID: 19478173

Stabach PR, Simonović I, Ranieri MA, Aboodi MS, Steitz TA, Simonović M, Morrow JS: The structure of the ankyrin-binding site of beta-spectrin reveals how tandem spectrin-repeats generate unique ligand-binding properties. Blood. 2009 May 28; 2009 Jan 23. PMID: 19168783

Yu L, Min W, He Y, Qin L, Zhang H, Bennett AM, Chen H: JAK2 and SHP2 reciprocally regulate tyrosine phosphorylation and stability of proapoptotic protein ASK1. J Biol Chem. 2009 May 15; 2009 Mar 13. PMID: 19287004

Kim AS, Miller EJ, Young LH: AMP-activated protein kinase: a core signalling pathway in the heart. Acta Physiol (Oxf). 2009 May; 2009 Feb 23. PMID: 19239414

Kim Y, Lin Q, Glazer PM, Yun Z: Hypoxic tumor microenvironment and cancer cell differentiation. Curr Mol Med. 2009 May. PMID: 19519400

Page KA, Williamson A, Yu N, McNay EC, Dzuira J, McCrimmon RJ, Sherwin RS: Medium-chain fatty acids improve cognitive function in intensively treated type 1 diabetic patients and support in vitro synaptic transmission during acute hypoglycemia. Diabetes. 2009 May; 2009 Feb 17. PMID: 19223595

Dave KA, Bordey A: GABA increases Ca2+ in cerebellar granule cell precursors via depolarization: implications for proliferation. IUBMB Life. 2009 May. PMID: 19391160

Brodsky IE, Medzhitov R: Targeting of immune signalling networks by bacterial pathogens. Nat Cell Biol. 2009 May. PMID: 19404331

Huang J, Huen MS, Kim H, Leung CC, Glover JN, Yu X, Chen J: RAD18 transmits DNA damage signalling to elicit homologous recombination repair. Nat Cell Biol. 2009 May; 2009 Apr 26. PMID: 19396164

Zenewicz LA, Antov A, Flavell RA: CD4 T-cell differentiation and inflammatory bowel disease. Trends Mol Med. 2009 May; 2009 Apr 8. PMID: 19362058

Rivera M, Muto A, Feigel A, Kondo Y, Dardik A: Venous and arterial identity: a role for caveolae? Vascular. 2009 May-Jun. PMID: 19426603

Mulla MJ, Yu AG, Cardenas I, Guller S, Panda B, Abrahams VM: Regulation of Nod1 and Nod2 in first trimester trophoblast cells. Am J Reprod Immunol. 2009 Apr. PMID: 19260860

Dai S, He Y, Zhang H, Yu L, Wan T, Xu Z, Jones D, Chen H, Min W: Endothelial-specific expression of mitochondrial thioredoxin promotes ischemia-mediated arteriogenesis and angiogenesis. Arterioscler Thromb Vasc Biol. 2009 Apr; 2009 Jan 15. PMID: 19150880

Dib-Hajj SD, Binshtok AM, Cummins TR, Jarvis MF, Samad T, Zimmermann K: Voltage-gated sodium channels in pain states: role in pathophysiology and targets for treatment. Brain Res Rev. 2009 Apr; 2008 Dec 25. PMID: 19150627

Basu B, Brueckner M: Fibroblast "cilia growth" factor in the development of left-right asymmetry. Dev Cell. 2009 Apr. PMID: 19386257

Wen H, Blume PA, Sumpio BE: Role of integrins and focal adhesion kinase in the orientation of dermal fibroblasts exposed to cyclic strain. Int Wound J. 2009 Apr. PMID: 19432665

Koga K, Aldo PB, Mor G: Toll-like receptors and pregnancy: trophoblast as modulators of the immune response. J Obstet Gynaecol Res. 2009 Apr. PMID: 19335792

Wu M, Dumalska I, Morozova E, van den Pol AN, Alreja M: Gonadotropin inhibitory hormone inhibits basal forebrain vGluT2-gonadotropin-releasing hormone neurons via a direct postsynaptic mechanism. J Physiol. 2009 Apr 1; 2009 Feb 9. PMID: 19204051

Fitzpatrick JS, Hagenston AM, Hertle DN, Gipson KE, Bertetto-D'Angelo L, Yeckel MF: Inositol-1,4,5-trisphosphate receptor-mediated Ca2+ waves in pyramidal neuron dendrites propagate through hot spots and cold spots. J Physiol. 2009 Apr 1; 2009 Feb 9. PMID: 19204047

Maddika S, Chen J: Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase. Nat Cell Biol. 2009 Apr; 2009 Mar 15. PMID: 19287380

Bezbradica JS, Medzhitov R: Integration of cytokine and heterologous receptor signaling pathways. Nat Immunol. 2009 Apr; 2009 Mar 19. PMID: 19295629

Kidd M, Gustafsson BI, Drozdov I, Modlin IM: IL1beta- and LPS-induced serotonin secretion is increased in EC cells derived from Crohn's disease. Neurogastroenterol Motil. 2009 Apr; 2008 Oct 25. PMID: 19019013

Palm NW, Medzhitov R: Immunostimulatory activity of haptenated proteins. Proc Natl Acad Sci U S A. 2009 Mar 24; 2009 Mar 2. PMID: 19255434

Zoncu R, Perera RM, Balkin DM, Pirruccello M, Toomre D, De Camilli P: A phosphoinositide switch controls the maturation and signaling properties of APPL endosomes. Cell. 2009 Mar 20. PMID: 19303853

Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G: Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation. 2009 Mar 17; 2009 Mar 2. PMID: 19255340

Gresack JE, Schafe GE, Orr PT, Frick KM: Sex differences in contextual fear conditioning are associated with differential ventral hippocampal extracellular signal-regulated kinase activation. Neuroscience. 2009 Mar 17; 2009 Jan 10. PMID: 19171181

Da Silva CA, Chalouni C, Williams A, Hartl D, Lee CG, Elias JA: Chitin is a size-dependent regulator of macrophage TNF and IL-10 production. J Immunol. 2009 Mar 15. PMID: 19265136

Yu J, Sheung N, Soliman EM, Spirli C, Dranoff JA: Transcriptional regulation of IL-6 in bile duct epithelia by extracellular ATP. Am J Physiol Gastrointest Liver Physiol. 2009 Mar; 2009 Jan 8. PMID: 19136380

Soliman EM, Rodrigues MA, Gomes DA, Sheung N, Yu J, Amaya MJ, Nathanson MH, Dranoff JA: Intracellular calcium signals regulate growth of hepatic stellate cells via specific effects on cell cycle progression. Cell Calcium. 2009 Mar; 2009 Jan 7. PMID: 19131107

Chao D, Balboni G, Lazarus LH, Salvadori S, Xia Y: Na+ mechanism of delta-opioid receptor induced protection from anoxic K+ leakage in the cortex. Cell Mol Life Sci. 2009 Mar. PMID: 19189047

Igaki T, Pastor-Pareja JC, Aonuma H, Miura M, Xu T: Intrinsic tumor suppression and epithelial maintenance by endocytic activation of Eiger/TNF signaling in Drosophila. Dev Cell. 2009 Mar. PMID: 19289090

Homma R, Cohen LB, Kosmidis EK, Youngentob SL: Perceptual stability during dramatic changes in olfactory bulb activation maps and dramatic declines in activation amplitudes. Eur J Neurosci. 2009 Mar. PMID: 19291227

Ceserani T, Trofka A, Gandotra N, Nelson T: VH1/BRL2 receptor-like kinase interacts with vascular-specific adaptor proteins VIT and VIK to influence leaf venation. Plant J. 2009 Mar; 2008 Nov 3. PMID: 19000166

Tal MC, Sasai M, Lee HK, Yordy B, Shadel GS, Iwasaki A: Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling. Proc Natl Acad Sci U S A. 2009 Feb 24; 2009 Feb 5. PMID: 19196953

Town T, Bai F, Wang T, Kaplan AT, Qian F, Montgomery RR, Anderson JF, Flavell RA, Fikrig E: Toll-like receptor 7 mitigates lethal West Nile encephalitis via interleukin 23-dependent immune cell infiltration and homing. Immunity. 2009 Feb 20; 2009 Feb 5. PMID: 19200759

DiBella LM, Park A, Sun Z: Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathway. Hum Mol Genet. 2009 Feb 15; 2008 Nov 13. PMID: 19008302

Li T, Yang Y, Canessa CM: Interaction of the aromatics Tyr-72/Trp-288 in the interface of the extracellular and transmembrane domains is essential for proton gating of acid-sensing ion channels. J Biol Chem. 2009 Feb 13; 2008 Dec 11. PMID: 19074149

Zhang W, St-Gelais F, Grabner CP, Trinidad JC, Sumioka A, Morimoto-Tomita M, Kim KS, Straub C, Burlingame AL, Howe JR, Tomita S: A transmembrane accessory subunit that modulates kainate-type glutamate receptors. Neuron. 2009 Feb 12. PMID: 19217376

Pluznick JL, Zou DJ, Zhang X, Yan Q, Rodriguez-Gil DJ, Eisner C, Wells E, Greer CA, Wang T, Firestein S, Schnermann J, Caplan MJ: Functional expression of the olfactory signaling system in the kidney. Proc Natl Acad Sci U S A. 2009 Feb 10; 2009 Jan 27. PMID: 19174512

Pawlicki JM, Steitz JA: Subnuclear compartmentalization of transiently expressed polyadenylated pri-microRNAs: processing at transcription sites or accumulation in SC35 foci. Cell Cycle. 2009 Feb 1; 2009 Feb 21. PMID: 19177009

Imaeda AB, Watanabe A, Sohail MA, Mahmood S, Mohamadnejad M, Sutterwala FS, Flavell RA, Mehal WZ: Acetaminophen-induced hepatotoxicity in mice is dependent on Tlr9 and the Nalp3 inflammasome. J Clin Invest. 2009 Feb; 2009 Jan 26. PMID: 19164858

Park SG, Schulze-Luehrman J, Hayden MS, Hashimoto N, Ogawa W, Kasuga M, Ghosh S: The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-kappaB and activate T cells. Nat Immunol. 2009 Feb; 2009 Jan 4. PMID: 19122654

Gangaraju VK, Lin H: MicroRNAs: key regulators of stem cells. Nat Rev Mol Cell Biol. 2009 Feb. PMID: 19165214

Shen Y, Zhou Z, Feng S, Li J, Tan-Wilson A, Qu LJ, Wang H, Deng XW: Phytochrome A mediates rapid red light-induced phosphorylation of Arabidopsis FAR-RED ELONGATED HYPOCOTYL1 in a low fluence response. Plant Cell. 2009 Feb; 2009 Feb 10. PMID: 19208901

Pan Y, Shadel GS: Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density. Aging (Albany NY). 2009 Jan 28; 2009 Jan 28. PMID: 20157595

Khurana E, Dal Peraro M, DeVane R, Vemparala S, DeGrado WF, Klein ML: Molecular dynamics calculations suggest a conduction mechanism for the M2 proton channel from influenza A virus. Proc Natl Acad Sci U S A. 2009 Jan 27; 2009 Jan 14. PMID: 19144924

Harburger DS, Calderwood DA: Integrin signalling at a glance. J Cell Sci. 2009 Jan 15. PMID: 19118207

Morimoto-Tomita M, Zhang W, Straub C, Cho CH, Kim KS, Howe JR, Tomita S: Autoinactivation of neuronal AMPA receptors via glutamate-regulated TARP interaction. Neuron. 2009 Jan 15. PMID: 19146816

Acosta IF, Laparra H, Romero SP, Schmelz E, Hamberg M, Mottinger JP, Moreno MA, Dellaporta SL: tasselseed1 is a lipoxygenase affecting jasmonic acid signaling in sex determination of maize. Science. 2009 Jan 9. PMID: 19131630

Pober JS, Min W, Bradley JR: Mechanisms of endothelial dysfunction, injury, and death. Annu Rev Pathol. 2009. PMID: 18754744

Archer KA, Alexopoulou L, Flavell RA, Roy CR: Multiple MyD88-dependent responses contribute to pulmonary clearance of Legionella pneumophila. Cell Microbiol. 2009 Jan; 2008 Sep 8. PMID: 18782351

Ishibe S, Karihaloo A, Ma H, Zhang J, Marlier A, Mitobe M, Togawa A, Schmitt R, Czyczk J, Kashgarian M, Geller DS, Thorgeirsson SS, Cantley LG: Met and the epidermal growth factor receptor act cooperatively to regulate final nephron number and maintain collecting duct morphology. Development. 2009 Jan. PMID: 19103805

Duman RS: Neuronal damage and protection in the pathophysiology and treatment of psychiatric illness: stress and depression. Dialogues Clin Neurosci. 2009. PMID: 19877493

Sohail MA, Hashmi AZ, Hakim W, Watanabe A, Zipprich A, Groszmann RJ, Dranoff JA, Torok NJ, Mehal WZ: Adenosine induces loss of actin stress fibers and inhibits contraction in hepatic stellate cells via Rho inhibition. Hepatology. 2009 Jan. PMID: 18844235

Frick KM: Estrogens and age-related memory decline in rodents: what have we learned and where do we go from here? Horm Behav. 2009 Jan; 2008 Sep 16. PMID: 18835561

Becker SM, Delamarre L, Mellman I, Andrews NW: Differential role of the Ca(2+) sensor synaptotagmin VII in macrophages and dendritic cells. Immunobiology. 2009; 2009 Jan 20. PMID: 19157638

Palm NW, Medzhitov R: Pattern recognition receptors and control of adaptive immunity. Immunol Rev. 2009 Jan. PMID: 19120487

Lombroso P, Ogren M: Learning and memory, part II: molecular mechanisms of synaptic plasticity. J Am Acad Child Adolesc Psychiatry. 2009 Jan. PMID: 19096295

Fleming MR, Kaczmarek LK: Use of optical biosensors to detect modulation of Slack potassium channels by G protein-coupled receptors. J Recept Signal Transduct Res. 2009. PMID: 19640220

Rakoff-Nahoum S, Medzhitov R: Toll-like receptors and cancer. Nat Rev Cancer. 2009 Jan; 2008 Dec 4. PMID: 19052556

Saxe JP, Tomilin A, Schöler HR, Plath K, Huang J: Post-translational regulation of Oct4 transcriptional activity. PLoS One. 2009; 2009 Feb 16. PMID: 19221599

Porter MY, Koelle MR: Insights into RGS protein function from studies in Caenorhabditis elegans. Prog Mol Biol Transl Sci. 2009; 2009 Oct 7. PMID: 20374712

Arnsten AF: Ameliorating prefrontal cortical dysfunction in mental illness: inhibition of phosphotidyl inositol-protein kinase C signaling. Psychopharmacology (Berl). 2009 Jan; 2008 Aug 22. PMID: 18719894

Huebner EA, Strittmatter SM: Axon regeneration in the peripheral and central nervous systems. Results Probl Cell Differ. 2009. PMID: 19582408

Tirziu D, Simons M: Endothelium as master regulator of organ development and growth. Vascul Pharmacol. 2009 Jan-Feb; 2008 Sep 5. PMID: 18804188

Tan AM, Stamboulian S, Chang YW, Zhao P, Hains AB, Waxman SG, Hains BC: Neuropathic pain memory is maintained by Rac1-regulated dendritic spine remodeling after spinal cord injury. J Neurosci. 2008 Dec 3. PMID: 19052208

Lee CG, Hartl D, Matsuura H, Dunlop FM, Scotney PD, Fabri LJ, Nash AD, Chen NY, Tang CY, Chen Q, Homer RJ, Baca M, Elias JA: Endogenous IL-11 signaling is essential in Th2- and IL-13-induced inflammation and mucus production. Am J Respir Cell Mol Biol. 2008 Dec; 2008 Jul 10. PMID: 18617680

Gourley SL, Wu FJ, Taylor JR: Corticosterone regulates pERK1/2 map kinase in a chronic depression model. Ann N Y Acad Sci. 2008 Dec. PMID: 19120149

Zenewicz LA, Flavell RA: IL-22 and inflammation: leukin' through a glass onion. Eur J Immunol. 2008 Dec. PMID: 19016525

Zhang H, He Y, Dai S, Xu Z, Luo Y, Wan T, Luo D, Jones D, Tang S, Chen H, Sessa WC, Min W: AIP1 functions as an endogenous inhibitor of VEGFR2-mediated signaling and inflammatory angiogenesis in mice. J Clin Invest. 2008 Dec; 2008 Nov 3. PMID: 19033661

Zhang W, Howe JR, Popescu GK: Distinct gating modes determine the biphasic relaxation of NMDA receptor currents. Nat Neurosci. 2008 Dec; 2008 Oct 26. PMID: 18953348

Gong LW, De Camilli P: Regulation of postsynaptic AMPA responses by synaptojanin 1. Proc Natl Acad Sci U S A. 2008 Nov 11; 2008 Nov 5. PMID: 18987319

Lou X, Paradise S, Ferguson SM, De Camilli P: Selective saturation of slow endocytosis at a giant glutamatergic central synapse lacking dynamin 1. Proc Natl Acad Sci U S A. 2008 Nov 11; 2008 Nov 5. PMID: 18987309

Lee AS, Duman RS, Pittenger C: A double dissociation revealing bidirectional competition between striatum and hippocampus during learning. Proc Natl Acad Sci U S A. 2008 Nov 4; 2008 Oct 27. PMID: 18955704

Zhong W: Going nuclear is again a winning (Wnt) strategy. Dev Cell. 2008 Nov. PMID: 19000826

Rodrigues MA, Gomes DA, Andrade VA, Leite MF, Nathanson MH: Insulin induces calcium signals in the nucleus of rat hepatocytes. Hepatology. 2008 Nov. PMID: 18798337

Akhtar S, Podgoreanu M, Harrison BA, Brull SJ: Effect of lidocaine on endothelin-1-mediated airway smooth muscle contraction in the rat trachea. Minerva Anestesiol. 2008 Nov. PMID: 18971893

Ghosh S, Hayden MS: New regulators of NF-kappaB in inflammation. Nat Rev Immunol. 2008 Nov. PMID: 18927578

Shin S, Case CL, Archer KA, Nogueira CV, Kobayashi KS, Flavell RA, Roy CR, Zamboni DS: Type IV secretion-dependent activation of host MAP kinases induces an increased proinflammatory cytokine response to Legionella pneumophila. PLoS Pathog. 2008 Nov; 2008 Nov 28. PMID: 19043549

Tirziu D, Simons M: Endothelium-driven myocardial growth or nitric oxide at the crossroads. Trends Cardiovasc Med. 2008 Nov. PMID: 19345317

Idone V, Tam C, Andrews NW: Two-way traffic on the road to plasma membrane repair. Trends Cell Biol. 2008 Nov; 2008 Oct 9. PMID: 18848451

Hashimoto-Torii K, Torii M, Sarkisian MR, Bartley CM, Shen J, Radtke F, Gridley T, Sestan N, Rakic P: Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex. Neuron. 2008 Oct 23. PMID: 18957219

Wang XJ: Decision making in recurrent neuronal circuits. Neuron. 2008 Oct 23. PMID: 18957215

Lal M, Song X, Pluznick JL, Di Giovanni V, Merrick DM, Rosenblum ND, Chauvet V, Gottardi CJ, Pei Y, Caplan MJ: Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling. Hum Mol Genet. 2008 Oct 15; 2008 Jul 16. PMID: 18632682

Geng L, Boehmerle W, Maeda Y, Okuhara DY, Tian X, Yu Z, Choe CU, Anyatonwu GI, Ehrlich BE, Somlo S: Syntaxin 5 regulates the endoplasmic reticulum channel-release properties of polycystin-2. Proc Natl Acad Sci U S A. 2008 Oct 14; 2008 Oct 3. PMID: 18836075

Ota KT, Pierre VJ, Ploski JE, Queen K, Schafe GE: The NO-cGMP-PKG signaling pathway regulates synaptic plasticity and fear memory consolidation in the lateral amygdala via activation of ERK/MAP kinase. Learn Mem. 2008 Oct; 2008 Oct 2. PMID: 18832566

Zhong W: Timing cell-fate determination during asymmetric cell divisions. Curr Opin Neurobiol. 2008 Oct; 2008 Nov 12. PMID: 18983918

Schmidt HD, Banasr M, Duman RS: Future Antidepressant Targets: Neurotrophic Factors and Related Signaling Cascades. Drug Discov Today Ther Strateg. 2008 Fall. PMID: 19802372

Qiao W, Fan LM: Nitric oxide signaling in plant responses to abiotic stresses. J Integr Plant Biol. 2008 Oct. PMID: 19017111

Huen MS, Huang J, Yuan J, Yamamoto M, Akira S, Ashley C, Xiao W, Chen J: Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly. Mol Cell Biol. 2008 Oct; 2008 Aug 4. PMID: 18678647

Kim KH, Moriarty K, Bender JR: Vascular cell signaling by membrane estrogen receptors. Steroids. 2008 Oct; 2008 Jan 18. PMID: 18325557

Zhao P, Barr TP, Hou Q, Dib-Hajj SD, Black JA, Albrecht PJ, Petersen K, Eisenberg E, Wymer JP, Rice FL, Waxman SG: Voltage-gated sodium channel expression in rat and human epidermal keratinocytes: evidence for a role in pain. Pain. 2008 Sep 30; 2008 Apr 28. PMID: 18442883

Huang ST, Lee Y, Gullen EA, Cheng YC: Impacts of baicalein analogs with modification of the 6th position of A ring on the activity toward NF-kappaB-, AP-1-, or CREB-mediated transcription. Bioorg Med Chem Lett. 2008 Sep 15; 2008 Aug 6. PMID: 18722769

Da Silva CA, Hartl D, Liu W, Lee CG, Elias JA: TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation. J Immunol. 2008 Sep 15. PMID: 18768886

Harvey BP, Quan TE, Rudenga BJ, Roman RM, Craft J, Mamula MJ: Editing antigen presentation: antigen transfer between human B lymphocytes and macrophages mediated by class A scavenger receptors. J Immunol. 2008 Sep 15. PMID: 18768860

Rao Y, Lu M, Ge F, Marsh DJ, Qian S, Wang AH, Picciotto MR, Gao XB: Regulation of synaptic efficacy in hypocretin/orexin-containing neurons by melanin concentrating hormone in the lateral hypothalamus. J Neurosci. 2008 Sep 10. PMID: 18784290

Mamillapalli R, VanHouten J, Zawalich W, Wysolmerski J: Switching of G-protein usage by the calcium-sensing receptor reverses its effect on parathyroid hormone-related protein secretion in normal versus malignant breast cells. J Biol Chem. 2008 Sep 5; 2008 Jul 11. PMID: 18621740

Pan W, Choi SC, Wang H, Qin Y, Volpicelli-Daley L, Swan L, Lucast L, Khoo C, Zhang X, Li L, Abrams CS, Sokol SY, Wu D: Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation. Science. 2008 Sep 5. PMID: 18772438

Krystal JH: Capitalizing on extrasynaptic glutamate neurotransmission to treat antipsychotic-resistant symptoms in schizophrenia. Biol Psychiatry. 2008 Sep 1. PMID: 18694665

Addy NA, Bahi A, Taylor JR, Picciotto MR: Administration of the calcineurin inhibitor cyclosporine modulates cocaine-induced locomotor activity in rats. Psychopharmacology (Berl). 2008 Sep; 2008 Jun 28. PMID: 18587562

Saijo Y, Zhu D, Li J, Rubio V, Zhou Z, Shen Y, Hoecker U, Wang H, Deng XW: Arabidopsis COP1/SPA1 complex and FHY1/FHY3 associate with distinct phosphorylated forms of phytochrome A in balancing light signaling. Mol Cell. 2008 Aug 22. PMID: 18722184

Liu X, Hashimoto-Torii K, Torii M, Haydar TF, Rakic P: The role of ATP signaling in the migration of intermediate neuronal progenitors to the neocortical subventricular zone. Proc Natl Acad Sci U S A. 2008 Aug 19; 2008 Aug 8. PMID: 18689674

Kidd M, Drozdov I, Joseph R, Pfragner R, Culler M, Modlin I: Differential cytotoxicity of novel somatostatin and dopamine chimeric compounds on bronchopulmonary and small intestinal neuroendocrine tumor cell lines. Cancer. 2008 Aug 15. PMID: 18618499

Segi-Nishida E, Warner-Schmidt JL, Duman RS: Electroconvulsive seizure and VEGF increase the proliferation of neural stem-like cells in rat hippocampus. Proc Natl Acad Sci U S A. 2008 Aug 12; 2008 Aug 5. PMID: 18682560

Hains AB, Arnsten AF: Molecular mechanisms of stress-induced prefrontal cortical impairment: implications for mental illness. Learn Mem. 2008 Aug; 2008 Aug 6. PMID: 18685145

Laouar Y, Town T, Jeng D, Tran E, Wan Y, Kuchroo VK, Flavell RA: TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis. Proc Natl Acad Sci U S A. 2008 Aug 5; 2008 Jul 31. PMID: 18669656

Lee EJ, Holmes JW, Costa KD: Remodeling of engineered tissue anisotropy in response to altered loading conditions. Ann Biomed Eng. 2008 Aug; 2008 May 10. PMID: 18470621

Shirali AC, Goldstein DR: Tracking the toll of kidney disease. J Am Soc Nephrol. 2008 Aug; 2008 Jun 25. PMID: 18579638

Fitzgerald TN, Shepherd BR, Asada H, Teso D, Muto A, Fancher T, Pimiento JM, Maloney SP, Dardik A: Laminar shear stress stimulates vascular smooth muscle cell apoptosis via the Akt pathway. J Cell Physiol. 2008 Aug. PMID: 18247368

Shen H, Tesar BM, Walker WE, Goldstein DR: Dual signaling of MyD88 and TRIF is critical for maximal TLR4-induced dendritic cell maturation. J Immunol. 2008 Aug 1. PMID: 18641322

Torregrossa MM, Kalivas PW: Microdialysis and the neurochemistry of addiction. Pharmacol Biochem Behav. 2008 Aug; 2007 Sep 12. PMID: 17928041

Sudarsan N, Lee ER, Weinberg Z, Moy RH, Kim JN, Link KH, Breaker RR: Riboswitches in eubacteria sense the second messenger cyclic di-GMP. Science. 2008 Jul 18. PMID: 18635805

Sheridan DL, Kong Y, Parker SA, Dalby KN, Turk BE: Substrate discrimination among mitogen-activated protein kinases through distinct docking sequence motifs. J Biol Chem. 2008 Jul 11; 2008 May 15. PMID: 18482985

Dominguez MH, Rakic P: Neuroanatomy of the FGF system. J Comp Neurol. 2008 Jul 10. PMID: 18459136

Bordonaro M, Sartorelli AC: [Fiber, cancer stem cells, and the Wnt signaling continuum: possibilities for colorectal cancer prevention and therapeutics]. Ai Zheng. 2008 Jul. PMID: 18606074

Xu HP, Tian N: Glycine receptor-mediated synaptic transmission regulates the maturation of ganglion cell synaptic connectivity. J Comp Neurol. 2008 Jul 1. PMID: 18425804

Tomayko MM, Anderson SM, Brayton CE, Sadanand S, Steinel NC, Behrens TW, Shlomchik MJ: Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities. J Immunol. 2008 Jul 1. PMID: 18566367

Fogal B, Hewett SJ: Interleukin-1beta: a bridge between inflammation and excitotoxicity? J Neurochem. 2008 Jul; 2008 Jul 1. PMID: 18315560

Hawes JJ, Brunzell DH, Narasimhaiah R, Langel U, Wynick D, Picciotto MR: Galanin protects against behavioral and neurochemical correlates of opiate reward. Neuropsychopharmacology. 2008 Jul; 2007 Oct 24. PMID: 17957220

Snellman J, Kaur T, Shen Y, Nawy S: Regulation of ON bipolar cell activity. Prog Retin Eye Res. 2008 Jul; 2008 Apr 6. PMID: 18524666

Kim H, Chen J: New players in the BRCA1-mediated DNA damage responsive pathway. Mol Cells. 2008 Jun 30; 2008 Apr 24. PMID: 18443409

Torregrossa MM, Tang XC, Kalivas PW: The glutamatergic projection from the prefrontal cortex to the nucleus accumbens core is required for cocaine-induced decreases in ventral pallidal GABA. Neurosci Lett. 2008 Jun 20; 2008 Apr 10. PMID: 18455875

Shadel GS: Expression and maintenance of mitochondrial DNA: new insights into human disease pathology. Am J Pathol. 2008 Jun; 2008 May 5. PMID: 18458094

Shah AU, Grant WM, Latif SU, Mannan ZM, Park AJ, Husain SZ: Cyclic AMP accelerates calcium waves in pancreatic acinar cells. Am J Physiol Gastrointest Liver Physiol. 2008 Jun; 2008 Apr 3. PMID: 18388188

Shin S, Roy CR: Host cell processes that influence the intracellular survival of Legionella pneumophila. Cell Microbiol. 2008 Jun; 2008 Mar 17. PMID: 18363881

Picciotto MR: Galanin and addiction. Cell Mol Life Sci. 2008 Jun. PMID: 18500649

Biederer T, Stagi M: Signaling by synaptogenic molecules. Curr Opin Neurobiol. 2008 Jun. PMID: 18725297

Mara A, Schroeder J, Holley SA: Two deltaC splice-variants have distinct signaling abilities during somitogenesis and midline patterning. Dev Biol. 2008 Jun 1; 2008 Mar 20. PMID: 18430417

Kishimoto N, Cao Y, Park A, Sun Z: Cystic kidney gene seahorse regulates cilia-mediated processes and Wnt pathways. Dev Cell. 2008 Jun. PMID: 18539122

Stern DF: ERBB3/HER3 and ERBB2/HER2 duet in mammary development and breast cancer. J Mammary Gland Biol Neoplasia. 2008 Jun; 2008 May 3. PMID: 18454306

Town T, Laouar Y, Pittenger C, Mori T, Szekely CA, Tan J, Duman RS, Flavell RA: Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. Nat Med. 2008 Jun; 2008 Jun 1. PMID: 18516051

Gettinger S: Targeted therapy in advanced non-small-cell lung cancer. Semin Respir Crit Care Med. 2008 Jun. PMID: 18506667

Eminaga S, Bennett AM: Noonan syndrome-associated SHP-2/Ptpn11 mutants enhance SIRPalpha and PZR tyrosyl phosphorylation and promote adhesion-mediated ERK activation. J Biol Chem. 2008 May 30; 2008 Mar 31. PMID: 18378677

Heidrich FM, Zhang K, Estrada M, Huang Y, Giordano FJ, Ehrlich BE: Chromogranin B regulates calcium signaling, nuclear factor kappaB activity, and brain natriuretic peptide production in cardiomyocytes. Circ Res. 2008 May 23; 2008 Apr 17. PMID: 18420944

Harrisingh MC, Nitabach MN: Circadian rhythms. Integrating circadian timekeeping with cellular physiology. Science. 2008 May 16. PMID: 18487177

Müller Smith K, Fagel DM, Stevens HE, Rabenstein RL, Maragnoli ME, Ohkubo Y, Picciotto MR, Schwartz ML, Vaccarino FM: Deficiency in inhibitory cortical interneurons associates with hyperactivity in fibroblast growth factor receptor 1 mutant mice. Biol Psychiatry. 2008 May 15; 2007 Nov 7. PMID: 17988653

Luo D, He Y, Zhang H, Yu L, Chen H, Xu Z, Tang S, Urano F, Min W: AIP1 is critical in transducing IRE1-mediated endoplasmic reticulum stress response. J Biol Chem. 2008 May 2; 2008 Feb 15. PMID: 18281285

Gao Q, Horvath TL: Cross-talk between estrogen and leptin signaling in the hypothalamus. Am J Physiol Endocrinol Metab. 2008 May; 2008 Mar 11. PMID: 18334610

Rakoff-Nahoum S, Medzhitov R: Role of toll-like receptors in tissue repair and tumorigenesis. Biochemistry (Mosc). 2008 May. PMID: 18605980

Bordonaro M, Lazarova DL, Sartorelli AC: Butyrate and Wnt signaling: a possible solution to the puzzle of dietary fiber and colon cancer risk? Cell Cycle. 2008 May 1; 2008 Feb 26. PMID: 18418037

Diano S, Horvath TL: Type 3 deiodinase in hypoxia: to cool or to kill? Cell Metab. 2008 May. PMID: 18460327

Donnelly DF: Spontaneous action potential generation due to persistent sodium channel currents in simulated carotid body afferent fibers. J Appl Physiol (1985). 2008 May; 2008 Feb 28. PMID: 18309093

Vitiello D, Pinard R, Taylor HS: Gene expression profiling reveals putative HOXA10 downstream targets in the periimplantation mouse uterus. Reprod Sci. 2008 May. PMID: 18579861

Stocco C: Aromatase expression in the ovary: hormonal and molecular regulation. Steroids. 2008 May; 2008 Feb 1. PMID: 18321551

Cafferty WB, McGee AW, Strittmatter SM: Axonal growth therapeutics: regeneration or sprouting or plasticity? Trends Neurosci. 2008 May; 2008 Apr 7. PMID: 18395807

Buhimschi IA, Zhao G, Rosenberg VA, Abdel-Razeq S, Thung S, Buhimschi CS: Multidimensional proteomics analysis of amniotic fluid to provide insight into the mechanisms of idiopathic preterm birth. PLoS One. 2008 Apr 23; 2008 Apr 23. PMID: 18431506

Nath AK, Brown RM, Michaud M, Sierra-Honigmann MR, Snyder M, Madri JA: Leptin affects endocardial cushion formation by modulating EMT and migration via Akt signaling cascades. J Cell Biol. 2008 Apr 21; 2008 Apr 14. PMID: 18411306

Zhang Y, McKay SE, Bewley B, Kaczmarek LK: Repetitive firing triggers clustering of Kv2.1 potassium channels in Aplysia neurons. J Biol Chem. 2008 Apr 18; 2008 Feb 13. PMID: 18276591

Min W, Lin Y, Tang S, Yu L, Zhang H, Wan T, Luhn T, Fu H, Chen H: AIP1 recruits phosphatase PP2A to ASK1 in tumor necrosis factor-induced ASK1-JNK activation. Circ Res. 2008 Apr 11; 2008 Feb 21. PMID: 18292600

Djurisic M, Popovic M, Carnevale N, Zecevic D: Functional structure of the mitral cell dendritic tuft in the rat olfactory bulb. J Neurosci. 2008 Apr 9. PMID: 18400905

Lin B, Reinke V: The candidate MAP kinase phosphorylation substrate DPL-1 (DP) promotes expression of the MAP kinase phosphatase LIP-1 in C. elegans germ cells. Dev Biol. 2008 Apr 1; 2008 Jan 8. PMID: 18304523

Migliore M, Shepherd GM: Dendritic action potentials connect distributed dendrodendritic microcircuits. J Comput Neurosci. 2008 Apr; 2007 Aug 3. PMID: 17674173

Kagan JC, Su T, Horng T, Chow A, Akira S, Medzhitov R: TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-beta. Nat Immunol. 2008 Apr; 2008 Feb 24. PMID: 18297073

Picciotto MR, Addy NA, Mineur YS, Brunzell DH: It is not "either/or": activation and desensitization of nicotinic acetylcholine receptors both contribute to behaviors related to nicotine addiction and mood. Prog Neurobiol. 2008 Apr; 2007 Dec 27. PMID: 18242816

Koga K, Mor G: Expression and function of toll-like receptors at the maternal-fetal interface. Reprod Sci. 2008 Apr. PMID: 18421019

Vieyra-Reyes P, Picciotto MR, Mineur YS: Voluntary oral nicotine intake in mice down-regulates GluR2 but does not modulate depression-like behaviors. Neurosci Lett. 2008 Mar 21; 2008 Jan 16. PMID: 18261852

Guehl D, Benazzouz A, Aouizerate B, Cuny E, Rotgé JY, Rougier A, Tignol J, Bioulac B, Burbaud P: Neuronal correlates of obsessions in the caudate nucleus. Biol Psychiatry. 2008 Mar 15; 2007 Oct 22. PMID: 17945196

Jia-Lin Ma N, Stern DF: Regulation of the Rad53 protein kinase in signal amplification by oligomer assembly and disassembly. Cell Cycle. 2008 Mar 15; 2008 Jan 8. PMID: 18239457

Bai Y, Ahmad U, Wang Y, Li JH, Choy JC, Kim RW, Kirkiles-Smith N, Maher SE, Karras JG, Bennett CF, Bothwell AL, Pober JS, Tellides G: Interferon-gamma induces X-linked inhibitor of apoptosis-associated factor-1 and Noxa expression and potentiates human vascular smooth muscle cell apoptosis by STAT3 activation. J Biol Chem. 2008 Mar 14; 2008 Jan 11. PMID: 18192275

Idone V, Tam C, Goss JW, Toomre D, Pypaert M, Andrews NW: Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis. J Cell Biol. 2008 Mar 10; 2008 Mar 3. PMID: 18316410

Shahrokni A, Matuszczak J, Rajebi MR, Saif MW: Erlotinib-induced episcleritis in a patient with pancreatic cancer. JOP. 2008 Mar 8; 2008 Mar 8. PMID: 18326933

Bouaouina M, Lad Y, Calderwood DA: The N-terminal domains of talin cooperate with the phosphotyrosine binding-like domain to activate beta1 and beta3 integrins. J Biol Chem. 2008 Mar 7; 2007 Dec 28. PMID: 18165225

Emonet T, Cluzel P: Relationship between cellular response and behavioral variability in bacterial chemotaxis. Proc Natl Acad Sci U S A. 2008 Mar 4; 2008 Feb 25. PMID: 18299569

Yamasaki M, Kang HR, Homer RJ, Chapoval SP, Cho SJ, Lee BJ, Elias JA, Lee CG: P21 regulates TGF-beta1-induced pulmonary responses via a TNF-alpha-signaling pathway. Am J Respir Cell Mol Biol. 2008 Mar; 2007 Oct 11. PMID: 17932374

Chakraborty AK, Liang K, DiGiovanna MP: Co-targeting insulin-like growth factor I receptor and HER2: dramatic effects of HER2 inhibitors on nonoverexpressing breast cancer. Cancer Res. 2008 Mar 1. PMID: 18316619

Gibson CJ, Ehrlich BE: Inositol 1,4,5-trisphosphate receptor movement is restricted by addition of elevated levels of O-linked sugar. Cell Calcium. 2008 Mar; 2007 Jul 3. PMID: 17610951

Leranth C, Szigeti-Buck K, Maclusky NJ, Hajszan T: Bisphenol A prevents the synaptogenic response to testosterone in the brain of adult male rats. Endocrinology. 2008 Mar; 2007 Nov 29. PMID: 18048497

Gorelick F, Pandol S, Thrower E: Protein kinase C in the pancreatic acinar cell. J Gastroenterol Hepatol. 2008 Mar. PMID: 18336661

Maciejewski PK, Rothman DL: Proposed cycles for functional glutamate trafficking in synaptic neurotransmission. Neurochem Int. 2008 Mar-Apr; 2007 Oct 2. PMID: 18006192

Clark PR, Pober JS, Kluger MS: Knockdown of TNFR1 by the sense strand of an ICAM-1 siRNA: dissection of an off-target effect. Nucleic Acids Res. 2008 Mar; 2007 Dec 20. PMID: 18096615

Schmidt EF, Shim SO, Strittmatter SM: Release of MICAL autoinhibition by semaphorin-plexin signaling promotes interaction with collapsin response mediator protein. J Neurosci. 2008 Feb 27. PMID: 18305261

Brennan AR, Dolinsky B, Vu MA, Stanley M, Yeckel MF, Arnsten AF: Blockade of IP3-mediated SK channel signaling in the rat medial prefrontal cortex improves spatial working memory. Learn Mem. 2008 Mar; 2008 Feb 19. PMID: 18285467

Gomes DA, Rodrigues MA, Leite MF, Gomez MV, Varnai P, Balla T, Bennett AM, Nathanson MH: c-Met must translocate to the nucleus to initiate calcium signals. J Biol Chem. 2008 Feb 15; 2007 Dec 11. PMID: 18073207

Young LH: AMP-activated protein kinase conducts the ischemic stress response orchestra. Circulation. 2008 Feb 12. PMID: 18268160

Li H, Chen Y, Jones AF, Sanger RH, Collis LP, Flannery R, McNay EC, Yu T, Schwarzenbacher R, Bossy B, Bossy-Wetzel E, Bennett MV, Pypaert M, Hickman JA, Smith PJ, Hardwick JM, Jonas EA: Bcl-xL induces Drp1-dependent synapse formation in cultured hippocampal neurons. Proc Natl Acad Sci U S A. 2008 Feb 12; 2008 Feb 4. PMID: 18250306

Hayden MS, Ghosh S: Shared principles in NF-kappaB signaling. Cell. 2008 Feb 8. PMID: 18267068

Pang H, Zhao H: Building pathway clusters from Random Forests classification using class votes. BMC Bioinformatics. 2008 Feb 6; 2008 Feb 6. PMID: 18254968

Unni AM, Bondar T, Medzhitov R: Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance. Proc Natl Acad Sci U S A. 2008 Feb 5; 2008 Jan 25. PMID: 18223157

Hagenston AM, Fitzpatrick JS, Yeckel MF: MGluR-mediated calcium waves that invade the soma regulate firing in layer V medial prefrontal cortical pyramidal neurons. Cereb Cortex. 2008 Feb; 2007 Jun 14. PMID: 17573372

Shirali AC, Goldstein DR: Activation of the innate immune system by the endogenous ligand hyaluronan. Curr Opin Organ Transplant. 2008 Feb. PMID: 18660702

Elsworth JD, Jentsch JD, Morrow BA, Redmond DE Jr, Roth RH: Clozapine normalizes prefrontal cortex dopamine transmission in monkeys subchronically exposed to phencyclidine. Neuropsychopharmacology. 2008 Feb; 2007 May 16. PMID: 17507917

Yaba A, Bianchi V, Borini A, Johnson J: A putative mitotic checkpoint dependent on mTOR function controls cell proliferation and survival in ovarian granulosa cells. Reprod Sci. 2008 Feb. PMID: 18276949

Yuzawa S, Schlessinger J: [Structural biology of receptor tyrosine kinase kit]. Seikagaku. 2008 Feb. PMID: 18341028

Sarkisian MR, Bartley CM, Rakic P: Trouble making the first move: interpreting arrested neuronal migration in the cerebral cortex. Trends Neurosci. 2008 Feb; 2008 Jan 16. PMID: 18201775

Miller EJ, Li J, Leng L, McDonald C, Atsumi T, Bucala R, Young LH: Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature. 2008 Jan 31. PMID: 18235500

Schafe GE, Swank MW, Rodrigues SM, Debiec J, Doyère V: Phosphorylation of ERK/MAP kinase is required for long-term potentiation in anatomically restricted regions of the lateral amygdala in vivo. Learn Mem. 2008 Feb; 2008 Jan 28. PMID: 18230673

Feng S, Martinez C, Gusmaroli G, Wang Y, Zhou J, Wang F, Chen L, Yu L, Iglesias-Pedraz JM, Kircher S, Schäfer E, Fu X, Fan LM, Deng XW: Coordinated regulation of Arabidopsis thaliana development by light and gibberellins. Nature. 2008 Jan 24. PMID: 18216856

Zhang W, Cho Y, Lolis E, Howe JR: Structural and single-channel results indicate that the rates of ligand binding domain closing and opening directly impact AMPA receptor gating. J Neurosci. 2008 Jan 23. PMID: 18216201

Yagi T, Giallourakis C, Mohanty S, Scheidig C, Shen J, Zheng H, Xavier RJ, Shaw AC: Defective signal transduction in B lymphocytes lacking presenilin proteins. Proc Natl Acad Sci U S A. 2008 Jan 22; 2008 Jan 14. PMID: 18195359

Gao W, Chen AP, Leung CH, Gullen EA, Fürstner A, Shi Q, Wei L, Lee KH, Cheng YC: Structural analogs of tylophora alkaloids may not be functional analogs. Bioorg Med Chem Lett. 2008 Jan 15; 2007 Nov 21. PMID: 18077159

Koo JW, Duman RS: IL-1beta is an essential mediator of the antineurogenic and anhedonic effects of stress. Proc Natl Acad Sci U S A. 2008 Jan 15; 2008 Jan 4. PMID: 18178625

Schleicher M, Shepherd BR, Suarez Y, Fernandez-Hernando C, Yu J, Pan Y, Acevedo LM, Shadel GS, Sessa WC: Prohibitin-1 maintains the angiogenic capacity of endothelial cells by regulating mitochondrial function and senescence. J Cell Biol. 2008 Jan 14. PMID: 18195103

Chen R, Alvero AB, Silasi DA, Steffensen KD, Mor G: Cancers take their Toll--the function and regulation of Toll-like receptors in cancer cells. Oncogene. 2008 Jan 7. PMID: 18176604

Shah RD, Crair MC: Retinocollicular synapse maturation and plasticity are regulated by correlated retinal waves. J Neurosci. 2008 Jan 2. PMID: 18171946

Cirone P, Lin S, Griesbach HL, Zhang Y, Slusarski DC, Crews CM: A role for planar cell polarity signaling in angiogenesis. Angiogenesis. 2008; 2008 Sep 17. PMID: 18798004

Miao RQ, Fontana J, Fulton D, Lin MI, Harrison KD, Sessa WC: Dominant-negative Hsp90 reduces VEGF-stimulated nitric oxide release and migration in endothelial cells. Arterioscler Thromb Vasc Biol. 2008 Jan; 2007 Nov 1. PMID: 17975117

Huen MS, Chen J: The DNA damage response pathways: at the crossroad of protein modifications. Cell Res. 2008 Jan. PMID: 18087291

Bifulco C, McDaniel K, Leng L, Bucala R: Tumor growth-promoting properties of macrophage migration inhibitory factor. Curr Pharm Des. 2008. PMID: 19128232

Pan JW, Williamson A, Cavus I, Hetherington HP, Zaveri H, Petroff OA, Spencer DD: Neurometabolism in human epilepsy. Epilepsia. 2008. PMID: 18304254

Picciotto MR, Zoli M: Neuroprotection via nAChRs: the role of nAChRs in neurodegenerative disorders such as Alzheimer's and Parkinson's disease. Front Biosci. 2008 Jan 1; 2008 Jan 1. PMID: 17981563

Tanis JE, Moresco JJ, Lindquist RA, Koelle MR: Regulation of serotonin biosynthesis by the G proteins Galphao and Galphaq controls serotonin signaling in Caenorhabditis elegans. Genetics. 2008 Jan. PMID: 18202365

Matza D, Badou A, Kobayashi KS, Goldsmith-Pestana K, Masuda Y, Komuro A, McMahon-Pratt D, Marchesi VT, Flavell RA: A scaffold protein, AHNAK1, is required for calcium signaling during T cell activation. Immunity. 2008 Jan. PMID: 18191595

Abrahams VM: Pattern recognition at the maternal-fetal interface. Immunol Invest. 2008. PMID: 18716932

Diano S, Horvath TL: Anticonvulsant effects of leptin in epilepsy. J Clin Invest. 2008 Jan. PMID: 18097479

Wang Z, Liu B, Wang P, Dong X, Fernandez-Hernando C, Li Z, Hla T, Li Z, Claffey K, Smith JD, Wu D: Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice. J Clin Invest. 2008 Jan. PMID: 18079968

Sanacora G: New understanding of mechanisms of action of bipolar medications. J Clin Psychiatry. 2008. PMID: 19265637

Huang Y, Giordano FJ: Chapter 13. Oxygen as a direct and indirect biological determinant in the vasculature. Methods Enzymol. 2008. PMID: 19007670

Derakhshan B, Harrison KD, Miao QR, Sessa WC: Approaches for studying angiogenesis-related signal transduction. Methods Enzymol. 2008. PMID: 18772008

Lin ZP, Zhu YL, Johnson DR, Rice KP, Nottoli T, Hains BC, McGrath J, Waxman SG, Sartorelli AC: Disruption of cAMP and prostaglandin E2 transport by multidrug resistance protein 4 deficiency alters cAMP-mediated signaling and nociceptive response. Mol Pharmacol. 2008 Jan; 2007 Oct 24. PMID: 17959714

Kim PM, Sboner A, Xia Y, Gerstein M: The role of disorder in interaction networks: a structural analysis. Mol Syst Biol. 2008; 2008 Mar 25. PMID: 18364713

Pittenger C, Duman RS: Stress, depression, and neuroplasticity: a convergence of mechanisms. Neuropsychopharmacology. 2008 Jan; 2007 Sep 12. PMID: 17851537

Bordonaro M, Lazarova DL, Sartorelli AC: Hyperinduction of Wnt activity: a new paradigm for the treatment of colorectal cancer? Oncol Res. 2008. PMID: 18488710

Wang Z, Cao G, Wang X, Miao J, Liu X, Chen Z, Qu LJ, Gu H: Identification and characterization of COI1-dependent transcription factor genes involved in JA-mediated response to wounding in Arabidopsis plants. Plant Cell Rep. 2008 Jan; 2007 Sep 5. PMID: 17786451

Kodaman PH, Duleba AJ: Statins in the treatment of polycystic ovary syndrome. Semin Reprod Med. 2008 Jan. PMID: 18181091

Maandag NJ, Coman D, Sanganahalli BG, Herman P, Smith AJ, Blumenfeld H, Shulman RG, Hyder F: Energetics of neuronal signaling and fMRI activity. Proc Natl Acad Sci U S A. 2007 Dec 18; 2007 Dec 13. PMID: 18079290

Breunig JJ, Silbereis J, Vaccarino FM, Sestan N, Rakic P: Notch regulates cell fate and dendrite morphology of newborn neurons in the postnatal dentate gyrus. Proc Natl Acad Sci U S A. 2007 Dec 18; 2007 Dec 11. PMID: 18077357

Rengifo J, Gibson CJ, Winkler E, Collin T, Ehrlich BE: Regulation of the inositol 1,4,5-trisphosphate receptor type I by O-GlcNAc glycosylation. J Neurosci. 2007 Dec 12. PMID: 18077693

Wu Y, Wang W, Díez-Sampedro A, Richerson GB: Nonvesicular inhibitory neurotransmission via reversal of the GABA transporter GAT-1. Neuron. 2007 Dec 6. PMID: 18054861

Takizawa BT, Uchio EM, Cohen JJ, Wheeler MA, Weiss RM: Downregulation of survivin is associated with reductions in TNF receptors' mRNA and protein and alterations in nuclear factor kappa B signaling in urothelial cancer cells. Cancer Invest. 2007 Dec. PMID: 18058462

McNay EC: Insulin and ghrelin: peripheral hormones modulating memory and hippocampal function. Curr Opin Pharmacol. 2007 Dec; 2007 Nov 26. PMID: 18023257

Krueger DD, Nairn AC: Expression of PKC substrate proteins, GAP-43 and neurogranin, is downregulated by cAMP signaling and alterations in synaptic activity. Eur J Neurosci. 2007 Dec; 2007 Nov 14. PMID: 18005072

Preisig PA: The acid-activated signaling pathway: starting with Pyk2 and ending with increased NHE3 activity. Kidney Int. 2007 Dec; 2007 Sep 19. PMID: 17882150

D'Souza AD, Parikh N, Kaech SM, Shadel GS: Convergence of multiple signaling pathways is required to coordinately up-regulate mtDNA and mitochondrial biogenesis during T cell activation. Mitochondrion. 2007 Dec; 2007 Aug 16. PMID: 17890163

Horng T, Bezbradica JS, Medzhitov R: NKG2D signaling is coupled to the interleukin 15 receptor signaling pathway. Nat Immunol. 2007 Dec; 2007 Oct 21. PMID: 17952078

Mara A, Holley SA: Oscillators and the emergence of tissue organization during zebrafish somitogenesis. Trends Cell Biol. 2007 Dec; 2007 Nov 7. PMID: 17988868

Huen MS, Grant R, Manke I, Minn K, Yu X, Yaffe MB, Chen J: RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell. 2007 Nov 30; 2007 Nov 20. PMID: 18001825

Kang HJ, Adams DH, Simen A, Simen BB, Rajkowska G, Stockmeier CA, Overholser JC, Meltzer HY, Jurjus GJ, Konick LC, Newton SS, Duman RS: Gene expression profiling in postmortem prefrontal cortex of major depressive disorder. J Neurosci. 2007 Nov 28. PMID: 18045927

Chapoval SP, Al-Garawi A, Lora JM, Strickland I, Ma B, Lee PJ, Homer RJ, Ghosh S, Coyle AJ, Elias JA: Inhibition of NF-kappaB activation reduces the tissue effects of transgenic IL-13. J Immunol. 2007 Nov 15. PMID: 17982094

Kim HR, Hwang KA, Kang I: Dual roles of IL-15 in maintaining IL-7RalphalowCCR7- memory CD8+ T cells in humans via recovering the phosphatidylinositol 3-kinase/AKT pathway. J Immunol. 2007 Nov 15. PMID: 17982063

Fogel AI, Akins MR, Krupp AJ, Stagi M, Stein V, Biederer T: SynCAMs organize synapses through heterophilic adhesion. J Neurosci. 2007 Nov 14. PMID: 18003830

Harrisingh MC, Wu Y, Lnenicka GA, Nitabach MN: Intracellular Ca2+ regulates free-running circadian clock oscillation in vivo. J Neurosci. 2007 Nov 14. PMID: 18003827

Sigworth FJ: The last few frames of the voltage-gating movie. Biophys J. 2007 Nov 1; 2007 Aug 17. PMID: 17704178

Fiorotto R, Spirlì C, Fabris L, Cadamuro M, Okolicsanyi L, Strazzabosco M: Ursodeoxycholic acid stimulates cholangiocyte fluid secretion in mice via CFTR-dependent ATP secretion. Gastroenterology. 2007 Nov; 2007 Sep 2. PMID: 17983806

Watanabe A, Hashmi A, Gomes DA, Town T, Badou A, Flavell RA, Mehal WZ: Apoptotic hepatocyte DNA inhibits hepatic stellate cell chemotaxis via toll-like receptor 9. Hepatology. 2007 Nov. PMID: 17705260

McCarthy TL, Pham TH, Knoll BI, Centrella M: Prostaglandin E2 increases transforming growth factor-beta type III receptor expression through CCAAT enhancer-binding protein delta in osteoblasts. Mol Endocrinol. 2007 Nov; 2007 Jul 17. PMID: 17636036

Venkitaramani DV, Chin J, Netzer WJ, Gouras GK, Lesne S, Malinow R, Lombroso PJ: Beta-amyloid modulation of synaptic transmission and plasticity. J Neurosci. 2007 Oct 31. PMID: 17978019

Duric V, McCarson KE: Neurokinin-1 (NK-1) receptor and brain-derived neurotrophic factor (BDNF) gene expression is differentially modulated in the rat spinal dorsal horn and hippocampus during inflammatory pain. Mol Pain. 2007 Oct 31; 2007 Oct 31. PMID: 17974009

Huang H, van den Pol AN: Rapid direct excitation and long-lasting enhancement of NMDA response by group I metabotropic glutamate receptor activation of hypothalamic melanin-concentrating hormone neurons. J Neurosci. 2007 Oct 24. PMID: 17959799

Kim ST, Fields PE, Flavell RA: Demethylation of a specific hypersensitive site in the Th2 locus control region. Proc Natl Acad Sci U S A. 2007 Oct 23; 2007 Oct 12. PMID: 17940027

Zhang D, Liu ZX, Choi CS, Tian L, Kibbey R, Dong J, Cline GW, Wood PA, Shulman GI: Mitochondrial dysfunction due to long-chain Acyl-CoA dehydrogenase deficiency causes hepatic steatosis and hepatic insulin resistance. Proc Natl Acad Sci U S A. 2007 Oct 23; 2007 Oct 16. PMID: 17940018

Li L, Hisamoto K, Kim KH, Haynes MP, Bauer PM, Sanjay A, Collinge M, Baron R, Sessa WC, Bender JR: Variant estrogen receptor-c-Src molecular interdependence and c-Src structural requirements for endothelial NO synthase activation. Proc Natl Acad Sci U S A. 2007 Oct 16; 2007 Oct 5. PMID: 17921256

Murata T, Lin MI, Huang Y, Yu J, Bauer PM, Giordano FJ, Sessa WC: Reexpression of caveolin-1 in endothelium rescues the vascular, cardiac, and pulmonary defects in global caveolin-1 knockout mice. J Exp Med. 2007 Oct 1; 2007 Sep 24. PMID: 17893196

Pedra JH, Sutterwala FS, Sukumaran B, Ogura Y, Qian F, Montgomery RR, Flavell RA, Fikrig E: ASC/PYCARD and caspase-1 regulate the IL-18/IFN-gamma axis during Anaplasma phagocytophilum infection. J Immunol. 2007 Oct 1. PMID: 17878377

Steiner RC, Heath CJ, Picciotto MR: Nicotine-induced phosphorylation of ERK in mouse primary cortical neurons: evidence for involvement of glutamatergic signaling and CaMKII. J Neurochem. 2007 Oct; 2007 Jul 31. PMID: 17666046

Hu Y, Zhang Y, Venkitaramani DV, Lombroso PJ: Translation of striatal-enriched protein tyrosine phosphatase (STEP) after beta1-adrenergic receptor stimulation. J Neurochem. 2007 Oct; 2007 Jul 10. PMID: 17623046

Shams I, Rohmann E, Eswarakumar VP, Lew ED, Yuzawa S, Wollnik B, Schlessinger J, Lax I: Lacrimo-auriculo-dento-digital syndrome is caused by reduced activity of the fibroblast growth factor 10 (FGF10)-FGF receptor 2 signaling pathway. Mol Cell Biol. 2007 Oct; 2007 Aug 6. PMID: 17682060

Schwartz DC, Felberbaum R, Hochstrasser M: The Ulp2 SUMO protease is required for cell division following termination of the DNA damage checkpoint. Mol Cell Biol. 2007 Oct; 2007 Jul 30. PMID: 17664284

Pober JS, Sessa WC: Evolving functions of endothelial cells in inflammation. Nat Rev Immunol. 2007 Oct. PMID: 17893694

Schmandke A, Schmandke A, Strittmatter SM: ROCK and Rho: biochemistry and neuronal functions of Rho-associated protein kinases. Neuroscientist. 2007 Oct. PMID: 17901255

Kim BJ, Fulton AB: The genetics and ocular findings of Alagille syndrome. Semin Ophthalmol. 2007 Oct-Dec. PMID: 18097983

Brodsky I, Medzhitov R: Two modes of ligand recognition by TLRs. Cell. 2007 Sep 21. PMID: 17889640

Cho CH, St-Gelais F, Zhang W, Tomita S, Howe JR: Two families of TARP isoforms that have distinct effects on the kinetic properties of AMPA receptors and synaptic currents. Neuron. 2007 Sep 20. PMID: 17880893

Gil-Henn H, Destaing O, Sims NA, Aoki K, Alles N, Neff L, Sanjay A, Bruzzaniti A, De Camilli P, Baron R, Schlessinger J: Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2(-/-) mice. J Cell Biol. 2007 Sep 10. PMID: 17846174

Duman RS: A silver bullet for the treatment of depression? Neuron. 2007 Sep 6. PMID: 17785173

Lee JJ, Chu E: An update on treatment advances for the first-line therapy of metastatic colorectal cancer. Cancer J. 2007 Sep-Oct. PMID: 17921724

Lin Z, Yin K, Zhu D, Chen Z, Gu H, Qu LJ: AtCDC5 regulates the G2 to M transition of the cell cycle and is critical for the function of Arabidopsis shoot apical meristem. Cell Res. 2007 Sep. PMID: 17768399

Arnsten AF: Catecholamine and second messenger influences on prefrontal cortical networks of "representational knowledge": a rational bridge between genetics and the symptoms of mental illness. Cereb Cortex. 2007 Sep; 2007 Apr 13. PMID: 17434919

Xue L, Igaki T, Kuranaga E, Kanda H, Miura M, Xu T: Tumor suppressor CYLD regulates JNK-induced cell death in Drosophila. Dev Cell. 2007 Sep. PMID: 17765686

Boyle SN, Koleske AJ: Dissecting kinase signaling pathways. Drug Discov Today. 2007 Sep; 2007 Aug 23. PMID: 17826684

Nishimura K, Blume P, Ohgi S, Sumpio BE: Effect of different frequencies of tensile strain on human dermal fibroblast proliferation and survival. Wound Repair Regen. 2007 Sep-Oct. PMID: 17971010

Burch-Smith TM, Dinesh-Kumar SP: The functions of plant TIR domains. Sci STKE. 2007 Aug 28; 2007 Aug 28. PMID: 17726177

Zhang L, Caplan MJ: Transport protein sorting in polarized epithelial cells. Sheng Li Xue Bao. 2007 Aug 25. PMID: 17700970

Kim Y, Sun H: Functional genomic approach to identify novel genes involved in the regulation of oxidative stress resistance and animal lifespan. Aging Cell. 2007 Aug; 2007 Jul 3. PMID: 17608836

Krikun G, Lockwood CJ, Abrahams VM, Mor G, Paidas M, Guller S: Expression of Toll-like receptors in the human decidua. Histol Histopathol. 2007 Aug. PMID: 17503341

Correa PR, Kruglov EA, Thompson M, Leite MF, Dranoff JA, Nathanson MH: Succinate is a paracrine signal for liver damage. J Hepatol. 2007 Aug; 2007 Apr 5. PMID: 17451837

Herold K, Moser B, Chen Y, Zeng S, Yan SF, Ramasamy R, Emond J, Clynes R, Schmidt AM: Receptor for advanced glycation end products (RAGE) in a dash to the rescue: inflammatory signals gone awry in the primal response to stress. J Leukoc Biol. 2007 Aug; 2007 May 18. PMID: 17513693

Platel JC, Lacar B, Bordey A: GABA and glutamate signaling: homeostatic control of adult forebrain neurogenesis. J Mol Histol. 2007 Aug; 2007 Jun 7. PMID: 17554632

Kim H, Huang J, Chen J: CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response. Nat Struct Mol Biol. 2007 Aug; 2007 Jul 22. PMID: 17643122

Rizzolo LJ, Chen X, Weitzman M, Sun R, Zhang H: Analysis of the RPE transcriptome reveals dynamic changes during the development of the outer blood-retinal barrier. Mol Vis. 2007 Jul 23; 2007 Jul 23. PMID: 17679949

Xu HP, Tian N: Retinal ganglion cell dendrites undergo a visual activity-dependent redistribution after eye opening. J Comp Neurol. 2007 Jul 10. PMID: 17492624

Rakoff-Nahoum S, Medzhitov R: Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88. Science. 2007 Jul 6. PMID: 17615359

Knezevic D, Zhang W, Rochette PJ, Brash DE: Bcl-2 is the target of a UV-inducible apoptosis switch and a node for UV signaling. Proc Natl Acad Sci U S A. 2007 Jul 3; 2007 Jun 22. PMID: 17586682

Zhou Y, Bouyer P, Boron WF: Role of the AT1A receptor in the CO2-induced stimulation of HCO3- reabsorption by renal proximal tubules. Am J Physiol Renal Physiol. 2007 Jul; 2007 Mar 13. PMID: 17356125

Nagata J, Guerra MT, Shugrue CA, Gomes DA, Nagata N, Nathanson MH: Lipid rafts establish calcium waves in hepatocytes. Gastroenterology. 2007 Jul; 2007 Apr 11. PMID: 17631147

Amsen D, Antov A, Jankovic D, Sher A, Radtke F, Souabni A, Busslinger M, McCright B, Gridley T, Flavell RA: Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity. 2007 Jul; 2007 Jul 19. PMID: 17658279

Ho WS, van den Pol AN: Bystander attenuation of neuronal and astrocyte intercellular communication by murine cytomegalovirus infection of glia. J Virol. 2007 Jul; 2007 Apr 25. PMID: 17459923

Ford JM, Krystal JH, Mathalon DH: Neural synchrony in schizophrenia: from networks to new treatments. Schizophr Bull. 2007 Jul; 2007 Jun 13. PMID: 17567628

Lu LJ, Sboner A, Huang YJ, Lu HX, Gianoulis TA, Yip KY, Kim PM, Montelione GT, Gerstein MB: Comparing classical pathways and modern networks: towards the development of an edge ontology. Trends Biochem Sci. 2007 Jul; 2007 Jun 20. PMID: 17583513

Boehmerle W, Zhang K, Sivula M, Heidrich FM, Lee Y, Jordt SE, Ehrlich BE: Chronic exposure to paclitaxel diminishes phosphoinositide signaling by calpain-mediated neuronal calcium sensor-1 degradation. Proc Natl Acad Sci U S A. 2007 Jun 26; 2007 Jun 20. PMID: 17581879

Kidd M, Modlin IM, Pfragner R, Eick GN, Champaneria MC, Chan AK, Camp RL, Mane SM: Small bowel carcinoid (enterochromaffin cell) neoplasia exhibits transforming growth factor-beta1-mediated regulatory abnormalities including up-regulation of C-Myc and MTA1. Cancer. 2007 Jun 15. PMID: 17469181

Rodrigues MA, Gomes DA, Leite MF, Grant W, Zhang L, Lam W, Cheng YC, Bennett AM, Nathanson MH: Nucleoplasmic calcium is required for cell proliferation. J Biol Chem. 2007 Jun 8; 2007 Apr 9. PMID: 17420246

Husain SZ, Grant WM, Gorelick FS, Nathanson MH, Shah AU: Caerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin. Am J Physiol Gastrointest Liver Physiol. 2007 Jun; 2007 Mar 1. PMID: 17332472

DeWan A, Bracken MB, Hoh J: Two genetic pathways for age-related macular degeneration. Curr Opin Genet Dev. 2007 Jun; 2007 Apr 27. PMID: 17467263

Baron R, Rawadi G: Targeting the Wnt/beta-catenin pathway to regulate bone formation in the adult skeleton. Endocrinology. 2007 Jun; 2007 Mar 29. PMID: 17395698

Gipson KE, Yeckel MF: Coincident glutamatergic and cholinergic inputs transiently depress glutamate release at rat schaffer collateral synapses. J Neurophysiol. 2007 Jun; 2007 Feb 15. PMID: 17303811

Muto A, Fitzgerald TN, Pimiento JM, Maloney SP, Teso D, Paszkowiak JJ, Westvik TS, Kudo FA, Nishibe T, Dardik A: Smooth muscle cell signal transduction: implications of vascular biology for vascular surgeons. J Vasc Surg. 2007 Jun. PMID: 17544020

Ziello JE, Jovin IS, Huang Y: Hypoxia-Inducible Factor (HIF)-1 regulatory pathway and its potential for therapeutic intervention in malignancy and ischemia. Yale J Biol Med. 2007 Jun. PMID: 18160990

Patrick Harty T, Waxman SG: Inactivation properties of sodium channel Nav1.8 maintain action potential amplitude in small DRG neurons in the context of depolarization. Mol Pain. 2007 May 31; 2007 May 31. PMID: 17540018

Igaki T, Suzuki Y, Tokushige N, Aonuma H, Takahashi R, Miura M: Evolution of mitochondrial cell death pathway: Proapoptotic role of HtrA2/Omi in Drosophila. Biochem Biophys Res Commun. 2007 May 18; 2007 Mar 26. PMID: 17397804

Zhang H, Zhang H, Lin Y, Li J, Pober JS, Min W: RIP1-mediated AIP1 phosphorylation at a 14-3-3-binding site is critical for tumor necrosis factor-induced ASK1-JNK/p38 activation. J Biol Chem. 2007 May 18; 2007 Mar 27. PMID: 17389591

Parker MD, Young MT, Daly CM, Meech RW, Boron WF, Tanner MJ: A conductive pathway generated from fragments of the human red cell anion exchanger AE1. J Physiol. 2007 May 15; 2007 Feb 22. PMID: 17317744

Soldatov NM, Weiss JN: Principles of calcium signaling. Salisbury Cove, Maine, June 28-30, 2007. Channels (Austin). 2007 May-Jun. PMID: 18702192

Bordonaro M, Lazarova DL, Sartorelli AC: The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors. Exp Cell Res. 2007 May 1; 2007 Feb 22. PMID: 17359971

Tesar BM, Goldstein DR: Toll-like receptors and their role in transplantation. Front Biosci. 2007 May 1; 2007 May 1. PMID: 17485369

Mara A, Schroeder J, Chalouni C, Holley SA: Priming, initiation and synchronization of the segmentation clock by deltaD and deltaC. Nat Cell Biol. 2007 May; 2007 Apr 8. PMID: 17417625

Ferguson SM, Brasnjo G, Hayashi M, Wölfel M, Collesi C, Giovedi S, Raimondi A, Gong LW, Ariel P, Paradise S, O'toole E, Flavell R, Cremona O, Miesenböck G, Ryan TA, De Camilli P: A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis. Science. 2007 Apr 27. PMID: 17463283

Yu H, Kim PM, Sprecher E, Trifonov V, Gerstein M: The importance of bottlenecks in protein networks: correlation with gene essentiality and expression dynamics. PLoS Comput Biol. 2007 Apr 20; 2007 Feb 14. PMID: 17447836

Uboha NV, Flajolet M, Nairn AC, Picciotto MR: A calcium- and calmodulin-dependent kinase Ialpha/microtubule affinity regulating kinase 2 signaling cascade mediates calcium-dependent neurite outgrowth. J Neurosci. 2007 Apr 18. PMID: 17442826

Jonason JH, Gavrilova N, Wu M, Zhang H, Sun H: Regulation of SCF(SKP2) ubiquitin E3 ligase assembly and p27(KIP1) proteolysis by the PTEN pathway and cyclin D1. Cell Cycle. 2007 Apr 15; 2007 Apr 5. PMID: 17438373

Liang G, Cline GW, Macica CM: IGF-1 stimulates de novo fatty acid biosynthesis by Schwann cells during myelination. Glia. 2007 Apr 15. PMID: 17299765

Zhou Y, Atkins JB, Rompani SB, Bancescu DL, Petersen PH, Tang H, Zou K, Stewart SB, Zhong W: The mammalian Golgi regulates numb signaling in asymmetric cell division by releasing ACBD3 during mitosis. Cell. 2007 Apr 6. PMID: 17418793

Kruglov EA, Correa PR, Arora G, Yu J, Nathanson MH, Dranoff JA: Molecular basis for calcium signaling in hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol. 2007 Apr; 2007 Jan 4. PMID: 17204544

Bonawitz ND, Chatenay-Lapointe M, Pan Y, Shadel GS: Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression. Cell Metab. 2007 Apr. PMID: 17403371

Tanis KQ, Newton SS, Duman RS: Targeting neurotrophic/growth factor expression and signaling for antidepressant drug development. CNS Neurol Disord Drug Targets. 2007 Apr. PMID: 17430152

Donnelly DF: Orthodromic spike generation from electrical stimuli in the rat carotid body: implications for the afferent spike generation process. J Physiol. 2007 Apr 1; 2007 Jan 18. PMID: 17234702

Waxman SG: Channel, neuronal and clinical function in sodium channelopathies: from genotype to phenotype. Nat Neurosci. 2007 Apr. PMID: 17387329

Lynch WJ, Kiraly DD, Caldarone BJ, Picciotto MR, Taylor JR: Effect of cocaine self-administration on striatal PKA-regulated signaling in male and female rats. Psychopharmacology (Berl). 2007 Apr; 2006 Dec 16. PMID: 17180335

Hernandez E, Leite MF, Guerra MT, Kruglov EA, Bruna-Romero O, Rodrigues MA, Gomes DA, Giordano FJ, Dranoff JA, Nathanson MH: The spatial distribution of inositol 1,4,5-trisphosphate receptor isoforms shapes Ca2+ waves. J Biol Chem. 2007 Mar 30; 2007 Feb 6. PMID: 17284437

Baker BJ, Lee H, Pieribone VA, Cohen LB, Isacoff EY, Knopfel T, Kosmidis EK: Three fluorescent protein voltage sensors exhibit low plasma membrane expression in mammalian cells. J Neurosci Methods. 2007 Mar 30; 2006 Nov 28. PMID: 17126911

Turk BE: Manipulation of host signalling pathways by anthrax toxins. Biochem J. 2007 Mar 15. PMID: 17313374

Warner-Schmidt JL, Duman RS: VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants. Proc Natl Acad Sci U S A. 2007 Mar 13; 2007 Mar 5. PMID: 17360578

Leuenroth SJ, Okuhara D, Shotwell JD, Markowitz GS, Yu Z, Somlo S, Crews CM: Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease. Proc Natl Acad Sci U S A. 2007 Mar 13; 2007 Mar 6. PMID: 17360534

Zito CI, Qin H, Blenis J, Bennett AM: SHP-2 regulates cell growth by controlling the mTOR/S6 kinase 1 pathway. J Biol Chem. 2007 Mar 9; 2007 Jan 17. PMID: 17229738

Taylor JR, Lynch WJ, Sanchez H, Olausson P, Nestler EJ, Bibb JA: Inhibition of Cdk5 in the nucleus accumbens enhances the locomotor-activating and incentive-motivational effects of cocaine. Proc Natl Acad Sci U S A. 2007 Mar 6; 2007 Feb 23. PMID: 17360491

Ring AM, Leng Q, Rinehart J, Wilson FH, Kahle KT, Hebert SC, Lifton RP: An SGK1 site in WNK4 regulates Na+ channel and K+ channel activity and has implications for aldosterone signaling and K+ homeostasis. Proc Natl Acad Sci U S A. 2007 Mar 6; 2007 Feb 22. PMID: 17360471

Mani A, Radhakrishnan J, Wang H, Mani A, Mani MA, Nelson-Williams C, Carew KS, Mane S, Najmabadi H, Wu D, Lifton RP: LRP6 mutation in a family with early coronary disease and metabolic risk factors. Science. 2007 Mar 2. PMID: 17332414

Uhrenholt TR, Domeier TL, Segal SS: Propagation of calcium waves along endothelium of hamster feed arteries. Am J Physiol Heart Circ Physiol. 2007 Mar; 2006 Nov 10. PMID: 17098832

Duman CH, Schlesinger L, Kodama M, Russell DS, Duman RS: A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biol Psychiatry. 2007 Mar 1; 2006 Aug 30. PMID: 16945347

Hens JR, Dann P, Zhang JP, Harris S, Robinson GW, Wysolmerski J: BMP4 and PTHrP interact to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction. Development. 2007 Mar; 2007 Feb 14. PMID: 17301089

Samuel VT, Liu ZX, Wang A, Beddow SA, Geisler JG, Kahn M, Zhang XM, Monia BP, Bhanot S, Shulman GI: Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease. J Clin Invest. 2007 Mar; 2007 Feb 22. PMID: 17318260

Manes TD, Shiao SL, Dengler TJ, Pober JS: TCR signaling antagonizes rapid IP-10-mediated transendothelial migration of effector memory CD4+ T cells. J Immunol. 2007 Mar 1. PMID: 17312172

Johung K, Goodwin EC, DiMaio D: Human papillomavirus E7 repression in cervical carcinoma cells initiates a transcriptional cascade driven by the retinoblastoma family, resulting in senescence. J Virol. 2007 Mar; 2006 Dec 20. PMID: 17182682

Ebersbach G, Jacobs-Wagner C: Exploration into the spatial and temporal mechanisms of bacterial polarity. Trends Microbiol. 2007 Mar; 2007 Feb 1. PMID: 17275310

Yohannan S, Hu Y, Zhou Y: Crystallographic study of the tetrabutylammonium block to the KcsA K+ channel. J Mol Biol. 2007 Feb 23; 2006 Dec 2. PMID: 17196615

Srivastava A, Pastor-Pareja JC, Igaki T, Pagliarini R, Xu T: Basement membrane remodeling is essential for Drosophila disc eversion and tumor invasion. Proc Natl Acad Sci U S A. 2007 Feb 20; 2007 Feb 14. PMID: 17301221

Chen R, Alvero AB, Silasi DA, Mor G: Inflammation, cancer and chemoresistance: taking advantage of the toll-like receptor signaling pathway. Am J Reprod Immunol. 2007 Feb. PMID: 17217363

Round J, Stein E: Netrin signaling leading to directed growth cone steering. Curr Opin Neurobiol. 2007 Feb; 2007 Jan 24. PMID: 17254765

Murray TS, Egan M, Kazmierczak BI: Pseudomonas aeruginosa chronic colonization in cystic fibrosis patients. Curr Opin Pediatr. 2007 Feb. PMID: 17224667

Stocco C, Telleria C, Gibori G: The molecular control of corpus luteum formation, function, and regression. Endocr Rev. 2007 Feb; 2006 Oct 31. PMID: 17077191

Zhang JJ, Kelm RJ, Biswas P, Kashgarian M, Madri JA: PECAM-1 modulates thrombin-induced tissue factor expression on endothelial cells. J Cell Physiol. 2007 Feb. PMID: 17111362

Chao D, Donnelly DF, Feng Y, Bazzy-Asaad A, Xia Y: Cortical delta-opioid receptors potentiate K+ homeostasis during anoxia and oxygen-glucose deprivation. J Cereb Blood Flow Metab. 2007 Feb; 2006 Jun 14. PMID: 16773140

Schmidt EF, Strittmatter SM: The CRMP family of proteins and their role in Sema3A signaling. Adv Exp Med Biol. 2007. PMID: 17607942

Hashmi AZ, Hakim W, Kruglov EA, Watanabe A, Watkins W, Dranoff JA, Mehal WZ: Adenosine inhibits cytosolic calcium signals and chemotaxis in hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol. 2007 Jan; 2006 Oct 19. PMID: 17053161

Tanis KQ, Duman RS: Intracellular signaling pathways pave roads to recovery for mood disorders. Ann Med. 2007. PMID: 17852035

Bordey A: Enigmatic GABAergic networks in adult neurogenic zones. Brain Res Rev. 2007 Jan; 2006 Sep 1. PMID: 16949673

Stopper GF, Wagner GP: Inhibition of Sonic hedgehog signaling leads to posterior digit loss in Ambystoma mexicanum: parallels to natural digit reduction in urodeles. Dev Dyn. 2007 Jan. PMID: 17117438

Lei H, Juan AH, Kim MS, Ruddle FH: Mouse naked cuticle 2 (mNkd2) as a direct transcriptional target of Hoxc8 in vivo. J Exp Zool A Ecol Genet Physiol. 2007 Jan 1. PMID: 17094106

Liu ZW, Gao XB: Adenosine inhibits activity of hypocretin/orexin neurons by the A1 receptor in the lateral hypothalamus: a possible sleep-promoting effect. J Neurophysiol. 2007 Jan; 2006 Nov 8. PMID: 17093123

Shu Y, Duque A, Yu Y, Haider B, McCormick DA: Properties of action-potential initiation in neocortical pyramidal cells: evidence from whole cell axon recordings. J Neurophysiol. 2007 Jan; 2006 Nov 8. PMID: 17093120

Zhang C, Marek GJ: Group III metabotropic glutamate receptor agonists selectively suppress excitatory synaptic currents in the rat prefrontal cortex induced by 5-hydroxytryptamine2A receptor activation. J Pharmacol Exp Ther. 2007 Jan; 2006 Oct 4. PMID: 17021259

Gao Q, Mezei G, Nie Y, Rao Y, Choi CS, Bechmann I, Leranth C, Toran-Allerand D, Priest CA, Roberts JL, Gao XB, Mobbs C, Shulman GI, Diano S, Horvath TL: Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals. Nat Med. 2007 Jan; 2006 Dec 31. PMID: 17195839

Ornstein DL, Zacharski LR: Iron stimulates urokinase plasminogen activator expression and activates NF-kappa B in human prostate cancer cells. Nutr Cancer. 2007. PMID: 17571974

Jordt SE, Ehrlich BE: TRP channels in disease. Subcell Biochem. 2007. PMID: 18193640

Conrad NK, Mili S, Marshall EL, Shu MD, Steitz JA: Identification of a rapid mammalian deadenylation-dependent decay pathway and its inhibition by a viral RNA element. Mol Cell. 2006 Dec 28. PMID: 17189195

Hayden MS, West AP, Ghosh S: SnapShot: NF-kappaB signaling pathways. Cell. 2006 Dec 15. PMID: 17174900

Sarkisian MR, Bartley CM, Chi H, Nakamura F, Hashimoto-Torii K, Torii M, Flavell RA, Rakic P: MEKK4 signaling regulates filamin expression and neuronal migration. Neuron. 2006 Dec 7. PMID: 17145501

Eswarakumar VP, Ozcan F, Lew ED, Bae JH, Tomé F, Booth CJ, Adams DJ, Lax I, Schlessinger J: Attenuation of signaling pathways stimulated by pathologically activated FGF-receptor 2 mutants prevents craniosynostosis. Proc Natl Acad Sci U S A. 2006 Dec 5; 2006 Nov 28. PMID: 17132737

Yip KY, Yu H, Kim PM, Schultz M, Gerstein M: The tYNA platform for comparative interactomics: a web tool for managing, comparing and mining multiple networks. Bioinformatics. 2006 Dec 1; 2006 Oct 4. PMID: 17021160

Sakai H, Chen Y, Itokawa T, Yu KP, Zhu ML, Insogna K: Activated c-Fms recruits Vav and Rac during CSF-1-induced cytoskeletal remodeling and spreading in osteoclasts. Bone. 2006 Dec; 2006 Sep 1. PMID: 16950670

Moriarty K, Kim KH, Bender JR: Minireview: estrogen receptor-mediated rapid signaling. Endocrinology. 2006 Dec; 2006 Aug 31. PMID: 16946015

Luna C, Hoa NT, Lin H, Zhang L, Nguyen HL, Kanzok SM, Zheng L: Expression of immune responsive genes in cell lines from two different Anopheline species. Insect Mol Biol. 2006 Dec. PMID: 17201765

Ishibe S, Haydu JE, Togawa A, Marlier A, Cantley LG: Cell confluence regulates hepatocyte growth factor-stimulated cell morphogenesis in a beta-catenin-dependent manner. Mol Cell Biol. 2006 Dec; 2006 Oct 9. PMID: 17030602

Cleary MA, Uboha N, Picciotto MR, Beech RD: Expression of ezrin in glial tubes in the adult subventricular zone and rostral migratory stream. Neuroscience. 2006 Dec; 2006 Sep 22. PMID: 16996217

Goldstein DR: Toll like receptors and acute allograft rejection. Transpl Immunol. 2006 Dec; 2006 Oct 10. PMID: 17157206

Pedraza-Fariña LG: Mechanisms of oncogenic cooperation in cancer initiation and metastasis. Yale J Biol Med. 2006 Dec. PMID: 17940619

Boehmerle W, Splittgerber U, Lazarus MB, McKenzie KM, Johnston DG, Austin DJ, Ehrlich BE: Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism. Proc Natl Acad Sci U S A. 2006 Nov 28; 2006 Nov 17. PMID: 17114292

Choe CU, Ehrlich BE: The inositol 1,4,5-trisphosphate receptor (IP3R) and its regulators: sometimes good and sometimes bad teamwork. Sci STKE. 2006 Nov 28; 2006 Nov 28. PMID: 17132820

Lampert A, Dib-Hajj SD, Tyrrell L, Waxman SG: Size matters: Erythromelalgia mutation S241T in Nav1.7 alters channel gating. J Biol Chem. 2006 Nov 24; 2006 Sep 28. PMID: 17008310

Cafferty WB, Strittmatter SM: The Nogo-Nogo receptor pathway limits a spectrum of adult CNS axonal growth. J Neurosci. 2006 Nov 22. PMID: 17122049

Howe JR: Desensitization at the interface. ACS Chem Biol. 2006 Nov 21. PMID: 17168566

Lee JH, Deng XW, Kim WT: Possible role of light in the maintenance of EIN3/EIL1 stability in Arabidopsis seedlings. Biochem Biophys Res Commun. 2006 Nov 17; 2006 Sep 25. PMID: 17011517

Leacock SW, Reinke V: Expression profiling of MAP kinase-mediated meiotic progression in Caenorhabditis elegans. PLoS Genet. 2006 Nov 10. PMID: 17096596

Matthews EE, Zoonens M, Engelman DM: Dynamic helix interactions in transmembrane signaling. Cell. 2006 Nov 3. PMID: 17081964

Luo D, Luo Y, He Y, Zhang H, Zhang R, Li X, Dobrucki WL, Sinusas AJ, Sessa WC, Min W: Differential functions of tumor necrosis factor receptor 1 and 2 signaling in ischemia-mediated arteriogenesis and angiogenesis. Am J Pathol. 2006 Nov. PMID: 17071609

Weidhaas JB, Eisenmann DM, Holub JM, Nallur SV: A conserved RAS/mitogen-activated protein kinase pathway regulates DNA damage-induced cell death postirradiation in Radelegans. Cancer Res. 2006 Nov 1. PMID: 17079464

Schulze-Luehrmann J, Ghosh S: Antigen-receptor signaling to nuclear factor kappa B. Immunity. 2006 Nov. PMID: 17098202

Wu Y, Wang W, Richerson GB: The transmembrane sodium gradient influences ambient GABA concentration by altering the equilibrium of GABA transporters. J Neurophysiol. 2006 Nov; 2006 Jul 26. PMID: 16870837

Zhou Z, Xiong W, Masurkar AV, Chen WR, Shepherd GM: Dendritic calcium plateau potentials modulate input-output properties of juxtaglomerular cells in the rat olfactory bulb. J Neurophysiol. 2006 Nov; 2006 Jul 19. PMID: 16855116

Ramos BP, Stark D, Verduzco L, van Dyck CH, Arnsten AF: Alpha2A-adrenoceptor stimulation improves prefrontal cortical regulation of behavior through inhibition of cAMP signaling in aging animals. Learn Mem. 2006 Nov-Dec; 2006 Nov 13. PMID: 17101879

Bradley WD, Hernández SE, Settleman J, Koleske AJ: Integrin signaling through Arg activates p190RhoGAP by promoting its binding to p120RasGAP and recruitment to the membrane. Mol Biol Cell. 2006 Nov; 2006 Sep 13. PMID: 16971514

Badou A, Jha MK, Matza D, Mehal WZ, Freichel M, Flockerzi V, Flavell RA: Critical role for the beta regulatory subunits of Cav channels in T lymphocyte function. Proc Natl Acad Sci U S A. 2006 Oct 17; 2006 Oct 6. PMID: 17028169

Walker WE, Nasr IW, Camirand G, Tesar BM, Booth CJ, Goldstein DR: Absence of innate MyD88 signaling promotes inducible allograft acceptance. J Immunol. 2006 Oct 15. PMID: 17015716

Di Paolo G, De Camilli P: Phosphoinositides in cell regulation and membrane dynamics. Nature. 2006 Oct 12. PMID: 17035995

Fornaro M, Burch PM, Yang W, Zhang L, Hamilton CE, Kim JH, Neel BG, Bennett AM: SHP-2 activates signaling of the nuclear factor of activated T cells to promote skeletal muscle growth. J Cell Biol. 2006 Oct 9; 2006 Oct 2. PMID: 17015617

Schlessinger J, Lemmon MA: Nuclear signaling by receptor tyrosine kinases: the first robin of spring. Cell. 2006 Oct 6. PMID: 17018275

Shi X, Leng L, Wang T, Wang W, Du X, Li J, McDonald C, Chen Z, Murphy JW, Lolis E, Noble P, Knudson W, Bucala R: CD44 is the signaling component of the macrophage migration inhibitory factor-CD74 receptor complex. Immunity. 2006 Oct. PMID: 17045821

Faustino EV, Donnelly DF: An important functional role of persistent Na+ current in carotid body hypoxia transduction. J Appl Physiol (1985). 2006 Oct; 2006 Jun 15. PMID: 16778007

Shiah HS, Gao W, Baker DC, Cheng YC: Inhibition of cell growth and nuclear factor-kappaB activity in pancreatic cancer cell lines by a tylophorine analogue, DCB-3503. Mol Cancer Ther. 2006 Oct. PMID: 17041092

Kaczmarek LK: Non-conducting functions of voltage-gated ion channels. Nat Rev Neurosci. 2006 Oct. PMID: 16988652

Ptacek J, Snyder M: Charging it up: global analysis of protein phosphorylation. Trends Genet. 2006 Oct; 2006 Sep 5. PMID: 16908088

Liu BP, Cafferty WB, Budel SO, Strittmatter SM: Extracellular regulators of axonal growth in the adult central nervous system. Philos Trans R Soc Lond B Biol Sci. 2006 Sep 29. PMID: 16939977

Abizaid A, Gao Q, Horvath TL: Thoughts for food: brain mechanisms and peripheral energy balance. Neuron. 2006 Sep 21. PMID: 16982416

Tran EH, Azuma YT, Chen M, Weston C, Davis RJ, Flavell RA: Inactivation of JNK1 enhances innate IL-10 production and dampens autoimmune inflammation in the brain. Proc Natl Acad Sci U S A. 2006 Sep 5; 2006 Aug 28. PMID: 16938889

Zhang Y, Yeh JR, Mara A, Ju R, Hines JF, Cirone P, Griesbach HL, Schneider I, Slusarski DC, Holley SA, Crews CM: A chemical and genetic approach to the mode of action of fumagillin. Chem Biol. 2006 Sep. PMID: 16984890

Wang T: Flow-activated transport events along the nephron. Curr Opin Nephrol Hypertens. 2006 Sep. PMID: 16914967

Zhou Z, Xiong W, Zeng S, Xia A, Shepherd GM, Greer CA, Chen WR: Dendritic excitability and calcium signalling in the mitral cell distal glomerular tuft. Eur J Neurosci. 2006 Sep. PMID: 17004926

Stetson DB, Medzhitov R: Type I interferons in host defense. Immunity. 2006 Sep. PMID: 16979569

Li MO, Sanjabi S, Flavell RA: Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms. Immunity. 2006 Sep. PMID: 16973386

Kriegel MA, Tretter T, Blank N, Schiller M, Gabler C, Winkler S, Kalden JR, Lorenz HM: Interleukin-4 supports interleukin-12-induced proliferation and interferon-gamma secretion in human activated lymphoblasts and T helper type 1 cells. Immunology. 2006 Sep; 2006 Jun 6. PMID: 16762027

Estrada M, Varshney A, Ehrlich BE: Elevated testosterone induces apoptosis in neuronal cells. J Biol Chem. 2006 Sep 1; 2006 Jun 27. PMID: 16803879

Zhang W, Robert A, Vogensen SB, Howe JR: The relationship between agonist potency and AMPA receptor kinetics. Biophys J. 2006 Aug 15; 2006 May 26. PMID: 16731549

Swan LE, Schmidt M, Schwarz T, Ponimaskin E, Prange U, Boeckers T, Thomas U, Sigrist SJ: Complex interaction of Drosophila GRIP PDZ domains and Echinoid during muscle morphogenesis. EMBO J. 2006 Aug 9; 2006 Jul 20. PMID: 16858411

Pepperell JR, Nemeth G, Yamada Y, Naftolin F, Merino M: Localized accumulation of angiotensin II and production of angiotensin-(1-7) in rat luteal cells and effects on steroidogenesis. Am J Physiol Endocrinol Metab. 2006 Aug; 2006 Feb 14. PMID: 16478781

Zhou Y, Bouyer P, Boron WF: Role of a tyrosine kinase in the CO2-induced stimulation of HCO3- reabsorption by rabbit S2 proximal tubules. Am J Physiol Renal Physiol. 2006 Aug; 2006 May 16. PMID: 16705143

Jiang D, Liang J, Li Y, Noble PW: The role of Toll-like receptors in non-infectious lung injury. Cell Res. 2006 Aug. PMID: 16894359

Rakoff-Nahoum S, Hao L, Medzhitov R: Role of toll-like receptors in spontaneous commensal-dependent colitis. Immunity. 2006 Aug; 2006 Aug 3. PMID: 16879997

Laskowski MA, Kazmierczak BI: Mutational analysis of RetS, an unusual sensor kinase-response regulator hybrid required for Pseudomonas aeruginosa virulence. Infect Immun. 2006 Aug. PMID: 16861632

Bourne J, Morgan JR, Pieribone VA: Actin polymerization regulates clathrin coat maturation during early stages of synaptic vesicle recycling at lamprey synapses. J Comp Neurol. 2006 Aug 1. PMID: 16739194

Jonas E: BCL-xL regulates synaptic plasticity. Mol Interv. 2006 Aug. PMID: 16960143

Wan YY, Chi H, Xie M, Schneider MD, Flavell RA: The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function. Nat Immunol. 2006 Aug; 2006 Jun 25. PMID: 16799562

Tamarkin FJ, Kang WS, Cohen JJ, Wheeler MA, Weiss RM: A role for Akt in the rapid regulation of inflammatory and apoptotic pathways in mouse bladder. Naunyn Schmiedebergs Arch Pharmacol. 2006 Aug; 2006 Jul 11. PMID: 16832691

Lambe EK, Aghajanian GK: Hallucinogen-induced UP states in the brain slice of rat prefrontal cortex: role of glutamate spillover and NR2B-NMDA receptors. Neuropsychopharmacology. 2006 Aug; 2005 Nov 2. PMID: 16292328

Cambronne ED, Roy CR: Recognition and delivery of effector proteins into eukaryotic cells by bacterial secretion systems. Traffic. 2006 Aug; 2006 May 25. PMID: 16734660

Arteaga MF, Wang L, Ravid T, Hochstrasser M, Canessa CM: An amphipathic helix targets serum and glucocorticoid-induced kinase 1 to the endoplasmic reticulum-associated ubiquitin-conjugation machinery. Proc Natl Acad Sci U S A. 2006 Jul 25; 2006 Jul 17. PMID: 16847254

Holley SA: Anterior-posterior differences in vertebrate segments: specification of trunk and tail somites in the zebrafish blastula. Genes Dev. 2006 Jul 15. PMID: 16847343

Koelle MR: Heterotrimeric G protein signaling: Getting inside the cell. Cell. 2006 Jul 14. PMID: 16839871

Ghosh S, Choritz L, Geibel J, Coca-Prados M: Somatostatin modulates PI3K-Akt, eNOS and NHE activity in the ciliary epithelium. Mol Cell Endocrinol. 2006 Jul 11; 2006 Jun 9. PMID: 16764985

Allen PB, Zachariou V, Svenningsson P, Lepore AC, Centonze D, Costa C, Rossi S, Bender G, Chen G, Feng J, Snyder GL, Bernardi G, Nestler EJ, Yan Z, Calabresi P, Greengard P: Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity. Neuroscience. 2006 Jul 7. PMID: 16600521

Grabner C, Zenisek D: Rustling synaptic vesicle cargo after exocytosis. Neuron. 2006 Jul 6. PMID: 16815324

Biswas P, Canosa S, Schoenfeld D, Schoenfeld J, Li P, Cheas LC, Zhang J, Cordova A, Sumpio B, Madri JA: PECAM-1 affects GSK-3beta-mediated beta-catenin phosphorylation and degradation. Am J Pathol. 2006 Jul. PMID: 16816383

Brekke JF, Jackson WF, Segal SS: Arteriolar smooth muscle Ca2+ dynamics during blood flow control in hamster cheek pouch. J Appl Physiol (1985). 2006 Jul; 2006 Feb 2. PMID: 16455810

Galisteo ML, Yang Y, Ureña J, Schlessinger J: Activation of the nonreceptor protein tyrosine kinase Ack by multiple extracellular stimuli. Proc Natl Acad Sci U S A. 2006 Jun 27; 2006 Jun 15. PMID: 16777958

Minagawa N, Ehrlich BE, Nathanson MH: Calcium signaling in cholangiocytes. World J Gastroenterol. 2006 Jun 14. PMID: 16773703

Dimitrov P, Zucker SW: A constant production hypothesis guides leaf venation patterning. Proc Natl Acad Sci U S A. 2006 Jun 13; 2006 Jun 5. PMID: 16754846

Shu Y, Hasenstaub A, Duque A, Yu Y, McCormick DA: Modulation of intracortical synaptic potentials by presynaptic somatic membrane potential. Nature. 2006 Jun 8; 2006 Apr 12. PMID: 16625207

Igaki T, Pagliarini RA, Xu T: Loss of cell polarity drives tumor growth and invasion through JNK activation in Drosophila. Curr Biol. 2006 Jun 6. PMID: 16753569

Kagan JC, Medzhitov R: Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling. Cell. 2006 Jun 2. PMID: 16751103

Kwintkiewicz J, Spaczynski RZ, Foyouzi N, Pehlivan T, Duleba AJ: Insulin and oxidative stress modulate proliferation of rat ovarian theca-interstitial cells through diverse signal transduction pathways. Biol Reprod. 2006 Jun; 2006 Feb 15. PMID: 16481589

Archer KA, Roy CR: MyD88-dependent responses involving toll-like receptor 2 are important for protection and clearance of Legionella pneumophila in a mouse model of Legionnaires' disease. Infect Immun. 2006 Jun. PMID: 16714560

Leckman JF, Vaccarino FM, Kalanithi PS, Rothenberger A: Annotation: Tourette syndrome: a relentless drumbeat--driven by misguided brain oscillations. J Child Psychol Psychiatry. 2006 Jun. PMID: 16712630

Seval Y, Cakmak H, Kayisli UA, Arici A: Estrogen-mediated regulation of p38 mitogen-activated protein kinase in human endometrium. J Clin Endocrinol Metab. 2006 Jun; 2006 Mar 7. PMID: 16522698

Schlecker C, Boehmerle W, Jeromin A, DeGray B, Varshney A, Sharma Y, Szigeti-Buck K, Ehrlich BE: Neuronal calcium sensor-1 enhancement of InsP3 receptor activity is inhibited by therapeutic levels of lithium. J Clin Invest. 2006 Jun; 2006 May 11. PMID: 16691292

Aoki K, Saito H, Itzstein C, Ishiguro M, Shibata T, Blanque R, Mian AH, Takahashi M, Suzuki Y, Yoshimatsu M, Yamaguchi A, Deprez P, Mollat P, Murali R, Ohya K, Horne WC, Baron R: A TNF receptor loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone loss. J Clin Invest. 2006 Jun; 2006 May 4. PMID: 16680194

Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM: Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun; 2006 May 21. PMID: 16715082

Bruzzaniti A, Baron R: Molecular regulation of osteoclast activity. Rev Endocr Metab Disord. 2006 Jun. PMID: 16951988

Rush AM, Dib-Hajj SD, Liu S, Cummins TR, Black JA, Waxman SG: A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons. Proc Natl Acad Sci U S A. 2006 May 23; 2006 May 15. PMID: 16702558

Togashi H, Schmidt EF, Strittmatter SM: RanBPM contributes to Semaphorin3A signaling through plexin-A receptors. J Neurosci. 2006 May 3. PMID: 16672672

Tuck DP, Kluger HM, Kluger Y: Characterizing disease states from topological properties of transcriptional regulatory networks. BMC Bioinformatics. 2006 May 2; 2006 May 2. PMID: 16670008

Simen BB, Duman CH, Simen AA, Duman RS: TNFalpha signaling in depression and anxiety: behavioral consequences of individual receptor targeting. Biol Psychiatry. 2006 May 1; 2006 Feb 3. PMID: 16458261

Carrillo-Vico A, Reiter RJ, Lardone PJ, Herrera JL, Fernández-Montesinos R, Guerrero JM, Pozo D: The modulatory role of melatonin on immune responsiveness. Curr Opin Investig Drugs. 2006 May. PMID: 16729718

Czopik AK, Bynoe MS, Palm N, Raine CS, Medzhitov R: Semaphorin 7A is a negative regulator of T cell responses. Immunity. 2006 May. PMID: 16713976

Du W, Wong FS, Li MO, Peng J, Qi H, Flavell RA, Sherwin R, Wen L: TGF-beta signaling is required for the function of insulin-reactive T regulatory cells. J Clin Invest. 2006 May. PMID: 16670772

Yu J, Bergaya S, Murata T, Alp IF, Bauer MP, Lin MI, Drab M, Kurzchalia TV, Stan RV, Sessa WC: Direct evidence for the role of caveolin-1 and caveolae in mechanotransduction and remodeling of blood vessels. J Clin Invest. 2006 May. PMID: 16670769

Ramana CV, Chintapalli J, Xu L, Alia C, Zhou J, Bruder D, Enelow RI: Lung epithelial NF-kappaB and Stat1 signaling in response to CD8+ T cell antigen recognition. J Interferon Cytokine Res. 2006 May. PMID: 16689660

Khanna-Gupta A, Sun H, Zibello T, Lozovatsky L, Ghosh PK, Link DC, McLemore ML, Berliner N: p120 nucleolar-proliferating antigen is a direct target of G-CSF signaling during myeloid differentiation. J Leukoc Biol. 2006 May. PMID: 16641140

Biemesderfer D: Regulated intramembrane proteolysis of megalin: linking urinary protein and gene regulation in proximal tubule? Kidney Int. 2006 May. PMID: 16557231

Williams GV, Castner SA: Under the curve: critical issues for elucidating D1 receptor function in working memory. Neuroscience. 2006 Apr 28; 2005 Nov 28. PMID: 16310964

Haider B, Duque A, Hasenstaub AR, McCormick DA: Neocortical network activity in vivo is generated through a dynamic balance of excitation and inhibition. J Neurosci. 2006 Apr 26. PMID: 16641233

Ma B, Liu W, Homer RJ, Lee PJ, Coyle AJ, Lora JM, Lee CG, Elias JA: Role of CCR5 in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol. 2006 Apr 15. PMID: 16585593

Bergsman JB, Krueger SR, Fitzsimonds RM: Automated criteria-based selection and analysis of fluorescent synaptic puncta. J Neurosci Methods. 2006 Apr 15; 2005 Sep 28. PMID: 16198002

Kelly MG, Alvero AB, Chen R, Silasi DA, Abrahams VM, Chan S, Visintin I, Rutherford T, Mor G: TLR-4 signaling promotes tumor growth and paclitaxel chemoresistance in ovarian cancer. Cancer Res. 2006 Apr 1. PMID: 16585214

Bordey A: Adult neurogenesis: basic concepts of signaling. Cell Cycle. 2006 Apr; 2006 Apr 1. PMID: 16582623

Wan L, Cao D, Zeng J, Yan R, Pizzorno G: Modulation of uridine phosphorylase gene expression by tumor necrosis factor-alpha enhances the antiproliferative activity of the capecitabine intermediate 5'-deoxy-5-fluorouridine in breast cancer cells. Mol Pharmacol. 2006 Apr; 2006 Jan 5. PMID: 16397116

Shim JH, Xiao C, Hayden MS, Lee KY, Trombetta ES, Pypaert M, Nara A, Yoshimori T, Wilm B, Erdjument-Bromage H, Tempst P, Hogan BL, Mellman I, Ghosh S: CHMP5 is essential for late endosome function and down-regulation of receptor signaling during mouse embryogenesis. J Cell Biol. 2006 Mar 27. PMID: 16567502

Su CY, Luo DG, Terakita A, Shichida Y, Liao HW, Kazmi MA, Sakmar TP, Yau KW: Parietal-eye phototransduction components and their potential evolutionary implications. Science. 2006 Mar 17. PMID: 16543463

Wendler CC, Rivkees SA: Sphingosine-1-phosphate inhibits cell migration and endothelial to mesenchymal cell transformation during cardiac development. Dev Biol. 2006 Mar 15; 2006 Jan 23. PMID: 16434032

He Y, Zhang W, Zhang R, Zhang H, Min W: SOCS1 inhibits tumor necrosis factor-induced activation of ASK1-JNK inflammatory signaling by mediating ASK1 degradation. J Biol Chem. 2006 Mar 3; 2006 Jan 5. PMID: 16407264

Gascón JA, Sproviero EM, Batista VS: Computational studies of the primary phototransduction event in visual rhodopsin. Acc Chem Res. 2006 Mar. PMID: 16548507

Zhou Y, Bouyer P, Boron WF: Effects of angiotensin II on the CO2 dependence of HCO3- reabsorption by the rabbit S2 renal proximal tubule. Am J Physiol Renal Physiol. 2006 Mar; 2005 Oct 4. PMID: 16204407

Savage DB, Choi CS, Samuel VT, Liu ZX, Zhang D, Wang A, Zhang XM, Cline GW, Yu XX, Geisler JG, Bhanot S, Monia BP, Shulman GI: Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2. J Clin Invest. 2006 Mar; 2006 Feb 16. PMID: 16485039

Canitano R: Self injurious behavior in autism: clinical aspects and treatment with risperidone. J Neural Transm (Vienna). 2006 Mar; 2005 Aug 3. PMID: 16075185

Vucinić D, Cohen LB, Kosmidis EK: Interglomerular center-surround inhibition shapes odorant-evoked input to the mouse olfactory bulb in vivo. J Neurophysiol. 2006 Mar; 2005 Nov 30. PMID: 16319205

Zamboni DS, Kobayashi KS, Kohlsdorf T, Ogura Y, Long EM, Vance RE, Kuida K, Mariathasan S, Dixit VM, Flavell RA, Dietrich WF, Roy CR: The Birc1e cytosolic pattern-recognition receptor contributes to the detection and control of Legionella pneumophila infection. Nat Immunol. 2006 Mar; 2006 Jan 29. PMID: 16444259

Diano S, Farr SA, Benoit SC, McNay EC, da Silva I, Horvath B, Gaskin FS, Nonaka N, Jaeger LB, Banks WA, Morley JE, Pinto S, Sherwin RS, Xu L, Yamada KA, Sleeman MW, Tschöp MH, Horvath TL: Ghrelin controls hippocampal spine synapse density and memory performance. Nat Neurosci. 2006 Mar; 2006 Feb 19. PMID: 16491079

Czyzyk J: The role of Toll-like receptors in the pathogenesis of renal disease. Semin Nephrol. 2006 Mar. PMID: 16530608

Estrada M, Uhlen P, Ehrlich BE: Ca2+ oscillations induced by testosterone enhance neurite outgrowth. J Cell Sci. 2006 Feb 15; 2006 Jan 31. PMID: 16449326

William J, Euler C, Primarolo N, Shlomchik MJ: B cell tolerance checkpoints that restrict pathways of antigen-driven differentiation. J Immunol. 2006 Feb 15. PMID: 16455970

Uhlén P, Burch PM, Zito CI, Estrada M, Ehrlich BE, Bennett AM: Gain-of-function/Noonan syndrome SHP-2/Ptpn11 mutants enhance calcium oscillations and impair NFAT signaling. Proc Natl Acad Sci U S A. 2006 Feb 14; 2006 Feb 3. PMID: 16461457

El-Guindy AS, Paek SY, Countryman J, Miller G: Identification of constitutive phosphorylation sites on the Epstein-Barr virus ZEBRA protein. J Biol Chem. 2006 Feb 10; 2005 Dec 1. PMID: 16321978

Ravid T, Kreft SG, Hochstrasser M: Membrane and soluble substrates of the Doa10 ubiquitin ligase are degraded by distinct pathways. EMBO J. 2006 Feb 8; 2006 Jan 26. PMID: 16437165

Leng Q, MacGregor GG, Dong K, Giebisch G, Hebert SC: Subunit-subunit interactions are critical for proton sensitivity of ROMK: evidence in support of an intermolecular gating mechanism. Proc Natl Acad Sci U S A. 2006 Feb 7; 2006 Jan 30. PMID: 16446432

Li Y, Wang P, Xu J, Desir GV: Voltage-gated potassium channel Kv1.3 regulates GLUT4 trafficking to the plasma membrane via a Ca2+-dependent mechanism. Am J Physiol Cell Physiol. 2006 Feb. PMID: 16403947

Leng L, Bucala R: Insight into the biology of macrophage migration inhibitory factor (MIF) revealed by the cloning of its cell surface receptor. Cell Res. 2006 Feb. PMID: 16474429

Zhang P, Sigworth FJ, Canessa CM: Gating of acid-sensitive ion channel-1: release of Ca2+ block vs. allosteric mechanism. J Gen Physiol. 2006 Feb; 2006 Jan 17. PMID: 16418400

Tan ZY, Donnelly DF, LaMotte RH: Effects of a chronic compression of the dorsal root ganglion on voltage-gated Na+ and K+ currents in cutaneous afferent neurons. J Neurophysiol. 2006 Feb. PMID: 16424456

Louvi A, Artavanis-Tsakonas S: Notch signalling in vertebrate neural development. Nat Rev Neurosci. 2006 Feb. PMID: 16429119

Seker A, Pricola KL, Guclu B, Ozturk AK, Louvi A, Gunel M: CCM2 expression parallels that of CCM1. Stroke. 2006 Feb; 2005 Dec 22. PMID: 16373645

Grosshans BL, Andreeva A, Gangar A, Niessen S, Yates JR 3rd, Brennwald P, Novick P: The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p. J Cell Biol. 2006 Jan 2. PMID: 16390997

West AP, Koblansky AA, Ghosh S: Recognition and signaling by toll-like receptors. Annu Rev Cell Dev Biol. 2006. PMID: 16822173

Kerscher O, Felberbaum R, Hochstrasser M: Modification of proteins by ubiquitin and ubiquitin-like proteins. Annu Rev Cell Dev Biol. 2006. PMID: 16753028

Li MO, Wan YY, Sanjabi S, Robertson AK, Flavell RA: Transforming growth factor-beta regulation of immune responses. Annu Rev Immunol. 2006. PMID: 16551245

Marius P, Guerra MT, Nathanson MH, Ehrlich BE, Leite MF: Calcium release from ryanodine receptors in the nucleoplasmic reticulum. Cell Calcium. 2006 Jan; 2005 Nov 9. PMID: 16289270

Baron R, Rawadi G, Roman-Roman S: Wnt signaling: a key regulator of bone mass. Curr Top Dev Biol. 2006. PMID: 17118265

Louvi A, Arboleda-Velasquez JF, Artavanis-Tsakonas S: CADASIL: a critical look at a Notch disease. Dev Neurosci. 2006. PMID: 16508299

Kadohama T, Akasaka N, Nishimura K, Hoshino Y, Sasajima T, Sumpio BE: p38 Mitogen-activated protein kinase activation in endothelial cell is implicated in cell alignment and elongation induced by fluid shear stress. Endothelium. 2006 Jan-Feb. PMID: 16885066

Pober JS, Min W: Endothelial cell dysfunction, injury and death. Handb Exp Pharmacol. 2006. PMID: 16999227

Asaka Y, Jugloff DG, Zhang L, Eubanks JH, Fitzsimonds RM: Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome. Neurobiol Dis. 2006 Jan; 2005 Aug 8. PMID: 16087343

Cheries EW, Newman GE, Santos LR, Scholl BJ: Units of visual individuation in rhesus macaques: objects or unbound features? Perception. 2006. PMID: 17076066

Choi H, Scholl BJ: Perceiving causality after the fact: postdiction in the temporal dynamics of causal perception. Perception. 2006. PMID: 16619953

van Duin D, Medzhitov R, Shaw AC: Triggering TLR signaling in vaccination. Trends Immunol. 2006 Jan; 2005 Nov 23. PMID: 16310411

Boehm M, Slack F: A developmental timing microRNA and its target regulate life span in C. elegans. Science. 2005 Dec 23. PMID: 16373574

Gibson SL, Bindra RS, Glazer PM: Hypoxia-induced phosphorylation of Chk2 in an ataxia telangiectasia mutated-dependent manner. Cancer Res. 2005 Dec 1. PMID: 16322218

Horne WC, Sanjay A, Bruzzaniti A, Baron R: The role(s) of Src kinase and Cbl proteins in the regulation of osteoclast differentiation and function. Immunol Rev. 2005 Dec. PMID: 16313344

Morino K, Petersen KF, Dufour S, Befroy D, Frattini J, Shatzkes N, Neschen S, White MF, Bilz S, Sono S, Pypaert M, Shulman GI: Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents. J Clin Invest. 2005 Dec; 2005 Nov 10. PMID: 16284649

Migliore M, Ferrante M, Ascoli GA: Signal propagation in oblique dendrites of CA1 pyramidal cells. J Neurophysiol. 2005 Dec. PMID: 16293591

Pawelek JM: Tumour-cell fusion as a source of myeloid traits in cancer. Lancet Oncol. 2005 Dec. PMID: 16321767

Brodsky IE, Gunn JS: A bacterial sensory system that activates resistance to innate immune defenses: potential targets for antimicrobial therapeutics. Mol Interv. 2005 Dec. PMID: 16394247

Pasare C, Medzhitov R: Control of B-cell responses by Toll-like receptors. Nature. 2005 Nov 17. PMID: 16292312

Shim JH, Xiao C, Paschal AE, Bailey ST, Rao P, Hayden MS, Lee KY, Bussey C, Steckel M, Tanaka N, Yamada G, Akira S, Matsumoto K, Ghosh S: TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo. Genes Dev. 2005 Nov 15; 2005 Oct 31. PMID: 16260493

Prum RO: Evolution of the morphological innovations of feathers. J Exp Zool B Mol Dev Evol. 2005 Nov 15. PMID: 16208685

Toomre D: Spying on IgE receptor signaling: simply complex, or not? J Cell Biol. 2005 Nov 7. PMID: 16275748

Ludwig T: Local proteolytic activity in tumor cell invasion and metastasis. Bioessays. 2005 Nov. PMID: 16237672

Navaratnam D, Bai JP, Samaranayake H, Santos-Sacchi J: N-terminal-mediated homomultimerization of prestin, the outer hair cell motor protein. Biophys J. 2005 Nov; 2005 Aug 19. PMID: 16113116

Sehgal S, Guerra MT, Kruglov EA, Wang J, Nathanson MH: Protein 4.1N does not interact with the inositol 1,4,5-trisphosphate receptor in an epithelial cell line. Cell Calcium. 2005 Nov. PMID: 16122796

Lai PC, Singer MS, Crasto CJ: Structural activation pathways from dynamic olfactory receptor-odorant interactions. Chem Senses. 2005 Nov; 2005 Oct 21. PMID: 16243965

Goldstein DR, Palmer SM: Role of Toll-like receptor-driven innate immunity in thoracic organ transplantation. J Heart Lung Transplant. 2005 Nov. PMID: 16297771

Shi WX: Slow oscillatory firing: a major firing pattern of dopamine neurons in the ventral tegmental area. J Neurophysiol. 2005 Nov. PMID: 16222075

Coric T, Zheng D, Gerstein M, Canessa CM: Proton sensitivity of ASIC1 appeared with the rise of fishes by changes of residues in the region that follows TM1 in the ectodomain of the channel. J Physiol. 2005 Nov 1; 2005 Jul 7. PMID: 16002453

Penchovsky R, Breaker RR: Computational design and experimental validation of oligonucleotide-sensing allosteric ribozymes. Nat Biotechnol. 2005 Nov; 2005 Oct 23. PMID: 16244657

Andrews ZB, Diano S, Horvath TL: Mitochondrial uncoupling proteins in the CNS: in support of function and survival. Nat Rev Neurosci. 2005 Nov. PMID: 16224498

Andrews NW, Chakrabarti S: There's more to life than neurotransmission: the regulation of exocytosis by synaptotagmin VII. Trends Cell Biol. 2005 Nov; 2005 Sep 15. PMID: 16168654

Patel JC, Rossanese OW, Galán JE: The functional interface between Salmonella and its host cell: opportunities for therapeutic intervention. Trends Pharmacol Sci. 2005 Nov; 2005 Sep 22. PMID: 16182381

Rivetta A, Slayman C, Kuroda T: Quantitative modeling of chloride conductance in yeast TRK potassium transporters. Biophys J. 2005 Oct; 2005 Jul 22. PMID: 16040756

Cooper AF, Yu KP, Brueckner M, Brailey LL, Johnson L, McGrath JM, Bale AE: Cardiac and CNS defects in a mouse with targeted disruption of suppressor of fused. Development. 2005 Oct. PMID: 16155214

Asada H, Paszkowiak J, Teso D, Alvi K, Thorisson A, Frattini JC, Kudo FA, Sumpio BE, Dardik A: Sustained orbital shear stress stimulates smooth muscle cell proliferation via the extracellular signal-regulated protein kinase 1/2 pathway. J Vasc Surg. 2005 Oct. PMID: 16242567

Soosaar JL, Burch-Smith TM, Dinesh-Kumar SP: Mechanisms of plant resistance to viruses. Nat Rev Microbiol. 2005 Oct. PMID: 16132037

Minagawa N, Kruglov EA, Dranoff JA, Robert ME, Gores GJ, Nathanson MH: The anti-apoptotic protein Mcl-1 inhibits mitochondrial Ca2+ signals. J Biol Chem. 2005 Sep 30; 2005 Jul 18. PMID: 16027162

McGee AW, Yang Y, Fischer QS, Daw NW, Strittmatter SM: Experience-driven plasticity of visual cortex limited by myelin and Nogo receptor. Science. 2005 Sep 30. PMID: 16195464

Zhang YW, Rudnick G: Cysteine-scanning mutagenesis of serotonin transporter intracellular loop 2 suggests an alpha-helical conformation. J Biol Chem. 2005 Sep 2; 2005 Jul 1. PMID: 15994310

Jonas EA, Hardwick JM, Kaczmarek LK: Actions of BAX on mitochondrial channel activity and on synaptic transmission. Antioxid Redox Signal. 2005 Sep-Oct. PMID: 16115013

Park SY, Cho YR, Finck BN, Kim HJ, Higashimori T, Hong EG, Lee MK, Danton C, Deshmukh S, Cline GW, Wu JJ, Bennett AM, Rothermel B, Kalinowski A, Russell KS, Kim YB, Kelly DP, Kim JK: Cardiac-specific overexpression of peroxisome proliferator-activated receptor-alpha causes insulin resistance in heart and liver. Diabetes. 2005 Sep. PMID: 16123338

Pedra JH, Sukumaran B, Carlyon JA, Berliner N, Fikrig E: Modulation of NB4 promyelocytic leukemic cell machinery by Anaplasma phagocytophilum. Genomics. 2005 Sep. PMID: 16005178

Chen WR, Shepherd GM: The olfactory glomerulus: a cortical module with specific functions. J Neurocytol. 2005 Sep; 2006 Jul 13. PMID: 16841172

Choi J, Walker J, Talbert-Slagle K, Wright P, Pober JS, Alexander L: Endothelial cells promote human immunodeficiency virus replication in nondividing memory T cells via Nef-, Vpr-, and T-cell receptor-dependent activation of NFAT. J Virol. 2005 Sep. PMID: 16103171

Karihaloo A, Karumanchi SA, Cantley WL, Venkatesha S, Cantley LG, Kale S: Vascular endothelial growth factor induces branching morphogenesis/tubulogenesis in renal epithelial cells in a neuropilin-dependent fashion. Mol Cell Biol. 2005 Sep. PMID: 16107693

Agaisse H, Burrack LS, Philips JA, Rubin EJ, Perrimon N, Higgins DE: Genome-wide RNAi screen for host factors required for intracellular bacterial infection. Science. 2005 Aug 19; 2005 Jul 14. PMID: 16020693

Anderson E, Maday S, Sfakianos J, Hull M, Winckler B, Sheff D, Fölsch H, Mellman I: Transcytosis of NgCAM in epithelial cells reflects differential signal recognition on the endocytic and secretory pathways. J Cell Biol. 2005 Aug 15; 2005 Aug 8. PMID: 16087710

Acuna-Goycolea C, Tamamaki N, Yanagawa Y, Obata K, van den Pol AN: Mechanisms of neuropeptide Y, peptide YY, and pancreatic polypeptide inhibition of identified green fluorescent protein-expressing GABA neurons in the hypothalamic neuroendocrine arcuate nucleus. J Neurosci. 2005 Aug 10. PMID: 16093392

Hasenstaub A, Shu Y, Haider B, Kraushaar U, Duque A, McCormick DA: Inhibitory postsynaptic potentials carry synchronized frequency information in active cortical networks. Neuron. 2005 Aug 4. PMID: 16055065

Liu Y, Liu N, Zhao H: Inferring protein-protein interactions through high-throughput interaction data from diverse organisms. Bioinformatics. 2005 Aug 1; 2005 May 19. PMID: 15905281

Wang CX, Koay DC, Edwards A, Lu Z, Mor G, Ocal IT, Digiovanna MP: In vitro and in vivo effects of combination of Trastuzumab (Herceptin) and Tamoxifen in breast cancer. Breast Cancer Res Treat. 2005 Aug. PMID: 16155796

Burtness B: The role of cetuximab in the treatment of squamous cell cancer of the head and neck. Expert Opin Biol Ther. 2005 Aug. PMID: 16050785

Stern DF: Phosphoproteomics for oncology discovery and treatment. Expert Opin Ther Targets. 2005 Aug. PMID: 16083347

Li JH, Pober JS: The cathepsin B death pathway contributes to TNF plus IFN-gamma-mediated human endothelial injury. J Immunol. 2005 Aug 1. PMID: 16034129

Nie Y, Ding L, Kao PN, Braun R, Yang JH: ADAR1 interacts with NF90 through double-stranded RNA and regulates NF90-mediated gene expression independently of RNA editing. Mol Cell Biol. 2005 Aug. PMID: 16055709

Seck T, Pellegrini M, Florea AM, Grignoux V, Baron R, Mierke DF, Horne WC: The delta e13 isoform of the calcitonin receptor forms a six-transmembrane domain receptor with dominant-negative effects on receptor surface expression and signaling. Mol Endocrinol. 2005 Aug; 2005 Apr 28. PMID: 15860547

Krendel M, Mooseker MS: Myosins: tails (and heads) of functional diversity. Physiology (Bethesda). 2005 Aug. PMID: 16024512

Abrahams VM, Mor G: Toll-like receptors and their role in the trophoblast. Placenta. 2005 Aug. PMID: 15993703

Fadiel A, Eichenbaum KD, Hamza A, Tuncalp O, Luk J, Naftolin F: Protein misfolding and misprocessing in complex disease. Protein Pept Lett. 2005 Aug. PMID: 16101385

Wittmack EK, Rush AM, Hudmon A, Waxman SG, Dib-Hajj SD: Voltage-gated sodium channel Nav1.6 is modulated by p38 mitogen-activated protein kinase. J Neurosci. 2005 Jul 13. PMID: 16014723

O'Connell AD, Leng Q, Dong K, MacGregor GG, Giebisch G, Hebert SC: Phosphorylation-regulated endoplasmic reticulum retention signal in the renal outer-medullary K+ channel (ROMK). Proc Natl Acad Sci U S A. 2005 Jul 12; 2005 Jun 29. PMID: 15987778

Schafe GE, Bauer EP, Rosis S, Farb CR, Rodrigues SM, LeDoux JE: Memory consolidation of Pavlovian fear conditioning requires nitric oxide signaling in the lateral amygdala. Eur J Neurosci. 2005 Jul. PMID: 16029210

Negyessy L, Goldman-Rakic PS: Morphometric characterization of synapses in the primate prefrontal cortex formed by afferents from the mediodorsal thalamic nucleus. Exp Brain Res. 2005 Jul; 2005 Mar 18. PMID: 15776222

Zhang SS, Liu MG, Kano A, Zhang C, Fu XY, Barnstable CJ: STAT3 activation in response to growth factors or cytokines participates in retina precursor proliferation. Exp Eye Res. 2005 Jul. PMID: 15978261

Kakisis JD, Pradhan S, Cordova A, Liapis CD, Sumpio BE: The role of STAT-3 in the mediation of smooth muscle cell response to cyclic strain. Int J Biochem Cell Biol. 2005 Jul. PMID: 15833272

Hens JR, Wilson KM, Dann P, Chen X, Horowitz MC, Wysolmerski JJ: TOPGAL mice show that the canonical Wnt signaling pathway is active during bone development and growth and is activated by mechanical loading in vitro. J Bone Miner Res. 2005 Jul; 2005 Feb 14. PMID: 15940363

Gascón JA, Sproviero EM, Batista VS: QM/MM Study of the NMR Spectroscopy of the Retinyl Chromophore in Visual Rhodopsin. J Chem Theory Comput. 2005 Jul. PMID: 26641690

Bruzzaniti A, Neff L, Sanjay A, Horne WC, De Camilli P, Baron R: Dynamin forms a Src kinase-sensitive complex with Cbl and regulates podosomes and osteoclast activity. Mol Biol Cell. 2005 Jul; 2005 May 4. PMID: 15872089

Jhandier MN, Kruglov EA, Lavoie EG, Sévigny J, Dranoff JA: Portal fibroblasts regulate the proliferation of bile duct epithelia via expression of NTPDase2. J Biol Chem. 2005 Jun 17; 2005 Mar 30. PMID: 15799977

Zheng T, Kang MJ, Crothers K, Zhu Z, Liu W, Lee CG, Rabach LA, Chapman HA, Homer RJ, Aldous D, De Sanctis GT, Underwood S, Graupe M, Flavell RA, Schmidt JA, Elias JA: Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysema. J Immunol. 2005 Jun 15. PMID: 15944319

Kim KH, Bender JR: Rapid, estrogen receptor-mediated signaling: why is the endothelium so special? Sci STKE. 2005 Jun 14; 2005 Jun 14. PMID: 15956360

Kim JK, Kim HJ, Park SY, Cederberg A, Westergren R, Nilsson D, Higashimori T, Cho YR, Liu ZX, Dong J, Cline GW, Enerback S, Shulman GI: Adipocyte-specific overexpression of FOXC2 prevents diet-induced increases in intramuscular fatty acyl CoA and insulin resistance. Diabetes. 2005 Jun. PMID: 15919786

Hawes JJ, Brunzell DH, Wynick D, Zachariou V, Picciotto MR: GalR1, but not GalR2 or GalR3, levels are regulated by galanin signaling in the locus coeruleus through a cyclic AMP-dependent mechanism. J Neurochem. 2005 Jun. PMID: 15934937

Laouar Y, Sutterwala FS, Gorelik L, Flavell RA: Transforming growth factor-beta controls T helper type 1 cell development through regulation of natural killer cell interferon-gamma. Nat Immunol. 2005 Jun; 2005 Apr 24. PMID: 15852008

Bertone P, Snyder M: Prospects and challenges in proteomics. Plant Physiol. 2005 Jun. PMID: 15955915

Li L, Deng XW: It runs in the family: regulation of brassinosteroid signaling by the BZR1-BES1 class of transcription factors. Trends Plant Sci. 2005 Jun. PMID: 15949759

Ziegler EC, Ghosh S: Regulating inducible transcription through controlled localization. Sci STKE. 2005 May 17; 2005 May 17. PMID: 15900032

Zhang W, Zheng S, Storz P, Min W: Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor. J Biol Chem. 2005 May 13; 2005 Mar 8. PMID: 15755722

Andrews NW: Membrane resealing: synaptotagmin VII keeps running the show. Sci STKE. 2005 May 3; 2005 May 3. PMID: 15870423

Watson RO, Galán JE: Signal transduction in Campylobacter jejuni-induced cytokine production. Cell Microbiol. 2005 May. PMID: 15839895

DiFedele LM, He J, Bonkowski EL, Han X, Held MA, Bohan A, Menon RK, Denson LA: Tumor necrosis factor alpha blockade restores growth hormone signaling in murine colitis. Gastroenterology. 2005 May. PMID: 15887111

Mehal WZ, Sheikh SZ, Gorelik L, Flavell RA: TGF-beta signaling regulates CD8+ T cell responses to high- and low-affinity TCR interactions. Int Immunol. 2005 May; 2005 Apr 11. PMID: 15824070

Gaines P, Chi J, Berliner N: Heterogeneity of functional responses in differentiated myeloid cell lines reveals EPRO cells as a valid model of murine neutrophil functional activation. J Leukoc Biol. 2005 May; 2005 Jan 26. PMID: 15673544

Rush AM, Dib-Hajj SD, Waxman SG: Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones. J Physiol. 2005 May 1; 2005 Mar 10. PMID: 15760941

Gotoh N, Manova K, Tanaka S, Murohashi M, Hadari Y, Lee A, Hamada Y, Hiroe T, Ito M, Kurihara T, Nakazato H, Shibuya M, Lax I, Lacy E, Schlessinger J: The docking protein FRS2alpha is an essential component of multiple fibroblast growth factor responses during early mouse development. Mol Cell Biol. 2005 May. PMID: 15870281

Hisamoto K, Bender JR: Vascular cell signaling by membrane estrogen receptors. Steroids. 2005 May-Jun; 2005 Mar 16. PMID: 15862821

Wu JJ, Bennett AM: Essential role for mitogen-activated protein (MAP) kinase phosphatase-1 in stress-responsive MAP kinase and cell survival signaling. J Biol Chem. 2005 Apr 22; 2005 Feb 17. PMID: 15722358

Holford M, Li N, Nadkarni P, Zhao H: VitaPad: visualization tools for the analysis of pathway data. Bioinformatics. 2005 Apr 15; 2004 Nov 25. PMID: 15564306

Li X, Zhang R, Luo D, Park SJ, Wang Q, Kim Y, Min W: Tumor necrosis factor alpha-induced desumoylation and cytoplasmic translocation of homeodomain-interacting protein kinase 1 are critical for apoptosis signal-regulating kinase 1-JNK/p38 activation. J Biol Chem. 2005 Apr 15; 2005 Feb 8. PMID: 15701637

Zielinski CE, Jacob SN, Bouzahzah F, Ehrlich BE, Craft J: Naive CD4+ T cells from lupus-prone Fas-intact MRL mice display TCR-mediated hyperproliferation due to intrinsic threshold defects in activation. J Immunol. 2005 Apr 15. PMID: 15814741

Provost E, McCabe A, Stern J, Lizardi I, D'Aquila TG, Rimm DL: Functional correlates of mutation of the Asp32 and Gly34 residues of beta-catenin. Oncogene. 2005 Apr 14. PMID: 15829978

Lima SQ, Miesenböck G: Remote control of behavior through genetically targeted photostimulation of neurons. Cell. 2005 Apr 8. PMID: 15820685

Dong K, Tang LQ, MacGregor GG, Leng Q, Hebert SC: Novel nucleotide-binding sites in ATP-sensitive potassium channels formed at gating interfaces. EMBO J. 2005 Apr 6; 2005 Mar 17. PMID: 15775962

Li H, Cuartas E, Cui W, Choi Y, Crawford TD, Ke HZ, Kobayashi KS, Flavell RA, Vignery A: IL-1 receptor-associated kinase M is a central regulator of osteoclast differentiation and activation. J Exp Med. 2005 Apr 4. PMID: 15809356

D'Alessio A, Al-Lamki RS, Bradley JR, Pober JS: Caveolae participate in tumor necrosis factor receptor 1 signaling and internalization in a human endothelial cell line. Am J Pathol. 2005 Apr. PMID: 15793306

Li W, Sumpio BE: Strain-induced vascular endothelial cell proliferation requires PI3K-dependent mTOR-4E-BP1 signal pathway. Am J Physiol Heart Circ Physiol. 2005 Apr; 2004 Dec 9. PMID: 15591103

Tsvetkov LM, Tsekova RT, Xu X, Stern DF: The Plk1 Polo box domain mediates a cell cycle and DNA damage regulated interaction with Chk2. Cell Cycle. 2005 Apr; 2005 Apr 9. PMID: 15876876

Huang P, Stern MJ: FGF signaling in flies and worms: more and more relevant to vertebrate biology. Cytokine Growth Factor Rev. 2005 Apr; 2005 Mar 26. PMID: 15863031

Eswarakumar VP, Lax I, Schlessinger J: Cellular signaling by fibroblast growth factor receptors. Cytokine Growth Factor Rev. 2005 Apr; 2005 Feb 1. PMID: 15863030

Jülich D, Geisler R, Holley SA, Tübingen 2000 Screen Consortium.: Integrinalpha5 and delta/notch signaling have complementary spatiotemporal requirements during zebrafish somitogenesis. Dev Cell. 2005 Apr. PMID: 15809039

Tang H, Rompani SB, Atkins JB, Zhou Y, Osterwalder T, Zhong W: Numb proteins specify asymmetric cell fates via an endocytosis- and proteasome-independent pathway. Mol Cell Biol. 2005 Apr. PMID: 15798180

Aggarwal S, Chu E: Current therapies for advanced colorectal cancer. Oncology (Williston Park). 2005 Apr. PMID: 15945340

Lee KY, D'Acquisto F, Hayden MS, Shim JH, Ghosh S: PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activation. Science. 2005 Apr 1. PMID: 15802604

Young LH, Li J, Baron SJ, Russell RR: AMP-activated protein kinase: a key stress signaling pathway in the heart. Trends Cardiovasc Med. 2005 Apr. PMID: 16039971

Jacob SN, Choe CU, Uhlen P, DeGray B, Yeckel MF, Ehrlich BE: Signaling microdomains regulate inositol 1,4,5-trisphosphate-mediated intracellular calcium transients in cultured neurons. J Neurosci. 2005 Mar 16. PMID: 15772345

Zhang X, Shan P, Alam J, Fu XY, Lee PJ: Carbon monoxide differentially modulates STAT1 and STAT3 and inhibits apoptosis via a phosphatidylinositol 3-kinase/Akt and p38 kinase-dependent STAT3 pathway during anoxia-reoxygenation injury. J Biol Chem. 2005 Mar 11; 2004 Dec 7. PMID: 15590660

Biederer T: Progress from the postsynaptic side: signaling in synaptic differentiation. Sci STKE. 2005 Mar 8; 2005 Mar 8. PMID: 15755927

Gwira JA, Wei F, Ishibe S, Ueland JM, Barasch J, Cantley LG: Expression of neutrophil gelatinase-associated lipocalin regulates epithelial morphogenesis in vitro. J Biol Chem. 2005 Mar 4; 2005 Jan 6. PMID: 15637066

Baker BJ, Kosmidis EK, Vucinic D, Falk CX, Cohen LB, Djurisic M, Zecevic D: Imaging brain activity with voltage- and calcium-sensitive dyes. Cell Mol Neurobiol. 2005 Mar. PMID: 16050036

Wang L, Arcasoy MO, Watowich SS, Forget BG: Cytokine signals through STAT3 promote expression of granulocyte secondary granule proteins in 32D cells. Exp Hematol. 2005 Mar. PMID: 15730854

Sigworth FJ, Klemic KG: Microchip technology in ion-channel research. IEEE Trans Nanobioscience. 2005 Mar. PMID: 15816178

Giordano FJ: Oxygen, oxidative stress, hypoxia, and heart failure. J Clin Invest. 2005 Mar. PMID: 15765131

Chi H, Flavell RA: Cutting edge: regulation of T cell trafficking and primary immune responses by sphingosine 1-phosphate receptor 1. J Immunol. 2005 Mar 1. PMID: 15728452

Arnsten AF, Ramos BP, Birnbaum SG, Taylor JR: Protein kinase A as a therapeutic target for memory disorders: rationale and challenges. Trends Mol Med. 2005 Mar. PMID: 15760770

DiGiovanna MP, Stern DF, Edgerton SM, Whalen SG, Moore D 2nd, Thor AD: Relationship of epidermal growth factor receptor expression to ErbB-2 signaling activity and prognosis in breast cancer patients. J Clin Oncol. 2005 Feb 20. PMID: 15718311

Ramana CV, Kumar A, Enelow R: Stat1-independent induction of SOCS-3 by interferon-gamma is mediated by sustained activation of Stat3 in mouse embryonic fibroblasts. Biochem Biophys Res Commun. 2005 Feb 18. PMID: 15649407

Broberger C, McCormick DA: Excitatory effects of thyrotropin-releasing hormone in the thalamus. J Neurosci. 2005 Feb 16. PMID: 15716402

Chen Q, Rabach L, Noble P, Zheng T, Lee CG, Homer RJ, Elias JA: IL-11 receptor alpha in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol. 2005 Feb 15. PMID: 15699166

Rubio V, Deng XW: Phy tunes: phosphorylation status and phytochrome-mediated signaling. Cell. 2005 Feb 11. PMID: 15707886

Galán JE: Bacterial toxins and the immune system: show me the in vivo targets. J Exp Med. 2005 Feb 7. PMID: 15699067

Kobayashi KS, Chamaillard M, Ogura Y, Henegariu O, Inohara N, Nuñez G, Flavell RA: Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science. 2005 Feb 4. PMID: 15692051

Paspalas CD, Goldman-Rakic PS: Presynaptic D1 dopamine receptors in primate prefrontal cortex: target-specific expression in the glutamatergic synapse. J Neurosci. 2005 Feb 2. PMID: 15689564

Sreedharan R, Riordan M, Wang S, Thulin G, Kashgarian M, Siegel NJ: Reduced tolerance of immature renal tubules to anoxia by HSF-1 decoy. Am J Physiol Renal Physiol. 2005 Feb; 2004 Oct 5. PMID: 15467004

Patel JC, Galán JE: Manipulation of the host actin cytoskeleton by Salmonella--all in the name of entry. Curr Opin Microbiol. 2005 Feb. PMID: 15694851

Böttcher RT, Niehrs C: Fibroblast growth factor signaling during early vertebrate development. Endocr Rev. 2005 Feb. PMID: 15689573

Piggott DA, Eisenbarth SC, Xu L, Constant SL, Huleatt JW, Herrick CA, Bottomly K: MyD88-dependent induction of allergic Th2 responses to intranasal antigen. J Clin Invest. 2005 Feb. PMID: 15650773

Dardik A, Yamashita A, Aziz F, Asada H, Sumpio BE: Shear stress-stimulated endothelial cells induce smooth muscle cell chemotaxis via platelet-derived growth factor-BB and interleukin-1alpha. J Vasc Surg. 2005 Feb. PMID: 15768016

Lai CC, Edwards AP, DiMaio D: Productive interaction between transmembrane mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor beta receptor. J Virol. 2005 Feb. PMID: 15650217

Jose AM, Koelle MR: Domains, amino acid residues, and new isoforms of Caenorhabditis elegans diacylglycerol kinase 1 (DGK-1) important for terminating diacylglycerol signaling in vivo. J Biol Chem. 2005 Jan 28; 2004 Nov 24. PMID: 15563467

Freeman-Cook LL, Edwards AP, Dixon AM, Yates KE, Ely L, Engelman DM, Dimaio D: Specific locations of hydrophilic amino acids in constructed transmembrane ligands of the platelet-derived growth factor beta receptor. J Mol Biol. 2005 Jan 28. PMID: 15588835

Badou A, Basavappa S, Desai R, Peng YQ, Matza D, Mehal WZ, Kaczmarek LK, Boulpaep EL, Flavell RA: Requirement of voltage-gated calcium channel beta4 subunit for T lymphocyte functions. Science. 2005 Jan 7. PMID: 15637280

Bauer PM, Yu J, Chen Y, Hickey R, Bernatchez PN, Looft-Wilson R, Huang Y, Giordano F, Stan RV, Sessa WC: Endothelial-specific expression of caveolin-1 impairs microvascular permeability and angiogenesis. Proc Natl Acad Sci U S A. 2005 Jan 4; 2004 Dec 22. PMID: 15615855

Miesenböck G, Kevrekidis IG: Optical imaging and control of genetically designated neurons in functioning circuits. Annu Rev Neurosci. 2005. PMID: 16022604

Tsvetkov L, Stern DF: Phosphorylation of Plk1 at S137 and T210 is inhibited in response to DNA damage. Cell Cycle. 2005 Jan; 2005 Jan 5. PMID: 15611664

Irish VF, Day CD: A weed for all reasons. Genome Biol. 2005; 2005 Sep 28. PMID: 16207368

Duman CH, Duman RS: Neurobiology and treatment of anxiety: signal transduction and neural plasticity. Handb Exp Pharmacol. 2005. PMID: 16594263

Neumeister A, Daher RJ, Charney DS: Anxiety disorders: noradrenergic neurotransmission. Handb Exp Pharmacol. 2005. PMID: 16594260

Yono M, Latifpour J, Yoshida M, Ueda S: Age-related alterations in the biochemical and functional properties of the bladder in type 2 diabetic GK rats. J Recept Signal Transduct Res. 2005. PMID: 16194931

Choi J, Walker J, Boichuk S, Kirkiles-Smith N, Torpey N, Pober JS, Alexander L: Human endothelial cells enhance human immunodeficiency virus type 1 replication in CD4+ T cells in a Nef-dependent manner in vitro and in vivo. J Virol. 2005 Jan. PMID: 15596822

McBride SM: Prion protein: a pattern recognition receptor for viral components and uric acid responsible for the induction of innate and adaptive immunity. Med Hypotheses. 2005. PMID: 15913900

Karihaloo A, Nickel C, Cantley LG: Signals which build a tubule. Nephron Exp Nephrol. 2005; 2005 Feb 22. PMID: 15731568

Zamboni DS, Campos MA, Torrecilhas AC, Kiss K, Samuel JE, Golenbock DT, Lauw FN, Roy CR, Almeida IC, Gazzinelli RT: Stimulation of toll-like receptor 2 by Coxiella burnetii is required for macrophage production of pro-inflammatory cytokines and resistance to infection. J Biol Chem. 2004 Dec 24; 2004 Oct 13. PMID: 15485838

Gotoh N, Ito M, Yamamoto S, Yoshino I, Song N, Wang Y, Lax I, Schlessinger J, Shibuya M, Lang RA: Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina. Proc Natl Acad Sci U S A. 2004 Dec 7; 2004 Nov 29. PMID: 15569927

Pasare C, Medzhitov R: Toll-like receptors: linking innate and adaptive immunity. Microbes Infect. 2004 Dec. PMID: 15596124

Wang T, Town T, Alexopoulou L, Anderson JF, Fikrig E, Flavell RA: Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat Med. 2004 Dec; 2004 Nov 21. PMID: 15558055

Schwartz ML, Vaccarino F, Chacon M, Yan WL, Ment LR, Stewart WB: Chronic neonatal hypoxia leads to long term decreases in the volume and cell number of the rat cerebral cortex. Semin Perinatol. 2004 Dec. PMID: 15693394

Tian N: Visual experience and maturation of retinal synaptic pathways. Vision Res. 2004 Dec. PMID: 15535998

Schlessinger J: Common and distinct elements in cellular signaling via EGF and FGF receptors. Science. 2004 Nov 26. PMID: 15567848

Clayton GM, Silverman WR, Heginbotham L, Morais-Cabral JH: Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel. Cell. 2004 Nov 24. PMID: 15550244

Mattoon DR, Lamothe B, Lax I, Schlessinger J: The docking protein Gab1 is the primary mediator of EGF-stimulated activation of the PI-3K/Akt cell survival pathway. BMC Biol. 2004 Nov 18; 2004 Nov 18. PMID: 15550174

Sato A, Iwasaki A: