Developmental Therapeutics Recent Publications

Ren X, Gelinas AD, von Carlowitz I, Janjic N, Pyle AM: Structural basis for IL-1α recognition by a modified DNA aptamer that specifically inhibits IL-1α signaling. Nat Commun. 2017 Oct 9; 2017 Oct 9. PMID: 28993621

Sullivan PF, Agrawal A, Bulik CM, Andreassen OA, Børglum AD, Breen G, Cichon S, Edenberg HJ, Faraone SV, Gelernter J, Mathews CA, Nievergelt CM, Smoller JW, O'Donovan MC, Psychiatric Genomics Consortium.: Psychiatric Genomics: An Update and an Agenda. Am J Psychiatry. 2017 Oct 3; 2017 Oct 3. PMID: 28969442

Biktasova AK, Hajek M, Sewell AB, Gary CS, Bellinger G, Deshpande H, Bhatia AK, Burtness BA, Judson BL, Mehra S, Yarbrough WG, Issaeva N: Demethylation therapy as a targeted treatment for human papilloma virus-associated head and neck cancer. Clin Cancer Res. 2017 Sep 15; 2017 Sep 15. PMID: 28916527

Cascone T, Xu L, Lin HY, Liu W, Tran HT, Liu Y, Howells K, Haddad V, Hanrahan E, Nilsson MB, Cortez MA, Giri U, Kadara H, Saigal B, Park YY, Peng W, Lee JS, Ryan AJ, Jüergensmeier JM, Herbst RS, Wang J, Langley RR, Wistuba II, Lee JJ, Heymach JV: The HGF/c-MET Pathway Is a Driver and Biomarker of VEGFR-inhibitor Resistance and Vascular Remodeling in Non-Small Cell Lung Cancer. Clin Cancer Res. 2017 Sep 15; 2017 May 30. PMID: 28559461

Burslem GM, Crews CM: Small-Molecule Modulation of Protein Homeostasis. Chem Rev. 2017 Sep 13; 2017 Aug 4. PMID: 28777566

Yang J, Milasta S, Hu D, AlTahan AM, Interiano RB, Zhou J, Davidson J, Low J, Lin W, Bao J, Goh P, Nathwani AC, Wang R, Wang Y, Ong SS, Boyd VA, Young B, Das S, Shelat A, Wu Y, Li Z, Zheng JJ, Mishra A, Cheng Y, Qu C, Peng J, Green DR, White S, Guy RK, Chen T, Davidoff AM: Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox. Cancer Res. 2017 Sep 1; 2017 Jul 6. PMID: 28684529

Zhu X, Ding S, Qiu C, Shi Y, Song L, Wang Y, Wang Y, Li J, Wang Y, Sun Y, Qin L, Chen J, Simons M, Min W, Yu L: SUMOylation Negatively Regulates Angiogenesis by Targeting Endothelial NOTCH Signaling. Circ Res. 2017 Sep 1; 2017 Jul 31. PMID: 28760777

Cromm PM, Crews CM: The Proteasome in Modern Drug Discovery: Second Life of a Highly Valuable Drug Target. ACS Cent Sci. 2017 Aug 23; 2017 Aug 7. PMID: 28852696

Shankaran S, Laptook AR, Pappas A, McDonald SA, Das A, Tyson JE, Poindexter BB, Schibler K, Bell EF, Heyne RJ, Pedroza C, Bara R, Van Meurs KP, Huitema CMP, Grisby C, Devaskar U, Ehrenkranz RA, Harmon HM, Chalak LF, DeMauro SB, Garg M, Hartley-McAndrew ME, Khan AM, Walsh MC, Ambalavanan N, Brumbaugh JE, Watterberg KL, Shepherd EG, Hamrick SEG, Barks J, Cotten CM, Kilbride HW, Higgins RD, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.: Effect of Depth and Duration of Cooling on Death or Disability at Age 18 Months Among Neonates With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial. JAMA. 2017 Jul 4. PMID: 28672318

Blasutig IM, Farkona S, Buchbinder EI, Luke JJ, Sharma P, Sznol M: The Phoenix Rises: The Rebirth of Cancer Immunotherapy. Clin Chem. 2017 Jul; 2017 May 17. PMID: 28515097

Asuzu D, Chatain GP, Hayes C, Benzo S, McGlotten R, Keil M, Beri A, Sharma ST, Nieman L, Lodish M, Stratakis C, Lonser RR, Oldfield EH, Chittiboina P: Normalized Early Postoperative Cortisol and ACTH Values Predict Nonremission After Surgery for Cushing Disease. J Clin Endocrinol Metab. 2017 Jul 1. PMID: 28323961

Adams RL, Pirakitikulr N, Pyle AM: Functional RNA structures throughout the Hepatitis C Virus genome. Curr Opin Virol. 2017 Jun; 2017 May 13. PMID: 28511116

Pathan M, Keerthikumar S, Chisanga D, Alessandro R, Ang CS, Askenase P, Batagov AO, Benito-Martin A, Camussi G, Clayton A, Collino F, Di Vizio D, Falcon-Perez JM, Fonseca P, Fonseka P, Fontana S, Gho YS, Hendrix A, Hoen EN, Iraci N, Kastaniegaard K, Kislinger T, Kowal J, Kurochkin IV, Leonardi T, Liang Y, Llorente A, Lunavat TR, Maji S, Monteleone F, Øverbye A, Panaretakis T, Patel T, Peinado H, Pluchino S, Principe S, Ronquist G, Royo F, Sahoo S, Spinelli C, Stensballe A, Théry C, van Herwijnen MJC, Wauben M, Welton JL, Zhao K, Mathivanan S: A novel community driven software for functional enrichment analysis of extracellular vesicles data. J Extracell Vesicles. 2017; 2017 May 26. PMID: 28717418

Anderson CW, Boardman N, Luo J, Park J, Qyang Y: Stem Cells in Cardiovascular Medicine: the Road to Regenerative Therapies. Curr Cardiol Rep. 2017 Apr. PMID: 28324469

Roberts CM, Shahin SA, Wen W, Finlay JB, Dong J, Wang R, Dellinger TH, Zink JI, Tamanoi F, Glackin CA: Nanoparticle delivery of siRNA against TWIST to reduce drug resistance and tumor growth in ovarian cancer models. Nanomedicine. 2017 Apr; 2016 Nov 25. PMID: 27890656

Thakral D, Tae HS: Discovery of a Structurally Unique Small Molecule that Inhibits Protein Synthesis. Yale J Biol Med. 2017 Mar; 2017 Mar 29. PMID: 28356892

Tolisano P, Sondik TM, Dike CC: A Positive Behavioral Approach for Aggression in Forensic Psychiatric Settings. J Am Acad Psychiatry Law. 2017 Mar. PMID: 28270460

Mano O, Clark DA: Graphics Processing Unit-Accelerated Code for Computing Second-Order Wiener Kernels and Spike-Triggered Covariance. PLoS One. 2017; 2017 Jan 9. PMID: 28068420

Bondeson DP, Crews CM: Targeted Protein Degradation by Small Molecules. Annu Rev Pharmacol Toxicol. 2017 Jan 6; 2016 Oct 12. PMID: 27732798

Jerman S, Sun Z: Using Zebrafish to Study Kidney Development and Disease. Curr Top Dev Biol. 2017; 2017 Jan 4. PMID: 28335864

Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M, Bis JC, Blanken LM, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chauhan G, Chen Q, Ching CR, Cuellar-Partida G, Braber AD, Doan NT, Ehrlich S, Filippi I, Ge T, Giddaluru S, Goldman AL, Gottesman RF, Greven CU, Grimm O, Griswold ME, Guadalupe T, Hass J, Haukvik UK, Hilal S, Hofer E, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liao J, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand A, Matarin M, Mather KA, Mattheisen M, Mazoyer B, McKay DR, McWhirter R, Milaneschi Y, Mirza-Schreiber N, Muetzel RL, Maniega SM, Nho K, Nugent AC, Loohuis LM, Oosterlaan J, Papmeyer M, Pappa I, Pirpamer L, Pudas S, Pütz B, Rajan KB, Ramasamy A, Richards JS, Risacher SL, Roiz-Santiañez R, Rommelse N, Rose EJ, Royle NA, Rundek T, Sämann PG, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Thomson R, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Vaidya D, Van der Grond J, Van der Meer D, Van Donkelaar MM, Van Eijk KR, Van Erp TG, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Woldehawariat G, Wolf C, Wolfers T, Xu B, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Aggarwal NT, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Chen C, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Geus EJ, De Jager PL, de Zubicaray GI, Delanty N, Depondt C, DeStefano AL, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Erk S, Espeseth T, Evans DA, Fedko IO, Fernández G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL, Göring HH, Grabe HJ, Green RC, Gruber O, Gudnason V, Guelfi S, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Pol HE, Ikeda M, Ikram MK, Jack CR Jr, Jenkinson M, Johnson R, Jönsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaître H, Liu X, Longo DL, Longstreth WT Jr, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon KL, McMahon FJ, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Mühleisen TW, Müller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, Nöthen MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BW, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schofield PR, Sigurdsson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Srikanth V, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Tiemeier H, Toga AW, Traynor BJ, Troncoso J, Turner JA, Tzourio C, Uitterlinden AG, Hernández MC, Van der Brug M, Van der Lugt A, Van der Wee NJ, Van Duijn CM, Van Haren NE, Van T Ent D, Van Tol MJ, Vardarajan BN, Veltman DJ, Vernooij MW, Völzke H, Walter H, Wardlaw JM, Wassink TH, Weale ME, Weinberger DR, Weiner MW, Wen W, Westman E, White T, Wong TY, Wright CB, Zielke HR, Zonderman AB, Deary IJ, DeCarli C, Schmidt H, Martin NG, De Craen AJ, Wright MJ, Launer LJ, Schumann G, Fornage M, Franke B, Debette S, Medland SE, Ikram MA, Thompson PM: Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci. 2016 Dec; 2016 Oct 3. PMID: 27694991

Ornaghi S, Davis JN, Gorres KL, Miller G, Paidas MJ, van den Pol AN: Mood stabilizers inhibit cytomegalovirus infection. Virology. 2016 Dec; 2016 Sep 19. PMID: 27657833

Guadalupe T, Mathias SR, vanErp TG, Whelan CD, Zwiers MP, Abe Y, Abramovic L, Agartz I, Andreassen OA, Arias-Vásquez A, Aribisala BS, Armstrong NJ, Arolt V, Artiges E, Ayesa-Arriola R, Baboyan VG, Banaschewski T, Barker G, Bastin ME, Baune BT, Blangero J, Bokde AL, Boedhoe PS, Bose A, Brem S, Brodaty H, Bromberg U, Brooks S, Büchel C, Buitelaar J, Calhoun VD, Cannon DM, Cattrell A, Cheng Y, Conrod PJ, Conzelmann A, Corvin A, Crespo-Facorro B, Crivello F, Dannlowski U, de Zubicaray GI, de Zwarte SM, Deary IJ, Desrivières S, Doan NT, Donohoe G, Dørum ES, Ehrlich S, Espeseth T, Fernández G, Flor H, Fouche JP, Frouin V, Fukunaga M, Gallinat J, Garavan H, Gill M, Suarez AG, Gowland P, Grabe HJ, Grotegerd D, Gruber O, Hagenaars S, Hashimoto R, Hauser TU, Heinz A, Hibar DP, Hoekstra PJ, Hoogman M, Howells FM, Hu H, Hulshoff Pol HE, Huyser C, Ittermann B, Jahanshad N, Jönsson EG, Jurk S, Kahn RS, Kelly S, Kraemer B, Kugel H, Kwon JS, Lemaitre H, Lesch KP, Lochner C, Luciano M, Marquand AF, Martin NG, Martínez-Zalacaín I, Martinot JL, Mataix-Cols D, Mather K, McDonald C, McMahon KL, Medland SE, Menchón JM, Morris DW, Mothersill O, Maniega SM, Mwangi B, Nakamae T, Nakao T, Narayanaswaamy JC, Nees F, Nordvik JE, Onnink AM, Opel N, Ophoff R, Paillère Martinot ML, Papadopoulos Orfanos D, Pauli P, Paus T, Poustka L, Reddy JY, Renteria ME, Roiz-Santiáñez R, Roos A, Royle NA, Sachdev P, Sánchez-Juan P, Schmaal L, Schumann G, Shumskaya E, Smolka MN, Soares JC, Soriano-Mas C, Stein DJ, Strike LT, Toro R, Turner JA, Tzourio-Mazoyer N, Uhlmann A, Hernández MV, van den Heuvel OA, van der Meer D, van Haren NE, Veltman DJ, Venkatasubramanian G, Vetter NC, Vuletic D, Walitza S, Walter H, Walton E, Wang Z, Wardlaw J, Wen W, Westlye LT, Whelan R, Wittfeld K, Wolfers T, Wright MJ, Xu J, Xu X, Yun JY, Zhao J, Franke B, Thompson PM, Glahn DC, Mazoyer B, Fisher SE, Francks C: Human subcortical brain asymmetries in 15,847 people worldwide reveal effects of age and sex. Brain Imaging Behav. 2016 Oct 13; 2016 Oct 13. PMID: 27738994

Salazar-Gatzimas E, Chen J, Creamer MS, Mano O, Mandel HB, Matulis CA, Pottackal J, Clark DA: Direct Measurement of Correlation Responses in Drosophila Elementary Motion Detectors Reveals Fast Timescale Tuning. Neuron. 2016 Oct 5. PMID: 27710784

Beck TN, Georgopoulos R, Shagisultanova EI, Sarcu D, Handorf EA, Dubyk C, Lango MN, Ridge JA, Astsaturov I, Serebriiskii IG, Burtness BA, Mehra R, Golemis EA: EGFR and RB1 as Dual Biomarkers in HPV-Negative Head and Neck Cancer. Mol Cancer Ther. 2016 Oct; 2016 Aug 9. PMID: 27507850

Jiang Y, Oron TR, Clark WT, Bankapur AR, D'Andrea D, Lepore R, Funk CS, Kahanda I, Verspoor KM, Ben-Hur A, Koo da CE, Penfold-Brown D, Shasha D, Youngs N, Bonneau R, Lin A, Sahraeian SM, Martelli PL, Profiti G, Casadio R, Cao R, Zhong Z, Cheng J, Altenhoff A, Skunca N, Dessimoz C, Dogan T, Hakala K, Kaewphan S, Mehryary F, Salakoski T, Ginter F, Fang H, Smithers B, Oates M, Gough J, Törönen P, Koskinen P, Holm L, Chen CT, Hsu WL, Bryson K, Cozzetto D, Minneci F, Jones DT, Chapman S, Bkc D, Khan IK, Kihara D, Ofer D, Rappoport N, Stern A, Cibrian-Uhalte E, Denny P, Foulger RE, Hieta R, Legge D, Lovering RC, Magrane M, Melidoni AN, Mutowo-Meullenet P, Pichler K, Shypitsyna A, Li B, Zakeri P, ElShal S, Tranchevent LC, Das S, Dawson NL, Lee D, Lees JG, Sillitoe I, Bhat P, Nepusz T, Romero AE, Sasidharan R, Yang H, Paccanaro A, Gillis J, Sedeño-Cortés AE, Pavlidis P, Feng S, Cejuela JM, Goldberg T, Hamp T, Richter L, Salamov A, Gabaldon T, Marcet-Houben M, Supek F, Gong Q, Ning W, Zhou Y, Tian W, Falda M, Fontana P, Lavezzo E, Toppo S, Ferrari C, Giollo M, Piovesan D, Tosatto SC, Del Pozo A, Fernández JM, Maietta P, Valencia A, Tress ML, Benso A, Di Carlo S, Politano G, Savino A, Rehman HU, Re M, Mesiti M, Valentini G, Bargsten JW, van Dijk AD, Gemovic B, Glisic S, Perovic V, Veljkovic V, Veljkovic N, Almeida-E-Silva DC, Vencio RZ, Sharan M, Vogel J, Kansakar L, Zhang S, Vucetic S, Wang Z, Sternberg MJ, Wass MN, Huntley RP, Martin MJ, O'Donovan C, Robinson PN, Moreau Y, Tramontano A, Babbitt PC, Brenner SE, Linial M, Orengo CA, Rost B, Greene CS, Mooney SD, Friedberg I, Radivojac P: An expanded evaluation of protein function prediction methods shows an improvement in accuracy. Genome Biol. 2016 Sep 7; 2016 Sep 7. PMID: 27604469

Navarrete CT, Wrage LA, Carlo WA, Walsh MC, Rich W, Gantz MG, Das A, Schibler K, Newman NS, Piazza AJ, Poindexter BB, Shankaran S, Sánchez PJ, Morris BH, Frantz ID 3rd, Van Meurs KP, Cotten CM, Ehrenkranz RA, Bell EF, Watterberg KL, Higgins RD, Duara S, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.: Growth Outcomes of Preterm Infants Exposed to Different Oxygen Saturation Target Ranges from Birth. J Pediatr. 2016 Sep; 2016 Jun 22. PMID: 27344218

Mohsenin V: The emerging role of microRNAs in hypoxia-induced pulmonary hypertension. Sleep Breath. 2016 Sep; 2016 May 7. PMID: 27154628

Matjusaitis M, Chin G, Sarnoski EA, Stolzing A: Biomarkers to identify and isolate senescent cells. Ageing Res Rev. 2016 Aug; 2016 May 20. PMID: 27212009

Van Voorhis WC, Adams JH, Adelfio R, Ahyong V, Akabas MH, Alano P, Alday A, Alemán Resto Y, Alsibaee A, Alzualde A, Andrews KT, Avery SV, Avery VM, Ayong L, Baker M, Baker S, Ben Mamoun C, Bhatia S, Bickle Q, Bounaadja L, Bowling T, Bosch J, Boucher LE, Boyom FF, Brea J, Brennan M, Burton A, Caffrey CR, Camarda G, Carrasquilla M, Carter D, Belen Cassera M, Chih-Chien Cheng K, Chindaudomsate W, Chubb A, Colon BL, Colón-López DD, Corbett Y, Crowther GJ, Cowan N, D'Alessandro S, Le Dang N, Delves M, DeRisi JL, Du AY, Duffy S, Abd El-Salam El-Sayed S, Ferdig MT, Fernández Robledo JA, Fidock DA, Florent I, Fokou PV, Galstian A, Gamo FJ, Gokool S, Gold B, Golub T, Goldgof GM, Guha R, Guiguemde WA, Gural N, Guy RK, Hansen MA, Hanson KK, Hemphill A, Hooft van Huijsduijnen R, Horii T, Horrocks P, Hughes TB, Huston C, Igarashi I, Ingram-Sieber K, Itoe MA, Jadhav A, Naranuntarat Jensen A, Jensen LT, Jiang RH, Kaiser A, Keiser J, Ketas T, Kicka S, Kim S, Kirk K, Kumar VP, Kyle DE, Lafuente MJ, Landfear S, Lee N, Lee S, Lehane AM, Li F, Little D, Liu L, Llinás M, Loza MI, Lubar A, Lucantoni L, Lucet I, Maes L, Mancama D, Mansour NR, March S, McGowan S, Medina Vera I, Meister S, Mercer L, Mestres J, Mfopa AN, Misra RN, Moon S, Moore JP, Morais Rodrigues da Costa F, Müller J, Muriana A, Nakazawa Hewitt S, Nare B, Nathan C, Narraidoo N, Nawaratna S, Ojo KK, Ortiz D, Panic G, Papadatos G, Parapini S, Patra K, Pham N, Prats S, Plouffe DM, Poulsen SA, Pradhan A, Quevedo C, Quinn RJ, Rice CA, Abdo Rizk M, Ruecker A, St Onge R, Salgado Ferreira R, Samra J, Robinett NG, Schlecht U, Schmitt M, Silva Villela F, Silvestrini F, Sinden R, Smith DA, Soldati T, Spitzmüller A, Stamm SM, Sullivan DJ, Sullivan W, Suresh S, Suzuki BM, Suzuki Y, Swamidass SJ, Taramelli D, Tchokouaha LR, Theron A, Thomas D, Tonissen KF, Townson S, Tripathi AK, Trofimov V, Udenze KO, Ullah I, Vallieres C, Vigil E, Vinetz JM, Voong Vinh P, Vu H, Watanabe NA, Weatherby K, White PM, Wilks AF, Winzeler EA, Wojcik E, Wree M, Wu W, Yokoyama N, Zollo PH, Abla N, Blasco B, Burrows J, Laleu B, Leroy D, Spangenberg T, Wells T, Willis PA: Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. PLoS Pathog. 2016 Jul; 2016 Jul 28. PMID: 27467575

Newman E, Thompson WK, Bartsch H, Hagler DJ Jr, Chen CH, Brown TT, Kuperman JM, McCabe C, Chung Y, Libiger O, Akshoomoff N, Bloss CS, Casey BJ, Chang L, Ernst TM, Frazier JA, Gruen JR, Kennedy DN, Murray SS, Sowell ER, Schork N, Kenet T, Kaufmann WE, Mostofsky S, Amaral DG, Dale AM, Jernigan TL: Anxiety is related to indices of cortical maturation in typically developing children and adolescents. Brain Struct Funct. 2016 Jul; 2015 Jul 17. PMID: 26183468

Merlino G, Herlyn M, Fisher DE, Bastian BC, Flaherty KT, Davies MA, Wargo JA, Curiel-Lewandrowski C, Weber MJ, Leachman SA, Soengas MS, McMahon M, Harbour JW, Swetter SM, Aplin AE, Atkins MB, Bosenberg MW, Dummer R, Gershenwald JE, Halpern AC, Herlyn D, Karakousis GC, Kirkwood JM, Krauthammer M, Lo RS, Long GV, McArthur G, Ribas A, Schuchter L, Sosman JA, Smalley KS, Steeg P, Thomas NE, Tsao H, Tueting T, Weeraratna A, Xu G, Lomax R, Martin A, Silverstein S, Turnham T, Ronai ZA: The state of melanoma: challenges and opportunities. Pigment Cell Melanoma Res. 2016 Jul; 2016 Apr 17. PMID: 27087480

Fang JS, Gritz EC, Marcelo KL, Hirschi KK: Isolation of Murine Embryonic Hemogenic Endothelial Cells. J Vis Exp. 2016 Jun 17; 2016 Jun 17. PMID: 27341393

Li S, Mo K, Tian H, Chu C, Sun S, Tian L, Ding S, Li TR, Wu X, Liu F, Zhang Z, Xu T, Sun LV: Lmod2 piggyBac mutant mice exhibit dilated cardiomyopathy. Cell Biosci. 2016; 2016 Jun 4. PMID: 27274810

Adams BD, Parsons C, Slack FJ: The tumor-suppressive and potential therapeutic functions of miR-34a in epithelial carcinomas. Expert Opin Ther Targets. 2016 Jun; 2015 Dec 11. PMID: 26652031

Kofler N, Simons M: The expanding role of neuropilin: regulation of transforming growth factor-β and platelet-derived growth factor signaling in the vasculature. Curr Opin Hematol. 2016 May. PMID: 26849476

Kaur A, Webster MR, Marchbank K, Behera R, Ndoye A, Kugel CH 3rd, Dang VM, Appleton J, O'Connell MP, Cheng P, Valiga AA, Morissette R, McDonnell NB, Ferrucci L, Kossenkov AV, Meeth K, Tang HY, Yin X, Wood WH 3rd, Lehrmann E, Becker KG, Flaherty KT, Frederick DT, Wargo JA, Cooper ZA, Tetzlaff MT, Hudgens C, Aird KM, Zhang R, Xu X, Liu Q, Bartlett E, Karakousis G, Eroglu Z, Lo RS, Chan M, Menzies AM, Long GV, Johnson DB, Sosman J, Schilling B, Schadendorf D, Speicher DW, Bosenberg M, Ribas A, Weeraratna AT: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance. Nature. 2016 Apr 14; 2016 Apr 4. PMID: 27042933

Zhang Y, Zhang XF, Fleming MR, Amiri A, El-Hassar L, Surguchev AA, Hyland C, Jenkins DP, Desai R, Brown MR, Gazula VR, Waters MF, Large CH, Horvath TL, Navaratnam D, Vaccarino FM, Forscher P, Kaczmarek LK: Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating. Cell. 2016 Apr 7; 2016 Mar 17. PMID: 26997484

Park SA, Lee JW, Herbst RS, Koo JS: GSK-3α Is a Novel Target of CREB and CREB-GSK-3α Signaling Participates in Cell Viability in Lung Cancer. PLoS One. 2016; 2016 Apr 6. PMID: 27049759

Gritz E, Hirschi KK: Specification and function of hemogenic endothelium during embryogenesis. Cell Mol Life Sci. 2016 Apr; 2016 Feb 5. PMID: 26849156

Okafor M, Wrenn G, Ede V, Wilson N, Custer W, Risby E, Claeys M, Shelp FE, Atallah H, Mattox G, Satcher D: Improving Quality of Emergency Care Through Integration of Mental Health. Community Ment Health J. 2016 Apr; 2015 Dec 28. PMID: 26711094

Toure M, Crews CM: Small-Molecule PROTACS: New Approaches to Protein Degradation. Angew Chem Int Ed Engl. 2016 Feb 5; 2016 Jan 12. PMID: 26756721

Dimitrova N, Gocheva V, Bhutkar A, Resnick R, Jong RM, Miller KM, Bendor J, Jacks T: Stromal Expression of miR-143/145 Promotes Neoangiogenesis in Lung Cancer Development. Cancer Discov. 2016 Feb; 2015 Nov 19. PMID: 26586766

Wu J, Montaniel KR, Saleh MA, Xiao L, Chen W, Owens GK, Humphrey JD, Majesky MW, Paik DT, Hatzopoulos AK, Madhur MS, Harrison DG: Origin of Matrix-Producing Cells That Contribute to Aortic Fibrosis in Hypertension. Hypertension. 2016 Feb; 2015 Dec 22. PMID: 26693821

Price NL, Holtrup B, Kwei SL, Wabitsch M, Rodeheffer M, Bianchini L, Suárez Y, Fernández-Hernando C: SREBP-1c/MicroRNA 33b Genomic Loci Control Adipocyte Differentiation. Mol Cell Biol. 2016 Feb 1; 2016 Feb 1. PMID: 26830228

Chamorro-Jorganes A, Lee MY, Araldi E, Landskroner-Eiger S, Fernández-Fuertes M, Sahraei M, Quiles Del Rey M, van Solingen C, Yu J, Fernández-Hernando C, Sessa WC, Suárez Y: VEGF-Induced Expression of miR-17-92 Cluster in Endothelial Cells Is Mediated by ERK/ELK1 Activation and Regulates Angiogenesis. Circ Res. 2016 Jan 8; 2015 Oct 15. PMID: 26472816

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Karakaya C, Guzeloglu-Kayisli O, Uyar A, Kallen AN, Babayev E, Bozkurt N, Unsal E, Karabacak O, Seli E: Poor ovarian response in women undergoing in vitro fertilization is associated with altered microRNA expression in cumulus cells. Fertil Steril. 2015 Jun; 2015 Apr 22. PMID: 25910568

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Yeo DL, Haider S, Zhen CA: Blunt traumatic aortic injury of right aortic arch in a patient with an aberrant left subclavian artery. Yale J Biol Med. 2015 Mar; 2015 Mar 4. PMID: 25745378

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Ye J, Shi H, Shen Y, Peng C, Liu Y, Li C, Deng K, Geng J, Xu T, Zhuang Y, Zheng B, Tao W: PP6 controls T cell development and homeostasis by negatively regulating distal TCR signaling. J Immunol. 2015 Feb 15; 2015 Jan 21. PMID: 25609840

Cheng CJ, Bahal R, Babar IA, Pincus Z, Barrera F, Liu C, Svoronos A, Braddock DT, Glazer PM, Engelman DM, Saltzman WM, Slack FJ: MicroRNA silencing for cancer therapy targeted to the tumour microenvironment. Nature. 2015 Feb 5; 2014 Nov 17. PMID: 25409146

Barton EE, Reichow B, Schnitz A, Smith IC, Sherlock D: A systematic review of sensory-based treatments for children with disabilities. Res Dev Disabil. 2015 Feb; 2014 Nov 25. PMID: 25460221

Jackson JT, Nasa C, Shi W, Huntington ND, Bogue CW, Alexander WS, McCormack MP: A crucial role for the homeodomain transcription factor Hhex in lymphopoiesis. Blood. 2015 Jan 29; 2014 Dec 3. PMID: 25472970

Stahlhut C, Slack FJ: Combinatorial Action of MicroRNAs let-7 and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation. Cell Cycle. 2015; 2015 Feb 25. PMID: 25714397

Galluzzi L, Bravo-San Pedro JM, Vitale I, Aaronson SA, Abrams JM, Adam D, Alnemri ES, Altucci L, Andrews D, Annicchiarico-Petruzzelli M, Baehrecke EH, Bazan NG, Bertrand MJ, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Bredesen DE, Brenner C, Campanella M, Candi E, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, Di Daniele N, Dixit VM, Dynlacht BD, El-Deiry WS, Fimia GM, Flavell RA, Fulda S, Garrido C, Gougeon ML, Green DR, Gronemeyer H, Hajnoczky G, Hardwick JM, Hengartner MO, Ichijo H, Joseph B, Jost PJ, Kaufmann T, Kepp O, Klionsky DJ, Knight RA, Kumar S, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lugli E, Madeo F, Malorni W, Marine JC, Martin SJ, Martinou JC, Medema JP, Meier P, Melino S, Mizushima N, Moll U, Muñoz-Pinedo C, Nuñez G, Oberst A, Panaretakis T, Penninger JM, Peter ME, Piacentini M, Pinton P, Prehn JH, Puthalakath H, Rabinovich GA, Ravichandran KS, Rizzuto R, Rodrigues CM, Rubinsztein DC, Rudel T, Shi Y, Simon HU, Stockwell BR, Szabadkai G, Tait SW, Tang HL, Tavernarakis N, Tsujimoto Y, Vanden Berghe T, Vandenabeele P, Villunger A, Wagner EF, Walczak H, White E, Wood WG, Yuan J, Zakeri Z, Zhivotovsky B, Melino G, Kroemer G: Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death Differ. 2015 Jan; 2014 Sep 19. PMID: 25236395

Saucier-Sawyer JK, Deng Y, Seo YE, Cheng CJ, Zhang J, Quijano E, Saltzman WM: Systemic delivery of blood-brain barrier-targeted polymeric nanoparticles enhances delivery to brain tissue. J Drug Target. 2015. PMID: 26453169

Flowers GP, Crews CM: Generating and identifying axolotls with targeted mutations using Cas9 RNA-guided nuclease. Methods Mol Biol. 2015. PMID: 25740494

Shankaran S, Laptook AR, Pappas A, McDonald SA, Das A, Tyson JE, Poindexter BB, Schibler K, Bell EF, Heyne RJ, Pedroza C, Bara R, Van Meurs KP, Grisby C, Huitema CM, Garg M, Ehrenkranz RA, Shepherd EG, Chalak LF, Hamrick SE, Khan AM, Reynolds AM, Laughon MM, Truog WE, Dysart KC, Carlo WA, Walsh MC, Watterberg KL, Higgins RD, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.: Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a randomized clinical trial. JAMA. 2014 Dec 24-31. PMID: 25536254

Berg AT, Rychlik K, Levy SR, Testa FM: Complete remission of childhood-onset epilepsy: stability and prediction over two decades. Brain. 2014 Dec; 2014 Oct 22. PMID: 25338950

Fernandez E, Watterberg KL, Faix RG, Yoder BA, Walsh MC, Lacy CB, Osborne KA, Das A, Kendrick DE, Stoll BJ, Poindexter BB, Laptook AR, Kennedy KA, Schibler K, Bell EF, Van Meurs KP, Frantz ID 3rd, Goldberg RN, Shankaran S, Carlo WA, Ehrenkranz RA, Sanchez PJ, Higgins RD: Incidence, management, and outcomes of cardiovascular insufficiency in critically ill term and late preterm newborn infants. Am J Perinatol. 2014 Nov; 2014 Feb 10. PMID: 24515617

Ishiguro K, Lin ZP, Penketh PG, Shyam K, Zhu R, Baumann RP, Zhu YL, Sartorelli AC, Rutherford TJ, Ratner ES: Distinct mechanisms of cell-kill by triapine and its terminally dimethylated derivative Dp44mT due to a loss or gain of activity of their copper(II) complexes. Biochem Pharmacol. 2014 Oct 1; 2014 Aug 15. PMID: 25130544

Juliano CE, Lin H, Steele RE: Generation of transgenic Hydra by embryo microinjection. J Vis Exp. 2014 Sep 11; 2014 Sep 11. PMID: 25285460

Shultz S, Vouloumanos A, Bennett RH, Pelphrey K: Neural specialization for speech in the first months of life. Dev Sci. 2014 Sep; 2014 Feb 27. PMID: 24576182

Stevens TP, Finer NN, Carlo WA, Szilagyi PG, Phelps DL, Walsh MC, Gantz MG, Laptook AR, Yoder BA, Faix RG, Newman JE, Das A, Do BT, Schibler K, Rich W, Newman NS, Ehrenkranz RA, Peralta-Carcelen M, Vohr BR, Wilson-Costello DE, Yolton K, Heyne RJ, Evans PW, Vaucher YE, Adams-Chapman I, McGowan EC, Bodnar A, Pappas A, Hintz SR, Acarregui MJ, Fuller J, Goldstein RF, Bauer CR, O'Shea TM, Myers GJ, Higgins RD, SUPPORT Study Group of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.: Respiratory outcomes of the surfactant positive pressure and oximetry randomized trial (SUPPORT). J Pediatr. 2014 Aug; 2014 Apr 13. PMID: 24725582

Marchand C, Huang SY, Dexheimer TS, Lea WA, Mott BT, Chergui A, Naumova A, Stephen AG, Rosenthal AS, Rai G, Murai J, Gao R, Maloney DJ, Jadhav A, Jorgensen WL, Simeonov A, Pommier Y: Biochemical assays for the discovery of TDP1 inhibitors. Mol Cancer Ther. 2014 Aug; 2014 Jul 14. PMID: 25024006

Apolo AB, Kim JW, Bochner BH, Steinberg SM, Bajorin DF, Kelly WK, Agarwal PK, Koppie TM, Kaag MG, Quinn DI, Vogelzang NJ, Sridhar SS: Examining the management of muscle-invasive bladder cancer by medical oncologists in the United States. Urol Oncol. 2014 Jul; 2014 May 16. PMID: 24840869

Mouti A, Reddihough D, Marraffa C, Hazell P, Wray J, Lee K, Kohn M: Fluoxetine for Autistic Behaviors (FAB trial): study protocol for a randomized controlled trial in children and adolescents with autism. Trials. 2014 Jun 16; 2014 Jun 16. PMID: 24934401

Allred EN, Capone A Jr, Fraioli A, Dammann O, Droste P, Duker J, Gise R, Kuban K, Leviton A, O'Shea TM, Paneth N, Petersen R, Trese M, Stoessel K, Vanderveen D, Wallace DK, Weaver G: Retinopathy of prematurity and brain damage in the very preterm newborn. J AAPOS. 2014 Jun. PMID: 24924276

Burtness B: Targeted agents: management of dermatologic toxicities. J Natl Compr Canc Netw. 2014 May. PMID: 24853219

Grant PJ, Joseph LA, Farmer CA, Luckenbaugh DA, Lougee LC, Zarate CA Jr, Swedo SE: 12-week, placebo-controlled trial of add-on riluzole in the treatment of childhood-onset obsessive-compulsive disorder. Neuropsychopharmacology. 2014 May; 2013 Dec 19. PMID: 24356715

Lee MY, Skoura A, Park EJ, Landskroner-Eiger S, Jozsef L, Luciano AK, Murata T, Pasula S, Dong Y, Bouaouina M, Calderwood DA, Ferguson SM, De Camilli P, Sessa WC: Dynamin 2 regulation of integrin endocytosis, but not VEGF signaling, is crucial for developmental angiogenesis. Development. 2014 Apr; 2014 Mar 5. PMID: 24598168

Lodha A, Sauvé R, Bhandari V, Tang S, Christianson H, Bhandari A, Amin H, Singhal N: Need for supplemental oxygen at discharge in infants with bronchopulmonary dysplasia is not associated with worse neurodevelopmental outcomes at 3 years corrected age. PLoS One. 2014; 2014 Mar 19. PMID: 24646665

Zhou HJ, Chen X, Huang Q, Liu R, Zhang H, Wang Y, Jin Y, Liang X, Lu L, Xu Z, Min W: AIP1 mediates vascular endothelial cell growth factor receptor-3-dependent angiogenic and lymphangiogenic responses. Arterioscler Thromb Vasc Biol. 2014 Mar; 2014 Jan 9. PMID: 24407031

Mehri S, Levi Setti PE, Greco K, Sakkas D, Martinez G, Patrizio P: Correlation between follicular diameters and flushing versus no flushing on oocyte maturity, fertilization rate and embryo quality. J Assist Reprod Genet. 2014 Jan; 2013 Nov 6. PMID: 24189964

Stark AR, Carlo WA, Vohr BR, Papile LA, Saha S, Bauer CR, Oh W, Shankaran S, Tyson JE, Wright LL, Poole WK, Das A, Stoll BJ, Fanaroff AA, Korones SB, Ehrenkranz RA, Stevenson DK, Peralta-Carcelen M, Wilson-Costello DE, Bada HS, Heyne RJ, Johnson YR, Lee KG, Steichen JJ, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network.: Death or neurodevelopmental impairment at 18 to 22 months corrected age in a randomized trial of early dexamethasone to prevent death or chronic lung disease in extremely low birth weight infants. J Pediatr. 2014 Jan; 2013 Aug 27. PMID: 23992673

Stahlhut C, Slack FJ: MicroRNAs and the cancer phenotype: profiling, signatures and clinical implications. Genome Med. 2013; 2013 Dec 30. PMID: 24373327

Gordon I, Vander Wyk BC, Bennett RH, Cordeaux C, Lucas MV, Eilbott JA, Zagoory-Sharon O, Leckman JF, Feldman R, Pelphrey KA: Oxytocin enhances brain function in children with autism. Proc Natl Acad Sci U S A. 2013 Dec 24; 2013 Dec 2. PMID: 24297883

Pu KM, Sava P, Gonzalez AL: Microvascular targets for anti-fibrotic therapeutics. Yale J Biol Med. 2013 Dec 13; 2013 Dec 13. PMID: 24348218

Phelps DL, Ward RM, Williams RL, Watterberg KL, Laptook AR, Wrage LA, Nolen TL, Fennell TR, Ehrenkranz RA, Poindexter BB, Michael Cotten C, Hallman MK, Frantz ID 3rd, Faix RG, Zaterka-Baxter KM, Das A, Bethany Ball M, Michael O'Shea T, Backstrom Lacy C, Walsh MC, Shankaran S, Sánchez PJ, Bell EF, Higgins RD: Pharmacokinetics and safety of a single intravenous dose of myo-inositol in preterm infants of 23-29 wk. Pediatr Res. 2013 Dec; 2013 Sep 4. PMID: 24067395

Udo T, McKee SA, White MA, Masheb RM, Barnes RD, Grilo CM: Sex differences in biopsychosocial correlates of binge eating disorder: a study of treatment-seeking obese adults in primary care setting. Gen Hosp Psychiatry. 2013 Nov-Dec; 2013 Aug 19. PMID: 23969142

Roth-Cline M, Nelson RM: Parental permission and child assent in research on children. Yale J Biol Med. 2013 Sep; 2013 Sep 20. PMID: 24058304

Collins SC: Preimplantation genetic diagnosis: technical advances and expanding applications. Curr Opin Obstet Gynecol. 2013 Jun. PMID: 23429571

Flanagin BA, Dushey CH, Rubin LE, Keggi KJ: Total hip arthroplasty followed by traction and delayed reduction for Crowe IV developmental dysplasia of the hip. J Arthroplasty. 2013 Jun; 2013 Mar 15. PMID: 23498873

Li R, Zhuang Y, Han M, Xu T, Wu X: piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice. Dis Model Mech. 2013 May; 2013 Mar 8. PMID: 23519027

Torii M, Hackett TA, Rakic P, Levitt P, Polley DB: EphA signaling impacts development of topographic connectivity in auditory corticofugal systems. Cereb Cortex. 2013 Apr; 2012 Apr 5. PMID: 22490549

Moriarty Daley A, Sadler LS, Dawn Reynolds H: Tailoring clinical services to address the unique needs of adolescents from the pregnancy test to parenthood. Curr Probl Pediatr Adolesc Health Care. 2013 Apr. PMID: 23522339

Stevens HE, Su T, Yanagawa Y, Vaccarino FM: Prenatal stress delays inhibitory neuron progenitor migration in the developing neocortex. Psychoneuroendocrinology. 2013 Apr; 2012 Aug 19. PMID: 22910687

Graf WD, Nagel SK, Epstein LG, Miller G, Nass R, Larriviere D: Pediatric neuroenhancement: ethical, legal, social, and neurodevelopmental implications. Neurology. 2013 Mar 26; 2013 Mar 13. PMID: 23486879

Weisberg D, Balf-Soran G, Becker W, Brown SE, Sledge W: "I'm talking about pain": sickle cell disease patients with extremely high hospital use. J Hosp Med. 2013 Jan; 2012 Nov 20. PMID: 23169484

Kasinski AL, Slack FJ: miRNA-34 prevents cancer initiation and progression in a therapeutically resistant K-ras and p53-induced mouse model of lung adenocarcinoma. Cancer Res. 2012 Nov 1; 2012 Sep 10. PMID: 22964582

Zhu R, Seow HA, Baumann RP, Ishiguro K, Penketh PG, Shyam K, Sartorelli AC: Design of a hypoxia-activated prodrug inhibitor of O6-alkylguanine-DNA alkyltransferase. Bioorg Med Chem Lett. 2012 Oct 1; 2012 Aug 10. PMID: 22932317

Breaker RR, Conklin DS, Gold L, Söll D, Montimurro JS, Agris PF: RNA science and its applications-a look toward the future: Albany, NY USA, November 3-4, 2011. RNA Biol. 2012 Aug; 2012 Aug 1. PMID: 22858674

Jones D, Li Y, He Y, Xu Z, Chen H, Min W: Mirtron microRNA-1236 inhibits VEGFR-3 signaling during inflammatory lymphangiogenesis. Arterioscler Thromb Vasc Biol. 2012 Mar; 2012 Jan 5. PMID: 22223733

Scahill L, McDougle CJ, Aman MG, Johnson C, Handen B, Bearss K, Dziura J, Butter E, Swiezy NG, Arnold LE, Stigler KA, Sukhodolsky DD, Lecavalier L, Pozdol SL, Nikolov R, Hollway JA, Korzekwa P, Gavaletz A, Kohn AE, Koenig K, Grinnon S, Mulick JA, Yu S, Vitiello B, Research Units on Pediatric Psychopharmacology Autism Network.: Effects of risperidone and parent training on adaptive functioning in children with pervasive developmental disorders and serious behavioral problems. J Am Acad Child Adolesc Psychiatry. 2012 Feb; 2011 Dec 23. PMID: 22265360

Zhu R, Liu MC, Luo MZ, Penketh PG, Baumann RP, Shyam K, Sartorelli AC: 4-nitrobenzyloxycarbonyl derivatives of O(6)-benzylguanine as hypoxia-activated prodrug inhibitors of O(6)-alkylguanine-DNA alkyltransferase (AGT), which produces resistance to agents targeting the O-6 position of DNA guanine. J Med Chem. 2011 Nov 10; 2011 Oct 17. PMID: 21955333

Ren Y, Lee MY, Schliffke S, Paavola J, Amos PJ, Ge X, Ye M, Zhu S, Senyei G, Lum L, Ehrlich BE, Qyang Y: Small molecule Wnt inhibitors enhance the efficiency of BMP-4-directed cardiac differentiation of human pluripotent stem cells. J Mol Cell Cardiol. 2011 Sep; 2011 May 4. PMID: 21569778

Paul R, Roth FP: Characterizing and predicting outcomes of communication delays in infants and toddlers: implications for clinical practice. Lang Speech Hear Serv Sch. 2011 Jul; 2010 Nov 24. PMID: 21106717

Kummar S, Copur MS, Rose M, Wadler S, Stephenson J, O'Rourke M, Brenckman W, Tilton R, Liu SH, Jiang Z, Su T, Cheng YC, Chu E: A phase I study of the chinese herbal medicine PHY906 as a modulator of irinotecan-based chemotherapy in patients with advanced colorectal cancer. Clin Colorectal Cancer. 2011 Jun; 2011 Apr 22. PMID: 21859559

Trang P, Wiggins JF, Daige CL, Cho C, Omotola M, Brown D, Weidhaas JB, Bader AG, Slack FJ: Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice. Mol Ther. 2011 Jun; 2011 Mar 22. PMID: 21427705

Kim M, Kasinski AL, Slack FJ: MicroRNA therapeutics in preclinical cancer models. Lancet Oncol. 2011 Apr. PMID: 21463831

Park J, Gao W, Whiston R, Strom TB, Metcalfe S, Fahmy TM: Modulation of CD4+ T lymphocyte lineage outcomes with targeted, nanoparticle-mediated cytokine delivery. Mol Pharm. 2011 Feb 7; 2010 Dec 8. PMID: 20977190

Mistry PK, Weinreb NJ, Kaplan P, Cole JA, Gwosdow AR, Hangartner T: Osteopenia in Gaucher disease develops early in life: response to imiglucerase enzyme therapy in children, adolescents and adults. Blood Cells Mol Dis. 2011 Jan 15; 2010 Nov 26. PMID: 21112800

Shan G: RNA interference as a gene knockdown technique. Int J Biochem Cell Biol. 2010 Aug; 2009 May 13. PMID: 19442757

Seli E, Robert C, Sirard MA: OMICS in assisted reproduction: possibilities and pitfalls. Mol Hum Reprod. 2010 Aug; 2010 Jun 10. PMID: 20538894

Saif MW, Chu E: Biology of colorectal cancer. Cancer J. 2010 May-Jun. PMID: 20526096

Cota BM, Allen PJ: The developmental origins of health and disease hypothesis. Pediatr Nurs. 2010 May-Jun. PMID: 20687308

Godshalk SE, Melnik-Martinez KV, Pasquinelli AE, Slack FJ: MicroRNAs and cancer: a meeting summary of the eponymous Keystone Conference. Epigenetics. 2010 Feb 16; 2010 Feb 11. PMID: 20168081

Sharon D, Chen R, Snyder M: Systems biology approaches to disease marker discovery. Dis Markers. 2010. PMID: 20534906

Saif MW, Choma A, Salamone SJ, Chu E: Pharmacokinetically guided dose adjustment of 5-fluorouracil: a rational approach to improving therapeutic outcomes. J Natl Cancer Inst. 2009 Nov 18; 2009 Oct 19. PMID: 19841331

Lepus CM, Gibson TF, Gerber SA, Kawikova I, Szczepanik M, Hossain J, Ablamunits V, Kirkiles-Smith N, Herold KC, Donis RO, Bothwell AL, Pober JS, Harding MJ: Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/gammac-/-, Balb/c-Rag1-/-gammac-/-, and C.B-17-scid/bg immunodeficient mice. Hum Immunol. 2009 Oct; 2009 Jun 12. PMID: 19524633

Ishiguro K, Rice AM, Rice KP, Sartorelli AC: Inhibition of all-trans retinoic acid-induced granulocytic differentiation of WEHI-3B D+ cells by forced expression of SCL (TAL1) and GATA-1. Leuk Res. 2009 Sep; 2009 Feb 20. PMID: 19230972

Reichow B, Barton EE, Good L, Wolery M: Brief report: Effects of pressure vest usage on engagement and problem behaviors of a young child with developmental delays. J Autism Dev Disord. 2009 Aug; 2009 Mar 17. PMID: 19291378

Weitzman CC, Schlegel S, Murphy N, Antommaria AH, Brosco JP, Stein MT: When clinicians and a parent disagree on the extent of medical care. J Dev Behav Pediatr. 2009 Jun. PMID: 19525718

Scahill L, Aman MG, McDougle CJ, Arnold LE, McCracken JT, Handen B, Johnson C, Dziura J, Butter E, Sukhodolsky D, Swiezy N, Mulick J, Stigler K, Bearss K, Ritz L, Wagner A, Vitiello B: Trial design challenges when combining medication and parent training in children with pervasive developmental disorders. J Autism Dev Disord. 2009 May; 2008 Dec 19. PMID: 19096921

Marjani SL, Le Bourhis D, Vignon X, Heyman Y, Everts RE, Rodriguez-Zas SL, Lewin HA, Renard JP, Yang X, Tian XC: Embryonic gene expression profiling using microarray analysis. Reprod Fertil Dev. 2009. PMID: 19152742

Ishiguro K, Shyam K, Penketh PG, Sartorelli AC: Development of an O(6)-alkylguanine-DNA alkyltransferase assay based on covalent transfer of the benzyl moiety from [benzene-3H]O(6)-benzylguanine to the protein. Anal Biochem. 2008 Dec 1; 2008 Aug 20. PMID: 18783719

Trang P, Weidhaas JB, Slack FJ: MicroRNAs as potential cancer therapeutics. Oncogene. 2008 Dec. PMID: 19956180

Baumann RP, Penketh PG, Seow HA, Shyam K, Sartorelli AC: Generation of oxygen deficiency in cell culture using a two-enzyme system to evaluate agents targeting hypoxic tumor cells. Radiat Res. 2008 Nov. PMID: 18959466

Brown TE: ADD/ADHD and Impaired Executive Function in Clinical Practice. Curr Psychiatry Rep. 2008 Oct. PMID: 18803914

Penketh PG, Baumann RP, Ishiguro K, Shyam K, Seow HA, Sartorelli AC: Lethality to leukemia cell lines of DNA interstrand cross-links generated by Cloretazine derived alkylating species. Leuk Res. 2008 Oct; 2008 May 13. PMID: 18479747

Wolff AB, Oetgen ME, DeLuca PA: Intraoperative use of 3-d fluoroscopy in the treatment of developmental dislocation of the hip in an infant. Am J Orthop (Belle Mead NJ). 2008 Sep. PMID: 18982190

Bordonaro M, Sartorelli AC: [Fiber, cancer stem cells, and the Wnt signaling continuum: possibilities for colorectal cancer prevention and therapeutics]. Ai Zheng. 2008 Jul. PMID: 18606074

Gill TM, Gahbauer EA: Evaluating disability over discrete periods of time. J Gerontol A Biol Sci Med Sci. 2008 Jun. PMID: 18559633

Bordonaro M, Lazarova DL, Sartorelli AC: Butyrate and Wnt signaling: a possible solution to the puzzle of dietary fiber and colon cancer risk? Cell Cycle. 2008 May 1; 2008 Feb 26. PMID: 18418037

Freeman JB, Garcia AM, Coyne L, Ale C, Przeworski A, Himle M, Compton S, Leonard HL: Early childhood OCD: preliminary findings from a family-based cognitive-behavioral approach. J Am Acad Child Adolesc Psychiatry. 2008 May. PMID: 18356758

Henry MC, Moss RL: Neonatal necrotizing enterocolitis. Semin Pediatr Surg. 2008 May. PMID: 18395659

Mor G: Inflammation and pregnancy: the role of toll-like receptors in trophoblast-immune interaction. Ann N Y Acad Sci. 2008 Apr. PMID: 18443339

Esquela-Kerscher A, Trang P, Wiggins JF, Patrawala L, Cheng A, Ford L, Weidhaas JB, Brown D, Bader AG, Slack FJ: The let-7 microRNA reduces tumor growth in mouse models of lung cancer. Cell Cycle. 2008 Mar 15; 2008 Mar 3. PMID: 18344688

Saif MW: Erlotinib-induced acute hepatitis in a patient with pancreatic cancer. Clin Adv Hematol Oncol. 2008 Mar. PMID: 18391918

Hamrin V, McDonnell MA, Moffett J, Durso S: Psychopharmacological treatment of non-comorbid and comorbid pervasive developmental disorder and pediatric bipolar disorder. Minerva Pediatr. 2008 Feb. PMID: 18277368

Ishiguro K, Sartorelli AC: Relationship between the induction of leukemia cell differentiation and the enhancement of reporter gene expression in 3T3 Swiss cells. Leuk Res. 2008 Jan; 2007 Jul 6. PMID: 17617452

Bordonaro M, Lazarova DL, Sartorelli AC: Hyperinduction of Wnt activity: a new paradigm for the treatment of colorectal cancer? Oncol Res. 2008. PMID: 18488710

Shiller VM: Therapeutic work with a physically abused preschooler. Psychoanal Study Child. 2008. PMID: 19449790

Stefani G: Roles of microRNAs and their targets in cancer. Expert Opin Biol Ther. 2007 Dec. PMID: 18034649

Jacobsen LK, Slotkin TA, Mencl WE, Frost SJ, Pugh KR: Gender-specific effects of prenatal and adolescent exposure to tobacco smoke on auditory and visual attention. Neuropsychopharmacology. 2007 Dec; 2007 Mar 21. PMID: 17375135

Bhandari V, Gavino RG, Nedrelow JH, Pallela P, Salvador A, Ehrenkranz RA, Brodsky NL: A randomized controlled trial of synchronized nasal intermittent positive pressure ventilation in RDS. J Perinatol. 2007 Nov; 2007 Aug 16. PMID: 17703184

Menon S, Chi H, Zhang H, Deng XW, Flavell RA, Wei N: COP9 signalosome subunit 8 is essential for peripheral T cell homeostasis and antigen receptor-induced entry into the cell cycle from quiescence. Nat Immunol. 2007 Nov; 2007 Sep 30. PMID: 17906629

Lee JJ, Chu E: First-line use of anti-epidermal growth factor receptor monoclonal antibodies in metastatic colorectal cancer. Clin Colorectal Cancer. 2007 Oct. PMID: 18021486

Corson TW, Crews CM: Molecular understanding and modern application of traditional medicines: triumphs and trials. Cell. 2007 Sep 7. PMID: 17803898

Patrizio P, Fragouli E, Bianchi V, Borini A, Wells D: Molecular methods for selection of the ideal oocyte. Reprod Biomed Online. 2007 Sep. PMID: 17854537

Bordonaro M, Lazarova DL, Sartorelli AC: The activation of beta-catenin by Wnt signaling mediates the effects of histone deacetylase inhibitors. Exp Cell Res. 2007 May 1; 2007 Feb 22. PMID: 17359971

Mara A, Schroeder J, Chalouni C, Holley SA: Priming, initiation and synchronization of the segmentation clock by deltaD and deltaC. Nat Cell Biol. 2007 May; 2007 Apr 8. PMID: 17417625

Leuenroth SJ, Okuhara D, Shotwell JD, Markowitz GS, Yu Z, Somlo S, Crews CM: Triptolide is a traditional Chinese medicine-derived inhibitor of polycystic kidney disease. Proc Natl Acad Sci U S A. 2007 Mar 13; 2007 Mar 6. PMID: 17360534

Hamrin V, Pachler M: Pediatric bipolar disorder: evidence-based psychopharmacological treatments. J Child Adolesc Psychiatr Nurs. 2007 Feb. PMID: 17284237

Kaplan C: Special issues in contraception: caring for women with disabilities. J Midwifery Womens Health. 2006 Nov-Dec. PMID: 17081935

Cai J, Kirlin WG, Chen Y, Yan X, Jones DP, Sartorelli AC: Overexpression of heat shock factor 1 inhibits butyrate-induced differentiation in colon cancer cells. Cell Stress Chaperones. 2006 Autumn. PMID: 17009592

Saif MW, Merritt J, Robbins J, Stewart J, Schupp J: Phase III multicenter randomized clinical trial to evaluate the safety and efficacy of CoFactor/5-fluorouracil/bevacizumab versus leucovorin/5-fluorouracil/bevacizumab as initial treatment for metastatic colorectal carcinoma. Clin Colorectal Cancer. 2006 Sep. PMID: 17026795

Hines J, Roy M, Cheng H, Agapakis CM, Taylor R, Crews CM: Myriaporone 3/4 structure--activity relationship studies define a pharmacophore targeting eukaryotic protein synthesis. Mol Biosyst. 2006 Aug; 2006 May 26. PMID: 16880957

Nikolov R, Jonker J, Scahill L: [Autistic disorder: current psychopharmacological treatments and areas of interest for future developments]. Rev Bras Psiquiatr. 2006 May; 2006 Jun 12. PMID: 16791391

Blumberg HP, Krystal JH, Bansal R, Martin A, Dziura J, Durkin K, Martin L, Gerard E, Charney DS, Peterson BS: Age, rapid-cycling, and pharmacotherapy effects on ventral prefrontal cortex in bipolar disorder: a cross-sectional study. Biol Psychiatry. 2006 Apr 1; 2006 Jan 18. PMID: 16414030

Zhang J, Qian H, Zhao P, Hong SS, Xia Y: Rapid hypoxia preconditioning protects cortical neurons from glutamate toxicity through delta-opioid receptor. Stroke. 2006 Apr; 2006 Mar 2. PMID: 16514101

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Ishiguro K, Shyam K, Penketh PG, Sartorelli AC: Role of O6-alkylguanine-DNA alkyltransferase in the cytotoxic activity of cloretazine. Mol Cancer Ther. 2005 Nov. PMID: 16275997

Harpaz-Rotem I, Blatt SJ: Changes in representations of a self-designated significant other in long-term intensive inpatient treatment of seriously disturbed adolescents and young adults. Psychiatry. 2005 Fall. PMID: 16253113

Schiller C, Allen PJ: Follow-up of infants prenatally exposed to cocaine. Pediatr Nurs. 2005 Sep-Oct. PMID: 16295162

Rice KP, Penketh PG, Shyam K, Sartorelli AC: Differential inhibition of cellular glutathione reductase activity by isocyanates generated from the antitumor prodrugs Cloretazine and BCNU. Biochem Pharmacol. 2005 May 15. PMID: 15857610

Wells D, Bermudez MG, Steuerwald N, Thornhill AR, Walker DL, Malter H, Delhanty JD, Cohen J: Expression of genes regulating chromosome segregation, the cell cycle and apoptosis during human preimplantation development. Hum Reprod. 2005 May; 2005 Feb 10. PMID: 15705620

Liu MC, Luo MZ, Mozdziesz DE, Dutschman GE, Gullen EA, Cheng YC, Sartorelli AC: Synthesis and biological evaluation of 2',3'-didehydro-2',3'-dideoxy-9-deazaguanosine, a monophosphate prodrug and two analogues, 2',3'-dideoxy-9-deazaguanosine and 2',3'-didehydro-2',3'-dideoxy-9-deazainosine. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 15822619

Liu MC, Luo MZ, Mozdziesz DE, Sartorelli AC: Synthesis and biological evaluation of 2- and 7-substituted 9-deazaadenosine analogues. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 15715198

Baumann RP, Seow HA, Shyam K, Penketh PG, Sartorelli AC: The antineoplastic efficacy of the prodrug Cloretazine is produced by the synergistic interaction of carbamoylating and alkylating products of its activation. Oncol Res. 2005. PMID: 16408696

Breaker RR: Natural and engineered nucleic acids as tools to explore biology. Nature. 2004 Dec 16. PMID: 15602549

Zeng H, Lin ZP, Sartorelli AC: Resistance to purine and pyrimidine nucleoside and nucleobase analogs by the human MDR1 transfected murine leukemia cell line L1210/VMDRC.06. Biochem Pharmacol. 2004 Sep 1. PMID: 15294454

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NP, RECORD Study Group., Münscher C, Potthoff F, Golbach U, Weidenhammer J, Kusterer K, Lundershausen R, O'Neill MC, Goldstein BJ, Wooddell MJ, Strow LJ, Waterhouse BR, Cobitz AR, Wyne KL, Porter LE, Weston WM, Chen T, James RE, Kravitz BG, Pinkowski D, Ruxer J, Mozdzan M, Siejka A, Kaiser M, Häuser C, Jacober SJ, Zagar AJ, Althouse SK, Pinaire JA, Becker RH, Frick AD, Rave K, Moses R, Ways K, Krones R, Basir S, Klein C, Sawicki PT, Rotella CM, Pala L, Dicembrini I, Mannucci E, Annuzzi G, De Natale C, Bozzetto L, Patti L, Cipriano P, Campaigne B, Malone JK, Bai S, Reviriego J, Augendre-Ferrante B, Schreiber SA, Schneider K, Schweitzer MA, Fach EM, Busch K, Karimi Anderesi Z, HOE901/4009 Study Group., Dunseath GJ, Şengül AM, Haupt A, Eckert H, Schweitzer MA, Peiker J, Fritsche A, Janka HU, Plewe G, Kliebe-Frisch C, Maxeiner S, Teng L, Chan C, Ernest CS, Skrivanek Z, Brodows RG, Soon D, Pan CY, Chung KD, Rußmann A, Ryysy L, Hänninen J, Hulme S, Kauppinen-Mäkelin R, Lahdenperä S, Lehtonen 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RJ, Tonkin AM, Harper A, McCarty DJ, Söderberg S, Taylor HR, Chitson P, Alberti GK, Sheetz MJ, Aiello LP, Davis MD, Milton RC, Arora V, Hu K, Girach A, Vignati L, Tyrberg M, Melander A, Lindblad U, Giannarelli R, Coppelli A, Sartini M, Aragona M, Fletcher EL, Ninkovic S, Foster LE, Jones D, De Gooyer T, Stitt A, Vingrys AJ, Wilkinson-Berka JL, Lewandowska AB, Randeva HS, Komorowski J, Lewandowski KC, Jurowski P, Sankar S, Gos R, Kowluru RA, Odenbach S, Shinn S, Oh YS, Kim J, Agardh CD, Hultberg B, Agardh E, Segura RM, Fonollosa A, Berrone E, Beltramo E, Solimine C, Ubertalli A, Islam N, Esteve E, Fernandez M, Recas I, Mauri S, Biarnes F, Junca E, Fernádez-Real J, Rössner S, Stenlof K, Levy B, Perry B, Fitchet M, Chrysos G, Kamaratos A, Lepeniotis G, Kokkoris S, Varytimiadis K, Stasini F, Mikros S, Gianneli D, Tryfinopoulou K, Melidonis A, Nikolopoulou C, Harley K, Ryder R, De P, VanNieuwenhoven FA, Rossing K, Oliver N, Goldschmeding R, Jacobsen PK, Tan F, Liew S, Mukherjee JJ, Lim P, Fröjdö S, Sjölind L, Parkkonen M, Mäkinen V, Tikellis C, FinnDiane Study Group., Nieuwenhoven FA, MacIsaac RJ, Tsalamandris C, McNeil KJ, Panaiotopoulos S, Smith TJ, Ho M, Matthews PG, Jerums G, Hut H, van den Meiracker AH, Nakhjavani M, Behjati J, Esteghamati A, Esfahanian F, Aghamohamadzadeh N, Abbasi M, Kohnert KD, Zander E, Krabbe S, Stehouwer CD, Schalkwijk CG, Saraheimo MT, Krarup Hansen T, Teppo AM, Ebeling P, Hansen BV, Abdella NA, Mojiminiyi OA, Al Dahi WA, Al Mohammedi H, Al Jebely S, Neugebauer-Baba S, Baba T, Ohashi H, Nakajima S, Hesselmann C, Watanabe T, Nargis M, Zaid RB, Voronko OE, Shestakova MV, Shamkhalova MS, Tchugunova LA, Vikulova OK, Nosikov VV, Liu L, Zheng T, Li M, Zhang R, Xiang K, Hadjadj S, Jeunemaitre X, Vervoort G, Veldman B, Berden J, Wetzels J, Singh BM, Holland MR, Baskar V, Oh J, Seo J, Choi K, Baik S, Choi D, Kim N, Matsumoto S, Suetsugu M, Matsutomo R, Pisarczyk-Wiza D, Banaszak A, Wysocki H, Usui H, Shikata K, Okada S, Ogawa D, Yozai K, Kido Y, Nagase R, Ohga S, Tone A, Sasaki M, Wada J, Unno Y, Horiuchi S, McLennan SV, Kamarinos M, Kelly D, Waltham M, Dy V, Yue D, Langham R, Gilbert R, Zdychova J, Komers R, Cresci B, Giannini S, Manuelli C, Giunti S, Pinach S, Ianni Palarchio A, Arnaldi L, Vittone F, Camussi G, Cavallo Perin P, Gruden G, Marshall SM, Jones SE, White KE, Brizzi M, Dentelli P, Rosso A, Calvi C, Gambino R, Cassader M, Salvidio G, Deferrari G, Pegoraro L, Pagano G, Cavallo-Perin P, Oates R, Ellery C, Beebe D, Coutcher J, Qian YZ, Lowe V, Appleton T, Raunig D, O'Neil S, Mylari B, Amazonas RB, Fujita A, Doi A, Matsuno S, Okamoto K, Matsumoto E, Furuta H, Nishi M, Tsuno T, Taniguchi H, Bessho H, Wasén E, Isoaho R, Mattila K, Vahlberg T, Kivelä SL, Irjala K, Rigalleau V, Lasseur C, Perlemoine C, Barthes N, Raffaitin C, Chauveau P, Combe C, Baillet-Blanco L, Beauvieux MC, Gin H, Heinrich S, Steiner T, Ott U, Holdass H, Fellström B, Jardine A, Staffler B, Logan JO, Gimpelewicz C, Stanciu CC, Pena CM, Serafinceanu CC, González-Posada JM, Hernández D, Pérez-Tamajó L, Ló AJ, Herná Alarcó M, Meneses M, Barsotti M, Rizzo G, Schmauss S, Havrdova T, Saudek F, Boucek P, Adamec M, Invitti C, Gilardini L, Parati G, Mazzilli G, Pontiggia B, Sartorio A, Lutgers HL, Groenier KH, Zasadzinska G, Saryusz-Wolska M, Temelkova-Kurktschiev TS, Kurktschiev DP, Majdrakova I, Varbanova T, Todorova B, Bajo-Martinez A, Bernal E, Sanchez O, Ugalde-Canitrot A, Sanchez-Largo E, Coca-Robinot D, Fabregate R, Calbacho M, Marquez J, Saban-Ruiz J, Penesova A, Cizmarova E, Blazicek P, de Jongh RT, Serné EH, Ijzerman RG, de Vries G, Stehouwer CD, Poulsen PL, Andersen NH, Knudsen ST, Helleberg K, Mogensen CE, Waluś M, Idzior-Waluś B, Sztefko K, Cieślik G, Fedak D, Wozniakiewicz E, Lin SD, Guo MY, Lin CJ, Liu XC, Francisco MJ, Rodriguez-Rosas H, Peiró-Martinez I, Macías-Batista A, Harte AL, Rodriguez-Cuenca S, Valsamakis G, Chetty R, Anderson LA, Roca P, Matyka K, LaSalle J, Hershon K, Berman L, Gibson E, Gillen D, Maroni J, Simmons D, Hiukka A, Forder P, Leinonen E, Hilden H, Fruchart J, Fruchart JC, Keech A, Farnier M, Freeman M, Macdonell G, Perevozskaya I, Mitchel Y, Gumbiner B, Didangelos TP, Athyros VG, Mikhailidis DP, Papageorgiou AA, Bouloukos VI, Pehlivanidis AN, Symeonidis AN, Elisaf M, McKenney J, Insull W Jr, Lewin A, Maccubbin D, Lee M, Kush D, Schuster H, Barter PJ, Stender S, Cheung RC, Bonnet J, Morrell JM, Watkins C, Kallend D, Stalenhoef AF, Ballantyne CM, Murin J, Tonstad S, Rose H, Wilpshaar W, Jenkins A, Karschimkus C, Dragicevic G, Rowley K, Wolthers T, Best JD, Voet B, Murdoch SJ, Marcovina SM, Chen HC, Brunzell JD, Caparevic ZV, Kostic ND, Ilic SM, Sartore G, Piarulli F, Cantaro S, Reitano R, Fiore C, Marin R, Bassan S, Manzato E, Fedele D, Solini A, Santini E, Thornalley PJ, Babaei-Jadidi R, Karachalias N, Kupich C, Ahmed N, Fowler AE, Baker AR, Starczynski J, O'Hare P, Szepietowska B, Szelachowska M, Puch U, Glebocka A, Quinn DW, da Silva NF, McTernan CL, Bonser RS, McTernan P, Idzior-Walus B, Woźniakiewicz E, Dimitriou K, Apostolou O, Kontela E, Devangelio E, Gould EM, Serri O, Roussin A, Buithieu J, Mamputu JC, Renier G, Giordanetti S, De Amici E, Poggi G, Turpini C, Fratino P, Garzaniti A, Yin D, Banu I, Paries J, Roman G, Negrean M, Bala CG, Nita C, Kistorp C, Gustafsson F, Chong A, Lip G, Galatius S, Shearer AT, Ari N, Sahilli M, Ceylan-Isık A, Ozansoy G, Karasu-Yilmaz C, Matteucci E, Rosada J, Pallini M, Evangelista I, Cassetti G, Giusti C, Giampietro O, Capaldo B, Galderisi M, Cicala S, Turco A, Imbroinise A, Nosso G, D'Errico A, de Divitiis O, Klimontov VV, Korolyova EA, Jeltova LI, Bondar IA, Tarkun I, Arslan B, Canturk Z, Tarkun P, Agacdiken A, Komsuoglu B, Méneveau N, Pierre-Justin E, Alsayed M, Sabbah R, Paulin S, Marcu S, Tauveron I, Zimmermann C, Schiele F, Seronde ME, Vautrin P, Lusson JR, Thieblot P, Bernard Y, Mistry A, Pye MP, Peovska I, Maksimovic Pavlovic J, Vavlukis M, Pop Gorceva D, Bosevski M, Scognamiglio R, Negut C, de Kreutzenberg S, 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Morosanu A, Darkow T, Vanderplas A, Mamas MA, McElduff P, Burns J, Edwards R, Fitchet A, Young RJ, Gibson JM, New JP, Lichiardopol R, Niculescu N, Totora A, Pencea C, Tomescu I, Cinteza M, Manicardi V, Coscelli C, Navazio A, Catellani E, Michelini M, Dall'Asta D, Guberti A, Piazza A, Gasparini E, Pantaleoni M, Guiducci U, Manari A, Sejil S, Janand-Delenne B, Avierinos JF, Habib G, Labastie N, Vague P, Lassmann-Vague V, Luźniak P, Tatoń J, Wojciechowska Luźniak A, Zairis M, Lyras A, Patsourakos N, Tsirimbis V, Foussas S, Lupón J, Urrutia A, Herreros J, González B, Coll R, Altimir S, Prats M, Valle V, Abreu-Padí C, Rábago G, Ivanova LA, Brasacchio D, Calkin A, Jandeleit-Dahm KA, Harno E, Keenan AK, Li HL, Yu YR, Lu ZM, Zhang XE, Ke L, Liu H, Zhang XX, Jeong IK, Chae MK, Choi MH, Yoo HJ, Kim CD, Yun MR, Na MA, Kang YH, Kong ON, Son SM, Kim IJ, Kim YK, Tanaka N, Hosoi M, Matsuyama Y, Fukumoto M, Yamakita T, Yoshioka K, Ishii T, Sato T, Fujii S, Aoki T, Shibata T, Mizutani N, Suzuki JY, Fowelin JH, Samuelsson P, Brandrup-Wogsen G, Okumura K, Tokmakova AY, Staroverova DN, Antcieferov MB, Shutichina IV, Kuntchevich GI, Vriesendorp TM, Morélis QJ, Legemate DA, Schaper F, Mainas EI, Gkioulmpasanis I, Panagiotou I, Vassilikos G, Skorda L, Sidira M, Christoforidou M, Alaveras A, Artikis V, Evdemon E, Lechleitner M, Koch T, Ebenbichler C, Sturm W, Moretti L, Moruzzo D, Boldrini E, Pandolfo C, Kameyama M, Iwasa R, Cho MH, Nam JY, Kim CS, Kim DM, Ahn CW, Cha BS, Lim SK, Kim KR, Lee HC, Huh KB, Kaplar M, Paragh G, Erdei A, Csongradi E, Garai I, Varga J, Galuska L, Udvardy M, Higa M, Kaneko Y, Hiroi N, Koziarska D, Nowacki P, Majkowska L, Luzniak P, Wojciechowska-Luźniak A, Tushuizen ME, Nieuwland R, Snoeck DP, Sturk A, Diamant M, Aguiar LG, Bahia L, Villela N, Laflor C, Conde C, Bottino D, Dorigo D, Bouskela E, Pu S, Yu HL, Luo ZT, Lam KS, Dan Q, Xu A, Shen J, Cheng K, Xu JY, Thamer C, Stefan N, Haap M, Heller E, Tschritter O, de Prado A, Ortiz A, Ybarra J, Gich I, Pou JM, Ehren M, Meyer MF, Roggenland D, Reinsen B, Klein HH, Rittig K, Stock J, Kocher B, Balletshofer B, Lee J, Shon HS, Chung DS, Nakatani Y, Matsuhisa M, Kaneto H, Hatazaki M, Yoshiuchi K, Katakami N, Kawamori D, Ohtoshi K, Sakamoto K, Matsuoka TA, Ozawa K, Ogawa S, Hori M, Yamasaki Y, Zitouni K, Harry D, Nourooz-Zadeh J, Betteridge JD, Earle KA, Rasmussen LM, Olesen P, Franco L, Corvaja C, Semplicini A, Ceylan-Işık A, Arı N, Rösen P, Lee IK, Kim MJ, Park KG, Jung ED, Shin DW, Jo SR, Obuobie K, Prakash PK, Hanna FW, Evans M, Lazarus J, Varadhan L, Gurushankar J, James D, Sheikh S, Gaede P, Li H, Zou D, Lee SJ, Choi MG, Kim DS, Kim TW, Vilarrasa N, Perez-Maraver M, Mena E, Perez D, Setti G, Buckingham R, Urbančič V, Stefanovska A, Bernjak A, Ažman-Juvan K, Kocijančič A, Glowania A, Filters TS, Fosmark DS, Torjesen PA, Kilhovd B, Berg TJ, Sandvik L, Hanssen KF, Mentink CJ, Kilhovd BK, Kuchmerovska TM, Shymanskyy IO, Donchenko GV, Stepanenko SP, Klimenko AP, Park J, Maingrette F, Deng HC, Lindenmair A, Waldhäusl WK, Freudenthaler A, Baumgartner-Parzer SM, Nizheradze K, Khoruzhenko A, Tronko N, Sheu WH, Ou HC, Shen HM, Lin TM, Wu HS, Yang CH, Mogylnytska L, Mankovsky B, Schmoelzer I, Davies JI, Band M, Morris A, Struthers AD, Prázný M, Škrha J, Kasalová Z, Neelotpol S, Jahan P, Kauschke SG, Harrop CA, Schäfer A, Widder J, Eigenthaler M, Walter U, Uchimura I, Ikebukuro M, Kaibara M, Hirata M, Helal R, Pervin F, Khan AK, Yang X, Jansson PA, Nagaev I, Jack MM, Carvalho E, Sunnerhagen KS, Cam MC, Cushman SW, Smith U, Creely SJ, Farmer J, Creely S, Gustafson B, Kusminski CM, Krusinova E, Wohl P, Klementova M, Lanska V, McDougall C, Thomas SJ, Kelly I, Abbas ZG, Lutale JK, Archibald LK, Karunajeewa H, Stingemore N, Stuccio G, McGechie D, Muller LM, Hak E, Goudzwaard WL, Montorsi F, Homering M, Sprenger K, Goldstein I, Asnaghi V, Ferrari G, Rastaldi M, Gabellini D, Dell'Antonio G, Maestroni A, Ruggieri D, Luzi L, Piemonti L, Zerbini G, Anafaroglu I, Tutuncu NB, Sultana M, Siddiqua N, Iwasaki T, Nakajima A, Yoneda M, Mukasa K, Tanaka S, Sekihara H: 40th EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004. Diabetologia. 2004 Aug. PMID: 27770180

Seow HA, Penketh PG, Belcourt MF, Tomasz M, Rockwell S, Sartorelli AC: Nuclear overexpression of NAD(P)H:quinone oxidoreductase 1 in Chinese hamster ovary cells increases the cytotoxicity of mitomycin C under aerobic and hypoxic conditions. J Biol Chem. 2004 Jul 23; 2004 May 20. PMID: 15155746

Lazarova DL, Bordonaro M, Carbone R, Sartorelli AC: Linear relationship between Wnt activity levels and apoptosis in colorectal carcinoma cells exposed to butyrate. Int J Cancer. 2004 Jul 1. PMID: 15122584

Ishiguro K, Sartorelli AC: Activation of transiently transfected reporter genes in 3T3 Swiss cells by the inducers of differentiation/apoptosis--dimethylsulfoxide, hexamethylene bisacetamide and trichostatin A. Eur J Biochem. 2004 Jun. PMID: 15182353

Euskirchen G: Integrative approaches in molecular medicine. Pharmacogenomics. 2004 Jun. PMID: 15165172

Bordonaro M, Lazarova DL, Sartorelli AC: Pharmacological and genetic modulation of Wnt-targeted Cre-Lox-mediated gene expression in colorectal cancer cells. Nucleic Acids Res. 2004; 2004 May 11. PMID: 15141037

Penketh PG, Shyam K, Baumann RP, Remack JS, Brent TP, Sartorelli AC: 1,2-Bis(methylsulfonyl)-1-(2-chloroethyl)-2-[(methylamino)carbonyl]hydrazine (VNP40101M): I. Direct inhibition of O6-alkylguanine-DNA alkyltransferase (AGT) by electrophilic species generated by decomposition. Cancer Chemother Pharmacol. 2004 Apr; 2003 Dec 24. PMID: 14704831

Paul R, Miles S, Cicchetti D, Sparrow S, Klin A, Volkmar F, Coflin M, Booker S: Adaptive behavior in autism and Pervasive Developmental Disorder-Not Otherwise Specified: microanalysis of scores on the Vineland Adaptive Behavior Scales. J Autism Dev Disord. 2004 Apr. PMID: 15162940

Rice AM, Li J, Sartorelli AC: Combination of all-trans retinoic acid and lithium chloride surmounts a retinoid differentiation block induced by expression of Scl and Rbtn2 transcription factors in myeloid leukemia cells. Leuk Res. 2004 Apr. PMID: 15109540

Sadler LS, Dynes MW, Daley AM, Ickovics JR, Leventhal JM, Reynolds H: Use of home pregnancy tests among adolescent women. MCN Am J Matern Child Nurs. 2004 Jan-Feb. PMID: 14734965

Seow HA, Penketh PG, Baumann RP, Sartorelli AC: Bioactivation and resistance to mitomycin C. Methods Enzymol. 2004. PMID: 15047104

Bordonaro M, Lazarova DL, Carbone R, Sartorelli AC: Modulation of Wnt-specific colon cancer cell kill by butyrate and lithium. Oncol Res. 2004. PMID: 15490974

Nguyen D, Singh S, Zaatreh M, Novotny E, Levy S, Testa F, Spencer SS: Hypothalamic hamartomas: seven cases and review of the literature. Epilepsy Behav. 2003 Jun. PMID: 12791326

Neuber E, Rinaudo P, Trimarchi JR, Sakkas D: Sequential assessment of individually cultured human embryos as an indicator of subsequent good quality blastocyst development. Hum Reprod. 2003 Jun. PMID: 12773464

Holtz KM, Rice AM, Sartorelli AC: Lithium chloride inactivates the 20S proteasome from WEHI-3B D+ leukemia cells. Biochem Biophys Res Commun. 2003 Apr 18. PMID: 12684043

Klin A, Jones W, Schultz R, Volkmar F: The enactive mind, or from actions to cognition: lessons from autism. Philos Trans R Soc Lond B Biol Sci. 2003 Feb 28. PMID: 12639332

Martin A, Koenig K, Anderson GM, Scahill L: Low-dose fluvoxamine treatment of children and adolescents with pervasive developmental disorders: a prospective, open-label study. J Autism Dev Disord. 2003 Feb. PMID: 12708582

Marek GJ, Carpenter LL, McDougle CJ, Price LH: Synergistic action of 5-HT2A antagonists and selective serotonin reuptake inhibitors in neuropsychiatric disorders. Neuropsychopharmacology. 2003 Feb; 2002 Sep 13. PMID: 12589395

Amar AP, Zlokovic BV, Apuzzo ML: Endovascular restorative neurosurgery: a novel concept for molecular and cellular therapy of the nervous system. Neurosurgery. 2003 Feb. PMID: 12535371

Crews CM, Shotwell JB: Small-molecule inhibitors of the cell cycle: an overview. Prog Cell Cycle Res. 2003. PMID: 14593706

Chambers RA, Self DW: Motivational responses to natural and drug rewards in rats with neonatal ventral hippocampal lesions: an animal model of dual diagnosis schizophrenia. Neuropsychopharmacology. 2002 Dec. PMID: 12464446

Lin ZP, Johnson DR, Finch RA, Belinsky MG, Kruh GD, Sartorelli AC: Comparative study of the importance of multidrug resistance-associated protein 1 and P-glycoprotein to drug sensitivity in immortalized mouse embryonic fibroblasts. Mol Cancer Ther. 2002 Oct. PMID: 12481434

Koenig K, Scahill L, Teague B: The challenge of providing continuity in the care of a disabled child: Smith-Lemli-Opitz syndrome. Issues Ment Health Nurs. 2002 Sep. PMID: 12217226

Jose AM: Ribozyme therapy: RNA enzymes to the rescue. Yale J Biol Med. 2002 Jul-Aug. PMID: 12784972

Bordonaro M, Lazarova DL, Augenlicht LH, Sartorelli AC: Cell type- and promoter-dependent modulation of the Wnt signaling pathway by sodium butyrate. Int J Cancer. 2002 Jan 1. PMID: 11774242

Barry DT, Grilo CM, Masheb RM: Gender differences in patients with binge eating disorder. Int J Eat Disord. 2002 Jan. PMID: 11835299

Liu MC, Luo MZ, Mozdziesz DE, Lin TS, Dutschman GE, Gullen EA, Cheng YC, Sartorelli AC: Synthesis of halogen-substituted 3-deazaadenosine and 3-deazaguanosine analogues as potential antitumor/antiviral agents. Nucleosides Nucleotides Nucleic Acids. 2001 Dec. PMID: 11794802

Rice AM, Sartorelli AC: Inhibition of 20 S and 26 S proteasome activity by lithium chloride: impact on the differentiation of leukemia cells by all-trans retinoic acid. J Biol Chem. 2001 Nov 16; 2001 Sep 12. PMID: 11555654

Schwartz TH, Spencer DD: Strategies for reoperation after comprehensive epilepsy surgery. J Neurosurg. 2001 Oct. PMID: 11596956

Penketh PG, Hodnick WF, Belcourt MF, Shyam K, Sherman DH, Sartorelli AC: Inhibition of DNA cross-linking by mitomycin C by peroxidase-mediated oxidation of mitomycin C hydroquinone. J Biol Chem. 2001 Sep 14; 2001 Jul 16. PMID: 11457837

Liu MC, Luo MZ, Mozdziesz DE, Lin TS, Dutschman GE, Gullen EA, Cheng YC, Sartorelli AC: Synthesis and biological evaluation of L- and D-configurations of 2',3'-dideoxy-4'-C-methyl-3'-oxacytidine analogues. Bioorg Med Chem Lett. 2001 Sep 3. PMID: 11527719

Lazarova DL, Bordonaro M, Sartorelli AC: Transcriptional regulation of the vitamin D(3) receptor gene by ZEB. Cell Growth Differ. 2001 Jun. PMID: 11432806

Johnson DR, Finch RA, Lin ZP, Zeiss CJ, Sartorelli AC: The pharmacological phenotype of combined multidrug-resistance mdr1a/1b- and mrp1-deficient mice. Cancer Res. 2001 Feb 15. PMID: 11245453

Bribiescas RG: Reproductive ecology and life history of the human male. Am J Phys Anthropol. 2001. PMID: 11786994

Smith AL, Hayday AC: Genetic dissection of primary and secondary responses to a widespread natural pathogen of the gut, Eimeria vermiformis. Infect Immun. 2000 Nov. PMID: 11035735

Luo MZ, Liu MC, Mozdziesz DE, Lin TS, Dutschman GE, Gullen EA, Cheng YC, Sartorelli AC: Synthesis and biological evaluation of L- and D-configuration 1,3-dioxolane 5-azacytosine and 6-azathymine nucleosides. Bioorg Med Chem Lett. 2000 Sep 18. PMID: 10999490

Horwitz SM, Owens P, Simms MD: Specialized assessments for children in foster care. Pediatrics. 2000 Jul. PMID: 10878150

Gewirtz A, Gossart-Walker S: Home-based treatment for children and families affected by HIV and AIDS. Dealing with stigma, secrecy, disclosure, and loss. Child Adolesc Psychiatr Clin N Am. 2000 Apr. PMID: 10768069

Penketh PG, Shyam K, Sartorelli AC: Comparison of DNA lesions produced by tumor-inhibitory 1,2-bis(sulfonyl)hydrazines and chloroethylnitrosoureas. Biochem Pharmacol. 2000 Feb 1. PMID: 10609557

Stern DF: Tyrosine kinase signalling in breast cancer: ErbB family receptor tyrosine kinases. Breast Cancer Res. 2000; 2000 Mar 25. PMID: 11250707

Perlmutter SJ, Leitman SF, Garvey MA, Hamburger S, Feldman E, Leonard HL, Swedo SE: Therapeutic plasma exchange and intravenous immunoglobulin for obsessive-compulsive disorder and tic disorders in childhood. Lancet. 1999 Oct 2. PMID: 10513708

Martin A, Scahill L, Klin A, Volkmar FR: Higher-functioning pervasive developmental disorders: rates and patterns of psychotropic drug use. J Am Acad Child Adolesc Psychiatry. 1999 Jul. PMID: 10405512

Li J, Finch RA, Sartorelli AC: Role of vitamin D3 receptor in the synergistic differentiation of WEHI-3B leukemia cells by vitamin D3 and retinoic acid. Exp Cell Res. 1999 Jun 15. PMID: 10366427

Koay DC, Sartorelli AC: Functional differentiation signals mediated by distinct regions of the cytoplasmic domain of the granulocyte colony-stimulating factor receptor. Blood. 1999 Jun 1. PMID: 10339483

Amador XF, Kirkpatrick B, Buchanan RW, Carpenter WT, Marcinko L, Yale SA: Stability of the diagnosis of deficit syndrome in schizophrenia. Am J Psychiatry. 1999 Apr. PMID: 10200748

Shyam K, Penketh PG, Shapiro M, Belcourt MF, Loomis RH, Rockwell S, Sartorelli AC: Hypoxia-selective nitrobenzyloxycarbonyl derivatives of 1,2-bis(methylsulfonyl)-1-(2-chloroethyl)hydrazines. J Med Chem. 1999 Mar 11. PMID: 10072691

Farrell ER, Keshishian H: Laser ablation of persistent twist cells in Drosophila: muscle precursor fate is not segmentally restricted. Development. 1999 Jan. PMID: 9847241

Ishiguro K, Sartorelli AC: Coinduction of embryonic and adult-type globin mRNAs by sodium butyrate and trichostatin A in two murine interleukin-3-dependent bone marrow-derived cell lines. Blood. 1998 Dec 1. PMID: 9834245

Sant'Angelo DB, Lucas B, Waterbury PG, Cohen B, Brabb T, Goverman J, Germain RN, Janeway CA Jr: A molecular map of T cell development. Immunity. 1998 Aug. PMID: 9729038

Rousseau ME: Women's midlife health. Reframing menopause. J Nurse Midwifery. 1998 May-Jun. PMID: 9674351

Peterson BS, Cohen DJ: The treatment of Tourette's syndrome: multimodal, developmental intervention. J Clin Psychiatry. 1998. PMID: 9448671

Solnit AJ: Beyond play and playfulness. Psychoanal Study Child. 1998. PMID: 9990826

Ibba M, Bono JL, Rosa PA, Söll D: Archaeal-type lysyl-tRNA synthetase in the Lyme disease spirochete Borrelia burgdorferi. Proc Natl Acad Sci U S A. 1997 Dec 23. PMID: 9405621

Rappa G, Lorico A, Liu MC, Kruh GD, Cory AH, Cory JG, Sartorelli AC: Overexpression of the multidrug resistance genes mdr1, mdr3, and mrp in L1210 leukemia cells resistant to inhibitors of ribonucleotide reductase. Biochem Pharmacol. 1997 Sep 15. PMID: 9310341

Fehon DC, Becker DF, Grilo CM, Walker ML, Levy KN, Edell WS, McGlashan TH: Diagnostic comorbidity in hospitalized adolescents with conduct disorder. Compr Psychiatry. 1997 May-Jun. PMID: 9154369

Lorico A, Rappa G, Flavell RA, Sartorelli AC: Double knockout of the MRP gene leads to increased drug sensitivity in vitro. Cancer Res. 1996 Dec 1. PMID: 8968083

Shachar I, Flavell RA: Requirement for invariant chain in B cell maturation and function. Science. 1996 Oct 4. PMID: 8810244

Volkmar FR: Childhood and adolescent psychosis: a review of the past 10 years. J Am Acad Child Adolesc Psychiatry. 1996 Jul. PMID: 8768343

Penketh PG, Shyam K, Patton CL, Sartorelli AC: Spectrophotometric assay for processes involving changes in hydrogen ion concentration in aqueous solution. Anal Biochem. 1996 Jun 15. PMID: 8660584

Lorico A, Rappa G, Srimatkandada S, Catapano CV, Fernandes DJ, Germino JF, Sartorelli AC: Increased rate of adenosine triphosphate-dependent etoposide (VP-16) efflux in a murine leukemia cell line overexpressing the multidrug resistance-associated protein (MRP) gene. Cancer Res. 1995 Oct 1. PMID: 7671247

McDougle CJ, Kresch LE, Goodman WK, Naylor ST, Volkmar FR, Cohen DJ, Price LH: A case-controlled study of repetitive thoughts and behavior in adults with autistic disorder and obsessive-compulsive disorder. Am J Psychiatry. 1995 May. PMID: 7726318

Li J, Sartorelli AC: Evidence for the glycosylation of the granulocyte colony-stimulating factor receptor. Biochem Biophys Res Commun. 1994 Nov 30. PMID: 7999029

Evans DW, Noam GG, Wertlieb D, Paget KF, Wolf M: Self-perception and adolescent psychopathology: a clinical-developmental perspective. Am J Orthopsychiatry. 1994 Apr. PMID: 8037237

Horwitz SM, Simms MD, Farrington R: Impact of developmental problems on young children's exits from foster care. J Dev Behav Pediatr. 1994 Apr. PMID: 7518472

Dykens EM, Hodapp RM, Evans DW: Profiles and development of adaptive behavior in children with Down syndrome. Am J Ment Retard. 1994 Mar. PMID: 8192903

Renshaw TS: Idiopathic scoliosis in children. Curr Opin Pediatr. 1993 Aug. PMID: 8374665

Luthar SS, Glick M, Zigler E, Rounsaville BJ: Social competence among cocaine abusers: moderating effects of comorbid diagnoses and gender. Am J Drug Alcohol Abuse. 1993. PMID: 8213693

Doane JA, Hill WL Jr, Diamond D: A developmental view of therapeutic bonding in the family: treatment of the disconnected family. Fam Process. 1991 Jun. PMID: 1860482

Sokoloski JA, Lee CW, Handschumacher RE, Nigam A, Sartorelli AC: Effects of uridine on the growth and differentiation of HL-60 leukemia cells. Leuk Res. 1991. PMID: 1961008

Van Cleve SN, Sadler LS: Adolescent parents and toddlers: strategies for intervention. Public Health Nurs. 1990 Mar. PMID: 2320538

Boyers SP, Diamond MP, Lavy G, Russell JB, DeCherney AH: The effect of polyploidy on embryo cleavage after in vitro fertilization in humans. Fertil Steril. 1987 Oct. PMID: 3653419